Canal de sodio
Los canales de sodio son proteínas de membrana esenciales que permiten el paso de iones de sodio (Na+) a través de la membrana celular, generando y propagando señales eléctricas en neuronas, células musculares y otros tejidos excitables. Estos canales son vitales para la iniciación y conducción de potenciales de acción, lo que los hace cruciales en procesos como la transmisión de impulsos nerviosos, la contracción muscular y la función cardíaca. La desregulación de los canales de sodio puede llevar a trastornos neurológicos, arritmias y condiciones de dolor crónico. En CymitQuimica, ofrecemos una variedad de moduladores de canales de sodio para apoyar su investigación en neurobiología, cardiología y manejo del dolor.
Se han encontrado 273 productos para "Canal de sodio".
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Nav1.8-IN-4
CAS:Nav1.8-IN-4 is a potent Nav1.8 channel inhibitor with potential analgesic activity.Nav1.8-IN-4 can be used for pain and neurological related disorders.Fórmula:C20H14F4N2O3Pureza:99.97%Forma y color:SolidPeso molecular:406.33Ref: TM-T77693
1mg56,00€2mg80,00€5mg118,00€10mg178,00€25mg356,00€50mg580,00€100mg888,00€500mg1.783,00€Tocainide hydrochloride
CAS:Tocainide hydrochloride (2-amino-n-(2,6-dimethylphenyl)propanamide hydrochloride) is a sodium channel blocker.Fórmula:C11H17ClN2OPureza:97%Forma y color:SolidPeso molecular:228.72Benzocaine
CAS:Benzocaine is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings.Fórmula:C9H11NO2Pureza:99.16% - 99.88%Forma y color:Rhombohedra From Ether DrypowderPeso molecular:165.19Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Fórmula:C12H21NO8SPureza:99.79% - 99.92%Forma y color:White To Off-White Crystalline PowderPeso molecular:339.36Eleclazine hydrochloride
CAS:Eleclazine hydrochloride (GS 6615 hydrochloride) is a novel inhibitor of late Na+ current (IC50: 0.7 uM).Fórmula:C21H17ClF3N3O3Pureza:99.86%Forma y color:SolidPeso molecular:451.83Ref: TM-T15207
1mg58,00€5mg110,00€1mL*10mM (DMSO)122,00€10mg166,00€25mg268,00€50mg403,00€100mg532,00€200mg705,00€Lamotrigine
CAS:Lamotrigine (BW430C) is an Anti-epileptic Agent and Mood Stabilizer.Fórmula:C9H7Cl2N5Pureza:99.76% - 99.95%Forma y color:White SolidPeso molecular:256.09Lidocaine Hydrochloride hydrate
CAS:Lidocaine Hydrochloride hydrate is an amide local anesthetic, has anti-inflammatory property.Fórmula:C14H22N2O·HCl·H2OPureza:99.95%Forma y color:SolidPeso molecular:288.82Phenytoin sodium
CAS:Phenytoin sodium (Diphantoine) is an inactive stabilizer for voltage-gated sodium channel .Fórmula:C15H11N2NaO2Pureza:99.88% - 99.92%Forma y color:SolidPeso molecular:274.25Mexiletine hydrochloride
CAS:Mexiletine hydrochloride is a lidocaine-like antiarrhythmic (Class IB) and anesthetic, stabilizing heartbeats by inhibiting sodium in cardiac cells.Fórmula:C11H18ClNOPureza:99.88%Forma y color:SolidPeso molecular:215.72Oxcarbazepine
CAS:Oxcarbazepine (GP 47680), an anti-epileptic, reduces CNS disorganized electrical activity.Fórmula:C15H12N2O2Pureza:98.46%Forma y color:White SolidPeso molecular:252.27Ref: TM-T0440
