PPAR
Los receptores activados por proliferadores de peroxisomas (PPARs) son un grupo de proteínas receptoras nucleares que funcionan como factores de transcripción regulando la expresión de genes involucrados en el metabolismo, particularmente en el almacenamiento de ácidos grasos y el metabolismo de la glucosa. Los inhibidores de PPAR son herramientas importantes para estudiar trastornos metabólicos como la diabetes, la obesidad y las enfermedades cardiovasculares. Estos inhibidores pueden modular el metabolismo de los lípidos, la sensibilidad a la insulina y la inflamación, lo que los convierte en valiosos en la investigación terapéutica. En CymitQuimica, ofrecemos una gama de inhibidores de PPAR para apoyar su investigación en enfermedades metabólicas, endocrinología y desarrollo de fármacos.
Se han encontrado 164 productos de "PPAR"
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GW590735
CAS:<p>GW590735: PPARα agonist, EC50=4 nM, >500x selective over PPARδ/γ, for dyslipidemia research.</p>Fórmula:C23H21F3N2O4SPureza:99.53%Forma y color:SolidPeso molecular:478.48PPARγ-IN-3
<p>PPARγ-IN-3 (compound 9ga), a potent and orally active PPARγ inhibitor, effectively reduces triglyceride (TG) accumulation and exhibits low cytotoxicity. Additionally, it prevents excessive body weight gain, lessens fat and liver mass, and decreases lipid accumulation in both the liver and blood. PPARγ-IN-3 holds promise for research into diet-induced obesity.</p>Fórmula:C23H28FN7O3Forma y color:SolidPeso molecular:469.51GQ-16
CAS:<p>GQ-16 is a partial agonist of PPARγ with a Ki of 160 nM. GQ-16 reduces adipogenic actions and promotes insulin Sensitization without weight gain.</p>Fórmula:C19H16BrNO3SPureza:99.84%Forma y color:SolidPeso molecular:418.3CP-868388 free base
CAS:<p>CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.</p>Fórmula:C26H33NO5Pureza:99.84%Forma y color:SolidPeso molecular:439.54PPAR α/PPARA Protein, Human, Recombinant (His)
<p>PPAR alpha/PPARA Protein, Human, Recombinant (His) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:31.36 kDa (predicted)PPAR α/PPARA Protein, Mouse, Recombinant (His)
<p>PPAR alpha/PPARA Protein, Mouse, Recombinant (His) is expressed in E.</p>Forma y color:Lyophilized PowderPeso molecular:31.49 kDa (predicted)Balaglitazone
CAS:<p>Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.</p>Fórmula:C20H17N3O4SPureza:99.74%Forma y color:SolidPeso molecular:395.43Ciprofibrate
CAS:<p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>Fórmula:C13H14Cl2O3Pureza:99.63% - >99.99%Forma y color:White Or Almost White Crystalline PowderPeso molecular:289.15Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Fórmula:C20H18O11Pureza:97.02% - 99.94%Forma y color:White PowderPeso molecular:434.35MK-886
CAS:<p>MK-886 (L 663536) is an inhibitor of leukotriene biosynthesis, inhibiting 5-lipoxygenase-activating protein (FLAP).</p>Fórmula:C27H34ClNO2SPureza:99.23% - 99.84%Forma y color:SolidPeso molecular:472.08LJ570
CAS:<p>LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[)</p>Fórmula:C27H22O3Pureza:99.64%Forma y color:SolidPeso molecular:394.46Choline Fenofibrate
CAS:<p>Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemic</p>Fórmula:C22H28ClNO5Pureza:98.82%Forma y color:SolidPeso molecular:421.91Rosiglitazone
CAS:<p>Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.</p>Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Forma y color:White To Off-White Crystalline PowderPeso molecular:357.43NPC 15199
