Metabolismo
Los inhibidores del metabolismo son compuestos que interfieren con las vías metabólicas, alterando la producción y utilización de energía dentro de las células. Estos inhibidores se utilizan para estudiar la regulación del metabolismo, el papel de las vías metabólicas en enfermedades como el cáncer y la diabetes, y para desarrollar nuevas estrategias terapéuticas. Los inhibidores del metabolismo pueden dirigirse a diversas enzimas y procesos involucrados en la glucólisis, la oxidación de ácidos grasos y otras funciones metabólicas. En CymitQuimica, ofrecemos una amplia gama de inhibidores del metabolismo de alta calidad para apoyar su investigación en bioquímica, trastornos metabólicos y desarrollo de fármacos.
Subcategorías de "Metabolismo"
- AhR(41 productos)
- Aminopeptidasa(67 productos)
- CETP(18 productos)
- Anhídrido carbónico(177 productos)
- Caseína quinasa(130 productos)
- DHFR(32 productos)
- Descarboxilasa(4 productos)
- Deshidrogenasa(267 productos)
- FAAH(63 productos)
- FXR(58 productos)
- Factor Xa(80 productos)
- Ácido graso sintasa(32 productos)
- Ferroptosis(215 productos)
- GR(3 productos)
- GSNOR(3 productos)
- Glucoquinasa(53 productos)
- HIF / HIF Prolilhidroxilasa(142 productos)
- HMG-CoA reductasa(32 productos)
- Hidroxilasa(30 productos)
- IDO(82 productos)
- LDL(8 productos)
- Lipasa(96 productos)
- Lípido(59 productos)
- Lipoxigenasa(124 productos)
- MAO(87 productos)
- MPO(2 productos)
- NAMPT(36 productos)
- P450(6 productos)
- PAI-1(25 productos)
- PDE(166 productos)
- PED(1 productos)
- PKM(15 productos)
- PPAR(164 productos)
- Fosfolipasa(82 productos)
- ROR(42 productos)
- Receptor de retinoides(29 productos)
- SGK(11 productos)
- Tiorredoxina(12 productos)
- Transferasa(30 productos)
- Transportador(42 productos)
- UGT(4 productos)
- Inhibidores de la xantina oxidasa (XO)(9 productos)
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Se han encontrado 8595 productos de "Metabolismo"
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IR-117-17
CAS:<p>IR-117-17 is an ionizable cationic amino lipid that targets the airways. It is degradable via esterase cleavage, making it less likely to accumulate with repeated dosing.</p>Fórmula:C59H110N2O5Forma y color:SolidPeso molecular:927.523-Hydroxysebacic acid
CAS:<p>3-Hydroxysebacic acid, an endogenous metabolite found in urine, is utilized in the study of Medium Chain Acyl-CoA Dehydrogenase Deficiency (MCADD) [1] [2].</p>Fórmula:C10H18O5Forma y color:SolidPeso molecular:218.25Remdesivir de(ethylbutyl 2-aminopropanoate)
CAS:<p>Remdesivir impurity with antiviral activity; EC50: SARS-CoV/MERS-CoV 74 nM, murine hepatitis virus 30 nM. Effective against COVID-19 in vitro.</p>Fórmula:C18H18N5O7PForma y color:SolidPeso molecular:447.34CA Ⅱ-IN-1
<p>CAⅡ-IN-1 (compound 2i) is an inhibitor of the CA Ⅱ isozyme, exhibiting an IC50 of 0.44 µM. This compound is utilized in metabolic research.</p>Fórmula:C18H19NO6SForma y color:SolidPeso molecular:377.41Mono(5-carboxy-2-ethylpentyl) phthalate
CAS:<p>MECPP is a metabolite of DEHP, a major plasticizer used in flexible PVC.</p>Fórmula:C16H20O6Forma y color:SolidPeso molecular:308.334''-C18 EGCG
