Canal de calcio
Los canales de calcio son proteínas de membrana que regulan el flujo de iones de calcio hacia dentro y fuera de las células, lo cual es esencial para diversas funciones celulares, como la contracción muscular, la liberación de neurotransmisores y la expresión génica. La desregulación de la actividad de los canales de calcio está asociada con condiciones como la hipertensión, las arritmias cardíacas y los trastornos neurológicos. En CymitQuimica, ofrecemos una amplia selección de moduladores de canales de calcio para apoyar su investigación en salud cardiovascular, neurobiología y transducción de señales.
Se han encontrado 493 productos de "Canal de calcio"
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1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride
CAS:<p>1-(aminomethyl)cyclopropanecarboxylic acid hydrochloride inhibits L amino acid transporter proteins and the α2δ subunit of voltage-gated calcium channels.1-(</p>Fórmula:C5H10ClNO2Pureza:>99.99%Forma y color:SolidPeso molecular:151.59Calcium Channel antagonist 2
CAS:<p>Calcium Channel antagonist 2 is a calcium channel antagonist (IC50=5-20 μM) that can be used to study diseases due to Ca2+ channels like pain and diabetes.</p>Fórmula:C23H25FN2O4SPureza:99.34%Forma y color:SolidPeso molecular:444.52Lyso-Globotriaosylceramide (d18:1)
CAS:<p>Lyso-Gb3, lacking fatty acyl, binds Stx1 with cholesterol and phosphatidylcholine, not Stx2; lowers neutrophil viability; accumulates in Fabry disease.</p>Fórmula:C36H67NO17Forma y color:SolidPeso molecular:785.922Calcium Channel Compound Library
<p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>Forma y color:Odour SolidLY393615
<p>LY393615 (NCC1048) is a novel blocker of both neuronal Ca²⁺ (calcium) and Na⁺ (sodium) channels, exhibiting half-maximal inhibitory concentrations (IC₅₀) of 1.9</p>Pureza:98%Forma y color:Odour Solidγ-Glutamylserine TFA
<p>γ-Glutamylserine TFA (γ-Glu-Ser TFA) serves as a calcium receptor activator and is utilized in research focused on Parkinson's disease, diabetes, and obesity [1</p>Fórmula:C10H15F3N2O8Pureza:98%Forma y color:SoildPeso molecular:348.23Calcium Channel antagonist 5
CAS:<p>Calcium Channel antagonist5 (compound 32) is a calcium channel antagonist with a pIC50 of 5.50.</p>Fórmula:C17H18N2O6Forma y color:SolidPeso molecular:346.34ω-Agatoxin IVA
CAS:<p>Selective blocker of P-type calcium channels (IC50 < 1 - 3 nM). Also inhibits N-type channels at micromolar concentrations.</p>Fórmula:C217H360N68O60S10Pureza:98%Forma y color:SolidPeso molecular:5202.25Oxodipine
CAS:<p>Oxodipine blocks rabbit aortic contraction and weakens rat cardiac force; reduces Ca currents in myocytes; side effects: mouse constipation, dog gum swelling.</p>Fórmula:C19H21NO6Pureza:99.24%Forma y color:SolidPeso molecular:359.372-Nitrobenzoic acid
CAS:<p>2-Nitrobenzoic acid is an anti-growth agent with an IC50 of 8.3 μM against Jurkat cells with T-type Ca²⁺ channel alpha 1H/delta 25.</p>Fórmula:C7H5NO4Pureza:99.97%Forma y color:SoildPeso molecular:167.12Flosatidil
