PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 170 productos de "PPAR"
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GW590735
CAS:GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.Fórmula:C23H21F3N2O4SPureza:99.53%Forma y color:SolidPeso molecular:478.48GQ-16
CAS:GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.Fórmula:C19H16BrNO3SPureza:99.84%Forma y color:SolidPeso molecular:418.3Ref: TM-T21955
10mg39,00€25mg80,00€50mg116,00€100mg187,00€200mg280,00€500mg449,00€1mL*10mM (DMSO)35,00€Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Fórmula:C20H17N3O4SPureza:99.74%Forma y color:SolidPeso molecular:395.43CP-868388 free base
CAS:CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.Fórmula:C26H33NO5Pureza:99.84%Forma y color:SolidPeso molecular:439.54PPAR α/PPARA Protein, Mouse, Recombinant (His)
PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:31.49 kDa (predicted)Ref: TM-TMPY-06837
5µg109,00€10µg174,00€20µg289,00€50µg576,00€100µg1.017,00€200µg1.718,00€500µg4.207,00€PPAR α/PPARA Protein, Human, Recombinant (His)
PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:31.36 kDa (predicted)Ref: TM-TMPY-06830
5µg110,00€10µg177,00€20µg289,00€50µg576,00€100µg1.007,00€200µg1.700,00€500µg3.631,00€SR 16832
CAS:SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.Fórmula:C17H12ClN3O4Pureza:99.6%Forma y color:SolidPeso molecular:357.75GW0742
CAS:GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).Fórmula:C21H17F4NO3S2Pureza:99.75% - 99.85%Forma y color:SolidPeso molecular:471.49CDDO-Im
CAS:CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).Fórmula:C34H43N3O3Pureza:98.3% - 99.61%Forma y color:SolidPeso molecular:541.72Ref: TM-TQ0120
1mg34,00€5mg74,00€10mg105,00€25mg200,00€50mg319,00€100mg485,00€500mg1.035,00€1mL*10mM (DMSO)89,00€Angeloylgomisin H
CAS:Angeloylgomisin H shows moderate cytotoxic activities with IC50 values ranging from 100 to 200 ug/mL against MCF7, HEK293 and CAL27 cell lines.Fórmula:C28H36O8Pureza:99.84% - 99.95%Forma y color:SolidPeso molecular:500.58Ref: TM-TN1018
1mg52,00€5mg111,00€10mg172,00€25mg290,00€50mg420,00€100mg577,00€1mL*10mM (DMSO)149,00€Cinnamyl alcohol
CAS:Cinnamyl alcohol (Styryl Carbinol) readily autoxidizes upon air exposure, and forms strong sensitizers as determined by the local lymph node assay.Fórmula:C9H10OPureza:99.00%Forma y color:Colourless LiquidPeso molecular:134.18SC-236
CAS:SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).Fórmula:C16H11ClF3N3O2SPureza:99.74%Forma y color:SolidPeso molecular:401.79Clofibrate
CAS:Clofibrate (Clofibrato) is an aryloxyisobutyric acid derivate with antihyperlipidemic activity.Fórmula:C12H15ClO3Pureza:98.77%Forma y color:Oil LiquidPeso molecular:242.70Raspberry ketone
CAS:1.Fórmula:C10H12O2Pureza:99.84% - 99.89%Forma y color:White Solid CrystallinePeso molecular:164.2Fisetin
CAS:Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.Fórmula:C15H10O6Pureza:94.14% - 99.05%Forma y color:Yellow To Brown Crystalline PowderPeso molecular:286.24Ginsenoside Rh1
CAS:Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.Fórmula:C36H62O9Pureza:99% - 99.64%Forma y color:SolidPeso molecular:638.87Alpinetin
CAS:Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & activates caspases.Fórmula:C16H14O4Pureza:98.39%Forma y color:SolidPeso molecular:270.28Oleuropein
CAS:Oleuropein is an antioxidant polyphenol isolated from olive leaf.Fórmula:C25H32O13Pureza:98% - 99.95%Forma y color:Brown PowderPeso molecular:540.51EPI-001