<p>4''-C18 EGCG is an effective inhibitor of α-amylase and α-glucosidase, with IC50 values of 3.74 and 0.81 μM, respectively. This compound suppresses carbohydrate-hydrolyzing enzymes, reduces oxidative stress and inflammation, and exhibits anti-diabetic activity. Moreover, 4''-C18 EGCG downregulates pro-inflammatory cytokines and demonstrates cytotoxicity at 50 μM against primary human peripheral blood mononuclear cells (PBMC), as well as non-cancerous cell lines 3T3-L1 and HEK 293.</p>Fórmula:C40H54O11Forma y color:SolidPeso molecular:710.85Calcineurin Autoinhibitory Peptide
CAS:<p>Selective inhibitor of Ca2+-calmodulin-dependent protein phosphatase (calcineurin) (IC50 ~ 10 μM). Does not inhibit PP1, PP2A or CaM kinase II (IC50 > 100 mM).</p>Fórmula:C124H205N39O39S2Pureza:98%Forma y color:SolidPeso molecular:2930.34Z-Pro-prolinal
CAS:<p>Z-Pro-prolinal, an orally active PREP inhibitor, IC50: 0.4 nM in porcine.</p>Fórmula:C18H22N2O4Forma y color:SolidPeso molecular:330.387-Hydroxydichloromethotrexate
CAS:<p>7-Hydroxydichloromethotrexate is a methotrexate metabolite.</p>Fórmula:C20H20Cl2N8O6Forma y color:SolidPeso molecular:539.33Tyrosine decarboxylase
CAS:<p>TDC, a PLP-dependent enzyme, removes carboxyl groups from tyrosine, producing tyramine and CO2, found in plants, insects, and microbes.</p>Forma y color:SolidDeacetylsclerotiorin
CAS:<p>Deacetylsclerotiorin is a chloroazaphilones produced by the fungus Bartalinia robillardoides strain LF550.</p>Fórmula:C19H21ClO4Forma y color:SolidPeso molecular:348.82Speract
CAS:<p>Speract, a peptide from sea urchin eggs, regulates sperm motility and stimulates sperm mitochondrial metabolism.</p>Fórmula:C38H57N11O14Pureza:98%Forma y color:SolidPeso molecular:891.93CA IX/VEGFR-2-IN-3
<p>CAIX/VEGFR-2-IN-3 (Compound 6i) is an inhibitor of Carbonic Anhydrase IX and VEGFR-2, with IC50 values of 41 and 48 nM, respectively. It exhibits anticancer activity by inhibiting the growth of MCF-7 breast cancer cells (IC50 of 22.33 μM) and mouse fibroblast cell line 3T3, where cell viability is reduced to below 40% at a concentration of 100 μM. This compound is applicable for research in the field of cancer treatment.</p>Fórmula:C19H16ClN3O5S2Forma y color:SolidPeso molecular:465.93hCAII/IX-IN-1
<p>hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.</p>Fórmula:C23H22N4O7S2Forma y color:SolidPeso molecular:530.573PKM2 activator 6
<p>Compound Z10 (PKM2 activator 6) serves as both a PKM2 activator and a PDK1 inhibitor, exhibiting dissociation constants (K D ) of 121 μM and 19.6 μM,</p>Forma y color:Odour SolidBE2647
<p>BE2647 is a selective inhibitor of the mitochondrial pyruvate carrier (MPC), with an EC50 of 70 nM. It exhibits good metabolic stability in mouse liver microsomes. BE2647 can be utilized in research related to metabolic diseases, metabolic-associated steatotic liver disease (MASLD), or metabolic-associated steatohepatitis (MASH).</p>Fórmula:C13H7Br2N3O2Forma y color:SolidPeso molecular:397.0224-Hydroxy Atorvastatin calcium salt
CAS:<p>4-Hydroxy Atorvastatin calcium salt is metabolised by cytochrome P450 CYP3A4 and has antimicrobial and anti-microbial activity.</p>Fórmula:C66H68CaF2N4O12Forma y color:SolidPeso molecular:1187.34α-Glucosidase-IN-83
<p>α-Glucosidase-IN-83 (compound I-1) is a potent inhibitor of α-glucosidase, demonstrating an IC50 of 1.49 μg/mL. This compound effectively reduces blood glucose levels in vivo.</p>Fórmula:C25H20N4O6SForma y color:SolidPeso molecular:504.5142'-Rhamnoechinacoside
CAS:<p>2'-Rhamnoechinacoside is a naturally occurring compound sourced from Cistanche tubulosa.</p>Fórmula:C41H56O24Forma y color:SolidPeso molecular:932.9Calcium Channel antagonist 4
