Anhídrido carbónico
La anhidrasa carbónica es una enzima que cataliza la conversión reversible de dióxido de carbono y agua en bicarbonato y protones. Esta enzima juega un papel crucial en el mantenimiento del equilibrio ácido-base, la respiración y el transporte de dióxido de carbono en la sangre. Los inhibidores de la anhidrasa carbónica se utilizan en el tratamiento del glaucoma, la epilepsia y el mal de altura, así como en la investigación sobre la homeostasis ácido-base y el intercambio de gases. En CymitQuimica, ofrecemos una gama de inhibidores de la anhidrasa carbónica y reactivos de alta calidad para apoyar su investigación en enzimología, fisiología respiratoria y desarrollo terapéutico.
Se han encontrado 196 productos de "Anhídrido carbónico"
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Actarit
CAS:Actarit (4-acetylaminophenylacetic acid) is an anti-inflammatory drug.Fórmula:C10H11NO3Pureza:99.64% - 99.74%Forma y color:White Or Off-White Crystal Or Crystalline SolidPeso molecular:193.2Tioxolone
CAS:Tioxolone is a metalloenzyme carbonic anhydrase I inhibitor.Fórmula:C7H4O3SPureza:97.79%Forma y color:Light Yellow To Beige PowderPeso molecular:168.17Topiramate
CAS:Topiramate (RWJ 17021) is a unique antiseizure medication that is used in the treatment of partial and generalized seizures.Fórmula:C12H21NO8SPureza:99.79% - 99.92%Forma y color:White To Off-White Crystalline PowderPeso molecular:339.36Zonisamide
CAS:Zonisamide (AD 810), a sulfonamide anticonvulsant, is approved for use as an adjunctive treatment in adults with partial-onset seizures.Fórmula:C8H8N2O3SPureza:99.05% - 99.9%Forma y color:Off-White PowderPeso molecular:212.23Benzthiazide
CAS:Benzthiazide treats edema and hypertension by promoting diuresis and inhibiting kidney Na+/Cl- reuptake, but may reduce potassium and raise uric acid.
Fórmula:C15H14ClN3O4S3Pureza:99.34% - 99.79%Forma y color:Crystals From Acetone SolidPeso molecular:431.94Acipimox
CAS:Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.Fórmula:C6H6N2O3Pureza:98.98%Forma y color:Low Yellow Liquid Or CrystallinePeso molecular:154.12Methocarbamol
CAS:Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established.Fórmula:C11H15NO5Pureza:99.96%Forma y color:Crystals From Benzene SolidPeso molecular:241.24Brinzolamide
CAS:Brinzolamide (AL-4862) is a Carbonic Anhydrase Inhibitor. The mechanism of action of brinzolamide is as a Carbonic Anhydrase Inhibitor.Fórmula:C12H21N3O5S3Pureza:99.84% - >99.99%Forma y color:Crystalline SolidPeso molecular:383.51pNNP
CAS:pNNP is a substrate for PP2C assays and inhibits β-carbonic anhydrase, α-carbonate dehydrogenase, and H. pylori.Fórmula:C6H6NO6PPureza:99.82%Forma y color:SolidPeso molecular:219.09Methazolamide
CAS:Methazolamide (CL 8490) is a carbonic anhydrase inhibitor that is used as a diuretic and in the treatment of glaucoma.Fórmula:C5H8N4O3S2Pureza:99.31% - 99.77%Forma y color:Crystals From Water SolidPeso molecular:236.27hCAII/XII-IN-1
hCAII/XII-IN-1 (compound 4l) is a potent inhibitor of hCAXII and hCAII, with Ki values of 8.4 nM and 9.4 nM, respectively. It plays a significant role in cancer research.Fórmula:C22H20N4O6S2Forma y color:SolidPeso molecular:500.547hCAII-IN-6
"hCAII-IN-6 (S-13) inhibits hCA II (4.4 nM) and isoforms I, IV, IX (9.2, 480.2, 14.7 nM). For glaucoma research."Fórmula:C20H25N3O4SForma y color:SolidPeso molecular:403.5Acesulfame
CAS:Acesulfame inhibits CA9/12 and can be used to study inflammation-related diseases.Fórmula:C4H5NO4SForma y color:SolidPeso molecular:163.15CAII/CAXII-IN-1
