Receptor GABA
Los receptores GABA son los principales receptores de neurotransmisores inhibitorios en el sistema nervioso central, desempeñando un papel crítico en la regulación de la excitabilidad neuronal y el mantenimiento del equilibrio entre excitación e inhibición. La disfunción de los receptores GABA está implicada en varios trastornos neurológicos y psiquiátricos, como la epilepsia, la ansiedad y la depresión. En CymitQuimica, ofrecemos una gama completa de moduladores de receptores GABA para apoyar su investigación en neurobiología, salud mental y desarrollo terapéutico.
Se han encontrado 336 productos de "Receptor GABA"
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Afizagabar
CAS:<p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>Fórmula:C19H12FN3O2SForma y color:SolidPeso molecular:365.38mGAT-IN-1
CAS:<p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>Fórmula:C28H34ClN3O2S2Forma y color:SolidPeso molecular:544.17CGP 54626 hydrochloride
CAS:<p>CGP 54626 hydrochloride is a GABAB receptor antagonist.</p>Fórmula:C18H29Cl3NO3PPureza:98%Forma y color:SolidPeso molecular:444.76Piperidine-4-sulfonic acid
CAS:<p>Piperidine-4-sulfonic acid is a potent GABA agonist, demonstrating an IC50 value of 0.034 μM for the inhibition of H-GABA binding [1].</p>Fórmula:C5H11NO3SPureza:98%Forma y color:SolidPeso molecular:165.21CGP36216 hydrochloride
CAS:<p>CGP36216 hydrochloride acts as a selective antagonist at the presynaptic GABA receptor, specifically binding to the GABAB receptor with a Ki value of 0.3 μM. This compound is leveraged in research focused on anxiety and trauma-related disorders [1] [2].</p>Fórmula:C5H15ClNO2PForma y color:SolidPeso molecular:187.6L 663581
CAS:<p>L 663581 is the benzodiazepine receptor partial agonist.</p>Fórmula:C17H16ClN5O2Pureza:98%Forma y color:SolidPeso molecular:357.796,2'-Dihydroxyflavone
CAS:<p>6,2'-Dihydroxyflavone is a novel antagonist of GABAA receptor.</p>Fórmula:C15H10O4Pureza:99.44% - 99.67%Forma y color:SolidPeso molecular:254.24NCS-382 sodium
CAS:<p>NCS-382 (sodium) is a potent antagonist of the GABA receptor, exhibiting anti-sedative and anti-hypnotic properties, with applications in neurological disease</p>Fórmula:C13H13NaO3Pureza:98%Forma y color:SolidPeso molecular:240.23TPA 023
CAS:<p>TPA 023 is a selective agonist of GABAA α2/α3 subtype (Kis = 0.19 - 0.41 nM).</p>Fórmula:C20H22FN7OPureza:99.75%Forma y color:SolidPeso molecular:395.43SCS
CAS:<p>SCS is a GABAA receptor antagonist.</p>Fórmula:C14H12N2O3Pureza:99.73%Forma y color:SolidPeso molecular:256.26L-822179
CAS:<p>L-822179 (α5IA) is a selective inverse agonist for the Α5 subtype of GABAA receptor with higher intrinsic activity at the A5 subtype than other drugs.</p>Fórmula:C17H14N8O2Pureza:98.5% - 99.61%Forma y color:SolidPeso molecular:362.35PHP 501 trifluoroacetate
CAS:<p>GABAA antagonist</p>Fórmula:C20H21N3OPureza:98%Forma y color:SolidPeso molecular:319.4GABA-IN-4
CAS:<p>GABA-IN-4 (Compound 17) is a derivative of N-(indol-3-ylglyoxylyl)benzylamine. It exhibits high affinity for the benzodiazepine receptor (BzR), the binding site within the GABAA receptor complex, with a Ki value of 67 nM. Benzodiazepines are widely used as anxiolytic, sedative-hypnotic, and anticonvulsant agents.</p>Fórmula:C17H13ClN2O2Forma y color:SolidPeso molecular:312.75Moxetomidate
CAS:<p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>Fórmula:C15H18N2O3Forma y color:SolidPeso molecular:274.315Desmethylflunitrazepam
CAS:<p>Desmethylflunitrazepam (Norflunitrazepam) is a benzodiazepine derivative and an active metabolite of Flunitrazepam.</p>Fórmula:C15H10FN3O3Forma y color:SolidPeso molecular:299.26SGE-516
CAS:<p>SGE516: neuroactive steroid, enhances GABAA, lowers neuronal activity, protects from seizures.</p>Fórmula:C23H35N3O2Pureza:98%Forma y color:SolidPeso molecular:385.54Cyproflanilide
CAS:<p>Cyproflanilide is a GABAR antagonist that exhibits high activity against a variety of pests, including those from the Lepidoptera, Coleoptera, and Thysanoptera orders.</p>Fórmula:C28H17BrF12N2O2Forma y color:SolidPeso molecular:721.33Tuclazepam
