PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 164 productos de "PPAR"
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Daltroban
CAS:<p>Daltroban (SKF 96148) is a specific thromboxane A2 (TXA2) receptor antagonist.</p>Fórmula:C16H16ClNO4SPureza:99.74%Forma y color:SolidPeso molecular:353.82GW 9578
CAS:<p>GW 9578 is a PPARα agonist with potent lipid-lowering activity for the study of psoriasis, arthritis, alopecia, asthma and type I diabetes.</p>Fórmula:C26H34F2N2O3SPureza:98%Forma y color:SolidPeso molecular:492.62ARH-049020
CAS:<p>ARH-049020, a peroxisome proliferator-activated receptor (PPAR) agonist, is used potentially for the treatment of insulin resistance and type 2 diabetes.</p>Fórmula:C24H31NO6Pureza:97.19% - 99.82%Forma y color:SolidPeso molecular:429.51Reglitazar
CAS:<p>Reglitazar, a dual PPARα/γ agonist, enhances insulin signaling, reduces insulin resistance, and lowers hypertriglyceridemia in obese rats.</p>Fórmula:C22H20N2O5Pureza:97.07% - 98.72%Forma y color:SolidPeso molecular:392.4THR-0921
CAS:<p>THR-0921 (CLX-0921) is a peroxisome proliferator-activated receptor (PPAR) agonist that can be used to study cardiovascular and metabolic diseases.</p>Fórmula:C28H25NO7SPureza:100% - 99.83%Forma y color:SolidPeso molecular:519.57AVE-8134
CAS:<p>AVE-8134 is an agonist of PPARα. For human and rodent PPARα receptor, the EC50 values are 100 and 3000 nM, respectively.</p>Fórmula:C22H23NO5Pureza:98%Forma y color:SolidPeso molecular:381.42PPARα-MO-1
CAS:<p>PPARα-MO-1 is a potent modulator of PPARα.</p>Fórmula:C27H37NO5Pureza:98%Forma y color:SolidPeso molecular:455.59LG100754
CAS:<p>LG100754 (UVI 2112) is an insulin sensitizer and RXR modulator, antagonizing RXR homodimers while agonizing RXR:PPARα/γ heterodimers.</p>Fórmula:C26H36O3Forma y color:SolidPeso molecular:396.56Chiglitazar
CAS:<p>Chiglitazar is a PPAR α/γ/δ agonist and insulin sensitizer used in the treatment of type 2 diabetes mellitus , anti-inflammatory and anti-fibrotic.</p>Fórmula:C36H29FN2O4Forma y color:SolidPeso molecular:572.63Inolitazone dihydrochloride
CAS:<p>Inolitazone dihydrochloride is an effective, high-affinity PPARγ agonist; its biological activity is dependent on PPARγ (IC50:0.8 nM) to inhibit cell growth.</p>Fórmula:C27H28Cl2N4O4SForma y color:SolidPeso molecular:575.51Saroglitazar
CAS:<p>Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.</p>Fórmula:C25H29NO4SPureza:98.51%Forma y color:SolidPeso molecular:439.57GSK376501A
CAS:<p>GSK376501A is a selective and effective modulator of peroxisome proliferator-activated receptor γ (PPARγ) for the study of type 2 diabetes.</p>Fórmula:C32H37NO6Pureza:>99.99%Forma y color:SolidPeso molecular:531.64Indeglitazar
CAS:<p>Indeglitazar (PPM 204) is orally available pan-agonist of PPAR (PPAR subtypes alpha (α), delta (δ), and gamma (γ)).</p>Fórmula:C19H19NO6SPureza:99.45%Forma y color:SolidPeso molecular:389.42K-111
CAS:<p>K-111 is a PPAR alpha agonist. K-111 improves insulin resistance, reducing bodyweight, and ameliorating atherogenic dyslipidemia.</p>Fórmula:C18H25Cl3O2Pureza:99.64% - 99.88%Forma y color:SolidPeso molecular:379.75Farglitazar
CAS:<p>Farglitazar (GI-262570) is a PPAR-γ agonist and insulin sensitizer used in the study of diabetes.</p>Fórmula:C34H30N2O5Pureza:99.4% - 99.52%Forma y color:SolidPeso molecular:546.61Cevoglitazar
CAS:<p>Cevoglitazar (LBM-642) is a PPARɑ agonist and PPARγ agonist. Cevoglitazar potently reduces food intake and body weight in obese mice and cynomolgus monkeys.</p>Fórmula:C27H21F3N2O6SPureza:98.75%Forma y color:SolidPeso molecular:558.53Dazmegrel
CAS:<p>Dazmegrel (UK 38,485) is a thromboxane A2 (TXA2) synthase inhibitor for the prevention of increased whole platelet aggregation in normal pregnancy.</p>Fórmula:C16H17N3O2Pureza:98.81%Forma y color:SolidPeso molecular:283.33BAY-0069
CAS:<p>BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be</p>Fórmula:C22H16BrN3O4Pureza:99.41%Forma y color:SoildPeso molecular:466.28Linotroban
CAS:<p>Linotroban（CL-871502） is a potent selective thromboxane (TXA2) receptor antagonist with antithrombotic activity.</p>Fórmula:C14H15NO5S2Pureza:97.95% - >99.99%Forma y color:SolidPeso molecular:341.4BAY-4931
CAS:<p>BAY-4931 is a powerful, covalent, and selective inverse-agonist of PPARγ, exhibiting an IC50 value of 0.17 nM.</p>Fórmula:C22H16ClN3O4Pureza:99.47%Forma y color:SoildPeso molecular:421.83