5mg34,00€10mg50,00€1mL*10mM (DMSO)55,00€25mg77,00€50mg96,00€100mg132,00€200mg171,00€500mg222,00€Dibucaine
CAS:Dibucaine (Cinchocaine), a local anesthetic of the amide type, is now usually used for surface anesthesia.Fórmula:C20H29N3O2Pureza:99.69% - 99.88%Forma y color:White SolidPeso molecular:343.46Lidocaine
CAS:Lidocaine, an amide local anesthetic, reduces pain and inflammation by dampening ICAM-1, cytokines, and neutrophil influx.Fórmula:C14H22N2OPureza:99.88% - >99.99%Forma y color:White SolidPeso molecular:234.34DSP-2230
CAS:DSP-2230 is a selective blocker of Nav1.7/Nav1.8.Fórmula:C20H20F3N5O2Pureza:97.14%Forma y color:SolidPeso molecular:419.4Ref: TM-T15174
1mg34,00€5mg66,00€1mL*10mM (DMSO)73,00€10mg99,00€25mg205,00€50mg334,00€100mg537,00€200mg762,00€Tocainide
CAS:Tocainide is a blocker of the sodium channel and used for the treatment of tinnitus.Fórmula:C11H16N2OPureza:99.84%Forma y color:SolidPeso molecular:192.26Vinpocetine
CAS:Vinpocetine (RGH-4405) is a selective inhibitor of cyclic GMP phosphodiesterase (PDE).Fórmula:C22H26N2O2Pureza:99.85% - 99.98%Forma y color:White SolidPeso molecular:350.45Phenazopyridine hydrochloride
CAS:Phenazopyridine HCl, an oral urinary analgesic, may cause nausea, anemia, and liver/kidney toxicity. Possibly carcinogenic.Fórmula:C11H12ClN5Pureza:99.27%Forma y color:SolidPeso molecular:249.7Propafenone
CAS:Propafenone: a drug for ventricular arrhythmias with mild beta-blocker activity, prolongs refractory period, and reduces heart automaticity.Fórmula:C21H27NO3Pureza:99.02%Forma y color:SolidPeso molecular:341.44Ranolazine dihydrochloride
CAS:Ranolazine 2HCl, an antianginal, treats arrhythmia by inhibiting sodium current without changing blood pressure or heart rate.Fórmula:C24H35Cl2N3O4Pureza:99.30% - >99.99%Forma y color:White Crystalline PowderPeso molecular:500.46Meticrane
CAS:Meticrane (Arresten) is a sulphonamide-derivative with thiazide-like diuretic activity.Fórmula:C10H13NO4S2Pureza:99.16%Forma y color:SolidPeso molecular:275.34Amitriptyline hydrochloride
CAS:Amitriptyline hydrochloride (Annoyltin) is the hydrochloride salt of the tricyclic dibenzocycloheptadiene amitriptyline with antidepressant and antinociceptiveFórmula:C20H24ClNPureza:99.39% - 99.94%Forma y color:SolidPeso molecular:313.86Mebeverine hydrochloride
CAS:Mebeverine hydrochloride (Colofac Hydrochloride), a β-phenylethylamine derivative, is a potent α1 repector inhibitor, relaxing the muscles in and around the gutFórmula:C25H35NO5Pureza:99.81% - 99.81%Forma y color:SolidPeso molecular:429.55Disopyramide
CAS:Disopyramide, or Triombrin, a class I anti-arrhythmic with membrane-stabilizing effects, has heart depressant, anticholinergic, and anesthetic properties.Fórmula:C21H29N3OPureza:99.62%Forma y color:White SolidPeso molecular:339.47E 0747 FA
E 0747 FA is an antiarrhythmic compound that inhibits the voltage of action potential Vmax in Purkinje fibers of porcine heart.E 0747 FA inhibits Na channels in cardiac cells.Fórmula:C22H30ClN3O6Pureza:99.96%Forma y color:White SolidPeso molecular:467.94Amiloride hydrochloride
