Aminopeptidasa
Las aminopeptidasas son un grupo de enzimas que catalizan la escisión de aminoácidos desde el extremo N-terminal de péptidos y proteínas, desempeñando un papel crucial en la maduración y degradación de proteínas. Estas enzimas están involucradas en varios procesos fisiológicos, incluyendo el procesamiento de antígenos, la regulación de hormonas peptídicas y la homeostasis celular. Los inhibidores de aminopeptidasas son de interés en el tratamiento de enfermedades como el cáncer, la inflamación y las enfermedades infecciosas. En CymitQuimica, ofrecemos una variedad de inhibidores de aminopeptidasas para apoyar su investigación en proteómica, desarrollo de medicamentos y tratamiento de enfermedades.
Se han encontrado 67 productos de "Aminopeptidasa"
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PPI-2458
CAS:<p>PPI-2458, a fumagillin derivative, irreversibly blocks MetAP2, hindering abnormal cell growth and angiogenesis with improved toxicity.</p>Fórmula:C22H36N2O6Forma y color:SolidPeso molecular:424.53QGC583
CAS:<p>QGC583 is an effective and selective AminopeptidaseA (APA) inhibitor, demonstrating an IC50 of 4 nM. It inhibits APA activity in the brain, kidneys, and heart of rats.</p>Fórmula:C13H20NO5PForma y color:SolidPeso molecular:301.284-MDM
CAS:<p>4-MDM (4-Methoxydiphenylmethane) is an orally active anti-inflammatory compound that selectively enhances the aminopeptidase activity of leukotriene A4 hydrolase (LTA4H). By promoting the degradation of proline-glycine-proline by LTA4H, 4-MDM reduces neutrophil recruitment in the lungs, alleviating inflammation without affecting the epoxide hydrolase activity of LTA4H. This compound is useful for research in pulmonary diseases.</p>Fórmula:C14H14OForma y color:SolidPeso molecular:198.26ERAP1 modulator-2
CAS:<p>ERAP1 modulator-2 (compound 10) is a potent ERAP1 inhibitor with an IC50 value of less than 100 nM.</p>Fórmula:C22H25F3N2O4SForma y color:SolidPeso molecular:470.505Beloranib
CAS:<p>Beloranib is a fumagillin anticancer drug. Beloranib belongs to an angiogenesis inhibitor.</p>Fórmula:C29H41NO6Pureza:98%Forma y color:SolidPeso molecular:499.64TNP-470
CAS:<p>TNP-470 is a methionine aminopeptidase-2 inhibitor. TNP-470 is also an angiogenesis inhibitor.</p>Fórmula:C19H28ClNO6Pureza:98%Forma y color:SolidPeso molecular:401.88Actinonin
CAS:<p>Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM. It also induces apoptosis and inhibits aminopeptidase M, aminopeptidase N, and leucine aminopeptidase, as well as MMP-1, MMP-3, MMP-8, MMP-9, and meprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin exhibits antiproliferative and antitumor activities [1][2][3][4][5].</p>Fórmula:C19H35N3O5Forma y color:SolidPeso molecular:385.5