CAII/CAXII-IN-1 (compound 8d) is an inhibitor of CAII and CAXII, with IC50 values of 0.38 µM for CAII and 0.61 µM for CAXII.Forma y color:Odour SolidhCAIX-IN-17
hCA IX-IN-1 inhibits hCA I/II/IX/XII with Ki of 331.4/28.4/9.4/17.8 nM, has anticancer properties.Fórmula:C19H18N2O3SForma y color:SolidPeso molecular:354.42Phenylsulfamide
CAS:Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and anFórmula:C6H8N2O2SForma y color:SolidPeso molecular:172.2hCAIX/XII-IN-9
hCAIX/XII-IN-9 (compound 8) is a potent inhibitor of carbonic anhydrase (CA), with Ki values of 1658 nM for hCA I, 184.8 nM for hCA II, 8.9 nM for hCA IX, and 64.8 nM for hCA XII.Fórmula:C26H25N5O5S2Peso molecular:551.12971Girentuximab
CAS:Girentuximab (G250) is an anti-carbonic anhydrase IX (CAIX) monoclonal antibody with anti-cancer activity for the study of uroepithelial carcinoma PET (ZiPUP).Forma y color:LiquidPeso molecular:145.55 kDahCAIX/XII-IN-11
hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.Fórmula:C13H10FN3O4Peso molecular:291.06553α-Pyrone
CAS:Alpha-Pyrone exhibits inhibitory activity against tyrosinase, carbonic anhydrase 1, and carbonic anhydrase 9Fórmula:C5H4O2Forma y color:SolidPeso molecular:96.08CAXII-IN-2
CAXII-IN-2 (compound 3j) is a highly effective inhibitor of CAXII. It demonstrates inhibitory activity against CA IX and CAXII, with Ki values of 27.4 nM and 4.0 nM, respectively.Fórmula:C16H13FNO4PForma y color:SolidPeso molecular:333.05662CAIX/CAXII-IN-3
CAIX/CAXII-IN-3 (compound 11) serves as an inhibitor for CAIX/CAXII, exhibiting an IC50 value of less than 65 nM. Additionally, this compound effectively inhibits the proliferation of human melanoma cells.Forma y color:Odour Solid(E)-Dehydrodiconiferyl alcohol
CAS:(E)-Dehydrodiconiferyl alcohol inhibits hCA IX/XII enzymes and blocks NF-κB nuclear translocation in healing tissues.Fórmula:C20H22O6Forma y color:SolidPeso molecular:358.39hCAII-IN-7
hCAII-IN-7 (R-13) inhibits human CA I, II, IV, IX with K i of 60.7, 320.7, 2298, 35.2 nM respectively.Fórmula:C20H25N3O4SForma y color:SolidPeso molecular:403.5GZ22-4
GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.Fórmula:C88H126F3N6NaO24S4Peso molecular:1858.75561Carbonic anhydrase inhibitor 32
Carbonic anhydrase inhibitor32 (compound 5B) is an orally active, selective inhibitor of hCA (carbonic anhydrase) II/VII, with Ki values of 6.3 nM for hCA II, 10.1 nM for hCA VII, and 681 nM for hCA I. It shows potential for neuroprotection and anticonvulsant effects by reducing mTOR activation and increasing hippocampal KCC2 levels.Fórmula:C17H16N6O3SForma y color:SolidPeso molecular:384.41hCAII/IX-IN-1
hCAII/IX-IN-1 (compound 4o) is a potent inhibitor of hCAII and hCAIX, with Ki values of 7.4 nM and 7.0 nM, respectively. It plays a significant role in cancer research.Fórmula:C23H22N4O7S2Forma y color:SolidPeso molecular:530.5735,6-Dihydro-2H-pyran-2-one
CAS:5,6-Dihydro-2H-pyran-2-one is a carbonic anhydrase 1/9 inhibitor that inhibits KB cell viability.Fórmula:C5H6O2Forma y color:SolidPeso molecular:98.1Carbonic anhydrase inhibitor 30
Carbonic anhydrase inhibitor30 (compound 17) is an inhibitor of carbonic anhydrase with Ki values of 2.13 μM for hCA I and 0.161 μM for hCA II[1].Fórmula:C23H22FN3O5SForma y color:SolidPeso molecular:471.12642Chlorothiazide
CAS:Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Forma y color:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.722-Methoxy-4-propylphenol
CAS:2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.
