Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(177 productos)
- Caseína quinasa(130 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(267 productos)
- FAAH(63 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(32 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(53 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(32 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(96 productos)
- Lípido(59 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(165 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8597 productos de "Metabolismo"
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(±)18-HETE
CAS:<p>(±)18-HETE (18-Hydroxyeicosatetraenoic acid) is an arachidonic acid metabolite with a hydroxyl group on carbon 18, catalyzed by cytochrome P-450.</p>Fórmula:C20H32O3Forma y color:SolidPeso molecular:320.47O-Demethyl Lenvatinib
CAS:<p>O-Demethyl Lenvatinib, a Lenvatinib metabolite, is an oral TKI targeting VEGFR, FGFR, PDGFR, KIT & RET with potent antitumor effects.</p>Fórmula:C20H17ClN4O4Forma y color:SolidPeso molecular:412.83Atorvastatin Epoxy Tetrahydrofuran Impurity
CAS:<p>Atorvastatin Epoxy Tetrahydrofuran: an impurity from Atorvastatin oxidation; it's an oral HMG-CoA reductase inhibitor.</p>Fórmula:C26H24FNO5Pureza:98%Forma y color:SolidPeso molecular:449.47FXR antagonist 2
CAS:<p>Compound A-26, a diarylamide FXR blocker, may aid hyperlipidemia and diabetes type 2 research.</p>Fórmula:C22H26Cl2N2O2Forma y color:SolidPeso molecular:421.36α-Lactose hydrate
CAS:<p>α-Lactose (hydrate) (α-D-Lactose (hydrate)), the main carbohydrate in mammalian milk, comprises two sugar units: glucose and galactose, and occurs as two</p>Fórmula:C12H24O12Forma y color:SolidPeso molecular:360.31DSPE-PEG2000-CREKA
<p>DSPE-PEG3000-CREKA is a PEG compound composed of DSPE and the fibrin-targeting peptide (CREKA). The CREKA peptide targets tumor cells and tumor vasculature, exhibiting antitumor activity. DSPE-PEG3000-CREKA is useful in drug delivery applications.</p>Forma y color:Odour SolidC17 Sphingomyelin (d18:1/17:0)
CAS:<p>C17 Sphingomyelin is a synthetic derivative of sphingomyelin that has been used as an internal standard for the quantification of sphingomyelin.</p>Fórmula:C40H81N2O6PForma y color:SolidPeso molecular:717.05(±)-CBCQ
CAS:<p>(±)-CBCQ, an oxidation product of cannabidiol, exhibits an EC50 value of 14.7 μM for the activation of peroxisome proliferator-activated receptor γ (PPAR-γ).</p>Fórmula:C21H28O3Forma y color:SolidPeso molecular:328.458-iso Prostaglandin A1
CAS:<p>8-iso PGA1: an isoprostane, non-COX prostanoid, minor PGE1 impurity, biological effects unstudied.</p>Fórmula:C20H32O4Forma y color:SolidPeso molecular:336.472Orotidine 5′-monophosphate
CAS:<p>Orotidine 5′-monophosphate, a pyrimidine ribonucleoside, functions as an endogenous metabolite in human, E.</p>Fórmula:C10H13N2O11PForma y color:SolidPeso molecular:368.1912H-Cho-Arg (trifluoroacetate salt)
CAS:<p>2H-Cho-Arg, a cationic lipid, enables gene delivery into cells and shows cytotoxicity at 92.7 μg/ml.</p>Fórmula:C43H73F6N5O7Forma y color:SolidPeso molecular:886.06human TDO2-IN-1