CAS:<p>Flosatidil is a small molecule voltage-gated calcium channel complex (VDCCs) blocker for the treatment of neurological disorders and cardiovascular diseases,</p>Fórmula:C26H34F3N3O3SPureza:98.29% - 99.60%Forma y color:SolidPeso molecular:525.63Candidalysin
CAS:<p>Candidalysin is a cytolytic peptide toxin initially isolated from *Candida albicans*, exhibiting both toxic and non-toxic properties. It activates epithelial cell signaling pathways by interacting with the epithelial growth factor receptor (EGFR) on host cells, leading to the activation of matrix metalloproteinases (MMP) and calcium ion influx, which results in inflammatory responses and immune cell recruitment. Additionally, Candidalysin exhibits cytotoxicity by causing membrane damage to host cells.</p>Fórmula:C153H266N38O38S2Forma y color:SolidPeso molecular:3310.11Ziconotide
CAS:<p>Ziconotide: analgesic from cone snail for severe, chronic pain; synthetic ω-conotoxin.</p>Fórmula:C102H172N36O32S7Pureza:98%Forma y color:White PowderPeso molecular:2639.13Calcium Ionophore I
CAS:<p>Calcium Ionophore I has a wide range of applications in life science related research.</p>Fórmula:C38H72N2O8Forma y color:SolidPeso molecular:685.0O-Desmethylcarvedilol
CAS:<p>O-Desmethylcarvedilol (Desmethylcarvedilol) is an active metabolite of Carvedilol, a non-selective β-adrenergic receptor (β-AR) antagonist. This compound inhibits store overload-induced calcium release in HEK293 cells expressing the RyR2 R4496C mutation (IC50= 7.62 µM). Additionally, O-Desmethylcarvedilol slows the increase in heart rate and prevents diastolic pressure reduction induced by Isoproterenol in conscious rabbits (ED50s = 32 and 5 µg/kg).</p>Fórmula:C23H24N2O4Forma y color:SolidPeso molecular:392.45ω-Conotoxin GVIA
CAS:<p>Peptide neurotoxin; selectively and reversibly blocks N-type calcium channels (IC50 = 0.15 nM). Reduces (RS)-3,5-DHPG -induced long term depression in vivo.</p>Fórmula:C120H182N38O43S6Pureza:98%Forma y color:SolidPeso molecular:3037Ryanodine
CAS:<p>Ryanodine: a diterpenoid modulating Ca2+ release via ryanodine receptors; concentration-dependent effects; found in Ryania speciosa; toxic.</p>Fórmula:C25H35NO9Pureza:98%Forma y color:White SolidPeso molecular:493.553SNX-482
CAS:<p>Potent CaV2.3 calcium channel blocker, selective, voltage-dependent, with 30 nM IC50. Offers antinociceptive effects on C and Aδ fibres.</p>Fórmula:C192H274N52O60S7Pureza:98%Forma y color:SolidPeso molecular:4495.01Mast cell degranulating peptide (28-49)
CAS:<p>Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice.</p>Fórmula:C110H196N40O24S4Pureza:98%Forma y color:SolidPeso molecular:2591.25G-Glu-Ser
CAS:<p>G-Glu-Ser is a calcium receptor activator and Flavor-enriching agent.</p>Fórmula:C8H14N2O6Forma y color:SolidPeso molecular:234.21Levamlodipine besylate Hemipentahydrate
CAS:<p>Levamlodipine besylate hemipentahydrate is the besylate hemipentahydrate salt form of Levamlodipine. It is an orally effective calcium channel blocker with antioxidative and vasodilatory properties. This compound can reduce serum malondialdehyde (MDA) levels, enhance the activity of superoxide dismutase (SOD), and alleviate oxidative stress. Levamlodipine besylate hemipentahydrate is relevant for research in vascular dementia, hypertension, and cerebrovascular diseases.</p>Fórmula:C20H25ClN2O5·C6H6O3SH2OForma y color:SolidPeso molecular:1224.18NSC156529
