Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(177 productos)
- Caseína quinasa(130 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(267 productos)
- FAAH(63 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(32 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(53 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(32 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(96 productos)
- Lípido(59 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8595 productos de "Metabolismo"
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Complex III-IN-1
<p>Complex III-IN-1 inhibits complex III, has antifungal properties, and an EC50 of 18.53 mg/L against S. sclerotiorum.</p>Fórmula:C14H20ClNO2S2Forma y color:SolidPeso molecular:333.95-Carboxy-2′-deoxycytidine
CAS:<p>5-Carboxy-2′-deoxycytidine is a metabolite of Trifluridine.</p>Fórmula:C10H13N3O6Forma y color:SolidPeso molecular:271.227FTI 276 TFA
CAS:<p>FTI 276 TFA targets plasmodium falciparum & humans, inhibits PFT with IC50s: 0.9 nM (parasite) & 0.5 nM (human).</p>Fórmula:C23H28F3N3O5S2Forma y color:SolidPeso molecular:547.61TMX-4113
<p>TMX-4113 has potential to be used in cancer that is a phosphodiesterase 6D(PDE6D) and casein kinase 1α(CK1α) degrader [1].</p>Fórmula:C12H12N4O2S2Forma y color:SolidPeso molecular:308.38(S)-CPP sodium
CAS:<p>(S)-CPP sodium serves as an inhibitor of the branched-chain α-keto acid dehydrogenase complex (BCKDC) kinase, commonly referred to as BDK or keto acid dehydrogenase kinase. As a negative regulator of BCKDC activity, (S)-CPP (IC50 of 6.3 μM) inhibits BDK, which activates the complex, leading to a significant reduction in the levels of leucine/isoleucine and valine in the plasma of wild-type mice.</p>Fórmula:C9H8ClNaO2Forma y color:SolidPeso molecular:206.60FAAH/MAGL-IN-3
<p>FAAH/MAGL-IN-3 irreversibly inhibits FAAH (IC50: 179 nM) & MAGL (IC50: 759 nM) with low PAMPA permeability.</p>Fórmula:C21H25N3O6SForma y color:SolidPeso molecular:447.5CK1δ-IN-3
CAS:<p>CK1δ-IN-3 (compound 376) is a CK1δ (casein kinase 1δ) inhibitor that can be used to study neurodegenerative diseases such as Alzheimer's disease.</p>Fórmula:C24H19N3O2SPureza:99.27%Forma y color:SolidPeso molecular:413.49OMDM169
CAS:<p>OMDM169: potent/selective MAGL inhibitor, raises 2-AG, analgesic via cannabinoid receptors, IC50: 0.13-0.41μM in rat/COS-7, inactive at CB1/CB2.</p>Fórmula:C25H45NO5Pureza:98%Forma y color:SolidPeso molecular:439.63AChE/hCA I-IN-1
CAS:<p>AChE/hCA I-IN-1 (Compound L3) is an inhibitor of acetylcholinesterase (AChE) and carbonic anhydrase (CA), effectively inhibiting AChE, hCA I, and hCA II with IC50 values of 302 nM, 265 nM, and 283 nM, respectively.</p>Fórmula:C13H9BrNNaO4SForma y color:SolidPeso molecular:378.174CAII-IN-2
<p>CAII-IN-2 (3g): potent, selective CA-II inhibitor; IC50-12.1 μM for bovine CA-II; valuable in CA-related disorder research.</p>Fórmula:C18H19BrN4SForma y color:SolidPeso molecular:403.34Raloxifene N-Oxide
CAS:<p>Raloxifene N-Oxide is a Raloxifene oxidative degradation product.</p>Fórmula:C28H27NO5SPureza:98%Forma y color:SolidPeso molecular:489.58BAY-179