<p>Human TDO2-IN-1 (Cpd-2) is a potent inhibitor of human TDO2, with an IC50 of 14.8 nM. It plays a significant role in studies related to metabolism, inflammation, and tumor immune surveillance.</p>Fórmula:C30H36N4O5Forma y color:SolidPeso molecular:532.631EN3356
CAS:<p>EN3356 is an orally available and selective inhibitor of steroidal 17-alpha-hydroxylase/C17,20 cleavage enzyme (CYP17A1 or CYP17), a non-steroidal cleavage</p>Fórmula:C16H13FN2OSPureza:97.47%Forma y color:SoildPeso molecular:300.35Clocortolone
CAS:<p>Clocortolone, a medium-strength corticosteroid, treats dermatitis as a cream ester called clocortolone pivalate.</p>Fórmula:C22H28ClFO4Pureza:98%Forma y color:SolidPeso molecular:410.91TPH1-IN-1
<p>TPH1-IN-1 (compound 40) is a xanthine derivative that serves as an inhibitor of tryptophan hydroxylase TPH1, with an IC50 of 110.1 nM.</p>Fórmula:C21H18N6O4SForma y color:SolidPeso molecular:450.47Uridine 5'-triphosphate tris salt
CAS:<p>Uridine 5'-triphosphate tris salt is an endogenous metabolite .</p>Fórmula:C13H26N3O18P3Forma y color:SolidPeso molecular:605.284-hydroxy Nonenal Mercapturic Acid
CAS:<p>Peroxidation of ω-6 PUFAs produces 4-HNE, which is rapidly cleared and excreted, mostly as urine metabolites, within 48h in rats.</p>Fórmula:C14H25NO5SForma y color:SolidPeso molecular:319.42Di-O-demethylcurcumin
CAS:<p>Di-O-demethylcurcumin (Bisdemethylcurcumin) is an intestinal metabolite of curcumin known for its neuroprotective properties.</p>Fórmula:C19H16O6Forma y color:SolidPeso molecular:340.33ARL67156 triethylamine
<p>ARL67156, a selective ecto-ATPase inhibitor, blocks NTPDase1, 3, and NPP1; used in calcific valve, asthma research. Ki: 11-18 μM.</p>Fórmula:C15H24Br2N5O12P3·3C6H15N)Forma y color:SolidPeso molecular:1154.23YYLLVR
CAS:<p>YYLLVR is an inhibitory peptide of angiotensin-converting enzyme (ACE) with an inhibition rate of 89.10%. It demonstrates a low binding energy to ACE at -35.98 kcal/mol. YYLLVR can be utilized in hypertension research.</p>Fórmula:C41H63N9O9Forma y color:SolidPeso molecular:825.99Spirolaxine
CAS:<p>Spirolaxine from Sporotrichum laxum shows anti-Helicobacter pylori activity.</p>Fórmula:C23H32O6Pureza:98%Forma y color:SolidPeso molecular:404.5N-Acetyl-α-D-glucosamine 1-phosphate disodium
CAS:<p>N-Acetyl-α-D-glucosamine 1-phosphate disodium (GlcNAc-1-P), an anomeric sugar phosphate, plays a crucial role as an intermediate in the biosynthesis of N-linked</p>Fórmula:C8H15NNaO9PForma y color:SolidPeso molecular:323.17α-Glucosidase-IN-48
<p>α-Glucosidase-IN-48 (compound 9) is a potent inhibitor of α-Glucosidase, with an IC50 of 1.30 μM.</p>Fórmula:C15H9Cl2N5O3SPeso molecular:408.98032Febuxostat sec-butoxy acid
CAS:<p>Febuxostat sec-butoxy acid is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C16H16N2O3SForma y color:SolidPeso molecular:316.37Inostamycin A
CAS:<p>Inostamycin A, a anticancer bacterial metabolite isolated from Streptomyces, is a selective inhibitor of CDP-diacylglycerol:inositol 3-phosphatidyltransferase.</p>Fórmula:C38H68O11Forma y color:SolidPeso molecular:700.94α-Amylase/α-Glucosidase-IN-4
<p>α-Amylase/α-Glucosidase-IN-4 (compound 5), a dual inhibitor targeting α-amylase (Amylases) and α-glucosidase (Glucosidase), exhibits potent inhibition with IC50</p>Fórmula:C32H26N6O10Pureza:98%Forma y color:SolidPeso molecular:654.58Cellohexaose