CAS:<p>Calcium Channel antagonist 4 is a voltage-gated calcium channel inhibitor (IC50 : 5-20 μM).</p>Fórmula:C23H26N2O4SPureza:98.09%Forma y color:SolidPeso molecular:426.53IGUANA-1
CAS:<p>IGUANA-1 is a highly efficient and selective ALDH1B1 inhibitor that inhibits the growth of colorectal cancer cells and colorectal cancer cell-derived organoids.</p>Fórmula:C27H26ClN3O4Pureza:99.08%Forma y color:SolidPeso molecular:491.97PDE4-IN-3
CAS:<p>PDE4-IN-3, a new oral drug, potently blocks PDE4 enzyme with 4.2 nM IC50.</p>Fórmula:C35H33FO8Forma y color:SolidPeso molecular:600.639GPX4-IN-16
<p>GPX4-IN-16 ((R)-9i) is a potent inhibitor of GPX4 with a KD value of 20.4 nM, exhibiting cytotoxic properties and anticancer activity.</p>Fórmula:C29H24N4O3S2Forma y color:SolidPeso molecular:540.656Cy3-PEG-DSPE (MW 3400)
<p>Cy3-PEG-DSPE (MW 3400) is a PEG phospholipid that incorporates Cy3 dye, utilized for labeling proteins/nucleic acids and in fluorescence microscopy. It can self-assemble in aqueous solutions to form micelles/lipid bilayers, and is employed in the creation of liposomes or nanoparticles for delivering nutrients such as mRNA or DNA vaccines.</p>Forma y color:SolidPeso molecular:3400 (Average)RARα antagonist 1
<p>Compound 21, an orally active and selective RARα antagonist, exhibits a potent inhibition of the retinoic acid receptor α with an IC50 of 4.6 nM [1].</p>Fórmula:C26H23NO4Forma y color:SolidPeso molecular:413.47α-Amylase/α-Glucosidase-IN-18
<p>α-Amylase/α-Glucosidase-IN-18 (Compound 9g) is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 49.17 nM and 10.71 nM, respectively. It is suitable for research related to type 2 diabetes.</p>Fórmula:C29H26N6O2SForma y color:SolidPeso molecular:522.62MEY-003
<p>MEY-003, an Autotaxin (ATX) inhibitor, exhibits EC50 values of 460 nM for hATX-β and 1.09 μM for hATX-ɣ (analysis with LPC18:1), demonstrating its potency</p>Forma y color:Odour SolidN-Desmethyl imatinib mesylate
CAS:<p>Norimatinib mesylate, N-Desmethyl imatinib metabolite, inhibits v-Abl, c-Kit, PDGFR.</p>Fórmula:C29H33N7O4SForma y color:SolidPeso molecular:575.68Ferroleuton
<p>Ferroleuton is a selective competitive inhibitor of 5-lipoxygenase with an IC50 of 0.21 μM. It demonstrates antioxidant properties, clearing 86% of DPPH at 50 μM and exhibiting activities in ABTS (EC50 = 19.42 μM) and FRAP (EC50 = 3.32 μM) assays.</p>Fórmula:C13H16FeN2O2Forma y color:SolidPeso molecular:288.12Febuxostat n-butyl isomer
CAS:<p>Febuxostat n-butyl isomer is an impurity of Febuxostat. Febuxostat is selective xanthine oxidase inhibitor with a K i of 0.6 nM [1] .</p>Fórmula:C16H16N2O3SForma y color:SolidPeso molecular:316.38Bicyclic UK18
CAS:<p>Bicyclic UK18 is a competitive inhibitor of human urokinase-type plasminogen activator (uPA) with a Ki value of 53 nM.</p>Fórmula:C77H118N26O25S3Forma y color:SolidPeso molecular:1904.11RSRGVFF
<p>RSRGVFF (FOXP3 inhibitor P60) is a mixed angiotensin-converting enzyme (ACE) inhibitor with the ability to penetrate the blood-brain barrier, exhibiting an IC50 value of 5.01 μM. It binds to both active and inactive sites of ACE and its substrate HHL complex, thereby reducing the catalytic activity of ACE. RSRGVFF can be further explored for hypertension research.</p>Fórmula:C40H61N13O9Forma y color:SolidPeso molecular:867.994C18:1 Ceramide (d18:1/18:1(9Z))
CAS:<p>C18:1 Ceramide (d18:1/18:1(9Z)) is a ceramide, and C18:1-Ceramide levels are elevated in overweight and insulin-resistant , advanced ovarian cancer.</p>Fórmula:C36H69NO3Pureza:99.96%Forma y color:SolidPeso molecular:563.94Arginase
