Factor Xa
El factor Xa es una enzima crucial en la cascada de coagulación que convierte la protrombina en trombina, lo que lleva a la formación de coágulos sanguíneos. La inhibición del factor Xa es una estrategia terapéutica ampliamente utilizada para prevenir y tratar los trastornos tromboembólicos, como la trombosis venosa profunda, la embolia pulmonar y el accidente cerebrovascular. En CymitQuimica, ofrecemos inhibidores del factor Xa para apoyar su investigación en hematología, salud cardiovascular y terapia anticoagulante.
Se han encontrado 85 productos de "Factor Xa"
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Eribaxaban
CAS:Eribaxaban (PD348292) is an orally available factor Xa inhibitor for the prevention and treatment of venous thromboembolism.Fórmula:C24H22ClFN4O4Pureza:98.99% - 99.13%Forma y color:SolidPeso molecular:484.91YM-75466
CAS:YM-75466 is a factor Xa inhibitor reducing TAT in plasma dose-dependently without prolonging coagulation.Fórmula:C28H35N5O8S2Forma y color:SolidPeso molecular:633.74Ciraparantag TFA
CAS:Ciraparantag TFA reverses anticoagulants by inhibiting thrombin and factor Xa.Fórmula:C26H50F6N12O6Pureza:98%Forma y color:SolidPeso molecular:740.74BMS 740808
CAS:BMS-740808 is a highly effective and selective factor X inhibitor.Fórmula:C31H27F3N6O3Forma y color:SolidPeso molecular:588.58Milvexian TFA
CAS:Milvexian (BMS-986177/JNJ-70033093) is a factor XIa inhibitor with Ki=44 nM for kallikrein, Ki=35 nM for chymotrypsin, 32% bioavailability.Fórmula:C30H26Cl2F5N9O4Forma y color:SolidPeso molecular:742.49Ciraparantag
CAS:Ciraparantag inhibits thrombin, factor Xa, and reverses various anticoagulants.Fórmula:C22H48N12O2Pureza:98%Forma y color:SolidPeso molecular:512.7Darexaban glucuronide
CAS:Darexaban glucuronide is the major component in plasma after oral administration of darexaban to humans. Darexaban (YM150) is a direct inhibitor of factor Xa.Fórmula:C33H38N4O10Forma y color:SolidPeso molecular:650.68Tanogitran
CAS:Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.Fórmula:C25H31N7O3Pureza:98%Forma y color:SolidPeso molecular:477.56DPC-423
CAS:DPC-423 is a factor Xa inhibitor potentially for the treatment of thrombosis.Fórmula:C25H21ClF4N4O3SPureza:98%Forma y color:SolidPeso molecular:568.97Razaxaban hydrochloride
CAS:Razaxaban hydrochloride is a highly potent, selective and orally active inhibitor of factor Xa(Ki of 0.19 nM),has strongly antithrombotic activity.Fórmula:C24H21ClF4N8O2Pureza:98%Forma y color:SolidPeso molecular:564.92Otamixaban
CAS:Otamixaban (FXV673) is a selective and highly effective Xa inhibitor that inhibits the generation of thrombin and can be used to study acute coronary syndrome.Fórmula:C25H26N4O4Pureza:98.08%Forma y color:SolidPeso molecular:446.5Pegnivacogin
CAS:Pegnivacogin is a coagulation factor IXa RNA aptamer inhibitor.Fórmula:C20H40N3O11PPureza:98%Forma y color:SolidPeso molecular:529.52Edoxaban
CAS:Edoxaban: potent, selective FXa inhibitor; Ki 0.561 nM. Used as an oral anticoagulant for stroke prevention, also inhibits thrombin and FIXa.Fórmula:C24H30ClN7O4SPureza:97.67% - 99.71%Forma y color:SolidPeso molecular:548.06Fidexaban
CAS:<p>Fidexaban (CI1031) is a novel, potent, selective and orally active factor Xa inhibitor that has demonstrated antithrombotic activity in a variety of assays</p>Fórmula:C25H24F2N6O5Pureza:98.64% - 99.43%Forma y color:SolidPeso molecular:526.49LY 517717
CAS:LY 517717 is an orally active inhibitor of coagulation factor Xa with antithrombotic activity for the study of venous thromboembolism (VTE).Fórmula:C27H33N5O2Pureza:99.77% - 99.88%Forma y color:SolidPeso molecular:459.58Zifaxaban
CAS:Zifaxaban (TY-602) is an oral selective factor Xa inhibitor with an IC50 of 11.1 nM, highly specific over other serine proteases, used in thrombosis studies.Fórmula:C20H16ClN3O4SPureza:97.46% - 99.82%Forma y color:SolidPeso molecular:429.88BI-11634