CAS:<p>BAY-179 is a potent, selective, species cross-reactive complex I inhibitor for the study of cancer.</p>Fórmula:C23H21N5OSPureza:98.29%Forma y color:SolidPeso molecular:415.51MRS4458
CAS:<p>MRS4458 is an effective inhibitor of the P2Y14 Receptor.</p>Fórmula:C24H20F3N5O3SPureza:98%Forma y color:SolidPeso molecular:515.51Buspirone N-oxide
CAS:<p>Buspirone N-oxide (Bu N-oxide) is a metabolite of Buspirone. Buspirone is an orally active 5-HT1A receptor agonist and a dopamine D2 (dopamine D2) autoreceptor antagonist. It is an anxiolytic agent used for research in generalized anxiety disorder.</p>Fórmula:C21H31N5O3Forma y color:SolidPeso molecular:401.503E234G HYPE-IN-1
CAS:<p>Compound I2.10 (E234G HYPE-IN-1) functions as an AMPylase inhibitor and exhibits low cytotoxicity toward human cell lines [1].</p>Fórmula:C14H9N5O2Forma y color:SolidPeso molecular:279.25Nampt activator-4
CAS:<p>Nampt activator-4, a positive allosteric modulator (N-PAM) of nicotinamide phosphoribosyltransferase (NAMPT), has an EC50 of 0.058 μM and can enhance nicotinamide adenine dinucleotide (NAD+) levels in cells [1].</p>Fórmula:C26H22F3N7OSForma y color:SolidPeso molecular:537.56BMS-214662 mesylate
CAS:<p>BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research.</p>Fórmula:C26H27N5O5S3Forma y color:SolidPeso molecular:585.718AXKO-0046
<p>AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.</p>Fórmula:C25H33N3Forma y color:SolidPeso molecular:375.55GC-IN-2
CAS:<p>GC-IN-2 (Compound 25) is an effective and selective non-sugar-based glucocerebrosidase inhibitor with an IC50 value of 6.46 μM. It is utilized in research related to Gaucher's disease.</p>Fórmula:C19H16N2O3SForma y color:SolidPeso molecular:352.41GGACK
CAS:<p>GGACK (H-Glu-Gly-Arg-CMK) is an irreversible substrate-like inhibitor of the serine protease urokinase-type plasminogen activator (uPA).</p>Fórmula:C14H25ClN6O5Peso molecular:392.84MDL-100240
CAS:<p>MDL-100240 inhibits ACE/neprilysin, effective against hypertension-induced heart/vascular changes.</p>Fórmula:C26H28N2O5SPureza:98%Forma y color:SolidPeso molecular:480.584-MDM
CAS:<p>4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the aminopeptidase activity of leukotriene A4 hydrolase (LTA4H). By promoting the degradation of proline-glycine-proline by LTA4H, 4-MDM reduces neutrophil recruitment in the lungs, alleviating inflammation without affecting the epoxide hydrolase activity of LTA4H. This compound is useful for research in pulmonary diseases.</p>Fórmula:C14H14OForma y color:SolidPeso molecular:198.26Gcase activator 2
CAS:<p>Gcase activator 2 is a β-glucocerebrosidase activator that induces dimerization of GCase, increases lysosomal substrate metabolism.</p>Fórmula:C21H24N4O2Pureza:99.51% - 99.76%Forma y color:SolidPeso molecular:364.44ABHD antagonist 1
CAS:<p>ABHD antagonist 1 is an inhibitor of ABHD6 (α/β-Hydrolase domain containing 6), involved in modulating biochemical pathways affected by ABHD6, thereby influencing cell function and inflammatory responses. This compound is applicable for research in fields such as pain, neurological disorders, inflammatory diseases, autoimmune diseases, metabolic disorders, and cancer.</p>Fórmula:C19H20BrN3O3SForma y color:SolidPeso molecular:450.35PDHK-IN-4