CAS:<p>Tuclazepam (KC 1956) is a derivative of the benzodiazepine class of drugs, exhibiting anti-anxiety and sedative properties.</p>Fórmula:C17H16Cl2N2OForma y color:SolidPeso molecular:335.23GABAA receptor agonist 1
<p>Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.</p>Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.45ZK 93426 hydrochloride
CAS:<p>benzodiazepine receptor antagonist,competitive</p>Fórmula:C18H21ClN2O3Pureza:98%Forma y color:SolidPeso molecular:348.82S-8510 phosphate
CAS:<p>S-8510 phosphate is an agonist of inverse Benzodiazepine (BDZ) receptor(Kis of 34.6 nM, 36.2 nM for –GABA and +GABA respectively).</p>Fórmula:C12H13N4O6PPureza:98%Forma y color:SolidPeso molecular:340.23Gabaculine HCl
CAS:<p>Gabaculine, an irreversible GABA-T inhibitor (Ki: 2.9 μM), impacts plastid development and affects DPOR/GluTR levels.</p>Fórmula:C7H10ClNO2Forma y color:SolidPeso molecular:175.61EF1502 free base
CAS:<p>EF1502 is a potent and selective GABA transporter inhibitor.</p>Fórmula:C22H26N2O2S2Pureza:98%Forma y color:SolidPeso molecular:414.58Fletazepam
CAS:<p>Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.</p>Fórmula:C17H13ClF4N2Forma y color:SolidPeso molecular:356.74BGT1-IN-1
CAS:<p>BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.</p>Fórmula:C6H9NO2Forma y color:SolidPeso molecular:127.14GABAA receptor agonist 2
<p>Compound 4c, a potent GABAA agonist with anti-depressive effects in mouse FST/TST, shows promise in depression research.</p>Fórmula:C22H36O5Forma y color:SolidPeso molecular:380.52TP003
CAS:<p>TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.</p>Fórmula:C23H16F3N3OPureza:99.17%Forma y color:SolidPeso molecular:407.39(-)-Bicuculline methobromide
CAS:<p>(-)-Bicuculline methobromide is a potent antagonist of GABAA receptor .</p>Fórmula:C21H20BrNO6Forma y color:WhitePeso molecular:462.292-AEMP TFA
CAS:<p>2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.</p>Fórmula:C3H10NO3PPureza:98%Forma y color:SolidPeso molecular:139.0913-Methylglutaconic acid
CAS:<p>3-Methylglutaconic acid, a primary metabolite accumulating in 3-Methylglutaconic aciduria (MGTA), induces lipid and protein oxidation, while diminishing non-enzymatic antioxidant defenses in cerebral cortex supernatants, thereby promoting oxidative stress in the cerebral cortex. This compound is utilized in research concerning brain damage diseases [1].</p>Fórmula:C6H8O4Pureza:98%Forma y color:SolidPeso molecular:144.13Alfadolone acetate
CAS:<p>Alfadolone acetate is a gamma-aminobutyric acid (GABA) receptor agonist.</p>Fórmula:C23H34O5Forma y color:SolidPeso molecular:390.51Pazinaclone
CAS:<p>Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.</p>Fórmula:C25H23ClN4O4Pureza:97.79% - 99.07%Forma y color:SolidPeso molecular:478.93CGP 44532
CAS:<p>CGP 44532 a GABAB receptor agonist.</p>Fórmula:C4H12NO3PPureza:98%Forma y color:SolidPeso molecular:153.12Pipequaline
CAS:<p>Pipequaline (PK-8165) is an anticonflict & anticonvulsant quinoline derivative. It is an anxiolytic drug that was never marketed. It possesses a novel chemical structure that is not closely related to other drugs of this type. The drug has a similar pharmacological profile to the benzodiazepine family of drugs, but with mainly anxiolytic properties and very little sedative, amnestic or anticonvulsant effects, and so is classified as a nonbenzodiazepine anxiolytic.</p>Fórmula:C22H24N2Pureza:98%Forma y color:SolidPeso molecular:316.44Ref: TM-T4655
Producto descatalogadoXilmenolone
CAS:<p>Xilmenolone acts as a positive allosteric modulator of the GABA_A receptor [1].</p>Fórmula:C26H37N3O2Pureza:98%Forma y color:SolidPeso molecular:423.59Ref: TM-T78670
Producto descatalogadoCGP 56999A
CAS:<p>CGP 56999A is a GABA(B) receptor antagonist; it boosts BDNF and reduces dopamine loss in rat striatum.</p>Fórmula:C19H30NO5PPureza:98%Forma y color:SolidPeso molecular:383.42