Fórmula:C10H14O2Forma y color:SolidPeso molecular:166.22Pyrocatechol
CAS:Pyrocatechol, often known as catechol or benzene-1,2-diol, is a benzenediol, Pyrocatechol was produced at a large scale industrially, mainly as precursors to pesticides, flavors, and fragrances. Its sulfonic acid is often present in the urine of many mammals.Fórmula:C6H6O2Pureza:99.96%Forma y color:SolidPeso molecular:110.11VM4-037
CAS:VM4-037 is a PET imaging agent used for carbonic anhydrase IX.Fórmula:C26H29FN6O7S2Forma y color:SolidPeso molecular:620.67hCA/Wnt/β-catenin-IN-1
hCA/Wnt/β-catenin-IN-1 (Compd 15) serves as an inhibitor with selective affinity for hCA isoforms II, IX, and XII, exhibiting K i values of 33.6, 24.1, and 6.8Forma y color:Odour SolidCAIX/CAXII-IN-4
CAIX/CAXII-IN-4 (Compound 7h) is an inhibitor of carbonic anhydrase (CA) that binds to CAIX, CA XII, and CAII with Ki values of 1.324 μM, 0.435 μM, and 3.035 μM, respectively. This compound exhibits broad-spectrum anti-tumor activity and inhibits the proliferation of central nervous system tumor cells U251, with a GI50 of 0.361 μM.Fórmula:C23H21N5O3SForma y color:SolidPeso molecular:447.51TSPO/Carbonic Anhydrase Modulator 1
TSPO/Carbonic Anhydrase Modulator 1 (Compound 3) acts as a dual modulator of mitochondrial translocator protein and carbonic anhydrase, with a TSPOKi of 1.340 μM and a CAVII KA of 10.7 μM. It enhances neurosteroid production, increases BDNF gene expression, and demonstrates neuroprotective activity.Fórmula:C35H51N3O3Forma y color:SolidPeso molecular:561.798hCA/VEGFR-2-IN-3
hCA/VEGFR-2-IN-3 (compound 8j) is an indolinonylbenzenesulfonamide with potential as a dual inhibitor of cancer-associated hCA IX/XII and VEGFR-2.Fórmula:C24H28N6O6SPureza:98%Forma y color:SolidPeso molecular:528.58hCA/VEGFR-2-IN-2
Compound 8g (hCA/VEGFR-2-IN-2) is an indolinonylbenzenesulfonamide identified as a potential dual inhibitor targeting cancer-associated isozymes hCA IX/XII andFórmula:C23H26N6O5SPureza:98%Forma y color:SolidPeso molecular:498.55Dorzolamide
CAS:Dorzolamide is an anti-glaucoma agent and is a carbonic anhydrase inhibitor.
Fórmula:C10H16N2O4S3Pureza:98%Forma y color:White Or Almost White Crystalline PowderPeso molecular:324.44hCAIX/XII-IN-14
hCAIX/XII-IN-14 (Compound 1i) is an inhibitor of hCAIX and hCAXII, with Ki values of 9.4 nM for hCAII, 5.6 nM for hCAIX, and 6.3 nM for hCAXII.Fórmula:C16H14F3N3O4SForma y color:SolidPeso molecular:401.36DOTA-XYIMSR-01
CAS:DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.Fórmula:C61H88N16O22S2Forma y color:SolidPeso molecular:1461.57DPP IV/hCA II-IN-1
CAS:DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).Fórmula:C17H20N2O5SForma y color:SolidPeso molecular:364.42hCAIX-IN-19
hCAIX-IN-19 is a sulfonamide inhibitor with an inhibition constant (KI) of 6.2 nM for hCAIX, exhibiting significant selectivity towards hCAIX over hCAI (hCA I/Forma y color:Odour SolidhCAI/II-IN-10
hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.Fórmula:C24H17Cl2N3O3S2Forma y color:SolidPeso molecular:530.446hCAII-IN-8
CAS:Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.Fórmula:C15H16N2O5SPureza:99.73%Forma y color:SoildPeso molecular:336.36Ref: TM-T67774
5mg42,00€10mg64,00€25mg116,00€50mg167,00€100mg241,00€200mg339,00€1mL*10mM (DMSO)52,00€hCA/VEGFR-2-IN-4
hCA/VEGFR-2-IN-4 (compound 15b), an indolinylbenzenesulfonamide, serves as a potential dual inhibitor targeting cancer-related human carbonic anhydrases hCA IX/Fórmula:C22H23FN6O5SPureza:98%Forma y color:SolidPeso molecular:502.52Carbonic anhydrase inhibitor 31
Carbonic anhydrase inhibitor31 is an mtCA2 inhibitor (Ki: 5.2 nM) that can be used in antituberculosis research.Fórmula:C24H20N6O5SForma y color:SolidPeso molecular:504.12159Carbonic anhydrase inhibitor 29
Carbonic anhydrase inhibitor29 (Compound 5d) is an inhibitor targeting carbonic anhydrase IX and XII, with an inhibition constant (Ki) of 26.6 nM for carbonic anhydrase IX and a Ki of 10.9 nM for carbonic anhydrase XII. Carbonic anhydrase inhibitor29 can be used in cancer research.Forma y color:Odour SolidCAIX Inhibitor S4
CAS:CAIX Inhibitor S4 (S4) is an effective inhibitor of carbonic anhydrase IX/XII with a Ki of 7 nM and 2 nM, respectively.
Fórmula:C15H17N3O4SPureza:99.07%Forma y color:SolidPeso molecular:335.38Carbonic anhydrase inhibitor 18
Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.Fórmula:C26H28N4O6S2Peso molecular:556.14503