<p>PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.</p>Fórmula:C24H25N5O3Forma y color:SolidPeso molecular:431.49Lapaquistat
CAS:<p>Lapaquistat: active TAK-475 metabolite; reduces cholesterol synthesis and statin myotoxicity.</p>Fórmula:C31H39ClN2O8Pureza:98%Forma y color:SolidPeso molecular:603.1Lp(a)-IN-5
CAS:<p>Lp(a)-IN-5 (Compound A) is an orally active inhibitor of lipoprotein (a) [Lp(a)]. It effectively inhibits the assembly of Apo(a) and ApoB proteins, with an IC50 value of 0.41 nM. Lp(a)-IN-5 shows potential for research into diseases associated with elevated plasma Lp(a) levels, such as cardiovascular diseases.</p>Fórmula:C43H56N4O7Forma y color:SolidPeso molecular:740.927Lp-PLA2-IN-6
CAS:<p>Lp-PLA2-IN-6: Potent tetracyclic inhibitor of rhLp-PLA2, with pIC50 of 10.0, and potential in neurodegenerative research.</p>Fórmula:C25H21F5N4O3Forma y color:SolidPeso molecular:520.45NSC 828467
<p>NSC 828467 is one of the top five CA-IX inhibitors with significant in vitro anticancer activity (IC50: 27.2 nM).</p>Fórmula:C21H19N9O2SForma y color:SolidPeso molecular:461.5hCAI/II/XII-IN-1
CAS:<p>hCAI/II/XII-IN-1 (compound 7) is an inhibitor of human carbonic anhydrases hCAI, hCAII, and hCAXII, with Ki values of 78.5 nM, 9.1 nM, 605 nM, 7.7 nM, and 3.7 nM.</p>Fórmula:C12H12N2O2SForma y color:SolidPeso molecular:248.301Darlifarnib
CAS:<p>Darlifarnib (Compound (S)-058) is an inhibitor of farnesyl transferase and geranylgeranyltransferase, with IC50 values of ≤ 10 nM and > 1000 nM, respectively. It exhibits high metabolic stability in human and mouse liver microsomes, with a half-life of over 100 minutes.</p>Fórmula:C29H20N6OForma y color:SolidPeso molecular:468.509Lufironil
CAS:<p>Lufironil (HOE 077) is an inhibitor of prolyl 4-hydroxylase, designed for investigating chronic liver conditions such as alcoholic hepatitis and cirrhosis.</p>Fórmula:C13H19N3O4Forma y color:SolidPeso molecular:281.31L-690330 hydrate
<p>L-690330 hydrate inhibits IMPase; Ki: 0.30 μM (human), 0.42 μM (bovine cortex); 0.27 μM (recom. human), 0.19 μM (bovine).</p>Fórmula:C8H14O9P2Forma y color:SolidPeso molecular:316.147-APB hydrochloride
CAS:<p>7-APB hydrochloride is a benzofuran compound and serves as a metabolite of 7-MAPB.</p>Fórmula:C11H14ClNOForma y color:SolidPeso molecular:211.6889(S)-HETE
CAS:<p>9(S)-HETE is an enantiomer of (±)9-HETE, not an enzymatic product, and doesn't promote cell adhesion like 12(S)-HETE. Identified by chiral HPLC.</p>Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.47Antidiabetic agent 5
CAS:<p>Compound S1 (antidiabetic agent 5) is an antidiabetic agent that effectively inhibits the enzymes α-glucosidase and α-amylase, demonstrating IC50 values of 3.91 µM and 8.89 µM, respectively. It reduces sugar levels and holds potential for type-II diabetes research [1].</p>Fórmula:C17H15N3O4SForma y color:SolidPeso molecular:357.3820-HEDE
CAS:<p>20-HEDE (WIT 002) is a 20-hydroxyeicosatetraenoic acid (20-HETE) antagonist.</p>Fórmula:C20H36O3Pureza:98%Forma y color:SolidPeso molecular:324.50RORγt inhibitor 2
