Canal de calcio
Los canales de calcio son proteínas de membrana que regulan el flujo de iones de calcio hacia dentro y fuera de las células, lo cual es esencial para diversas funciones celulares, como la contracción muscular, la liberación de neurotransmisores y la expresión génica. La desregulación de la actividad de los canales de calcio está asociada con condiciones como la hipertensión, las arritmias cardíacas y los trastornos neurológicos. En CymitQuimica, ofrecemos una amplia selección de moduladores de canales de calcio para apoyar su investigación en salud cardiovascular, neurobiología y transducción de señales.
Se han encontrado 493 productos de "Canal de calcio"
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NAADP tetrasodium salt
CAS:<p>Ca2+ mobilizing agent</p>Fórmula:C21H27N6O18P3Pureza:98%Forma y color:SolidPeso molecular:744.39Ryanodine
CAS:<p>Ryanodine: a diterpenoid modulating Ca2+ release via ryanodine receptors; concentration-dependent effects; found in Ryania speciosa; toxic.</p>Fórmula:C25H35NO9Pureza:98%Forma y color:White SolidPeso molecular:493.553Ion Channel Targeted Library
<p>A unique collection of 931 compounds targeting ion channels for research in ion channels-related diseases and ion channel drug discovery;</p>Forma y color:Odour SolidCalcium Channel Compound Library
<p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>Forma y color:Odour SolidKT-362 free base
CAS:<p>KT-362 is a calcium channel blocker with antihypertensive properties that can be used in the study of cardiovascular disease.</p>Fórmula:C22H28N2O3SPureza:99.76%Forma y color:SoildPeso molecular:400.53Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Fórmula:C153H266N38O38S2Forma y color:SolidPeso molecular:3310.11Fasudil
CAS:<p>Fasudil (HA-1077) is a potent inhibitor of ROCK1, PKA, PKC, and MLCK.</p>Fórmula:C14H17N3O2SPureza:99.79% - 99.84%Forma y color:SolidPeso molecular:291.37Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Fórmula:C20H25ClN2O5·C6H6O3SH2OForma y color:SolidPeso molecular:1224.1817R(18S)-EpETE
CAS:<p>17R(18S)-EpETE: Oxylipin, eicosapentaenoic acid metabolite, activates BKCa channels, has negative chronotropic effects.</p>Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.457Lyso-Globotriaosylceramide (d18:1)
CAS:<p>Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.</p>Fórmula:C36H67NO17Forma y color:SolidPeso molecular:785.922Cyclic ADP-ribose ammonium
<p>cADPR ammonium is a second messenger that boosts cytosolic calcium via Ryanodine receptors and TRPM2 channels.</p>Forma y color:LiquidILS-920
CAS:<p>ILS-920, a Rapamycin analog, has reduced immunosuppression, enhanced neuroprotection, and preferentially binds FKBP52 and L-type VGCC β1.</p>Fórmula:C57H86N2O14Pureza:98%Forma y color:SolidPeso molecular:1023.3Chlorocresol
CAS:<p>Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.</p>Fórmula:C7H7ClOForma y color:SolidPeso molecular:142.58PDDHV
CAS:<p>PDDHV: a capsaicin-like vanilloid selective for rat TRPV1; induces Ca2+ uptake in neurons, EC50 of 70 nM.</p>Fórmula:C49H72O11Forma y color:SolidPeso molecular:837.09Flosatidil
CAS:<p>Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,</p>Fórmula:C26H34F3N3O3SPureza:98.29% - 99.60%Forma y color:SolidPeso molecular:525.63ω-Conotoxin GVIA
CAS:<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Fórmula:C120H182N38O43S6Pureza:98%Forma y color:SolidPeso molecular:3037Mast cell degranulating peptide (28-49)
CAS:<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Fórmula:C110H196N40O24S4Pureza:98%Forma y color:SolidPeso molecular:2591.25GTx1-15
<p>GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3</p>Fórmula:C176H271N53O45S7Pureza:98%Forma y color:SolidPeso molecular:4073.82(±)5(6)-DiHETE
CAS:<p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.472sFTX-3.3
CAS:<p>sFTX-3.3 is a calcium ion channel antagonist, exhibiting IC50 values of approximately 0.24 mM and 0.70 mM against P-type and N-type channels respectively.</p>Fórmula:C12H29N7OForma y color:SolidPeso molecular:287.412