CAS:<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Fórmula:C21H23NO4Pureza:99.93% - 99.94%Forma y color:White Crystalline PowderPeso molecular:353.41Seladelpar
CAS:<p>Seladelpar (MBX 8025) has been used in trials studying the treatment of Hyperlipidemia.</p>Fórmula:C21H23F3O5SPureza:99.18% - 99.41%Forma y color:SolidPeso molecular:444.46Norathyriol
CAS:<p>Norathyriol is a potent PTP1B inhibitor with good cell permeability and oral availability.</p>Fórmula:C13H8O6Pureza:99.35% - 99.55%Forma y color:SolidPeso molecular:260.2Pirinixic Acid
CAS:<p>Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.</p>Fórmula:C14H14ClN3O2SPureza:98.27% - 99.92%Forma y color:SolidPeso molecular:323.8Bilobetin
CAS:<p>Bilobetin ameliorates insulin resistance by PKA-mediated phosphorylation of PPARα in rats fed a high-fat diet.</p>Fórmula:C31H20O10Pureza:97.74% - 99.69%Forma y color:SolidPeso molecular:552.48GW 501516
CAS:<p>GW 501516 (Endurobol) is a effective and highly specifc PPARβ/δ agonist (EC50: 1 nM), with 1000-fold selectivity over hPPARα/γ.</p>Fórmula:C21H18F3NO3S2Pureza:98.91% - 99.64%Forma y color:White SolidPeso molecular:453.50OPHIOPOGONIN D
CAS:<p>Ophiopogonin D is a natural product,and is a CYP2J3 inducer that significantly inhibits Ang II induced NF-κB nuclear translocation.</p>Fórmula:C44H70O16Pureza:99.46% - ≥95%Forma y color:SolidPeso molecular:855.02BMS-687453
CAS:<p>BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma</p>Fórmula:C22H21ClN2O6Pureza:99.4%Forma y color:SolidPeso molecular:444.86Licarin B
CAS:<p>1.(-)-Licarin B (Licarine B) has anti-mycobacterial activity.</p>Fórmula:C20H20O4Pureza:99.82% - ≥95%Forma y color:SolidPeso molecular:324.37Eupatilin
CAS:<p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>Fórmula:C18H16O7Pureza:98.53% - 99%Forma y color:SolidPeso molecular:344.32GW9662
CAS:<p>GW9662 (TIMTEC-BB SBB006523) is a PPARγ antagonist (IC50=3.3 nM) with selectivity. GW9662 has anti-tumor effect. High-Quality, Low-Cost!</p>Fórmula:C13H9ClN2O3Pureza:98% - 99.95%Forma y color:Off-White SolidPeso molecular:276.68SR1664
CAS:<p>SR1664 is a potent and selective PPARγ inhibitor with potential antidiabetic activity.</p>Fórmula:C33H29N3O5Pureza:98.02%Forma y color:SolidPeso molecular:547.6FH535
CAS:<p>FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.</p>Fórmula:C13H10Cl2N2O4SPureza:98.25% - 99.5%Forma y color:SolidPeso molecular:361.2Icariin
CAS:<p>Icariin (Ieariline) is a flavonol glycoside that inhibits PDE5 and PDE4 activity and is a PPARα activator. Cost-effective and quality-assured.</p>Fórmula:C33H40O15Pureza:97.82% - 98.3%Forma y color:SolidPeso molecular:676.66Glabrone
CAS:<p>Glabrone shows antiviral activity against influenza virus.</p>Fórmula:C20H16O5Pureza:99.08% - 99.55%Forma y color:SolidPeso molecular:336.34GW6471
CAS:<p>GW6471 is an antagonist of PPARα. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR.</p>Fórmula:C35H36F3N3O4Pureza:98.23% - 99.55%Forma y color:SolidPeso molecular:619.67Palmitelaidic Acid
CAS:<p>Palmitelaidic Acid (trans-Palmitoleic acid) is one of the most abundant fatty acids in serum and tissue.</p>Fórmula:C16H30O2Pureza:99.76%Forma y color:SolidPeso molecular:254.41NSC-87877 disodium
CAS:<p>NSC-87877 disodium (NSC87877) is a cell-permeable inhibitor of both SHP-1 and SHP-2. NSC-87877 also inhibits EGF-induced Erk1/2 activation in HEK293 cells.</p>Fórmula:C19H13N3O7S2·2NaPureza:97.89%Forma y color:SolidPeso molecular:503.42SR 16832