CAS:<p>Arginase (L-Arginine amidinase) is a key hydrolytic enzyme in the urea cycle, which hydrolyzes L-arginine into urea and L-ornithine.</p>Forma y color:Solidβ-Tetralone
CAS:<p>β-Tetralone (2-Tetralone) is a vital drug synthesis precursor with complex pharmacological properties in combating neurological disorders. Cost-effective and quality-assured.</p>Fórmula:C10H10OPureza:97.26% - 99.18%Forma y color:Clear To Yellow LiquidPeso molecular:146.192-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol
CAS:<p>2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride.</p>Fórmula:C57H96O6Pureza:98%Forma y color:SolidPeso molecular:877.37Nepetalactone
CAS:<p>Nepetalactone is found in the plant Nepeta parnassica and has high mosquito repellency properties.</p>Fórmula:C10H14O2Forma y color:SolidPeso molecular:166.22Carbolactone
CAS:<p>Carbolactone is a biologically active metabolite from fungi [1] .</p>Fórmula:C24H36O3Forma y color:SolidPeso molecular:372.54Curcumin monoglucuronide
CAS:<p>Curcumin monoglucuronide, curcumin's in vivo metabolite, useful for metabolic research and cancer study.</p>Fórmula:C27H28O12Forma y color:SolidPeso molecular:544.50Acremin F
CAS:<p>Acremin F is a useful organic compound for research related to life sciences. The catalog number is T124074 and the CAS number is 863480-61-9.</p>Fórmula:C12H20O4Forma y color:SolidPeso molecular:228.288Paraherquamide E
CAS:<p>Fungal-derived paraherquamide E kills C. elegans and O. fasciatus, reduces T. colubriformis eggs in gerbils.</p>Fórmula:C28H35N3O4Forma y color:SolidPeso molecular:477.6053-keto Fusidic Acid
CAS:<p>3-keto Fusidic acid (3-keto FA) is an active metabolite of the antibiotic fusidic acid .13-keto FA is active againstM. tuberculosis(MIC99= 1.25 μM).</p>Fórmula:C31H46O6Forma y color:SolidPeso molecular:514.703Oseltamivir acid methyl ester hydrochloride
CAS:<p>Oseltamivir acid methyl ester hydrochloride, a precursor to oseltamivir, is converted by CES1.</p>Fórmula:C15H27ClN2O4Pureza:98.78%Forma y color:SoildPeso molecular:334.84Octocog alfa
CAS:<p>Octocog alfa, a second-generation, full-length recombinant antihemophilic factor VIII (AHF), is utilized for the treatment of Hemophilia A [1].</p>Forma y color:SolidHydroxydehydro Nifedipine Carboxylate
CAS:<p>Hydroxydehydro nifedipine carboxylate is a metabolite of nifedipine .1</p>Fórmula:C16H14N2O7Forma y color:SolidPeso molecular:346.295Adrenocorticotropic Hormone (ACTH) (18-39), human
CAS:<p>ACTH (18-39), or Corticotropin-like Peptide, boosts insulin, amylase, and protein secretion dose-dependently.</p>Fórmula:C112H165N27O36Pureza:98%Forma y color:SolidPeso molecular:2465.67Perflubutane
CAS:<p>Perfluorobutane is a gas that is colorless.</p>Fórmula:C4F10Pureza:98%Forma y color:Colorless Gas Colorless GasPeso molecular:238.03Sucunamostat hydrochloride
<p>Sucunamostat (SCO-792) hydrochloride is an orally active, reversible inhibitor of enteropeptidase, displaying inhibition constants (IC50) of 4.6 nM for rat</p>Fórmula:C22H23ClN4O8Pureza:98%Forma y color:SolidPeso molecular:506.89LVGRQLEEFL (mouse) (TFA)
<p>G* peptide, also known as LVGRQLEEFL (mouse) TFA, is a segment corresponding to amino acids 113 to 122 ([113,122] apoJ) of apolipoprotein J.</p>Forma y color:Odour SolidGlutamate dehydrogenase (NAD(P))
CAS:<p>GLDH, found in liver/kidney/brain/muscle/intestine, catalyzes glutamate to α-KG in urea cycle.</p>Forma y color:Solid
