Anhídrido carbónico
La anhidrasa carbónica es una enzima que cataliza la conversión reversible de dióxido de carbono y agua en bicarbonato y protones. Esta enzima juega un papel crucial en el mantenimiento del equilibrio ácido-base, la respiración y el transporte de dióxido de carbono en la sangre. Los inhibidores de la anhidrasa carbónica se utilizan en el tratamiento del glaucoma, la epilepsia y el mal de altura, así como en la investigación sobre la homeostasis ácido-base y el intercambio de gases. En CymitQuimica, ofrecemos una gama de inhibidores de la anhidrasa carbónica y reactivos de alta calidad para apoyar su investigación en enzimología, fisiología respiratoria y desarrollo terapéutico.
Se han encontrado 178 productos de "Anhídrido carbónico"
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hCAII-IN-8
CAS:<p>Compound CDy9 is a highly selective inhibitor of carbonic anhydrase (CA) with an IC50 value of 0.18 μM for hCA II.</p>Fórmula:C15H16N2O5SPureza:99.73%Forma y color:SoildPeso molecular:336.36hCAI/II-IN-10
<p>hCAI/II-IN-10 (Compound 5d) is an inhibitor of human carbonic anhydrase I and II (hCA I and hCA II), with IC50 values of 4.32 nM and 3.89 nM, respectively.</p>Fórmula:C24H17Cl2N3O3S2Forma y color:SolidPeso molecular:530.446DPP IV/hCA II-IN-1
CAS:<p>DPP IV/hCA II-IN-1: strong DPP IV & CA inhibitor, IC50=0.049μM (DPP IV), Ki=0.0361-3.034μM (CA II-IV).</p>Fórmula:C17H20N2O5SForma y color:SolidPeso molecular:364.42Bendroflumethiazide
CAS:<p>Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)</p>Fórmula:C15H14F3N3O4S2Pureza:98% - >99.99%Forma y color:Crystals From Dioxane SolidPeso molecular:421.41Carbonic anhydrase
CAS:<p>Carbonic anhydrase, a zinc enzyme in all life forms, converts CO2 to bicarbonate; studied for cancer, glaucoma, obesity, epilepsy.</p>Forma y color:SolidCarbonic anhydrase inhibitor 26
<p>Compound 6T, designated as Carbonic anhydrase inhibitor26, acts as an inhibitor of Carbonic Anhydrase II (Carbonic AnhydraseII), exhibiting an IC50 value of 9.10 ± 0.26 μM.</p>Fórmula:C17H14N6O4Forma y color:SolidPeso molecular:366.33AV22-149
<p>AV22-149 (compound 22) is an inhibitor of Carbonic Anhydrase .</p>Fórmula:C23H28F3N3O6S2Forma y color:SolidPeso molecular:563.61DOTA-XYIMSR-01
CAS:<p>DOTA-XYIMSR-01 is a molecular probe targeting CAIX, capable of being labeled with 177Lu for the treatment and localization of malignant gliomas. The uptake of [177Lu]Lu-XYIMSR-01 in U87MG tumors is 6.19% injected dose per gram (% ID/g), with a tumor-to-muscle uptake ratio of 20.14. In an orthotopic glioma model, co-administration with temozolomide significantly enhances survival rates and inhibits tumor growth in mice. DOTA-XYIMSR-01 shows potential for research in the field of cancer treatment.</p>Fórmula:C61H88N16O22S2Forma y color:SolidPeso molecular:1461.57Carbonic anhydrase inhibitor 18
<p>Carbonic anhydrase inhibitor18 (Compound 9) is an inhibitor of human carbonic anhydrase (hCA) isozymes, with Ki values of 604.8 nM for hCA I, 333.6 nM for hCA II, 1.9 nM for hCA IX, and 6.7 nM for hCA XII. Carbonic anhydrase inhibitor18 is applicable in cancer research.</p>Fórmula:C26H28N4O6S2Peso molecular:556.14503GZ22-4