CAS:BI-11634 is a factor Xa inhibitor.Fórmula:C22H23ClN4NaO4Pureza:98%Forma y color:SolidPeso molecular:465.89BMS-654457
CAS:BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa; Kis: 0.2 and 0.42 nM for human and rabbit FXIa).Fórmula:C36H37N5O4Pureza:98%Forma y color:SolidPeso molecular:603.71Frunexian
CAS:Frunexian (EP-7041) is a selective and potent inhibitor of coagulation factor XI/activated factor XI, specifically targeting XIa.Fórmula:C19H26N4O4Pureza:98%Forma y color:SolidPeso molecular:374.43BMS-262084
CAS:BMS-262084 is a potent selective β-lactam trypsin inhibitor with therapeutic potential in the treatment of asthma.Fórmula:C18H31N7O5Forma y color:SolidPeso molecular:425.48FXIa-IN-1
CAS:FXIa-IN-1 is a potent β-lactam covalent heparin-derived factor XIa (fXIa) inhibitor.Fórmula:C20H19F3N4O5Pureza:98%Forma y color:SolidPeso molecular:452.38AS1468240
CAS:AS1468240 is a factor Xa inhibitor. It has significant oral anticoagulant activity.Fórmula:C25H25Cl2N5O3Forma y color:SolidPeso molecular:514.4FXa-IN-1
CAS:FXa-IN-1, an FXa blocker: IC50=3 nM, Ki=0.7 nM, orally available, long half-life, for thrombosis research.Fórmula:C24H18F5N5OForma y color:SolidPeso molecular:487.42FXIa-IN-7
CAS:FXIa-IN-7 is an orally available, selective and potent inhibitor of factor XIa for the study of thrombophilia.Fórmula:C28H28N2O4Pureza:98.55%Forma y color:SolidPeso molecular:456.53BMS-962212
CAS:BMS-962212: reversible, selective FXIa blocker, well-tolerated, quick PD effect, rapid clearance, alters clotting time/activity.Fórmula:C32H28ClFN8O5Pureza:98%Forma y color:SolidPeso molecular:659.07Dechloro Rivaroxaban
CAS:<p>Dechloro Rivaroxaban is a Factor Xa inhibitor that inhibits free FXa and plasminogen and fibrin-associated FXa activity in humans.</p>Fórmula:C19H19N3O5SPureza:98.63%Forma y color:SolidPeso molecular:401.44FXIa-IN-8
FXIa-IN-8: potent FXIa blocker (IC50: 14.2 nM), anti-thrombotic, low bleeding/toxicity risk.Forma y color:SolidFXIa-IN-10
FXIa-IN-10 is a potent, orally bioavailable inhibitor of Activator XI (FXIa) (Ki: 0.17 nM).Fórmula:C23H18Cl2F3N9O2Forma y color:SolidPeso molecular:580.35FXIa-IN-6
CAS:FXIa-IN-6: Potent, selective FXIa inhibitor (Ki=0.3 nM); strong PK with high oral bioavailability, low clearance preclinically.Fórmula:C31H29ClF2N4O4Forma y color:SolidPeso molecular:595.04FXIa-6f
CAS:<p>FXIa-6f is a high affinity, orally bioavailable macrocyclic FXIa inhibitor with antithrombotic activity in preclinical species</p>Fórmula:C31H29ClF2N4O4Forma y color:SolidPeso molecular:595.04DX-9065A HCl hydrate
CAS:<p>DX-9065a: Competitive fXa/prothrombinase inhibitor; blocks proinflammatory events; Ki ~10-20 nM.</p>Fórmula:C26H39ClN4O8Pureza:98%Forma y color:SolidPeso molecular:571.06RWJ-445167
CAS:RWJ-445167 is a thrombin and factor Xa dual inhibitor(Ki of 4.0 nM and 230 nM, respectively), with potent antithrombotic activity.Fórmula:C18H24N6O5SPureza:98%Forma y color:SolidPeso molecular:436.49FXIa-IN-9
CAS:FXIa-IN-9, a potent FXIa inhibitor (K i : human 0.17 nM, rabbit 0.5 nM), forms hydrogen bonds and has anticoagulant properties.Fórmula:C23H18Cl2F3N9O2Forma y color:SolidPeso molecular:580.35BAY 3389934
CAS:BAY 3389934 is a dual inhibitor of factor IIa (factor IIa) and factor Xa (factor Xa), providing anticoagulant and organ-protective effects. It alleviates coagulopathy and organ dysfunction in baboon models of Staphylococcus aureus sepsis.Fórmula:C26H30ClN5O7S2Forma y color:SolidPeso molecular:624.1295-Chlorothiophene-2-carboxylic acid
CAS:5-Chlorothiophene-2-carboxylic acid [catalog number: T66447, CAS number: 24065-33-6] is a valuable organic compound for life sciences research.Fórmula:C5H3ClO2SForma y color:SolidPeso molecular:162.59