CAS:Amiloride hydrochloride (Amiloride HCl) 是上皮钠通道和尿激酶型纤溶酶原激活物受体的抑制剂，也是 polycystin-2通道阻断剂。Fórmula:C6H9Cl2N7OPureza:99.72% - 99.95%Forma y color:Physical Description Crystalline Solid Or Very Light Yellow Powder (Ntp 1992)Peso molecular:266.09Butamben
CAS:Butamben (Butyl 4-aminobenzoate) is a long-duration local anesthetic used for the treatment of chronic pain.Fórmula:C11H15NO2Pureza:99.43%Forma y color:SolidPeso molecular:193.24Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Fórmula:C11H15NO5Pureza:99.96%Forma y color:Crystals From Benzene SolidPeso molecular:241.24Primidone
CAS:Primidone (NCI-C56360) is a potent anticonvulsant agent.Fórmula:C12H14N2O2Pureza:99.91%Forma y color:SolidPeso molecular:218.25Brompheniramine maleate
CAS:Brompheniramine maleate (Dimotane) is an antagonist against histamine H1 receptors.Fórmula:C16H19BrN2·C4H4O4Pureza:99.80%Forma y color:Crystal PowderPeso molecular:435.31QX-314 chloride
CAS:QX-314 chloride is a membrane-impermeable permanently charged blocker of sodium channel.Fórmula:C16H27ClN2OPureza:99.73%Forma y color:SolidPeso molecular:298.85Articaine hydrochloride
CAS:Articaine hydrochloride (Hoe-045) is a thiophene-containing local anesthetic pharmacologically similar to MEPIVACAINE.Fórmula:C13H21ClN2O3SPureza:99.76%Forma y color:SolidPeso molecular:320.84Phenytoin
CAS:Phenytoin: a non-sedative hydantoin, antiepileptic with anticonvulsant effects, stabilizes neurons, prevents seizure spread, and relaxes muscles.Fórmula:C15H12N2O2Pureza:99.95%Forma y color:White SolidPeso molecular:252.27Nefopam hydrochloride
CAS:Nefopam hydrochloride (Nefopam HCl) is the hydrochloride salt form of nefopam, a centrally-acting, non-opioid benzoxazocine with analgesic activity.Fórmula:C17H20ClNOPureza:99.32% - 99.85%Forma y color:SolidPeso molecular:289.8Flunarizine dihydrochloride
CAS:Flunarizine dihydrochloride: a calcium blocker also targeting calmodulin and histamine H1, used for migraine, vertigo, vascular disease, and epilepsy aid.Fórmula:C26H28Cl2F2N2Pureza:99.53% - 99.99%Forma y color:White SolidPeso molecular:477.42Ropivacaine
CAS:Ropivacaine (LEA-103 HCl) is a local anaesthetic drug belonging to the amino amide group.Fórmula:C17H26N2OPureza:97.75% - >99.99%Forma y color:SolidPeso molecular:274.40PF-04885614
CAS:PF-04885614 is a potent inhibitor of NaV1.8, has potential for neurological and neurodevelopmental diseases treatment.Fórmula:C13H14F3N3OPureza:98.02%Forma y color:SolidPeso molecular:285.27Ref: TM-T12421
2mg39,00€5mg60,00€1mL*10mM (DMSO)60,00€10mg96,00€25mg166,00€50mg299,00€100mg424,00€200mg595,00€Diphenidol hydrochloride
CAS:Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug.Fórmula:C21H28ClNOPureza:99.15% - 99.38%Forma y color:White SolidPeso molecular:345.91Ropivacaine hydrochloride
CAS:Ropivacaine hydrochloride (Ropivacaine monohydrochloride) is the hydrochloride salt of ropivacaine, a local anesthetic of the amide type with analgesic activityFórmula:C17H26N2O·HClPureza:99.85% - 99.95%Forma y color:SolidPeso molecular:310.86Oxybuprocaine hydrochloride