<p>GZ22-4 is a near-infrared (NIR) fluorescent probe with a high affinity for carbonic anhydrase IX (CAIX), exhibiting a dissociation constant (Kd) of 0.2 nM. It is applicable in studies for visualizing CAIX-positive tumors.</p>Fórmula:C88H126F3N6NaO24S4Peso molecular:1858.75561hCAIX/XII-IN-11
<p>hCAIX/XII-IN-11 (Compound 6c) is an inhibitor of hCA IX and hCA XII, exhibiting Ki values of 0.7 μM for both isoforms. This compound is applicable in cancer research.</p>Fórmula:C13H10FN3O4Peso molecular:291.06553SH7s
<p>SH7s is an effective carbonic anhydrase inhibitor, exhibiting Ki values of 15.9 nM for hCA IX and 55.2 nM for hCA XII. Additionally, SH7s acts as a hypoxia-mediated chemosensitizer in colorectal cancer cells.</p>Fórmula:C24H19ClF3N5O4SForma y color:SolidPeso molecular:565.95hCA XII-IN-6
<p>Compound 4d, known as hCA XII-IN-6, is a potent inhibitor of human carbonic anhydrase XII (hCA XII) with a Ki value of 84.2 nM and exhibits anti-proliferative</p>Fórmula:C11H9N5O3S2Pureza:98%Forma y color:SolidPeso molecular:323.35Chlorothiazide
CAS:<p>Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.</p>Fórmula:C7H6ClN3O4S2Pureza:98.46% - 98.91%Forma y color:Crystals Physical Description Crystals; White Powder (Ntp 1992)Peso molecular:295.72Acetazolamide-d3
CAS:<p>Acetazolamide D3 is a deuterium-labeled Acetazolamide. Acetazolamide is a potent carbonic anhydrase inhibitor.</p>Fórmula:C4H6N4O3S2Pureza:98%Forma y color:SolidPeso molecular:225.26Carbonic Anhydrase 12 Protein, Cynomolgus, Recombinant (His)
<p>Carbonic anhydrases (CAs) are a family of enzymes involved in the pH regulation of metabolically active cells/tissues.</p>Forma y color:Lyophilized PowderPeso molecular:32.04 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.M 12325
CAS:<p>M 12325 is used in the production of furosemide; rhinitis and occupational asthma were observed in workers from a lasamide production line.</p>Fórmula:C7H5Cl2NO4SForma y color:White To Almost White Solid PowderPeso molecular:270.09EMAC10101d
CAS:<p>compound EMAC10101d, bearing a 2,4-dichorophenyl substituent in position 4 of the dihydrothiazole ring, was the most potent and selective toward hCA II with an</p>Fórmula:C17H15Cl2N3O2S2Pureza:99.96%Forma y color:SolidPeso molecular:428.36Benzenesulfonamide
CAS:<p>Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.</p>Fórmula:C6H7NO2SPureza:99.42% - 99.99%Forma y color:White Crystalline PowderPeso molecular:157.19Dichlorphenamide
CAS:<p>Dichlorphenamide (Diclofenamide) is a carbonic anhydrase inhibitor that is used in the treatment of glaucoma.</p>Fórmula:C6H6Cl2N2O4S2Pureza:96.87% - 97.25%Forma y color:Needles From Dimethylsulfoxide + Water SolidPeso molecular:305.16Benzolamide
CAS:<p>Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.</p>Fórmula:C8H8N4O4S3Pureza:99.31%Forma y color:SolidPeso molecular:320.37Dichlorphenamide disodium