CAS:<p>SR 16832: Dual-site PPARγ inhibitor; outperforms GW 9662, T 0070907 in ligand binding, transcription inhibition.</p>Fórmula:C17H12ClN3O4Pureza:99.6%Forma y color:SolidPeso molecular:357.75GW0742
CAS:<p>GW0742 (GW610742) is an effective and specific PPARδ agonist (EC50: 1 nM/1.1 μM/2 μM, for human PPARδ/α/γ).</p>Fórmula:C21H17F4NO3S2Pureza:99.75% - 99.85%Forma y color:SolidPeso molecular:471.49CDDO-Im
CAS:<p>CDDO-Im (TP-235) is an activator of Nrf2 and PPAR (Kis: 232/344 nM for PPARα/PPARγ).</p>Fórmula:C34H43N3O3Pureza:98.3% - 99.61%Forma y color:SolidPeso molecular:541.72SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Fórmula:C16H11ClF3N3O2SPureza:99.74%Forma y color:SolidPeso molecular:401.79Raspberry ketone
CAS:<p>1.</p>Fórmula:C10H12O2Pureza:99.84% - 99.89%Forma y color:White Solid CrystallinePeso molecular:164.2Fisetin
CAS:<p>Fisetin belongs to a group of natural flavonols with anti-inflammatory, antioxidant, anti-tumor, anti-aging and neuroprotective effects. Cost effective and quality assured.</p>Fórmula:C15H10O6Pureza:94.14% - 99.05%Forma y color:Yellow To Brown Crystalline PowderPeso molecular:286.24Ginsenoside Rh1
CAS:<p>Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.</p>Fórmula:C36H62O9Pureza:99% - 99.77%Forma y color:SolidPeso molecular:638.87Alpinetin
CAS:<p>Alpinetin: antibacterial, anti-inflammatory, boosts HepG2 sensitivity to CDDP, fights hepatoma/pancreatic cancer, inhibits cell growth & activates caspases.</p>Fórmula:C16H14O4Pureza:98.39%Forma y color:SolidPeso molecular:270.28Glabridin
CAS:<p>Glabridin aids in diabetes by reducing inflammation and glucose levels and may prevent liver cancer spread.</p>Fórmula:C20H20O4Pureza:99.78% - 99.99%Forma y color:Light Yellow Powder Insoluble In WaterPeso molecular:324.37Convallatoxin
CAS:<p>Convallatoxin is a natural product.</p>Fórmula:C29H42O10Pureza:99.27% - 99.53%Forma y color:Prisms From Methanol + Ether SolidPeso molecular:550.64Methyl oleanonate
CAS:<p>3-Oxoolean-12-en-28-oic acid methyl ester is a triterpenoid PPARγ agonist isolated from Pistacia with anticancer properties.</p>Fórmula:C31H48O3Pureza:98.99%Forma y color:SolidPeso molecular:468.71Astaxanthin
CAS:<p>Astaxanthin, a keto-carotenoid and xanthophyll, offers antioxidant benefits, present in red aquatic species, and used as a colorant in animal feed.</p>Fórmula:C40H52O4Pureza:95.1% - 99.79%Forma y color:Needles From Acetone/Light Petroleum SolidPeso molecular:596.84Agrimol B
CAS:<p>1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.</p>Fórmula:C37H46O12Pureza:99.06% - ≥95%Forma y color:SolidPeso molecular:682.75(E/Z)-Elafibranor
CAS:<p>GFT505 (Elafibranor) (Elafibranor) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively.</p>Fórmula:C22H24O4SPureza:98.36%Forma y color:SolidPeso molecular:384.49Adelmidrol
CAS:<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Forma y color:SolidPeso molecular:274.36GW1929
CAS:<p>GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ).</p>Fórmula:C30H29N3O4Pureza:98.1% - 98.21%Forma y color:SolidPeso molecular:495.57Bocidelpar
CAS:<p>Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells.</p>Fórmula:C25H27F3N2O3Pureza:97.77%Forma y color:SolidPeso molecular:460.49Troglitazone
CAS:<p>Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.</p>Fórmula:C24H27NO5SPureza:98% - 99.8%Forma y color:Yellow SolidPeso molecular:441.54Tetradecylthioacetic acid
CAS:<p>Synthetic fatty acid TTA has β-sulfur, resists β-oxidation, and activates PPARs, especially PPARα.</p>Fórmula:C16H32O2SPureza:99.93%Forma y color:SolidPeso molecular:288.49
