FAAH
La hidrolasa de amidas de ácidos grasos (FAAH) es una enzima que descompone las amidas de ácidos grasos, incluidos los endocannabinoides como la anandamida. Estos compuestos están involucrados en la regulación del dolor, el estado de ánimo, el apetito y la memoria. La inhibición de la FAAH puede aumentar los niveles de estas moléculas de señalización, ofreciendo beneficios terapéuticos potenciales para el dolor, la ansiedad y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una selección de inhibidores de FAAH para apoyar su investigación en neurociencia, manejo del dolor y señalización endocannabinoide.
Se han encontrado 63 productos para "FAAH".
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N-Benzylpalmitamide
CAS:N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for theFórmula:C23H39NOPureza:97.08% - 99.77%Forma y color:SolidPeso molecular:345.5619Biochanin A
CAS:Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Fórmula:C16H12O5Pureza:97.59% - 99.68%Forma y color:Yellow SolidPeso molecular:284.2635JNJ-42165279
CAS:JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.Fórmula:C18H17ClF2N4O3Pureza:99.88% - 99.95%Forma y color:SolidPeso molecular:410.8024-Nonylphenylboronic acid
CAS:4-Nonylphenylboronic acid is a inhibitor of FAAH.Fórmula:C15H25BO2Pureza:97.63%Forma y color:SolidPeso molecular:248.169URB-597
CAS:URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.Fórmula:C20H22N2O3Pureza:97.20% - 98.24%Forma y color:White SolidPeso molecular:338.4N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Fórmula:C25H37NOPureza:98.7% - 99.92%Forma y color:SolidPeso molecular:367.5674AA38-3
CAS:AA38-3 (1-Piperidinecarboxylic acid, 4-nitrophenyl ester) inhibites three SHs (ABHD6, ABHD11, and FAAH)Fórmula:C12H14N2O4Pureza:99.56%Forma y color:SolidPeso molecular:250.2506FAAH inhibitor 2
CAS:FAAH Inhibitor 2 (Compound 17b) is an irreversible inhibitor of fatty acid amide hydrolase (FAAH), demonstrating an IC50 value of 0.153 μM [1].Fórmula:C24H40N2O2Forma y color:SolidPeso molecular:388.59AKU-005
CAS:AKU-005 is a dual inhibitor of FAAH and MAGL, exhibiting IC50 values of 63 nM and 389 nM against rat and human FAAH, respectively. This compound has potential for researching trigeminal nociceptive hypersensitivity.Fórmula:C20H21N5OForma y color:SolidPeso molecular:347.41FAAH-IN-8
CAS:FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 of 6.7 nM and a Ki of 5 nM. It exhibits high blood-brain permeability and a significant antioxidant profile without neurotoxicity [1].Fórmula:C18H14N4OForma y color:SolidPeso molecular:302.33FAAH-IN-5
CAS:FAAH-IN-5 (Compound 7) selectively, irreversibly inhibits FAAH (IC50: 10.5 nM) with low PAMPA permeability.Fórmula:C21H19N3O6SForma y color:SolidPeso molecular:441.46URB-694
CAS:URB-694 is a fatty acid amide hydrolase (FAAH) inhibitor.Fórmula:C19H21NO3Forma y color:SolidPeso molecular:311.37MDPD
CAS:MDPD boosts AtFAAH, the enzyme degrading NAEs in Arabidopsis, reducing NAE 12:0's growth inhibition.Fórmula:C21H19N3O3Forma y color:SolidPeso molecular:361.3939Acetylhydrolase-IN-1
CAS:Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).Fórmula:C23H48NO7PPureza:98%Forma y color:SolidPeso molecular:481.6TAK 21d
CAS:Potent FAAH inhibitorFórmula:C19H17F2N7OPureza:98%Forma y color:SolidPeso molecular:397.38JNJ-40413269
CAS:JNJ-40413269 inhibits FAAH, engages central targets, and is effective in rat neuropathic pain.Fórmula:C19H15ClF3N3OForma y color:SolidPeso molecular:393.79FAAH-IN-7
FAAH-IN-7: Reversible FAAH inhibitor, IC50=8.29 nM, reduces oxidative stress, neuroprotective in neuroinflammation.Fórmula:C26H29N3O4Forma y color:SolidPeso molecular:447.53MK-4409
CAS:MK-4409, a potent and selective fatty acid amide hydrolase (FAAH) inhibitor, is being investigated for the treatment of inflammatory and neuropathic pain.Fórmula:C22H17ClFN3O2SPureza:99.58% - 99.87%Forma y color:White SolidPeso molecular:441.91VDM 11
CAS:anandamide transport inhibitorFórmula:C27H39NO2Pureza:98%Forma y color:SolidPeso molecular:409.6OL-135
CAS:OL-135: CNS-accessible, potent, selective FAAH inhibitor with analgesic effects in animals, no motor impairment.Fórmula:C21H22N2O2Forma y color:SolidPeso molecular:334.41