CAS:Oxybuprocaine hydrochloride (Oxybuprocaine HCl), a local anesthetic, is used especially in otolaryngology and ophthalmology.Fórmula:C17H29ClN2O3Pureza:>99.99%Forma y color:SolidPeso molecular:344.88Bupivacaine hydrochloride
CAS:Bupivacaine hydrochloride (Vivacaine) is a long-lasting, amide local anesthetic that blocks sodium channels, inhibiting nerve impulses and sensation.Fórmula:C18H28N2O·HClPureza:99.89% - 99.9%Forma y color:White SolidPeso molecular:324.89NaV1.7 inhibitor-1
CAS:NaV1.7 inhibitor-1, an efficacious inhibitor of voltage-gated sodium channel (NaV) 1.7 (IC50 of 0.6 nM for hNaV1.7).Fórmula:C23H30FNO4SPureza:99.89%Forma y color:SolidPeso molecular:435.55Ref: TM-T12181
1mg99,00€5mg241,00€1mL*10mM (DMSO)265,00€10mg385,00€25mg663,00€50mg888,00€100mg1.305,00€Lidocaine hydrochloride
CAS:Lidocaine HCl: local anesthetic, antiarrhythmic, stronger & longer-lasting than procaine but shorter than bupivacaine/prilocaine.Fórmula:C14H23ClN2OPureza:99.83% - 99.92%Forma y color:SolidPeso molecular:270.798Ceratotoxin-1
Ceratotoxin-1 (CcoTx1) is a peptide toxin that functions as an inhibitor of various voltage-gated sodium channel subtypes.Fórmula:C172H256N52O50S6Pureza:98%Forma y color:SolidPeso molecular:4044.58XPC-7724
XPC-7724 is a selective inhibitor of the Nav1.6 channel, with an IC50 value of 0.078 μM. It is useful in research related to neurological disorders.Fórmula:C25H30FN5O2SPeso molecular:483.21042OD1
Activates rat Nav1.7, human Nav1.4, rat Nav1.6 (EC50: 7, 10, 47 nM); minimal on Nav1.2, 1.3, 1.5 (EC50 >3 μM); blocks fast inactivation; triggers pain.Fórmula:C308H466N90O95S8Pureza:98%Forma y color:SolidPeso molecular:7206.11-(1-Methyl-1h-pyrazol-4-yl)-ethanone
CAS:1-(1-Methyl-1h-pyrazol-4-yl)-ethanone is a high purity biochemical reagent that can be used in research related to life sciences.Fórmula:C6H8N2OPureza:99.92%Forma y color:SolidPeso molecular:124.14Sodium Channel Targeted Library
A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;Forma y color:Odour SolidRef: TM-L7400
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarSodium Channel inhibitor 5
Sodium Channel inhibitor5 (compound 7d) is a potent sodium channel inhibitor with an IC50 of 2.7 μM, playing a significant role in antiarrhythmic research.Fórmula:C24H23F3N4O2Forma y color:SolidPeso molecular:456.17731Nav1.8-IN-6
Nav1.8-IN-6 (Compound 2j) is a novel pyridinone amide Nav1.8 channel inhibitor with IC50 values of 513.33 nM in the resting state and 471.81 nM in the partially activated state. Nav1.8-IN-6 also exhibits analgesic activity.Fórmula:C19H17F6N3O2Forma y color:SolidPeso molecular:433.1225GpTx-1
CAS:GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].Fórmula:C176H271N53O45S7Pureza:98%Forma y color:SolidPeso molecular:4073.82Phrixotoxin 3
CAS:Potent NaV blocker: IC50 - 0.6 nM (NaV1.2), 42 nM (NaV1.3), 72 nM (NaV1.5); voltage-dependent inhibition.Fórmula:C176H269N51O48S6Pureza:98%Forma y color:SolidPeso molecular:4059.74
