IDO
La indoleamina 2,3-dioxigenasa (IDO) es una enzima involucrada en el catabolismo del triptófano, que lleva a la producción de quinurenina y otros metabolitos. La IDO juega un papel en la tolerancia inmune y a menudo está sobreexpresada en el cáncer y en condiciones inflamatorias crónicas. Los inhibidores de IDO se están explorando como posibles agentes inmunoterapéuticos en el cáncer y en enfermedades autoinmunes. En CymitQuimica, ofrecemos inhibidores de IDO para apoyar su investigación en inmunología, oncología y regulación metabólica.
Se han encontrado 84 productos de "IDO"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PROTAC IDO1 Degrader-1
CAS:First potent PROTAC IDO1 degrader; links IDO1 to CRBN E3 ligase for UPS-induced degradation (DC50=2.84 μM), boosts H ER2 CAR-T cell efficacy.Fórmula:C40H53BrFN9O13Forma y color:SolidPeso molecular:966.816(Rac)-IDO1-IN-5
CAS:(Rac)-IDO1-IN-5 is a racemic, potent IDO1 inhibitor; selective for apo-IDO1, it crosses the blood-brain barrier.Fórmula:C23H25FN2O3Forma y color:SolidPeso molecular:396.45Anti-IDO1 Antibody (9Y885)
Anti-IDO1 Antibody (9Y885) is an antibody targeting IDO1. Anti-IDO1 Antibody (9Y885) can be used in ELISA, IHC.Forma y color:Odour LiquidIDO1 Protein, Human, Recombinant
IDO Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 45.2 kDa and the accession number is A0A348GSI3.Forma y color:Lyophilized PowderPeso molecular:45.2 kDa (predicted); 46 kDa (reducing conditions)IDO1 Protein, Human, Recombinant (His)
IDO Protein, Human, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:46 kDa (predicted); 44 kDa (reducing conditions)IDO1/TDO-IN-4
CAS:IDO1/TDO-IN-4 is a novel dual inhibitor of IDO1/TDO with antidepressant activity, forming hydrogen bonds with IDO1 and π-π stacking interactions with TDO.Fórmula:C14H10N4Pureza:98.88%Forma y color:SolidPeso molecular:234.26(S)-IDO1-IN-5
CAS:(S)-IDO1-IN-5 is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL(IC50 value less than 1.5 μΜ).Fórmula:C23H25FN2O3Forma y color:SolidPeso molecular:396.45IDO1 Protein, Mouse, Recombinant (His)
IDO Protein, Mouse, Recombinant (His) is expressed in E.Pureza:≥ 90 % as determined by SDS-PAGE. - ≥ 90 % as determined by SDS-PAGE.Forma y color:Lyophilized PowderPeso molecular:46.47 kDa (predicted)Epacadostat
CAS:Epacadostat (INCB 024360) is an oral, potent and selective IDO1 inhibitor with IC50 value of 71.8 nM.Cost-effective and quality-assured.Fórmula:C11H13BrFN7O4SPureza:98% - >99.99%Forma y color:SolidPeso molecular:438.23Ref: TM-T3548
1g757,00€2g1.035,00€5mg47,00€10mg70,00€25mg87,00€50mg111,00€100mg187,00€200mg311,00€500mg525,00€1mL*10mM (DMSO)50,00€IDO5L
CAS:IDO5L (INCB024360 analogue) is an effective IDO1 inhibitor(IC50=10 nM).Fórmula:C9H7ClFN5O2Pureza:99.49% - 99.75%Forma y color:SolidPeso molecular:271.64Ref: TM-T2647
10mg50,00€25mg86,00€50mg124,00€100mg187,00€200mg321,00€500mg505,00€1mL*10mM (DMSO)35,00€BMS-986242
CAS:BMS-986242 is an orally active, potent and selective inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1), and it can be used for the research of cancer.Fórmula:C24H24ClFN2OPureza:98.9%Forma y color:SolidPeso molecular:410.91PF-06840003
CAS:PF-06840003 (EOS200271) is a specific and oral active IDO-1 inhibitor.Fórmula:C12H9FN2O2Pureza:99.10%Forma y color:SolidPeso molecular:232.21Ref: TM-T4307
2mg35,00€5mg52,00€10mg93,00€25mg107,00€50mg127,00€100mg188,00€200mg283,00€1mL*10mM (DMSO)58,00€IDO-IN-7
CAS:IDO-IN-7 (NLG-919 analogue) is a potent IDO (indoleamine-(2, 3)-dioxygenase) pathway inhibitor.Fórmula:C18H22N2OPureza:99.32% - 99.9%Forma y color:SolidPeso molecular:282.383-TYP
CAS:<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Fórmula:C7H6N4Pureza:99.16% - >99.99%Forma y color:SolidPeso molecular:146.15LM10
CAS:TDO inhibitor; IC50: human 0.62 μM, mouse 2 μM; selective over IDO, MAOs; hinders TDO+ tumor growth in mice; orally active.Fórmula:C11H8FN5Pureza:98.78% - 99.94%Forma y color:SolidPeso molecular:229.21Linrodostat
CAS:Linrodostat (BMS-986205) is a selective indoleamine 2, 3-dioxygenase 1 (IDO1) inhibitor.Fórmula:C24H24ClFN2OPureza:99.54% - 99.71%Forma y color:SolidPeso molecular:410.91PCC0208009
CAS:PCC0208009 (IDO-IN-2) is an IDO inhibitor.Fórmula:C29H35N7OPureza:99.89%Forma y color:SolidPeso molecular:497.63Ref: TM-T4142
1mg47,00€2mg59,00€5mg87,00€10mg150,00€25mg271,00€50mg464,00€100mg640,00€1mL*10mM (DMSO)97,00€(S)-Indoximod
CAS:(S)-Indoximod (L-Abrine) is an indoleamine-2,3-dioxygenase (IDO) inhibitor for cancer research.Fórmula:C12H14N2O2Pureza:95.39% - 99.69%Forma y color:SolidPeso molecular:218.25Navoximod
CAS:Navoximod (GDC-0919) (NLG- 919, GDC-0919) is a potent indoleamine-(2,3)-dioxygenase (IDO) pathway inhibitor (Ki/EC50: 7 nM/75 nM).Fórmula:C18H21FN2O2Pureza:99.37%Forma y color:SolidPeso molecular:316.37Ref: TM-TQ0071
1mg159,00€5mg329,00€10mg495,00€25mg633,00€50mg787,00€100mg1.103,00€1mL*10mM (DMSO)335,00€IDO1-IN-1
CAS:IDO1-IN-1 (2 HzBTZ) is an indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor.Fórmula:C7H7N3SPureza:99.36%Forma y color:Slightly Yellow To Beige-Green Crystalline PowderPeso molecular:165.22
