Receptor de retinoides
Los receptores de retinoides son receptores nucleares que median los efectos de los retinoides (derivados de la vitamina A) sobre la expresión génica. Estos receptores juegan un papel vital en la diferenciación celular, la proliferación y la apoptosis. Los inhibidores de los receptores de retinoides se utilizan para estudiar su implicación en diversas enfermedades, incluyendo el cáncer, los trastornos cutáneos y las condiciones metabólicas. Al modular la actividad de los receptores de retinoides, estos inhibidores pueden proporcionar información sobre los mecanismos de señalización de los retinoides y su potencial terapéutico. En CymitQuimica, ofrecemos inhibidores de los receptores de retinoides para apoyar su investigación en dermatología, oncología y regulación metabólica.
Se han encontrado 29 productos de "Receptor de retinoides"
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LG-100064
CAS:<p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>Fórmula:C23H26O3Pureza:98.65%Forma y color:SolidPeso molecular:350.45BMS 195614
CAS:<p>BMS 195614 (BMS614) is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit.</p>Fórmula:C29H24N2O3Pureza:97.7%Forma y color:SolidPeso molecular:448.51CD3254
CAS:<p>CD3254 is a selective and potent retinoid X receptor-like (RXR) agonist that inhibits neuronal cell death with OGD/reoxygenation.</p>Fórmula:C24H28O3Pureza:98.71% - 98.71%Forma y color:SolidPeso molecular:364.48CD437
CAS:<p>CD437 (AHPN) is a specifc Retinoic Acid Receptor γ (RARγ) agonist.</p>Fórmula:C27H26O3Pureza:98.92% - 99.63%Forma y color:SolidPeso molecular:398.49Tazarotene
CAS:<p>Tazarotene (Zorac), a synthetic topical retinoid, treats psoriasis by normalizing keratinocytes and reducing growth.</p>Fórmula:C21H21NO2SPureza:97.01% - 99.14%Forma y color:White SolidPeso molecular:351.46Fenretinide
CAS:<p>Fenretinide (4-HPR) is an orally-active synthetic retinoid derivative with potential antineoplastic and chemopreventive activities.</p>Fórmula:C26H33NO2Pureza:98% - 99.68%Forma y color:Yellow PowderPeso molecular:391.55AGN 193109
CAS:<p>AGN 193109, a retinoid analog, is a potent and specific antagonist of RARs (Kds: 2 nM, 2 nM, and 3 nM for RARα, RARβ, and RARγ).</p>Fórmula:C28H24O2Pureza:99.87% - 99.89%Forma y color:SolidPeso molecular:392.49UVI 3003
CAS:<p>UVI 3003 blocks retinoid X receptor (RXRα) in Xenopus/human Cos7 cells; IC50: 0.22/0.24 μM.</p>Fórmula:C28H36O4Pureza:99.82%Forma y color:SolidPeso molecular:436.58AR7
CAS:<p>AR7 is a retinoic acid receptor α (RARα) antagonist.</p>Fórmula:C15H12ClNOPureza:98.12% - 99.86%Forma y color:SolidPeso molecular:257.71palovarotene
CAS:<p>Palovarotene (Ro 3300074) is an agonist of nuclear retinoic acid receptor γ (RAR-γ).</p>Fórmula:C27H30N2O2Pureza:97.88% - 98.05%Forma y color:SolidPeso molecular:414.54Tarenflurbil
CAS:<p>Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.</p>Fórmula:C15H13FO2Pureza:98% - 99.9%Forma y color:SolidPeso molecular:244.26trifarotene
CAS:<p>Trifarotene (CD5789) is a RARγ agonist, 65x more selective than RARα and 16x than RARβ, with EC50 of 7.7 nM.</p>Fórmula:C29H33NO4Pureza:99.51%Forma y color:SolidPeso molecular:459.58Bexarotene
CAS:<p>Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).</p>Fórmula:C24H28O2Pureza:99% - 99.65%Forma y color:White SolidPeso molecular:348.48BMS270394
CAS:<p>BMS270394 is a RARγ agonist used in the study of breast cancer and skin diseases.</p>Fórmula:C23H26FNO4Forma y color:SolidPeso molecular:399.46CD 1530
CAS:<p>CD 1530 is an ARγ agonist (Kd:150 nM) with potential anticancer activity for the study of oral carcinogenesis.</p>Fórmula:C27H26O3Pureza:98.13%Forma y color:SolidPeso molecular:398.49CD2665
CAS:<p>CD2665 is an orally active antagonist of retinoic acid receptor (RAR). For RARγ and RARβ, the Kis are 110 nM and 306 nM.</p>Fórmula:C31H34O5Pureza:99.71%Forma y color:SolidPeso molecular:486.6Ch55
CAS:<p>Ch55, a potent HL60 cell differentiator (EC50=200nM), binds well to RAR-α/β, useful for cancer research.</p>Fórmula:C24H28O3Pureza:99.55%Forma y color:SolidPeso molecular:364.48AGN 196996
CAS:<p>AGN 196996: strong RARα inhibitor (Ki: 2 nM), weak for RARβ/γ (Ki: 1087/8523 nM).</p>Fórmula:C24H20BrNO5Pureza:98.74%Forma y color:SolidPeso molecular:482.32BMS 753
CAS:<p>BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM).</p>Fórmula:C21H21NO4Pureza:98.55%Forma y color:SolidPeso molecular:351.4Fluorobexarotene
CAS:<p>Fluorobexarotene, a potent RXR agonist, has 75% higher affinity than Bexarotene with Ki of 12 nM and EC50 of 43 nM for RXRα.</p>Fórmula:C24H27FO2Pureza:99.08%Forma y color:SolidPeso molecular:366.47
