FAAH
La hidrolasa de amidas de ácidos grasos (FAAH) es una enzima que descompone las amidas de ácidos grasos, incluidos los endocannabinoides como la anandamida. Estos compuestos están involucrados en la regulación del dolor, el estado de ánimo, el apetito y la memoria. La inhibición de la FAAH puede aumentar los niveles de estas moléculas de señalización, ofreciendo beneficios terapéuticos potenciales para el dolor, la ansiedad y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una selección de inhibidores de FAAH para apoyar su investigación en neurociencia, manejo del dolor y señalización endocannabinoide.
Se han encontrado 64 productos de "FAAH"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
N-Benzyllinolenamide
CAS:<p>N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).</p>Fórmula:C25H37NOPureza:98.7% - 99.92%Forma y color:SolidPeso molecular:367.57PF-04457845
CAS:<p>PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM).</p>Fórmula:C23H20F3N5O2Pureza:>99.99%Forma y color:SolidPeso molecular:455.43JNJ-1661010
CAS:<p>JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2.</p>Fórmula:C19H19N5OSPureza:99.79% - 99.97%Forma y color:SolidPeso molecular:365.45BIA 10-2474
CAS:<p>BIA 10-2474 is a long-acting reversible inhibitor of FAAH that increases levels of the neurotransmitter anandamide in the nervous system.</p>Fórmula:C16H20N4O2Pureza:99.27%Forma y color:SolidPeso molecular:300.36URB-597
CAS:<p>URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.</p>Fórmula:C20H22N2O3Pureza:97.20% - 98.24%Forma y color:SolidPeso molecular:338.44-Nonylphenylboronic acid
CAS:<p>4-Nonylphenylboronic acid is a inhibitor of FAAH.</p>Fórmula:C15H25BO2Pureza:97.63%Forma y color:SolidPeso molecular:248.17MAGL-IN-4
CAS:<p>MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.</p>Fórmula:C18H21ClN2O4Pureza:99.79%Forma y color:SolidPeso molecular:364.82N-Benzylpalmitamide
CAS:<p>N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the</p>Fórmula:C23H39NOPureza:97.08% - 99.77%Forma y color:SolidPeso molecular:345.56FAAH-IN-8
CAS:<p>FAAH-IN-8 (compound 11) is a competitive inhibitor of FAAH with an IC50 of 6.7 nM and a Ki of 5 nM. It exhibits high blood-brain permeability and a significant antioxidant profile without neurotoxicity [1].</p>Fórmula:C18H14N4OForma y color:SolidPeso molecular:302.33AKU-005
CAS:<p>AKU-005 is a dual inhibitor of FAAH and MAGL, exhibiting IC50 values of 63 nM and 389 nM against rat and human FAAH, respectively. This compound has potential for researching trigeminal nociceptive hypersensitivity.</p>Fórmula:C20H21N5OForma y color:SolidPeso molecular:347.41JNJ-40413269
CAS:<p>JNJ-40413269 inhibits FAAH, engages central targets, and is effective in rat neuropathic pain.</p>Fórmula:C19H15ClF3N3OForma y color:SolidPeso molecular:393.79SA57
CAS:<p>SA57 is a potent, selective inhibitor of FAAH(IC50s of 3.2 nM and 1.9 nM for mouse and human FAAH).</p>Fórmula:C17H23ClN2O3Pureza:98%Forma y color:SolidPeso molecular:338.83Acetylhydrolase-IN-1
CAS:<p>Acetylhydrolase-IN-1 is an inhibitor of the esterase 1-Alkyl-2-acetylglycerophosphocholine (Alkylacetyl-GPC: acetylhydrolase).</p>Fórmula:C23H48NO7PPureza:98%Forma y color:SolidPeso molecular:481.6OL-135
CAS:<p>OL-135: CNS-accessible, potent, selective FAAH inhibitor with analgesic effects in animals, no motor impairment.</p>Fórmula:C21H22N2O2Forma y color:SolidPeso molecular:334.41FAAH-IN-7
<p>FAAH-IN-7: Reversible FAAH inhibitor, IC50=8.29 nM, reduces oxidative stress, neuroprotective in neuroinflammation.</p>Fórmula:C26H29N3O4Forma y color:SolidPeso molecular:447.53FAAH-IN-5
CAS:<p>FAAH-IN-5 (Compound 7) selectively, irreversibly inhibits FAAH (IC50: 10.5 nM) with low PAMPA permeability.</p>Fórmula:C21H19N3O6SForma y color:SolidPeso molecular:441.46URB-694
CAS:<p>URB-694 is a fatty acid amide hydrolase (FAAH) inhibitor.</p>Fórmula:C19H21NO3Forma y color:SolidPeso molecular:311.37MDPD
CAS:<p>MDPD boosts AtFAAH, the enzyme degrading NAEs in Arabidopsis, reducing NAE 12:0's growth inhibition.</p>Fórmula:C21H19N3O3Forma y color:SolidPeso molecular:361.39TAK 21d
CAS:<p>Potent FAAH inhibitor</p>Fórmula:C19H17F2N7OPureza:98%Forma y color:SolidPeso molecular:397.38Arachidonyl serotonin
CAS:<p>Dual FAAH inhibitor/TRPV1 antagonist</p>Fórmula:C30H42N2O2Pureza:98%Forma y color:SolidPeso molecular:462.67