CAS:<p>RORγt Inhibitor 2, a potent inhibitor of RORγt, exhibits an IC50 of 9.2 nM and is utilized in the study of cancer, inflammation, or autoimmune diseases that are</p>Fórmula:C31H33F5N2O7SForma y color:SolidPeso molecular:672.66PDE4-IN-5
<p>PDE4-IN-5: potent PDE4 inhibitor, IC50 = 3.1 nM, superb skin penetration, anti-psoriasis effect.</p>Fórmula:C21H28N2O3Forma y color:SolidPeso molecular:356.46Casein kinase 1δ-IN-26
CAS:<p>Casein kinase1δ-IN-26 (compound 505) is a potent inhibitor of casein kinase 1δ. This compound is applicable in research related to neurodegenerative disorders such as Alzheimer’s disease.</p>Fórmula:C16H13N3O4SForma y color:SolidPeso molecular:343.357Etamicastat
CAS:<p>Etamicastat can be used in the research of cardiovascular diseases.</p>Fórmula:C14H15F2N3OSPureza:98%Forma y color:SolidPeso molecular:311.35Casein Kinase II Inhibitor IV Hydrochloride
CAS:<p>Casein Kinase II Inhibitor IV HCl promotes keratinocyte differentiation, potential for skin disorder therapy.</p>Fórmula:C24H24ClN5O3Pureza:98%Forma y color:SolidPeso molecular:465.93Anticancer agent 143
CAS:<p>Anticancer Agent 143 (Compound 369), a potent dual inhibitor targeting PTPN2 and PTP1B, exhibits IC50 values below 2.5 nM.</p>Fórmula:C19H15BrF2N3O6PS2Pureza:98%Forma y color:SolidPeso molecular:594.34Zaragozic acid C
CAS:<p>Zaragozic acid C is an effective inhibitor of squalene synthase.</p>Fórmula:C40H50O14Pureza:98%Forma y color:SolidPeso molecular:754.82(Rac)-8-Hydroxy-efavirenz
CAS:<p>(Rac)-8-Hydroxy-efavirenz is a metabolite of Efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI) used in the treatment of HIV-1.</p>Fórmula:C14H9ClF3NO3Forma y color:SolidPeso molecular:331.674GJG057
CAS:<p>GJG057 is a highly efficient and selective Leukotriene C4 synthase (LTC4S) inhibitor with an IC50 of 44 nM in human whole blood LTC4 release assays and oral activity. It demonstrates anti-inflammatory efficacy in a mouse asthma exacerbation model and can be used for the treatment of allergic inflammation.</p>Fórmula:C21H21F5N4O2Pureza:99.8%Forma y color:SolidPeso molecular:456.414-Hexen-3-one
CAS:<p>4-Hexen-3-one inhibits the growth of H. pylori in the ATCC 43526 strain and TDR strain. Additionally, this compound suppresses urease activity.</p>Fórmula:C6H10OForma y color:SolidPeso molecular:98.14(+)-Potassium Ds-threo-isocitrate monobasic
CAS:<p>(+)-Potassium Ds-threo-isocitrate monobasic is a bioactive compound known for its role in enhancing cellular metabolism and regulating energy production. This substance is also utilized in researching metabolic pathways and the regulation of enzyme activities. Widely applied in biochemical research, (+)-Potassium Ds-threo-isocitrate monobasic is studied for its potential functions in cellular processes and disease mechanisms.</p>Fórmula:C6H7KO7Forma y color:SolidPeso molecular:230.21TAK-915
CAS:<p>TAK-915: potent, brain-ready PDE2A inhibitor, 0.61 nM IC50, 4100x selectivity over PDE1A.</p>Fórmula:C19H18F4N4O5Pureza:98%Forma y color:SolidPeso molecular:458.36Utibaprilat
CAS:<p>Utibaprilat is the primary degradation product of Utibapril and functions as an ACE inhibitor.</p>Fórmula:C20H27N3O5SForma y color:SolidPeso molecular:421.51
