Receptor de retinoides
Los receptores de retinoides son receptores nucleares que median los efectos de los retinoides (derivados de la vitamina A) sobre la expresión génica. Estos receptores juegan un papel vital en la diferenciación celular, la proliferación y la apoptosis. Los inhibidores de los receptores de retinoides se utilizan para estudiar su implicación en diversas enfermedades, incluyendo el cáncer, los trastornos cutáneos y las condiciones metabólicas. Al modular la actividad de los receptores de retinoides, estos inhibidores pueden proporcionar información sobre los mecanismos de señalización de los retinoides y su potencial terapéutico. En CymitQuimica, ofrecemos inhibidores de los receptores de retinoides para apoyar su investigación en dermatología, oncología y regulación metabólica.
Se han encontrado 21 productos de "Receptor de retinoides"
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BMS 195614
CAS:BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.Fórmula:C29H24N2O3Pureza:97.14%Forma y color:SolidPeso molecular:448.51CD3254
CAS:CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.Fórmula:C24H28O3Pureza:98.71% - 98.71%Forma y color:SolidPeso molecular:364.48trifarotene
CAS:Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.
Fórmula:C29H33NO4Pureza:99.51%Forma y color:SolidPeso molecular:459.58palovarotene
CAS:Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).
Fórmula:C27H30N2O2Pureza:97.88% - 98.05%Forma y color:SolidPeso molecular:414.54AR7
CAS:AR7 is a retinoic acid receptor α (RARα) antagonist.Fórmula:C15H12ClNOPureza:98.12% - 99.86%Forma y color:SolidPeso molecular:257.71Ref: TM-T3955
1mg37,00€5mg69,00€10mg96,00€25mg202,00€50mg329,00€100mg550,00€200mg758,00€500mg1.159,00€1mL*10mM (DMSO)74,00€Fenretinide
CAS:Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.Fórmula:C26H33NO2Pureza:98% - 99.68%Forma y color:Yellow PowderPeso molecular:391.55Bexarotene
CAS:Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).Fórmula:C24H28O2Pureza:99% - 99.65%Forma y color:White SolidPeso molecular:348.48CD2665
CAS:CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.Fórmula:C31H34O5Pureza:99.71%Forma y color:SolidPeso molecular:486.6BMS270394
CAS:BMS270394 is a RARγ agonist used in the study of breast cancer and skin diseases.Fórmula:C23H26FNO4Forma y color:SolidPeso molecular:399.46AGN 196996
CAS:AGN 196996: strong RARα inhibitor (Ki: 2 nM), weak for RARβ/γ (Ki: 1087/8523 nM).Fórmula:C24H20BrNO5Pureza:99.94%Forma y color:SolidPeso molecular:482.32Ref: TM-T10261
1mg59,00€5mg131,00€10mg190,00€25mg329,00€50mg477,00€100mg702,00€1mL*10mM (DMSO)138,00€BMS 753
CAS:BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).Fórmula:C21H21NO4Pureza:98.55%Forma y color:SolidPeso molecular:351.4AC-261066
CAS:AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0.Fórmula:C17H20FNO4SPureza:99.64%Forma y color:SolidPeso molecular:353.41MM 11253
CAS:MM 11253 is a RARγ antagonist with IC50 of 44nM.Fórmula:C28H30O2S2Pureza:99.41%Forma y color:SolidPeso molecular:462.67Ch55
CAS:Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.Fórmula:C24H28O3Pureza:99.55%Forma y color:SolidPeso molecular:364.48Ref: TM-T14946
1mg39,00€5mg82,00€10mg117,00€25mg240,00€50mg374,00€100mg580,00€200mg798,00€1mL*10mM (DMSO)89,00€Fluorobexarotene
CAS:Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 nM and EC50 of 43 nM for RXRα.Fórmula:C24H27FO2Pureza:99.08%Forma y color:SolidPeso molecular:366.47Ref: TM-T11303
1mg170,00€5mg416,00€10mg615,00€25mg964,00€50mg1.305,00€100mg1.755,00€500mg3.501,00€1mL*10mM (DMSO)335,00€KCL-286
CAS:KCL-286 is an available and potent retinoic acid receptor beta agonist for the amelioration of spinal cord injury (SCI).Fórmula:C19H14N2O4Pureza:99.93%Forma y color:SolidPeso molecular:334.33BMS641
CAS:BMS641 (BMS-209641) is a RARβ agonist with affinity for RARβ that synergistically activates RARβ and RARgamma to induce cell maturation.Fórmula:C27H23ClO2Pureza:98.11%Forma y color:SolidPeso molecular:414.92Ref: TM-T26854
1mg94,00€5mg226,00€10mg378,00€25mg730,00€50mg1.035,00€100mg1.406,00€200mg1.890,00€1mL*10mM (DMSO)249,00€ER 50891
CAS:ER-50891 is a potent RARα antagonist, countering retinoic acid inhibition and aiding BMP2-induced osteoblast differentiation.Fórmula:C29H24N2O2Pureza:99.43%Forma y color:SolidPeso molecular:432.51LE135
CAS:LE135: RARα/RARβ antagonist (Ki: 1.4 μM/220 nM), favors RARβ, selective vs RARγ/RXRs; also activates TRPV1/TRPA1 (EC50s: 2.5/20 μM).Fórmula:C29H30N2O2Pureza:97.94%Forma y color:SolidPeso molecular:438.56Ref: TM-T22920
1mg47,00€2mg62,00€5mg92,00€10mg135,00€25mg217,00€50mg324,00€100mg472,00€1mL*10mM (DMSO)97,00€ZSH-2208
CAS:ZSH-2208 is a retinoic acid A analogue that inhibits tumour cell proliferation and survival through RARγ-TNFAIP3 and retinoid receptors.Fórmula:C20H18O3SPureza:99.81%Forma y color:SolidPeso molecular:338.42