CAS:<p>Cellohexaose, a cellulose-derived polymer, comprises at least two β(1-4) linked D-glucose units.</p>Fórmula:C36H62O31Forma y color:SolidPeso molecular:990.86HIF-1 inhibitor-5
<p>HIF-1 inhibitor-5 (Compound 16e) is a potent inhibitor of HIF-1, exhibiting an IC50 value of 2.38 μM and demonstrating significant anti-angiogenic potential [1</p>Fórmula:C28H35NO5Forma y color:SolidPeso molecular:465.58Geranyl pyrophosphate triammonium
CAS:<p>Geranyl pyrophosphate, an intermediary for making cholesterol, terpenes, and others, forms from dimethylallyl and isopentenyl pyrophosphates.</p>Fórmula:C10H29N3O7P2Forma y color:SolidPeso molecular:365.304PPARγ agonist 15
<p>PPARγ agonist15 (Compound 7c) functions as an agonist of PPARγ, inhibiting the expression of α-amylase (HPA) and α-glucosidase (HLAG) with IC50 values of 28.35 µM and 26.21 µM, respectively. It enhances glucose uptake in L6 myotubes and improves glucose homeostasis, insulin sensitivity, and lipid metabolism in a rat model of Streptozotocin-induced diabetes.</p>Fórmula:C21H16N4O3S2Forma y color:SolidPeso molecular:436.51RORγ inverse agonist 1
CAS:<p>RORγ inverse agonist 1 has anti-inflammatory activity and can be used to treat rheumatism and psoriasis.</p>Fórmula:C22H20F3N3O3SPureza:99.68%Forma y color:SolidPeso molecular:463.47Z-Pro-prolinal
CAS:<p>Z-Pro-prolinal, an orally active PREP inhibitor, IC50: 0.4 nM in porcine.</p>Fórmula:C18H22N2O4Forma y color:SolidPeso molecular:330.38FXR agonist 10
<p>FXR agonist10 (Compound 27) acts as an agonist for FXR with an EC50 of 14.26 μM. It increases the expression of SHP and BSEP proteins while decreasing the expression of NTCP and CYP7A1 proteins. Additionally, FXR agonist10 has been shown to ameliorate ANIT-induced cholestasis in mouse models.</p>Fórmula:C15H22O4Forma y color:SolidPeso molecular:266.335-Methoxyresorcinol
CAS:<p>5-Methoxyresorcinol (Flamenol) is a chemical intermediate.</p>Fórmula:C7H8O3Pureza:95.16%Forma y color:SolidPeso molecular:140.1411-epi-Chaetomugilin I
CAS:<p>11-epi-Chaetomugilin I, from Chaetomium globosum, has cytotoxic effects against P388, HL-60, L1210 leukemia, and KB carcinoma cells.</p>Fórmula:C22H27ClO5Forma y color:SolidPeso molecular:406.9(3R,5R)-Octahydrocurcumin
CAS:<p>(3R,5R)-Octahydrocurcumin (Compound 7) is a metabolite of Curcumin produced by gut microbiota. It exhibits neuroprotective effects against Aβ25-35-induced cell damage in SH-SY5Y cells and possesses anti-inflammatory properties in LPS-stimulated BV-2 mouse microglia.</p>Fórmula:C21H28O6Forma y color:SolidPeso molecular:376.44Acetoacetic acid
CAS:<p>Acetoacetic acid(3-oxobutanoic acid) is a oxidative stress inducer, gluconeogenesis, and can be used as an indicator of in ketoacidosis.</p>Fórmula:C4H6O3Pureza:99.59% - 99.85%Forma y color:SolidPeso molecular:102.09MS1262-C3-amide-C10-amine
<p>MS1262-C3-amide-C10-amine is an E3 Ligase Ligand-Linker conjugate. It includes a GLP ligand targeting the E3 ligase SPOP and a PROTAC linker. This compound can be utilized in designing PROTACs such as example [MS479].</p>Forma y color:Odour SolidCalcineurin Autoinhibitory Peptide
