Canal de sodio
Los canales de sodio son proteínas de membrana esenciales que permiten el paso de iones de sodio (Na+) a través de la membrana celular, generando y propagando señales eléctricas en neuronas, células musculares y otros tejidos excitables. Estos canales son vitales para la iniciación y conducción de potenciales de acción, lo que los hace cruciales en procesos como la transmisión de impulsos nerviosos, la contracción muscular y la función cardíaca. La desregulación de los canales de sodio puede llevar a trastornos neurológicos, arritmias y condiciones de dolor crónico. En CymitQuimica, ofrecemos una variedad de moduladores de canales de sodio para apoyar su investigación en neurobiología, cardiología y manejo del dolor.
Se han encontrado 202 productos de "Canal de sodio"
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λ-Cyhalothrin
CAS:<p>λ-Cyhalothrin (Icon) is a type II synthetic pyrethroid insecticide featuring a high-efficiency, broad-spectrum formula with an α-cyano group.</p>Fórmula:C23H19ClF3NO3Pureza:99.76%Forma y color:SolidPeso molecular:449.85Rimeporide
CAS:<p>Rimeporide (EMD-87580) (EMD-87580) is a potent and selective Sodium hydrogen exchange 1 (NHE-1) inhibitor.</p>Fórmula:C11H15N3O5S2Pureza:97.66%Forma y color:SolidPeso molecular:333.38Flecainide hydrochloride
CAS:<p>Flecainide is a medication used to prevent and treat abnormally fast heart rates. This includes ventricular and supraventricular tachycardias.</p>Fórmula:C17H21ClF6N2O3Pureza:97.79%Forma y color:SolidPeso molecular:450.81Raxatrigine
CAS:<p>Raxatrigine (CNV 1014802) has been investigated for the treatment of Bipolar Disorder and Bipolar Depression.</p>Fórmula:C18H19FN2O2Pureza:98% - 99.43%Forma y color:SolidPeso molecular:314.35N-Me-aminopyrimidinone9
CAS:<p>N-Me-aminopyrimidinone9 is a sodium channel antagonist</p>Fórmula:C16H21N3OSPureza:99.21%Forma y color:SolidPeso molecular:303.42Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Fórmula:C18H28N2OPureza:99.72%Forma y color:SolidPeso molecular:288.43Propafenone hydrochloride
CAS:<p>Propafenone hydrochloride (Arythmol8) is a classic anti-arrhythmic medication, which treats illnesses associated with rapid heartbeats such as atrial.</p>Fórmula:C21H27NO3·HClPureza:99.67%Forma y color:White SolidPeso molecular:377.9Benzocaine xHCl(94-09-7(free base))
<p>Benzocaine shares a common receptor with all othe rLAs in the voltage-gated Na+ channel(IC50 of 0.8 mM tested with a potential of +30 mV).</p>Fórmula:C9H11NO2·xHClPureza:99.37%Forma y color:SolidPeso molecular:N/AVX-150
CAS:<p>VX-150 is a highly selective NaV1.8 inhibitor relative to the other sodium channel subtypes (>400-fold).</p>Fórmula:C21H17F4N2O7PPureza:97.58%Forma y color:SolidPeso molecular:516.34PF-01247324
CAS:<p>PF-01247324 is a selective and orally bioavailable Nav1.8 channel blocker (IC50: 196 nM).</p>Fórmula:C13H10Cl3N3OPureza:99.22%Forma y color:SolidPeso molecular:330.6PF 05089771
CAS:<p>PF 05089771 is a Selective inhibitor of Nav1.7 (IC50 = 11 nM) that interacts with the voltage-sensor domain of domain IV.</p>Fórmula:C18H12Cl2FN5O3S2Pureza:99.03% - 99.42%Forma y color:SolidPeso molecular:500.35PF-05186462
