HMG-CoA reductasa
La HMG-CoA Reductasa es una enzima clave en la vía del mevalonato, responsable de la síntesis de colesterol y otros isoprenoides. Los inhibidores de la HMG-CoA reductasa, comúnmente conocidos como estatinas, se utilizan ampliamente para reducir los niveles de colesterol y disminuir el riesgo de enfermedades cardiovasculares. Estos inhibidores también tienen beneficios potenciales en la investigación sobre el cáncer y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una variedad de inhibidores de la HMG-CoA reductasa para apoyar su investigación en el metabolismo lipídico, la salud cardiovascular y el desarrollo terapéutico.
Se han encontrado 35 productos para "HMG-CoA reductasa".
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(3S,5R)-Pitavastatin calcium
CAS:(3S,5R)-Pitavastatin calcium is the enantiomer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Fórmula:C25H26CaFNO4Pureza:98%Forma y color:SolidPeso molecular:463.562(3S,5S)-Pitavastatin calcium
CAS:(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.Fórmula:C25H26CaFNO4Pureza:98%Forma y color:SolidPeso molecular:463.562Simvastatin acid calcium hydrate
CAS:Simvastatin (Tenivastatin) calcium hydrate is an oral HMG-CoA reductase inhibitor that reduces ROS by blocking indoxyl sulfate.Fórmula:C25H40O6Forma y color:SolidPeso molecular:436.28249L 669262
CAS:L 669262 is a potent inhibitor of HMG-CoA reductase.Fórmula:C25H36O6Forma y color:SolidPeso molecular:432.552'-Ethyl Simvastatin
CAS:2'-Ethyl Simvastatin is a Mevinolin analog that competitively inhibits HMG-CoA reductase for lipid-lowering research.Fórmula:C23H34O5Pureza:97.12%Forma y color:SolidPeso molecular:390.51Crilvastatin
CAS:Crilvastatin (PMD 387) is an HMGCR inhibitor with cholesterol-lowering activity that inhibits cholesterol uptake in rats with hereditary hypercholesterolemia.Fórmula:C14H23NO3Pureza:98.69% - 99.54%Forma y color:SolidPeso molecular:253.344-Acetylsimvastatin
CAS:4-Acetylsimvastatin is acetylated simvastatin. Simvastatin is a competitive inhibitor of HMG-CoA reductase (Ki: 0.2 nM).Fórmula:C27H40O6Pureza:98%Forma y color:SolidPeso molecular:460.6Lovastatin hydroxy acid sodium
CAS:Lovastatin hydroxy acid sodium (Mevinolinic acid sodium) is a competitive inhibitor of HMG-CoA reductase with a Ki value of 0.6 nM, which can lower cholesterol.Fórmula:C24H37NaO6Pureza:99.92%Forma y color:White SolidPeso molecular:444.54(Z)-Pitavastatin calcium
CAS:(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase.Fórmula:C50H50CaF2N2O8Pureza:98%Forma y color:SolidPeso molecular:885.031Dalvastatin
CAS:Dalvastatin (RG-12561) is an orally available inhibitor of HMG-CoA reductase and cholesterol-lowering synthesis.Dalvastatin competitively inhibits rat hepaticFórmula:C24H31FO3Pureza:98.07%Forma y color:Yellow OilPeso molecular:386.5(3R,5R)-Rosuvastatin calcium
CAS:(3R,5R)-Rosuvastatin, a potential impurity detected in bulk rosuvastatin formulations, arises as a degradation product through various stresses including acid or base hydrolysis, thermal, photolytic, hydrolytic, oxidative stress, or during storage. This compound is associated with the HMG-CoA reductase inhibitor class to which rosuvastatin belongs.Fórmula:C22H28FN3O6SCaForma y color:SolidPeso molecular:500.6Rosuvastatin zinc salt
CAS:Rosuvastatin zinc salt (Rosuvastatin zinc), a zinc-infused variant of Rosuvastatin, functions as an HMG-CoA reductase inhibitor, utilized primarily inFórmula:C44H54F2N6O12S2ZnForma y color:SolidPeso molecular:1026.47Bemfivastatin hemicalcium
CAS:Bemfivastatin hemicalcium (PPD 10558), an orally active HMG-CoA reductase inhibitor, serves as a lipid-lowering agent.Fórmula:C34H36FN2O6CaForma y color:SolidPeso molecular:607.67QH536
CAS:QH536 degrades HMGCR (EC50: 0.22 μM), has anti-inflammatory properties, and avoids cholesterol buildup; useful for cardiovascular and NASH research.Fórmula:C33H49N3O3Forma y color:SolidPeso molecular:535.76L 668411
CAS:L 668411, the 2,3-ditritiated methyl ester of L 659699, inhibits HMG-CoA synthase.Fórmula:C19H30O5Pureza:98%Forma y color:SolidPeso molecular:338.44