CAS:<p>Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).</p>Fórmula:C124H205N39O39S2Pureza:98%Forma y color:SolidPeso molecular:2930.342-Amino-5-bromo-2’-chlorobenzophenone
CAS:<p>2-Amino-5-bromo-2’-chlorobenzophenone is an active metabolite of Phenazepam.</p>Fórmula:C13H9BrClNOForma y color:SolidPeso molecular:310.57CALP3 TFA(261969-05-5 free base)
<p>CALP3 TFA is a potent Ca2+ channel blocker that activates EF-hand motifs of Ca2+-binding proteins.</p>Fórmula:C46H69F3N10O11Pureza:98%Forma y color:SolidPeso molecular:995.1Sucunamostat hydrochloride
<p>Sucunamostat (SCO-792) hydrochloride is an orally active, reversible inhibitor of enteropeptidase, displaying inhibition constants (IC50) of 4.6 nM for rat</p>Fórmula:C22H23ClN4O8Pureza:98%Forma y color:SolidPeso molecular:506.89Myr-TAT-CBD3
<p>Myr-TAT-CBD3, a CRMP2-CaV2.2 interaction inhibitor, has been shown to significantly attenuate carrageenan-induced thermal hypersensitivity and reverse thermal</p>Fórmula:C148H269N59O33Pureza:98%Forma y color:SolidPeso molecular:3403.09MPO-IN-7
<p>MPO-IN-7 (compound MDC) is a myeloperoxidase inhibitor with IC50 values of 41 μM for α-glucosidase, 25 μM for dipeptidyl peptidase-4, and 4.5 μM for myeloperoxidase. MPO-IN-7 exhibits antioxidant and anti-inflammatory activities in vitro.</p>Fórmula:C16H14N2O6Peso molecular:330.08519N-Acetyl-Ser-Asp-Lys-Pro TFA
<p>N-Acetyl-Ser-Asp-Lys-Pro (TFA), a bone marrow tetrapeptide, is a specific ACE substrate for angiotensin conversion.</p>Fórmula:C22H34F3N5O11Pureza:98%Forma y color:SolidPeso molecular:601.53Maltodextrin, dextrose equivalent 16.5-19.5
CAS:<p>Maltodextrin (DE 16.5-19.5) is an inactive pharma excipient that enhances drug stability, solubility, and processing.</p>Fórmula:(C6H10O5)n·xH2OForma y color:SolidFZQ-21
<p>FZQ-21 (Compound 70P) is an inhibitor of the water-soluble epoxide hydrolase (sEH), with an IC50 value of 4 nM. The IC50 for inhibiting human sEH is 1.5 nM, which is comparable to that of EC5026 (1.7 nM). FZQ-21 is utilized in sepsis research.</p>Fórmula:C28H30N4O3Peso molecular:470.23179APOL1-IN-2
CAS:<p>APOL1-IN-2 (Compound 467) acts as an inhibitor of apolipoprotein L1 (APOL1). It effectively reduces HEK293 cell death induced by APOL1 G2/G1, with EC50 values of 4.74 nM and 14.3 nM, respectively. Additionally, APOL1-IN-2 decreases the mortality of trypanosomes triggered by APOL1 G2/G1/G0, with EC50 values of 2.24, 6.03, and 3.72 nM, respectively.</p>Fórmula:C28H30ClF3N4O5Forma y color:SolidPeso molecular:595.01DSPE-PEG2000-YIGSR
<p>DSPE-PEG2000-YIGSR is a PEG compound composed of DSPE and the biomimetic peptide YIGSR. YIGSR interacts with the 67 kDa laminin-binding protein (LBP), enhancing the adhesion and proliferation of various cell types, including endothelial cells, fibroblasts, and smooth muscle cells. DSPE-PEG2000-YIGSR is applicable in drug delivery.</p>Forma y color:Odour Solidα-Glucosidase-IN-44
<p>α-Glucosidase-IN-44 (compound IT4) is an α-glucosidase inhibitor with an IC50 value of 2.35 μM. This compound is orally active and has the ability to reduce fasting blood glucose levels in diabetic mice.</p>Fórmula:C23H21N3O3SPeso molecular:419.13036