CAS:<p>PF-05186462 (PF-05150122) is a potent, state-dependent, subtype selective Nav1.7 inhibitor with IC50 of 21 nM, no significant activity against Nav1.5.</p>Fórmula:C19H10ClF4N5O3S2Pureza:99.10% - 99.37%Forma y color:SolidPeso molecular:531.89Ralfinamide mesylate
CAS:<p>Ralfinamide mesylate (FCE-26742A (mesylate)) is an orally available Na+ channel blocker.</p>Fórmula:C18H23FN2O5SPureza:99.83%Forma y color:SolidPeso molecular:398.45Ajmaline
CAS:<p>Ajmaline, a class Ia anti-arrhythmic, diagnoses Brugada syndrome and treats tachycardia; inhibits cardiac Kv1.5/Kv4.3 channels.</p>Fórmula:C20H26N2O2Pureza:99.67% - 99.87%Forma y color:SolidPeso molecular:326.43ICA-121431
CAS:<p>ICA-121431: a potent Nav1.7 inhibitor (IC50=19 nM for rat), minimal effect on human Nav1.5/Nav1.7.</p>Fórmula:C23H19N3O3S2Pureza:98.06%Forma y color:SolidPeso molecular:449.55(+)-Kavain
CAS:<p>(+)-Kavain ((R)-KAWAIN) is one of the six major kavalactones found in the Piper methysticum (kava) plant; reversible inhibitor of MAO-B.</p>Fórmula:C14H14O3Pureza:97% - ≥95%Forma y color:White Fine PowderPeso molecular:230.26Benzamil
CAS:<p>Benzamil blocks ENaC, inhibiting sodium transport (IC50=4 nM) and binds with Kd=5 nM to bovine kidney membranes.</p>Fórmula:C13H14ClN7OPureza:99.79%Forma y color:SolidPeso molecular:319.7520(S)-Ginsenoside Rg3
CAS:<p>20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells.</p>Fórmula:C42H72O13Pureza:98.11% - 99.93%Forma y color:SolidPeso molecular:785.01Dronedarone
CAS:<p>Dronedarone (SR 33589) is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.</p>Fórmula:C31H44N2O5SPureza:98.85% - 99.58%Forma y color:SolidPeso molecular:556.76Evenamide
CAS:<p>Evenamide (NW-3509) is a sodium channel blocker. Which shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.</p>Fórmula:C16H26N2O2Pureza:96.74% - 99.15%Forma y color:SolidPeso molecular:278.39Metaflumizone
CAS:<p>Metaflumizone (BAS-320I) is a sodium channel blocker insecticide.</p>Fórmula:C24H16F6N4O2Pureza:98.73%Forma y color:SolidPeso molecular:506.40Cyfluthrin
CAS:<p>Cyfluthrin binds to voltage-sensitive sodium channel such as Nav 1.8 sodium channel and modify their gating kinetics, thereby disrupting nerve function of pests</p>Fórmula:C22H18Cl2FNO3Pureza:99.76%Forma y color:SolidPeso molecular:434.29A-803467
CAS:<p>A-803467 is a selective NaV1.8 channel blocker.</p>Fórmula:C19H16ClNO4Pureza:96.94% - 98%Forma y color:SolidPeso molecular:357.79Metergoline
CAS:<p>Metergoline (Methergoline) is a dopamine agonist and serotonin antagonist.</p>Fórmula:C25H29N3O2Pureza:99.83% - 99.97%Forma y color:SolidPeso molecular:403.52Tenapanor
CAS:<p>Tenapanor (RDX 5791), an NHE3 inhibitor, regulates sodium in the gut and kidney with a strong preclinical safety record and minimal side effects.</p>Fórmula:C50H66Cl4N8O10S2Pureza:99.49% - 99.85%Forma y color:SolidPeso molecular:1145.05Dimethyl lithospermate B
CAS:<p>Dimethyl lithospermate B (dmLSB) is a selective Na+ channel agonist.</p>Fórmula:C38H34O16Pureza:98.34% - 99.62%Forma y color:SolidPeso molecular:746.67Eslicarbazepine Acetate
