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Metabolismo

Metabolismo

Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.

Subcategorías de "Metabolismo"

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Se han encontrado 8597 productos de "Metabolismo"

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  • Arachidonoyl-N-methyl amide
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    Arachidonoyl-N-methyl amide

    CAS:
    <p>Anandamide (AEA), an endogenous cannabinoid, interacts with both central (CB1) and peripheral (CB2) cannabinoid receptors. Its effects are concluded through the cellular uptake and enzymatic breakdown of its amide bond by fatty acid amide hydrolase. Arachidonoyl-N-methyl amide, an analog of anandamide, specifically targets the human CB1 receptor, displaying a binding affinity with a Ki of 60 nM. It completely inhibits rat glial gap junction intercellular communication at a concentration of 50 µM.</p>
    Fórmula:C21H35NO
    Forma y color:Solid
    Peso molecular:317.5

    Ref: TM-T84534

  • cis-8-Octadecenoic Acid
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    cis-8-Octadecenoic Acid

    CAS:
    <p>Cis-8-Octadecenoic acid, a monounsaturated fatty acid and isomer of oleic acid, trans-vaccenic acid, trans-petroselinic acid, and cis-petroselinic acid, is present in partially hydrogenated vegetable oil and milk fat.</p>
    Fórmula:C18H34O2
    Forma y color:Solid
    Peso molecular:282.46

    Ref: TM-T85122

  • GIV3727
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    GIV3727

    CAS:
    <p>GIV3727, a bitter taste receptor hTAS2R antagonist, inhibits the activation of hTAS2R31 by saccharin and acesulfame potassium, effectively diminishing the</p>
    Fórmula:C12H22O2
    Forma y color:Solid
    Peso molecular:198.3

    Ref: TM-T82315

  • (R)-IDO/TDO-IN-1
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    (R)-IDO/TDO-IN-1

    CAS:
    <p>(R)-IDO/TDO-IN-1 (compound 25), an indoleamine-2,3-dioxygenase (IDO) inhibitor, demonstrates good pharmacokinetic properties and exerts anti-tumor effects in the MC38 xenograft model. This compound exhibits synergy when combined with the anti-PD-1 monoclonal antibody (SHR-1210) [1].</p>
    Fórmula:C25H24FN5
    Forma y color:Solid
    Peso molecular:413.49

    Ref: TM-T84728

  • Biliverdin
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    Biliverdin

    CAS:
    <p>Biliverdin, produced through the oxidation of bilirubin, can also be synthesized through a non-protoporphyrin pathway in Corynebacterium glutamicum [1].</p>
    Fórmula:C33H34N4O6
    Forma y color:Solid
    Peso molecular:582.65

    Ref: TM-T84736

  • ICMT-IN-21
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    ICMT-IN-21

    CAS:
    <p>ICMT-IN-21 (compound 6ag) is an ICMT inhibitor with an IC50 value of 8.8 µM, featuring sulfonamide-modified farnesyl cysteine (SMFC).</p>
    Fórmula:C22H33NO4S3
    Forma y color:Solid
    Peso molecular:471.7

    Ref: TM-T82123

  • Clocortolone pivalate
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    Clocortolone pivalate

    CAS:
    <p>Clocortolone pivalate, a synthetic steroid, treats dermatitis and psoriasis.</p>
    Fórmula:C27H36ClFO5
    Forma y color:Solid
    Peso molecular:495.02

    Ref: TM-T72391

  • LB-60-OF61
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    LB-60-OF61

    CAS:
    <p>LB-60-OF61 is a NAMPT inhibitor, a NAMPT inhibitor that displays antiproliferative activity against MYC oncogene-dependent cancer cell lines.</p>
    Fórmula:C29H30N6O2
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:494.59

    Ref: TM-T11823

  • ML395
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    ML395

    CAS:
    <p>ML395 is a potent, selective PLD2 allosteric inhibitor with potent antiviral activity (IC50 =360 nM).</p>
    Fórmula:C26H29N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:443.54

    Ref: TM-T28071

  • Amb123203
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    Amb123203

    CAS:
    <p>Amb123203 is an inhibitor of the budding of mVP40 and eVP40 VLPs that acts by blocking mVP40-795 Nedd4 protein-protein interaction.</p>
    Fórmula:C25H27N5OS
    Forma y color:Solid
    Peso molecular:445.58

    Ref: TM-T23714

  • FXa-IN-1
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    FXa-IN-1

    CAS:
    <p>FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.</p>
    Fórmula:C24H18F5N5O
    Forma y color:Solid
    Peso molecular:487.42

    Ref: TM-T63239

  • DPM-1001 trihydrochloride
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    DPM-1001 trihydrochloride

    <p>DPM-1001 trihydrochloride: Potent PTP1B inhibitor, IC50 100 nM, oral, non-competitive, anti-diabetic.</p>
    Fórmula:C35H60Cl3N3O3
    Forma y color:Solid
    Peso molecular:677.23

    Ref: TM-T72216

  • α-Glucosidase-IN-11
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    α-Glucosidase-IN-11

    CAS:
    <p>α-Glucosidase-IN-11 is a highly permeable competitive inhibitor of α-glucosidase (IC50: 0.56 μM).</p>
    Fórmula:C23H20N2O6
    Forma y color:Solid
    Peso molecular:420.41

    Ref: TM-T62222

  • H-0104 Dihydrochloride
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    H-0104 Dihydrochloride

    CAS:
    <p>H-0104 Dihydrochloride is an inhibitor of ROCK that acts by applying potent intraocular pressure (IOP)-lowering effects into the eyes of monkeys.</p>
    Fórmula:C15H20BrCl2N3O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:457.21

    Ref: TM-T25482

  • Bemfivastatin hemicalcium
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    Bemfivastatin hemicalcium

    CAS:
    <p>Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.</p>
    Fórmula:C34H36FN2O6Ca
    Forma y color:Solid
    Peso molecular:607.67

    Ref: TM-T82900

  • sPLA2 inhibitor 1
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    sPLA2 inhibitor 1

    CAS:
    <p>KH064 is a sPLA2-IIA inhibitor of oral activity.</p>
    Fórmula:C31H37NO4
    Forma y color:Solid
    Peso molecular:487.63

    Ref: TM-T27731

  • M5N36
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    M5N36

    CAS:
    <p>M5N36: selective Cdc25C inhibitor, IC50: 0.15µM A, 0.19µM B, 0.06µM C; halts cell growth, boosts p-CDK1/2.</p>
    Fórmula:C20H16ClN5O3
    Forma y color:Solid
    Peso molecular:409.83

    Ref: TM-T73526

  • Iomazenil
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    Iomazenil

    CAS:
    <p>Iomazenil is an antagonist and partial inverse agonist of benzodiazepine and potential therapy for alcohol abuse.</p>
    Fórmula:C15H14IN3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:411.19

    Ref: TM-T25537

  • A 62198
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    A 62198

    CAS:
    <p>A 62198 is a potent and selective renin inhibitor with potential as a hypotensive agent.</p>
    Fórmula:C30H44N8O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:596.72

    Ref: TM-T26426

  • NUCC-0223619
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    NUCC-0223619

    CAS:
    <p>NUCC-0223619 is an IDO1 inhibitor that induces the degradation of IDO protein and can be involved in the synthesis of PROTAC.</p>
    Fórmula:C24H24ClFN2O2
    Forma y color:Solid
    Peso molecular:426.91

    Ref: TM-T62326