CAS:<p>Dichlorphenamide disodium: an oral carbonic anhydrase inhibitor that lowers eye pressure, promising for glaucoma study.</p>Fórmula:C6H6Cl2N2Na2O4S2Forma y color:SolidPeso molecular:351.12Dimethylfraxetin
CAS:<p>Dimethylfraxetin (6,7,8-Trimethoxycoumarin) is a Carbonic anhydrase inhibitor(Ki：0.0097 μM)</p>Fórmula:C12H12O5Pureza:99.96% - ≥95%Forma y color:SolidPeso molecular:236.224-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide
CAS:<p>4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide (4-Amino-6-(trifluoromethyl)benzene-1,3-d) is a carbonic anhydrase inhibitor, used as a potential anti-</p>Fórmula:C7H8F3N3O4S2Pureza:98.58%Forma y color:SolidPeso molecular:319.28Dorzolamide hydrochloride
CAS:<p>Dorzolamide hydrochloride (MK507 hydrochloride) is the hydrochloride salt form of dorzolamide, an inhibitor of carbonic anhydrase, a zinc-containing enzyme that</p>Fórmula:C10H17ClN2O4S3Pureza:99.48% - 99.67%Forma y color:White Off-White Crystalline PowderPeso molecular:360.9Methyclothiazide
CAS:<p>Methyclothiazide (Aquatensen) is a substituted benzothiadiazide, used to treat high blood pressure and fluid retention caused by various conditions including</p>Fórmula:C9H11Cl2N3O4S2Pureza:99.13%Forma y color:SolidPeso molecular:360.242,3-dihydro-1H-indene-5-sulfonamide
CAS:<p>2,3-dihydro-1H-indene-5-sulfonamide is Carbonic anhydrase 12 (human) inhibitor.</p>Fórmula:C9H11NO2SPureza:99.89%Forma y color:SolidPeso molecular:197.25Orthanilamide
CAS:<p>Orthanilamide (Orthanilamide) is a molecule containing the sulfonamide functional group attached to an aniline.</p>Fórmula:C6H8N2O2SPureza:99.72% - 99.96%Forma y color:White To Pale Cream Crystalline Powder Or CrystalsPeso molecular:172.2Indisulam
CAS:<p>Indisulam (E 7070) is a dual-action anticancer drug, blocking G1/S cell cycle transition by degrading cyclin E and activating p53/p21.</p>Fórmula:C14H12ClN3O4S2Pureza:98.68% - 99.77%Forma y color:SolidPeso molecular:385.85U-104
CAS:<p>U-104 (NSC-213841) is an effective carbonic anhydrase (CA) inhibitor for CA IX( Ki=45.1 nM) and CA XII(Ki=4.5 nM).</p>Fórmula:C13H12FN3O3SPureza:98.76% - 99.88%Forma y color:SolidPeso molecular:309.32Ethoxzolamide
CAS:<p>Ethoxzolamide (L-643786) is a carbonic anhydrase inhibitor.</p>Fórmula:C9H10N2O3S2Pureza:98.27% - 99.62%Forma y color:Crystals From Ethyl Acetate + Skellysolve B SolidPeso molecular:258.32Polmacoxib
CAS:<p>Polmacoxib, a first-class NSAID, dual inhibitor of CA and COX-2, may hinder colorectal cancer growth in mice.</p>Fórmula:C18H16FNO4SPureza:97.88%Forma y color:SolidPeso molecular:361.39Fluorometholone Acetate
CAS:<p>Fluorometholone Acetate (Oxylone acetate) is a synthetic corticosteroid, used in the treatment of steroid responsive inflammatory conditions of the eye.</p>Fórmula:C24H31FO5Pureza:99.76%Forma y color:SolidPeso molecular:418.50Brinzolamide hydrochloride
<p>Brinzolamide (AL-4862) HCl selectively inhibits carbonic anhydrase II, reducing IOP for glaucoma research. IC50: 3.2 nM.</p>Forma y color:Solid4-(benzyloxy)benzene-1-sulfonamide