CAS:<p>Eslicarbazepine Acetate (Zebinix) is an anticonvulsant medication approved for use as an adjunctive therapy for partial-onset seizures.</p>Fórmula:C17H16N2O3Pureza:99.58% - >99.99%Forma y color:White To Off-White SolidPeso molecular:296.32Nicainoprol
CAS:<p>Nicainoprol (RU-42924) is a fast-sodium-channel blocking drug. Nicainoprol is a potent antiarrhythmic agent.</p>Fórmula:C21H27N3O3Pureza:99.54%Forma y color:SolidPeso molecular:369.46Sodium ionophore III
CAS:<p>Sodium ionophore III (ETH2120) is a Na+ ionophore suitable for the test of sodium activity in plasma, serum, and blood.</p>Fórmula:C34H52N2O4Pureza:99.51% - 99.78%Forma y color:SolidPeso molecular:552.79BI 01383298
CAS:<p>BI 01383298 is a selective inhibitor of the sodium-citrate co-transporter (SLC13A5).</p>Fórmula:C19H19Cl2FN2O3SPureza:99.71%Forma y color:SolidPeso molecular:445.34GS967
CAS:<p>GS967 is a potent, and selective inhibitor of cardiac late sodium current (late INa ).</p>Fórmula:C14H7F6N3OPureza:98% - >99.99%Forma y color:SolidPeso molecular:347.22Ranolazine
CAS:<p>Ranolazine (RS 43285-003) inhibits calcium uptake, treats chronic angina by targeting sodium/calcium channels to modulate intracellular sodium.</p>Fórmula:C24H33N3O4Pureza:98.13%Forma y color:White SolidPeso molecular:427.54AZ194
CAS:<p>CRMP2-Ubc9-NaV1.7 inhibitor 194, is a CRMP2-Ubc9-NaV1.7 inhibitor.</p>Fórmula:C34H31F2N3O3Pureza:99.61%Forma y color:SolidPeso molecular:567.62RY785
CAS:<p>RY785 is a potent and selective inhibitor of voltage-gated potassium channel such as KV2.2 (IC50 = 50 nM). RY785 may be used in pain relief studies.</p>Fórmula:C21H20N4O2SPureza:99.78%Forma y color:SolidPeso molecular:392.476-Benzoylheteratisine
CAS:<p>6-Benzoylheteratisine (Heteratisan-14-one, 6-(benzoyloxy)-20-ethyl-8-hydroxy-1-methoxy-4-meth) is a Aconitum alkaloid.</p>Fórmula:C29H37NO6Pureza:99.87%Forma y color:SolidPeso molecular:495.61Benzonatate
CAS:<p>Benzonatate is an antagonist of sodium channel protein.</p>Fórmula:C30H53NO11Pureza:99.92%Forma y color:Colorless To Faintly Yellow Oil LiquidPeso molecular:603.74PF-06869206
CAS:<p>PF-06869206 is an oral selective inhibitor of the sodium-phosphate cotransporter NaPi2a (SLC34A1, IC50: 380 nM).</p>Fórmula:C15H14ClF3N4O2Pureza:99.79% - 99.88%Forma y color:SolidPeso molecular:374.75Levobupivacaine hydrochloride
CAS:<p>Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a reversible neuronal sodium channel inhibitor, used as a long-acting local anesthetic.</p>Fórmula:C18H28N2O·HClPureza:99.74%Forma y color:White Crystalline PowderPeso molecular:324.893-Deoxyaconitine
CAS:<p>3- Deoxyaconitine is a derivative of Aconitine (A189875), which activates tetrodotoxin-sensitive Na+ channels, inducing presynaptic depolarization, thus</p>Fórmula:C34H47NO10Pureza:98.31%Forma y color:SolidPeso molecular:629.74Ralfinamide
CAS:<p>Ralfinamide (Priralfinamide) is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.</p>Fórmula:C17H19FN2O2Pureza:99.41%Forma y color:SolidPeso molecular:302.34Riluzole