CAS:<p>NSC156529 suppresses AKT1, reduces cancer cell growth in vitro, and inhibits prostate tumors in vivo.</p>Fórmula:C28H21ClS2Pureza:98%Forma y color:SolidPeso molecular:457.05D-myo-Inositol-1,3-diphosphate (sodium salt)
CAS:<p>D-myo-Inositol-1,3-phosphate (Ins(1,3)P) is an inositol phosphate involved in cellular signal transduction.</p>Fórmula:C6H12Na2O12P2Forma y color:SolidPeso molecular:384.08Mipsagargin
CAS:<p>Mipsagargin (G-202) is a new antibiotic that inhibits DNA biosynthesis.</p>Fórmula:C66H100N6O27Pureza:98%Forma y color:SolidPeso molecular:1409.52NAADP tetrasodium salt
CAS:<p>Ca2+ mobilizing agent</p>Fórmula:C21H27N6O18P3Pureza:98%Forma y color:SolidPeso molecular:744.39GTx1-15
<p>GTx1-15, an inhibitor cystine knot (ICK) peptide, antagonizes the voltage-dependent calcium channel Cav3.1, as well as voltage-dependent sodium channels Nav1.3</p>Fórmula:C176H271N53O45S7Pureza:98%Forma y color:SolidPeso molecular:4073.82Ins(1,4,5)-P3 hexapotassium salt
CAS:<p>D-myo-Inositol 1,4,5-trisphosphate hexapotassium salt is promotes endoplasmic The second messenger of net calcium ions.</p>Fórmula:C6H9K6O15P3Pureza:98%Forma y color:SolidPeso molecular:648.64Triphenylethylene
CAS:<p>Compound PDK0283, with CAS No. 58-72-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0283 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>Fórmula:C20H16Forma y color:White PowderPeso molecular:256.34ProTx-I
CAS:<p>Selective blocker for CaV3.1 (IC50 = 0.2 μM), CaV3.2 (31.8 μM), also inhibits NaV1.8 and blocks KV2.1 channels.</p>Fórmula:C171H245N53O47S6Pureza:98%Forma y color:SolidPeso molecular:3987.51BTT-266
CAS:<p>BTT-266 is a blocker of voltage-gated calcium channel for pain management.</p>Fórmula:C34H28N4O4Pureza:98.34%Forma y color:SolidPeso molecular:556.61D-myo-Inositol-1,3,4,5-tetraphosphate (sodium salt)
CAS:<p>Ins(1,3,4,5)-P4, made via Ins(1,4,5)P3 phosphorylation, boosts calcium by opening ER and plasma membrane channels.</p>Fórmula:C6H8Na8O18P4Forma y color:SolidPeso molecular:675.93Elgodipine
CAS:<p>Elgodipine decreases angina severity, inhibits muscle growth, and is voltage-sensitive, showing promise for angina treatment.</p>Fórmula:C29H33FN2O6Pureza:98.95% - 99.50%Forma y color:SolidPeso molecular:524.58Calcium Channel antagonist 3
CAS:<p>Calcium Channel antagonist 3 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Fórmula:C23H26N2O4SPureza:>99.99%Forma y color:SolidPeso molecular:426.53D-myo-Inositol-1,4,5-triphosphate trisodium
CAS:<p>D-myo-Inositol-1,4,5-triphosphate trisodium (Inositol 1,4,5-trisphosphate trisodium) is a second messenger produced in cells by phospholipase C-mediated</p>Fórmula:C6H15Na3O15P3Pureza:98%Forma y color:SolidPeso molecular:489.06SB-237376
CAS:<p>SB-237376 is a calcium and potassium channel antagonist used to treat cardiac arrhythmias.</p>Fórmula:C20H25N3O5Pureza:98.88% - 99.81%Forma y color:SoildPeso molecular:387.43Ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate
CAS:<p>ethyl 4-chloro-2-oxo-1,2-dihydroquinoline-3-carboxylate inhibits NAD(P)H: quinone oxidoreductase 1.</p>Fórmula:C12H10ClNO3Pureza:99.19%Forma y color:SolidPeso molecular:251.67Chlorocresol
CAS:<p>Chlorocresol (4-Chloro-3-methylphenol) is an antiseptic medication.</p>Fórmula:C7H7ClOForma y color:SolidPeso molecular:142.58(±)5(6)-DiHETE
CAS:<p>Eicosapentaenoic acid is an ω-3 polyunsaturated fatty acid that is abundant in marine organisms and fish oils.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.472ω-Conotoxin MVIIC
CAS:<p>Peptide neurotoxin; wide spectrum blocker of N, P and Q type calcium channels.</p>Fórmula:C106H178N40O32S7Pureza:98%Forma y color:White Lyophilised SolidPeso molecular:2749ω-Agatoxin TK
CAS:<p>Selective blocker of CaV2.1 P/Q-type calcium channels.</p>Fórmula:C215H337N65O70S10Pureza:98%Forma y color:SolidPeso molecular:5273.02MRS1845
CAS:<p>MRS1845 is a selective inhibitor of store-operated calcium (SOC) channel (IC50 of 1.7 μM).</p>Fórmula:C21H22N2O6Pureza:99.69%Forma y color:SolidPeso molecular:398.41Almorexant hydrochloride
CAS:<p>Almorexant hydrochloride (ACT 078573 hydrochloride) is a dual orexin receptor antagonist that induces apoptosis and can be used to study sleep disorders.</p>Fórmula:C29H32ClF3N2O3Pureza:99.85%Forma y color:SolidPeso molecular:549.02YM-244769
CAS:<p>YM-244769 (3-Pyridinecarboxamide, N-[(3-aminophenyl)methyl]-6-[4-[(3-fluorophenyl)methoxy]phenoxy]-) is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3)</p>Fórmula:C26H22FN3O3Pureza:95.62%Forma y color:SolidPeso molecular:443.47YM-244769 dihydrochloride
CAS:<p>YM-244769 dihydrochloride is an effective inhibitor of Na+/Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM.</p>Fórmula:C26H24Cl2FN3O3Pureza:98%Forma y color:SolidPeso molecular:516.39Nicardipine-d3 hydrochloride
CAS:<p>Nicardipine D3 hydrochloride is the deuterium labeled Nicardipine hydrochloride.</p>Fórmula:C26H30ClN3O6Pureza:98%Forma y color:SolidPeso molecular:519N-Palmitoyl Glycine
CAS:<p>Acyl amides like AEA modulate pain/inflammation. PalGly, similar to N-acyl ethanolamines, inhibits nociception and induces calcium influx in cells.</p>Fórmula:C18H35NO3Forma y color:SolidPeso molecular:313.48(S)-Lercanidipine D3 hydrochloride
CAS:<p>(S)-Lercanidipine D3 hydrochloride is a deuterium labeled Lercanidipine D3 hydrochloride. (S)-Lercanidipine hydrochloride is an agent of antihypertensive.</p>Fórmula:C36H42ClN3O6Pureza:98%Forma y color:SolidPeso molecular:651.21(R)-Nicardipine
CAS:<p>(R)-Nicardipine is the less active R enantiomer of Nicardipine. Nicardipine is a blocker of calcium channel(IC50 of 1 μM for blocking cardiac calcium channels).</p>Fórmula:C26H29N3O6Forma y color:SolidPeso molecular:479.53HSK16149
CAS:<p>HSK16149 is a novel ligand of voltage-gated calcium channel (VGCC) α 2 δ subunit with analgesic activity.</p>Fórmula:C12H19NO2Forma y color:SolidPeso molecular:209.28Catharanthine
CAS:<p>Catharanthine ((+)-3,4-Didehydrocoronaridine) suppresses nicotinic receptor-mediated diaphragm contractions (IC50=59.6 μM).</p>Fórmula:C21H24N2O2Pureza:99.11%Forma y color:White PowderPeso molecular:336.43
