FAAH
La hidrolasa de amidas de ácidos grasos (FAAH) es una enzima que descompone las amidas de ácidos grasos, incluidos los endocannabinoides como la anandamida. Estos compuestos están involucrados en la regulación del dolor, el estado de ánimo, el apetito y la memoria. La inhibición de la FAAH puede aumentar los niveles de estas moléculas de señalización, ofreciendo beneficios terapéuticos potenciales para el dolor, la ansiedad y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una selección de inhibidores de FAAH para apoyar su investigación en neurociencia, manejo del dolor y señalización endocannabinoide.
Se han encontrado 64 productos de "FAAH"
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CAY10435
CAS:<p>CAY10435, a β-ketooxazapyridine and selective FAAH inhibitor, exhibits antimicrobial properties. It binds non-competitively to the FAAH of Dictyostelium discoideum, demonstrating a Kd value of 0.57 nM [1] [2].</p>Fórmula:C18H26N2O2Forma y color:SolidPeso molecular:302.41FAAH/cPLA2α-IN-1
CAS:<p>FAAH/cPLA2α-IN-1 is a compound that simultaneously inhibits both FAAH and cPLA2α, demonstrating potent activity with half-maximal inhibitory concentrations (</p>Fórmula:C19H26N4O5Pureza:98%Forma y color:SolidPeso molecular:390.43OMDM-5
CAS:<p>OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).</p>Fórmula:C26H44N2O3Pureza:99.73%Forma y color:SolidPeso molecular:432.64JP104
CAS:<p>JP104 is an aryl carbamate that irreversibly inhibits fatty acid amide hydrolase (FAAH) with a pIC50 value of approximately 8 [1].</p>Fórmula:C25H30N2O3Pureza:98%Forma y color:SolidPeso molecular:406.52PDP-EA
CAS:<p>PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.</p>Fórmula:C25H43NO3Pureza:99.59%Forma y color:SolidPeso molecular:405.61FAAH inhibitor 2
CAS:<p>FAAH Inhibitor 2 (Compound 17b) is an irreversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrating an IC50 value of 0.153 μM [1].</p>Fórmula:C24H40N2O2Forma y color:SolidPeso molecular:388.59Sob-AM2
CAS:<p>Sob-AM2 is an effective substrate targeting the fatty acid amide hydrolase (FAAH) expressed in the brain, with a Km of 1.3 μM. It delivers higher concentrations of Sobetirome to the central nervous system at minimal peripheral systemic doses, thereby activating the central thyroid hormone receptor β (TRβ).</p>Fórmula:C21H27NO3Forma y color:SolidPeso molecular:341.44MK-3168 (12C)
CAS:<p>MK-3168 (12C) functions as a FAAH inhibitor, exhibiting IC50 values of 1.0 nM, 5.5 nM, and 1.7 nM for human, rhesus, and rat respectively. It demonstrates effective brain uptake and FAAH-specific signaling. Additionally, 11 C MK-3168 is applicable as a FAAH PET tracer.</p>Fórmula:C21H21ClN4OSForma y color:SolidPeso molecular:412.94FAAH/MAGL-IN-1
<p>FAAH/MAGL-IN-1 (SIH 3) inhibits FAAH & MAGL with IC50 of 31 & 29 nM, useful in neuropathic pain research.</p>Fórmula:C15H9Cl2N3O3Forma y color:SolidPeso molecular:350.16FAAH/MAGL-IN-2
CAS:<p>FAAH/MAGL-IN-2: potent, reversible, oral FAAH & MAGL inhibitor, IC50: 11/36 nM, may research neuropathic pain, no locomotion issue.</p>Fórmula:C15H13Cl2N3O3SForma y color:SolidPeso molecular:386.25FAAH/MAGL-IN-3
<p>FAAH/MAGL-IN-3 irreversibly inhibits FAAH (IC50: 179 nM) & MAGL (IC50: 759 nM) with low PAMPA permeability.</p>Fórmula:C21H25N3O6SForma y color:SolidPeso molecular:447.5AZ513
CAS:<p>AZ513 is a reversible FAAH inhibitor, exhibiting an IC50 of 551 nM for human FAAH and 27 nM for rat FAAH. It inhibits the hydrolysis of arachidonoyl ethanolamide in HEK293 cells transfected with human FAAH, with an IC50 of 360 nM.</p>Fórmula:C14H9Cl2N3OForma y color:SolidPeso molecular:306.147Dual FAAH/sEH-IN-1
CAS:<p>Dual FAAH/sEH-IN-1 inhibits both sEH (IC50: 9.6 nM) and FAAH (IC50: 7 nM), offering potent anti-inflammatory effects.</p>Fórmula:C25H22ClN3O3S2Pureza:99.89%Forma y color:SolidPeso molecular:512.04TC-F 2
CAS:<p>TC-F 2 is a FAAH inhibitor.</p>Fórmula:C26H25N5O2Pureza:98%Forma y color:SolidPeso molecular:439.51
