PDE
Las fosfodiesterasas (PDEs) son enzimas que hidrolizan nucleótidos cíclicos, como el AMPc y el GMPc, en sus formas inactivas, desempeñando un papel clave en la regulación de las vías de señalización intracelular. Los inhibidores de PDE se utilizan en el tratamiento de diversas afecciones, como enfermedades cardiovasculares, disfunción eréctil y trastornos respiratorios, debido a su capacidad para modular los niveles de nucleótidos cíclicos. En CymitQuimica, ofrecemos una gama de inhibidores de PDE para apoyar su investigación en señalización celular, farmacología y desarrollo terapéutico.
Se han encontrado 165 productos de "PDE"
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PDE4B-IN-4
<p>PDE4B-IN-4 is an inhibitor of PDE4B (IC50: 2.82 nM) and TNF-α (IC50: 7.20 nM). It demonstrates anti-inflammatory properties by reducing neutrophilia in a mouse model of lipopolysaccharide (LPS)-induced sepsis.</p>Fórmula:C26H27N5O5Forma y color:SolidPeso molecular:489.52BAY 2666605
CAS:<p>BAY 2666605 is an orally active inhibitor of PDE3A and PDE3B with IC50s of 87 nM and 50 nM, respectively. BAY 2666605 has anticancer effects.</p>Fórmula:C17H12F4N2O2Pureza:99.81%Forma y color:SolidPeso molecular:352.28BC 11-38
CAS:<p>BC 11-38 is a potent, selective PDE biodepressant which is mainly effective against PDE11 (IC50 : 0.28 μM).</p>Fórmula:C15H16N2OS2Pureza:98.95% - 99.28%Forma y color:SolidPeso molecular:304.43Arofylline
CAS:<p>Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.</p>Fórmula:C14H13ClN4O2Pureza:98.19%Forma y color:SolidPeso molecular:304.73FCPR03
CAS:<p>FCPR03 is a selective inhibitor of phosphodiesterase 4 (PDE4) with IC50s of 31 nM, 47 nM, and 60 nM for PDE4B1, PDE4D7, and PDE4 catalytic domain, respectively.</p>Fórmula:C15H19F2NO3Pureza:99.94%Forma y color:SolidPeso molecular:299.31OPC18750 HCl
CAS:<p>OPC18750 HCl is a phosphodiesterase inhibitor with positive inotropic effects that can be used to study asthma, cancer, diabetes, and psychiatric disorders.</p>Fórmula:C20H23ClN2O4Pureza:98.92%Forma y color:SoildPeso molecular:390.86cis-Tadalafil
CAS:<p>Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.</p>Fórmula:C22H19N3O4Pureza:99.89%Forma y color:SolidPeso molecular:389.4Enpp-1-IN-14
CAS:<p>Enpp-1-IN-14: potent ENPP1 inhibitor, IC50 = 32.38 nM, exhibits anti-tumor properties.</p>Fórmula:C15H22ClN5O4SPureza:99.83%Forma y color:SoildPeso molecular:403.88PDE5-IN-9
CAS:<p>WAY-639921 treats cardiovascular and respiratory conditions by inhibiting PDE1c.</p>Fórmula:C18H14N4SPureza:99.98%Forma y color:SolidPeso molecular:318.4ONO-8430506
CAS:<p>ONO-8430506 is an orally available, potent autotaxin (ATX)/ENPP2 inhibitor (IC90: 100 nM) that inhibits ATX activity in mouse plasma.</p>Fórmula:C27H28FN3O3Pureza:98.34%Forma y color:SolidPeso molecular:461.53Acetildenafil
CAS:<p>Acetildenafil is an analog of the phosphodiesterase inhibitor sildenafil.</p>Fórmula:C25H34N6O3Forma y color:Off-White To Pale Yelow SolidPeso molecular:466.58WAY-313170
CAS:<p>WAY-313170 Inhibits hedgehog signaling and phosphodiesterase.</p>Fórmula:C19H17ClN2O2S2Pureza:99.3%Forma y color:SolidPeso molecular:404.93Oglemilast
CAS:<p>Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo.</p>Fórmula:C20H13Cl2F2N3O5SPureza:99.82%Forma y color:SolidPeso molecular:516.3(1R,2R)-MK-8189
CAS:<p>(1R,2R)-MK-8189 is an isomer of MK-8189, a potent and selective pyrimidine PDE10A inhibitor.</p>Fórmula:C19H22N6OSPureza:>99.99% - >99.99%Forma y color:SoildPeso molecular:382.48Dazonone
CAS:<p>Dazonone (Imidazo[2,1-b]quinazolin-2(3H)-one, 6-chloro-1,5-dihydro-3-methyl-) is a specific PDE III inhibitors.</p>Fórmula:C11H10ClN3OPureza:99.54% - 99.73%Forma y color:SolidPeso molecular:235.67ENPP1 Inhibitor C
CAS:<p>ML-354 (VU0099704) is an antagonist with and PAR4 for the study of cardiovascular diseases.</p>Fórmula:C15H18N6Pureza:99.28%Forma y color:SolidPeso molecular:282.34N-Ethyl tadalafil
CAS:<p>N-Ethyl tadalafil (NEthyl tadalafil) is a PDE inhibitor used in the study of cardiovascular disease.</p>Fórmula:C23H21N3O4Pureza:99.58%Forma y color:SolidPeso molecular:403.43Anti-ALDH7A1 Antibody (6G475)
<p>Anti-ALDH7A1 Antibody (6G475) is a Mouse antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (6G475) can be used in IHC-P.</p>Forma y color:Odour LiquidAnti-ALDH7A1 Antibody-FITC (5P692)
<p>Anti-ALDH7A1 Antibody-FITC (5P692) is a FITC-conjugated Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody-FITC (5P692) can be used in FCM.</p>Forma y color:Odour LiquidBAY 73-6691 racemate
CAS:<p>BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.</p>Fórmula:C15H12ClF3N4OForma y color:SolidPeso molecular:356.73
