Anhídrido carbónico
La anhidrasa carbónica es una enzima que cataliza la conversión reversible de dióxido de carbono y agua en bicarbonato y protones. Esta enzima juega un papel crucial en el mantenimiento del equilibrio ácido-base, la respiración y el transporte de dióxido de carbono en la sangre. Los inhibidores de la anhidrasa carbónica se utilizan en el tratamiento del glaucoma, la epilepsia y el mal de altura, así como en la investigación sobre la homeostasis ácido-base y el intercambio de gases. En CymitQuimica, ofrecemos una gama de inhibidores de la anhidrasa carbónica y reactivos de alta calidad para apoyar su investigación en enzimología, fisiología respiratoria y desarrollo terapéutico.
Se han encontrado 198 productos para "Anhídrido carbónico".
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Valerate sodium
CAS:Valerate sodium is a potential Carbonic anhydrase 1/2 inhibitor for biochemical experiments.Fórmula:C5H9NaO2Pureza:99.84% - 99.91%Forma y color:White SolidPeso molecular:124.11Carbonic anhydrase inhibitor 4
CA inhibitor 4, photoprobe; targets hCA I-XIV; Ki: 640-1166 nM.Fórmula:C21H18N2O4SForma y color:SolidPeso molecular:394.44CA IX-IN-1
CA IX-IN-1 (compound 12g) is a potent and highly selective hCA IX inhibitor (IC50: 7 nM) that exhibits antitumour effects.Fórmula:C16H22N4O8SForma y color:SolidPeso molecular:430.43CA IX-IN-3
CAS:CAIX-IN-3 (Compound 27) is a selective and potent inhibitor of carbonic anhydrase IX (CAIX), with an IC50 of 0.48 nM.Fórmula:C21H19N5O4S2Forma y color:SolidPeso molecular:469.537Thioaspirine
CAS:Thioaspirine is a carbonic anhydrase (CA) inhibitor with Ki values of 64.3 μM for hCA II and 10.9 μM for hCA IX. It effectively alleviates inflammatory pain in mice induced by complete Freund's adjuvant (CFA). Thioaspirine is applicable for research on inflammatory pain.Fórmula:C9H8O3SPeso molecular:196.22CAII-IN-1
CAII-IN-1 (3n) is a selective bovine CA-II inhibitor with 10.3 μM IC50, used in carbonic anhydrase disorder studies.Fórmula:C19H21FN4SForma y color:SolidPeso molecular:356.46Sulclamide
CAS:Sulclamide, a sulfamoylbenzoic acid derivative, exhibits diuretic activity and functions as an inhibitor of carbonic anhydrase [1].Fórmula:C7H7ClN2O3SForma y color:SolidPeso molecular:234.66hCAVII/IX-IN-1
CAS:hCAVII/IX-IN-1 (compound 4) functions as an inhibitor of hCAVII/IX, exhibiting Ki values of 56.5 nM and 38.2 nM, respectively. It is applicable in the field of cancer research.Fórmula:C7H7N3O2S2Forma y color:SolidPeso molecular:229.279CAII-IN-3
CAII-IN-3, a thiosemicarbazone, potently inhibits CA-II with an IC50 of 13.4 μM.Fórmula:C18H18F2N4SForma y color:SolidPeso molecular:360.42β-Glucuronidase/hCAII-IN-2
β-Glucuronidase/hCAII-IN-2 is a potent inhibitor of β-glucuronidase and hCA II, and their IC50 values were 670.7 μM and 21.77 μM, respectively.Fórmula:C31H23NO8Forma y color:SolidPeso molecular:537.52Carbonic anhydrase inhibitor 3
Carbonic anhydrase inhibitor 3 (compound 11g) is an inhibitor of carbonic anhydrase II that reduces the intraocular pressure in glaucomatous rabbits [1].Fórmula:C15H17N3O3SForma y color:SolidPeso molecular:319.38CAII/VII-IN-1
CAS:CAII/VII-IN-1 is an orally active inhibitor of hCA II (KI= 12.3 nM) and hCA VII (KI= 22.6 nM), showing no significant activity towards hCA I. In vivo, it demonstrates excellent neuroprotective properties in a Pilocarpine-induced epilepsy model. It upregulates KCC2 and inhibits mTOR, contributing to its neuroprotective effects. CAII/VII-IN-1 exhibits no significant neurotoxicity or changes in liver and kidney function, making it a useful compound for epilepsy research.Fórmula:C27H23ClN8O5S2Peso molecular:639.1Carbonic anhydrase inhibitor 2
CAS:Compound 7c inhibits carbonic anhydrase II, lowering intraocular pressure in glaucomatous rabbits.Fórmula:C12H16N4O6SForma y color:SolidPeso molecular:344.34EGFR/VEGFR2-IN-2
EGFR/VEGFR2-IN-2 (compound 4b) serves as a dual inhibitor of VEGFR-2 and EGFR.Fórmula:C24H15FO3Forma y color:SolidPeso molecular:370.37hCAIX-IN-20
CAS:hCAIX-IN-20 (compound APBS-5m) is a potent inhibitor of carbonic anhydrase IX (hCA IX), with a Ki of 2.7 nM, playing a significant role in cancer research.Fórmula:C19H13Cl2N5O4S2Forma y color:SolidPeso molecular:510.37Carbonic anhydrase inhibitor 17
CAS:Carbonic anhydrase inhibitor 17 (compound 7c) is a pyrazine-based sulfonamide that acts as a carbonic anhydrase II inhibitor, with an IC50 value of 0.63 nM.Fórmula:C18H15ClN4O3S2Forma y color:SolidPeso molecular:434.92Carbonic anhydrase inhibitor 19
CAS:Carbonic anhydrase inhibitor19 (compound 26a) targets glaucoma-associated isozymes hCA II and hCA XII, with inhibition constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound is effective in reducing intraocular pressure.Fórmula:C23H25N3O6S2Forma y color:SolidPeso molecular:503.592-Methoxy-4-propylphenol
CAS:2-Methoxy-4-propylphenol is an inhibitor of human carbonic anhydrase isoenzymes 1/2/9/12 and has antifungal activity.Fórmula:C10H14O2Forma y color:SolidPeso molecular:166.22