CAS:<p>4-(benzyloxy)benzene-1-sulfonamide is inhibitor of human recombinant CA-7.</p>Fórmula:C13H13NO3SPureza:97.54%Forma y color:SolidPeso molecular:263.31Zolamide
CAS:<p>Zolamide (CL 5343) may be used to prevent altitude sickness and reduce the symptoms.</p>Fórmula:C2H4N4O2S2Pureza:99.75%Forma y color:SolidPeso molecular:180.21hCA I-IN-2
CAS:<p>hCA I-IN-2 (6d) inhibits hCA I (Ki: 18.8 nM) more selectively over II, IX, XII (Ki: 375.1, 1721, 283.9 nM).</p>Fórmula:C26H20BrN5O3SForma y color:SolidPeso molecular:562.44Disulfamide
CAS:<p>Disulfamide: Oral carbonic anhydrase inhibitor, IC50 0.07 μM, diuretic by blocking Na+/HCO3- reabsorption.</p>Fórmula:C7H9ClN2O4S2Pureza:98.1%Forma y color:SolidPeso molecular:284.74HCAIX-IN-2
CAS:<p>HCAIX-IN-2 (compound 9d) is a selective inhibitor of carbonic anhydrase and acts on hCA IX (Ki: 24.6 nM) and hCA XII (Ki: 45.3 nM).</p>Fórmula:C19H16N8O4SForma y color:SolidPeso molecular:452.45hCAIX-IN-11
CAS:<p>hCAIX-IN-11 inhibits carbonic anhydrases IX & XII with Ki of 32.7 nM & 623.5 nM, respectively.</p>Fórmula:C21H15ClN4O3Forma y color:SolidPeso molecular:406.82hCAI/II-IN-1
CAS:<p>hCAI/II-IN-1 (Compound 3h) is a human carbonic anhydrase I and II (hCA I/II) inhibitor that acts on hCA I (IC50: 0.047 μM) and hCA II (IC50: 0.024 μM).</p>Fórmula:C18H29N5O3S3Forma y color:SolidPeso molecular:459.65hCAIX/XII-IN-2
CAS:<p>Compound 6a: Selective hCAIX/XII inhibitor; Ki: 30 nM (hCAIX), 3.6 nM (hCAXII); >10,000 nM (hCAI/II).</p>Fórmula:C19H14N2O4Forma y color:SolidPeso molecular:334.33CDK2-IN-12
CAS:<p>CDK2-IN-12 (10b), potent CDK2 inhibitor, IC50: 11.6 μM; inhibits hCA I/II/IX/XII, KI: 3534/638.4/44.3/48.8 nM; anti-cancer properties.</p>Fórmula:C20H17N9O2SForma y color:SolidPeso molecular:447.47Clofenamide
CAS:<p>Clofenamide is a low-ceiling sulfonamide diuretic.</p>Fórmula:C6H7ClN2O4S2Forma y color:SolidPeso molecular:270.71hCAII-IN-2
CAS:<p>hCAII-IN-2 inhibits human carbonic anhydrases I, II, IX, XII with Ki values of 261.4, 3.8, 19.6, 45.2 nM respectively.</p>Fórmula:C25H18ClN5O4SForma y color:SolidPeso molecular:519.96hCAIX/XII-IN-3
CAS:<p>Compound 6q inhibits hCAIX/CAXII; K i : hCAI >10000 nM, hCAII >10000 nM, hCAIX 66.2 nM, hCAXII 4.4 nM.</p>Fórmula:C20H13F3N2O4Forma y color:SolidPeso molecular:402.32CDK2-IN-11
CAS:<p>CDK2-IN-11 inhibits CDK2 (IC50: 6.4 μM) and targets hCA II, IX, XII (Ki: 23.4-56.3 nM); suited for cancer research.</p>Fórmula:C18H14ClN7O2SForma y color:SolidPeso molecular:427.87hCA I-IN-1
CAS:<p>hCA I-IN-1 inhibits hCA I (Ki: 38.3 nM), II (Ki: 716.4 nM), IX (Ki: 940.1 nM), XII (Ki: 192.8 nM).</p>Fórmula:C27H23N5O4SForma y color:SolidPeso molecular:513.57hCAXII-IN-3
CAS:<p>hCAXII-IN-3 (Compound 6o) is a selective inhibitor of human carbonic anhydrase XII (hCAXII) (Ki: 10.0 nM).</p>Fórmula:C26H20BrN5O3SForma y color:SolidPeso molecular:562.44Carbonic anhydrase inhibitor 14
CAS:<p>CA inhibitor 14 blocks hCA I/II/IX/XII (K i of 1203/99.7/9.4/27.7 nM) and CDK2 (IC50: 20.3 μM), showing antitumor effects.</p>Fórmula:C18H17N7O2SForma y color:SolidPeso molecular:395.44