CAS:EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ～6 μM and a selective PPAR-gamma modulator.Fórmula:C21H27ClO5Pureza:99% - 99.67%Forma y color:SolidPeso molecular:394.89Ref: TM-T6829
2mg34,00€5mg48,00€10mg73,00€25mg120,00€50mg192,00€100mg286,00€200mg425,00€1mL*10mM (DMSO)49,00€Glabridin
CAS:Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.Fórmula:C20H20O4Pureza:99.78% - 99.99%Forma y color:Light Yellow Powder Insoluble In WaterPeso molecular:324.37Convallatoxin
CAS:Convallatoxin is a natural product.Fórmula:C29H42O10Pureza:99.27% - 99.53%Forma y color:Prisms From Methanol + Ether SolidPeso molecular:550.64Elafibranor
CAS:Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) withFórmula:C22H24O4SPureza:98.42% - 98.78%Forma y color:SolidPeso molecular:384.49Ref: TM-T4408
2mg34,00€5mg50,00€10mg66,00€25mg104,00€50mg167,00€100mg268,00€200mg404,00€1mL*10mM (DMSO)54,00€Methyl oleanonate
CAS:3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.Fórmula:C31H48O3Pureza:98.99%Forma y color:SolidPeso molecular:468.71Gypenoside XLIX
CAS:Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry conditionFórmula:C52H86O21Pureza:97.05% - 99.78%Forma y color:SolidPeso molecular:1047.23NPC 15199
CAS:NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.
Fórmula:C21H23NO4Pureza:99.93% - 99.94%Forma y color:White Crystalline PowderPeso molecular:353.41AMG131
CAS:AMG131 (CHS 131) , is a novel, non-thiazolidinedione (TZD), selective peroxisome proliferator-activated receptor (PPAR)gamma modulator, which can be used forFórmula:C21H12Cl4N2O3SPureza:99.37%Forma y color:SolidPeso molecular:514.21MK-886
CAS:MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).Fórmula:C27H34ClNO2SPureza:99.23% - 99.84%Forma y color:SolidPeso molecular:472.08Ref: TM-T6893
1mg35,00€5mg70,00€10mg111,00€25mg216,00€50mg354,00€100mg540,00€200mg772,00€1mL*10mM (DMSO)72,00€BMS-687453
CAS:BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgammaFórmula:C22H21ClN2O6Pureza:99.4%Forma y color:SolidPeso molecular:444.86Ref: TM-T5532
1mg44,00€2mg57,00€5mg93,00€10mg137,00€25mg268,00€50mg409,00€100mg620,00€1mL*10mM (DMSO)92,00€Oroxin A
CAS:Oroxin A (Baicalein 7-O-glucoside) has antitussive and expectorant effects.Fórmula:C21H20O10Pureza:98.05% - 99.74%Forma y color:SolidPeso molecular:432.38Ref: TM-T5S0788
1mg40,00€5mg82,00€10mg128,00€25mg210,00€50mg330,00€100mg480,00€200mg682,00€1mL*10mM (DMSO)90,00€G3335 Acetate
G3335 Acetate was discovered to be a novel PPARgamma antagonist.Fórmula:C18H23N3O7Pureza:99.75%Forma y color:SolidPeso molecular:393.39Ref: TM-T21598L
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)79,00€LJ570
CAS:LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)Fórmula:C27H22O3Pureza:99.64%Forma y color:SolidPeso molecular:394.46Ref: TM-T8374
1mg138,00€2mg202,00€5mg311,00€10mg445,00€25mg680,00€50mg888,00€100mg1.234,00€500mg2.475,00€1mL*10mM (DMSO)334,00€Ciprofibrate
CAS:Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.Fórmula:C13H14Cl2O3Pureza:99.63% - >99.99%Forma y color:White Or Almost White Crystalline PowderPeso molecular:289.15L-165041
CAS:L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)Fórmula:C22H26O7Pureza:97.97%Forma y color:SolidPeso molecular:402.44GSK0660
CAS:GSK0660 is an antagonist and inverse agonist of PPARβ/δ.Fórmula:C19H18N2O5S2Pureza:99.26% - ≥95%Forma y color:SolidPeso molecular:418.49Ref: TM-T2674
