Canal de calcio
Los canales de calcio son proteínas de membrana que regulan el flujo de iones de calcio hacia dentro y fuera de las células, lo cual es esencial para diversas funciones celulares, como la contracción muscular, la liberación de neurotransmisores y la expresión génica. La desregulación de la actividad de los canales de calcio está asociada con condiciones como la hipertensión, las arritmias cardíacas y los trastornos neurológicos. En CymitQuimica, ofrecemos una amplia selección de moduladores de canales de calcio para apoyar su investigación en salud cardiovascular, neurobiología y transducción de señales.
Se han encontrado 541 productos de "Canal de calcio"
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IAB15
CAS:IAB15 is a potent inhibitor of T-type calcium channel that can be used in the research of epilepsy [1].Fórmula:C15H14F3NO2Forma y color:SolidPeso molecular:297.27IAA65
CAS:IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].Fórmula:C16H13F6NO2Forma y color:SolidPeso molecular:365.27Cav 3.1 blocker 1
CAS:Cav 3.1 blocker 1 (compound 12) is a T-type calcium channel inhibitor with an IC50 value of 160 nM for Cav3.1. It exhibits weaker inhibition on Cav 3.2 with an IC50 of 5000 nM and shows no inhibitory effect on Cav 3.3 and Cav 1.2 (IC50 > 10000 nM).Fórmula:C26H19F6N3O2Peso molecular:519.438Mibefradil dihydrochloride hydrate
CAS:Mibefradil dihydrochloride hydrate is a long-acting antihypertensive blocking high-voltage L calcium channels.Fórmula:C29H42Cl2FN3O4Forma y color:SolidPeso molecular:586.57Cav 2.2/3.2 blocker 1
Compound 9e is a Cav 2.2/3.2 blocker; IC50: 1.22 μM & 80 μM, respectively; penetrates CNS.Fórmula:C28H30N2O3Forma y color:SolidPeso molecular:442.55SB-423557
CAS:SB-423557 is an orally active antagonist of calcium-sensing receptor (CaR) with IC50 of 520 nMFórmula:C28H36N2O4Pureza:98%Forma y color:SolidPeso molecular:464.60(rel)-Mirogabalin
CAS:(rel)-Mirogabalin ((rel)-DS5565) is an inhibitor of voltage-dependent calcium channels, specifically targeting the α2δ-1 subunit.Fórmula:C12H19NO2Forma y color:SolidPeso molecular:209.28Mibefradil
CAS:<p>Mibefradil is a calcium channel blocker with moderate selectivity for T-type Ca2+ channels (IC50s: 2.7 μM and 18.6 μM for T-type and L-type currents).</p>Fórmula:C29H38FN3O3Pureza:98%Forma y color:SolidPeso molecular:495.63Cav 3.2 inhibitor 2
Cav 3.2 inhibitor 2 blocks T-type Ca2+ channels (IC50=0.09339 μM) and reduces mouse somatic/visceral pain. Used for intractable pain studies.Fórmula:C32H37F2N3OForma y color:SolidPeso molecular:517.65T-Type calcium channel inhibitor 2
Compound 6g inhibits T-type Ca channels (IC50: Cav3.1-31μM, Cav3.2-83μM), cytotoxic to A549 (IC50: 5μM) & HCT-116 cells (IC50: 6.4μM).Fórmula:C36H39FN4OSForma y color:SolidPeso molecular:594.78TTA-P1
CAS:TTA-P1: potent T-type calcium channel inhibitor; impacts neuron firing, hormone secretion, cell growth; potential in absence epilepsy research.Fórmula:C19H27Cl2FN2OForma y color:SolidPeso molecular:389.33BER-5
CAS:BER-5 is a potent MrgX2 antagonist, demonstrating broad-spectrum antagonistic activity against various MrgX2 agonists. It can inhibit Substance P(SP)-induced degranulation in LAD2 cells and alleviate SP-induced allergic reactions in mice. BER-5 is useful for researching mechanisms related to allergic reactions.Fórmula:C20H16O4Forma y color:SolidPeso molecular:320.34Emopamil
CAS:Emopamil, a calcium channel inhibitor, reduces neuronal damage caused by ischemia.Fórmula:C23H30N2Forma y color:SolidPeso molecular:334.5CAD204520
CAS:CAD204520 functions as an inhibitor of SERCA (IC50 = 0.34 μM), specifically targeting mutations in the wild-type NOTCH1 protein associated with T-cell acute lymphoblastic leukemia (T-ALL) and mantle cell lymphoma (MCL).Fórmula:C23H32F3N3O2Forma y color:SolidPeso molecular:439.51RWJ 22108
CAS:RWJ 22108 is a bronchial-selective calcium channel (calcium channel) blocker that exhibits an IC50 of 5.7 nM in dog bronchial smooth muscle calcium-dependent contractions.Fórmula:C27H30ClFN2O4SForma y color:SolidPeso molecular:533.06CCR4 antagonist 2
CAS:CCR4 antagonist 2 (Compound 31) is a novel potent, orally bioavailable small molecule antagonists of CC chemokine receptor 4 (CCR4) that inhibits TregFórmula:C26H28Cl2N6OPureza:98%Forma y color:SolidPeso molecular:511.45Leualacin
CAS:Leualacin is a novel calcium blocker from Hapsidospora irregularis.Fórmula:C31H47N3O7Pureza:98%Forma y color:SolidPeso molecular:573.72MP-010
CAS:<p>MP-010 is an FKBP12 ligand that regulates cytosolic calcium by stabilizing RyR channel activity. It facilitates functional improvement in SOD1G93A mice with amyotrophic lateral sclerosis (ALS), evidenced by enhanced motor coordination, increased integrity of neuromuscular junctions, and significantly higher spinal motor neuron survival rates. MP-010 is applicable for research in the field of neurological disorders.</p>Fórmula:C14H20N4O2SForma y color:SolidPeso molecular:308.399Verapamil EP Impurity C hydrochloride
CAS:NSC-609249 hydrochloride, an impurity of Verapamil, is a calcium channel blocker with potent orally active properties. It also functions as a first-generation P-glycoprotein (P-gp) inhibitor.Fórmula:C12H20ClNO2Forma y color:SolidPeso molecular:245.75(Rac)-PD0299685
CAS:<p>(Rac)-PD0299685 is a potent voltage-dependent calcium channel inhibitor for the study of retina-related diseases.</p>Fórmula:C10H21NO2Pureza:97.20%Forma y color:SolidPeso molecular:187.28