CAS:<p>Riluzole (RP-54274) is an anticonvulsant, glutamate antagonist, and prolongs ALS patient survival.</p>Fórmula:C8H5F3N2OSPureza:99.71% - 99.88%Forma y color:PowderPeso molecular:234.2Benzocaine N-Glucoside (a/b mixture)
CAS:Producto controlado<p>Stability Hygroscopic<br>Applications The N-Glucoside of Benzocaine (B202970) with anesthetic activity. A potential sun-screening agent.<br>References Rybczynska, B. et al.: Parfum. Kosm., 48, 125 (1967); Nikolin, A. et al.: Glas. Hemi. Tehnol. Bosne Herceg., 16, 93 (1968);<br></p>Fórmula:C15H21NO7Forma y color:NeatPeso molecular:327.33Propoxycaine hydrochloride
CAS:<p>Propoxycaine hydrochloride is an ester local anesthetic that inhibits voltage-gated sodium channels, modulates nerve impulses, and induces loss of sensation.</p>Fórmula:C16H27ClN2O3Pureza:97.25%Forma y color:SolidPeso molecular:330.85Eleclazine
CAS:<p>Eleclazine (GS-6615) is a novel and selective voltage-gated sodium channel inhibitor with antiarrhythmic properties that reduces peak sodium current (INaP).</p>Fórmula:C21H16F3N3O3Pureza:98.67%Forma y color:SolidPeso molecular:415.37Deacetamide Acetonitrile-pentisomide
CAS:Producto controlado<p>Applications Deacetamide Acetonitrile-pentisomide is an intermediate in the synthesis of Pentisomide (P275600). Pentisomide is a sodium channel blocker; derivative of disopyramide. Antiarrhythmic (class I).<br>References Kuhlkamp, V., et al.: Int. J. Cardiol., 36, 69 (1992); Yuan, S., et al.: Cardiovasc. Drug Rev., 11, 74 (1993)<br></p>Fórmula:C19H31N3Forma y color:NeatPeso molecular:301.47N-(Chloroacetyl)-2,5-dimethylaniline
CAS:Producto controlado<p>Applications N-(Chloroacetyl)-2,5-dimethylaniline is an intermediate in the synthesis of impurities of Lidocaine (L397800), an anesthetic local agent and antiarrythmic class IB agent.<br>References Groningsson, K., et al.: Anal. Profiles Drug Subs., 14, 207 (1985), Davies, P.S., et al.: Drugs, 64, 937 (2004),<br></p>Fórmula:C10H12ClNOForma y color:NeatPeso molecular:197.663-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene
CAS:Producto controlado<p>Applications 3-(2-Chloropropionyl)amino-4-methyl-2-methoxycarbonylthiophene is an intermediate in the synthesis of Articaine-d7 Hydrochloride which is the labelled form of Articaine Hydrochloride (A777905). Articaine Hydrochloride is the Hydrochloride Salt of Articaine (A777900). Articaine is an amide based short-acting local anesthetic use for regional anaesthesia in day-case settings such arthroscopy, hand, food surgery and in dentistry.<br>References Malamed, S.F., et al.: J. Am. Dent. Assoc., 132, 177 (2001); Luan, F., et al.: Bioorg. Med. Chem., 21, 1870 (2013)<br></p>Fórmula:C10H12ClNO3SForma y color:NeatPeso molecular:261.73Methocarbamol D5
CAS:<p>Methocarbamol is a central muscle relaxant. Methocarbamol D5 is deuterium labeled Methocarbamol.</p>Fórmula:C11H15NO5Pureza:98%Forma y color:SolidPeso molecular:246.27Propafenone D7 hydrochloride
CAS:<p>Propafenone D7 hydrochloride is the deuterium labeled Propafenone, and is a classic anti-arrhythmic medication.</p>Fórmula:C21H28ClNO3Pureza:98%Forma y color:SolidPeso molecular:384.95