2mg44,00€5mg65,00€10mg99,00€25mg175,00€50mg349,00€100mg520,00€500mg1.134,00€1mL*10mM (DMSO)65,00€OPHIOPOGONIN D
CAS:Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.Fórmula:C44H70O16Pureza:99.46% - ≥95%Forma y color:SolidPeso molecular:855.02XMD8-87
CAS:XMD8-87 (ACK1-B19), a TNK2 inhibitor, strongly blocks TNK2 phosphorylation and mutations in tumors.Fórmula:C24H27N7O2Pureza:98.05% - 99.89%Forma y color:SolidPeso molecular:445.52Ref: TM-T3709
2mg44,00€5mg70,00€10mg98,00€25mg178,00€50mg290,00€100mg480,00€500mg1.161,00€1mL*10mM (DMSO)84,00€GW 501516
CAS:GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.Fórmula:C21H18F3NO3S2Pureza:98.91% - 99.64%Forma y color:White SolidPeso molecular:453.50XMD16-5
CAS:XMD16-5 blocks TNK2, linked to advanced lung/prostate cancers and breast cancer metastasis in mice; disrupts signaling in several tumors.Fórmula:C23H24N6O2Pureza:98.89% - 99.98%Forma y color:SolidPeso molecular:416.48Ref: TM-T3710
1mg42,00€2mg52,00€5mg95,00€10mg137,00€25mg213,00€50mg394,00€100mg583,00€500mg1.243,00€1mL*10mM (DMSO)95,00€Astaxanthin
CAS:Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.
Fórmula:C40H52O4Pureza:95.1% - 99.79%Forma y color:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Agrimol B
CAS:1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.Fórmula:C37H46O12Pureza:99.06% - ≥95%Forma y color:SolidPeso molecular:682.75(E/Z)-Elafibranor
CAS:GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.Fórmula:C22H24O4SPureza:98.36%Forma y color:SolidPeso molecular:384.49Ref: TM-T8699
2mg35,00€5mg52,00€10mg66,00€25mg104,00€50mg167,00€100mg259,00€200mg388,00€1mL*10mM (DMSO)54,00€Avicularin
CAS:Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.Fórmula:C20H18O11Pureza:97.02% - 99.94%Forma y color:White PowderPeso molecular:434.35Ref: TM-T6S0117
1mg55,00€5mg92,00€10mg152,00€25mg268,00€50mg395,00€100mg583,00€200mg832,00€1mL*10mM (DMSO)105,00€Bilobetin
CAS:Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.Fórmula:C31H20O10Pureza:97% - 99.69%Forma y color:SolidPeso molecular:552.48Ref: TM-T4S2128
1mg44,00€2mg66,00€5mg137,00€10mg236,00€25mg403,00€50mg582,00€100mg800,00€1mL*10mM (DMSO)177,00€Choline Fenofibrate
CAS:Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic
Fórmula:C22H28ClNO5Pureza:98.82%Forma y color:SolidPeso molecular:421.91Pirinixic Acid
CAS:Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.Fórmula:C14H14ClN3O2SPureza:98.27% - 99.92%Forma y color:SolidPeso molecular:323.8Ref: TM-T2269
1g350,00€10mg48,00€25mg64,00€50mg79,00€100mg105,00€200mg148,00€500mg236,00€1mL*10mM (DMSO)47,00€Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Forma y color:SolidPeso molecular:274.36Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Forma y color:SolidPeso molecular:393.89GW1929
CAS:GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).
Fórmula:C30H29N3O4Pureza:98.1% - 98.21%Forma y color:SolidPeso molecular:495.57GSK3787
CAS:GSK3787 is a specific and irreversible PPARδ inhibitor（pIC50= 6.6）.Fórmula:C15H12ClF3N2O3SPureza:98% - 99.56%Forma y color:SolidPeso molecular:392.78Ref: TM-T1941
5mg52,00€10mg82,00€25mg170,00€50mg293,00€100mg494,00€500mg1.054,00€1mL*10mM (DMSO)52,00€Bocidelpar
CAS:Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.Fórmula:C25H27F3N2O3Pureza:97.77%Forma y color:SolidPeso molecular:460.49Ref: TM-T39516
1mg114,00€5mg260,00€10mg389,00€25mg703,00€50mg1.054,00€100mg1.468,00€1mL*10mM (DMSO)264,00€
