Transferasa

PF-06424439 methanesulfonate is an oral, potent and selective imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) inhibitor(IC50 of …

Risedronic acid (Risedronate ), a pyridinyl biphosphonate, can inhibit osteoclast-mediated bone resorption.

Risedronate sodium is an aminobisphosphonate derivative of etidronic acid and CALCIUM CHANNEL BLOCKER that inhibits …

Flopropione, a spasmolytic or antispasmodic agent, is used as a 5-HT1A receptor antagonist.

Opicapone reduces the ATP content of the cells (IC50: 98 μM). Opicapone is an effective …

Ibandronate Sodium is a synthetic nitrogen-containing bisphosphonate, used for the treatment of osteoporosis.

Nialamide is an MAO inhibitor that is used as an antidepressive agent.

7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± …

Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 …

Testosterone Propionate is a short acting oil-based injectable formulation of testosterone. Testosterone inhibits gonadotropin secretion …

Ibiglustat (L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase. Ibiglustat (L-Malic …

JNJ-DGAT2-A, a specific inhibitor of DGAT2(IC50 = 0.14 μM), can be used in studies about …

GGTI 298 is a geranylgeranyltransferase I inhibitor with ability to arrest human tumor cells in …

DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor; anti-obesity drug. Objective: DGAT-1 acyl-CoA: diacylglycerol acyltransferase …

3-O-Methyltolcapone D7 (Ro 40-7591 D7) is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone (Ro 40-7591) is a …

3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor. Tolcapone …

Tolcapone D7 is a deuterium-labeled Tolcapone. Tolcapone is a selective and orally active inhibitor of …

DGAT1-IN-1 is a potent inhibitor of diacylglycerol O- acyltransferase type 1(DGAT1, IC50 of < 10 nM).

FTI 277 hydrochloride is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this …

Tipifarnib is a nonpeptidomimetic quinolinone with potential antineoplastic activity. Tipifarnib binds to and inhibits the …

Arglabin is a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor, has …

Alendronate is a nitrogen-containing bisphosphonate, which is an effective inhibitor of bone resorption. It is …

Ervogastat is a potent and well-tolerated diacylglycerol acyltransferase 2 inhibitor. Ervogastat reduces steatosis and hepatic …

Serotonin hydrochloride is an endogenous 5-HT receptor agonist, a monoamine neurotransmitter in the CNS, and …

Ibiglustat is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks …

The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 …

Tipifarnib S enantiomer is the S-enantiomer of Tipifarnib. Tipifarnib is a potent and specific farnesyltransferase …

Eliglustat is an oral inhibitor of glucosylceramide synthase which is used in the therapy of …

T-863(DGAT-1 inhibitor) is an orally active, selective and potent DGAT1 (Acyl-CoA:diacylglycerol acyltransferase 1) inhibitor that …

OU749 is a γ-glutamyl transferase (GGT) inhibitor with an intrinsic Ki of 17.6 μM.

Entacapone is a selective and reversible inhibitor of catechol-O-methyltransferase(COMT).

CP-609754 shows selective inhibition of farnesyltransferase.

OSMI-1 inhibits protein O-linked N-acetylglucosamine (O-GlcNAcylation) in several mammalian cell lines without qualitatively altering cell …

5-hydroxytryptamine is a natural product from animals

Miglustat hydrochloride is an inhibitor of glucosylceramide synthase and can be used for studies about …

Entacapone is a selective and reversible inhibitor of catechol-O-methyltransferase (COMT).

FGTI-2734 can prevent membrane localization of KRAS, hence solving KRAS resistance problem and thwarting mutant …

Tectol has anti-plasmodial activity, it as a moderately active growth inhibitor with an IC50 of …

Minodronic acid monohydrate is an farnesyl diphosphate synthase inhibitor that acts as a bone resorption …

Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)

Rosmarinate acid inhibits MAO-A, MAO-B and COMT enzymes with IC50s of 50.1, 184.6 and 26.7 …

OR-486 is an inhibitor of catechol-O-methyl-transferase(COMT) and can be used to prepare the molybdenum (VI)- …

Lonafarnib is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).

Rosmarinic acid has shown to contain antioxidant, anti-inflammatory and antimicrobial activities. Possesses promising physiological actions …

Daporinad is a small molecule inhibitor of nicotinamide phosphoribosyltransferase (NMPRTase), with potential antineoplastic and antiangiogenic …

CI 976 is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a …

A922500 is an inhibitor for human and mouse DGAT-1 with IC50 of 7 nM and …

3-Methoxybenzamide is a competitive inhibitor of poly(ADP-ribose) synthetase.

Tolcapone is a catechol-O-methyltransferase inhibitor used in the therapy of Parkinson disease as adjunctive therapy …

PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of …

Carnitine acetyltransferase is a protein that plays a crucial role in the metabolism of fatty …

AZD3988 is an inhibitor of diacylglycerol acyl transferase-1 (DGAT-1). For human, rat, mouse, the IC50s …

LB42708 is an orally active farnesyltransferase (FTase) inhibitor (IC50: 0.8/1.2/2.0 nM toward H/N/K-ras).

PF-06424439 is an oral and selective inhibitor of imidazopyridine diacylglycerol acyltransferase 2 (DGAT2) (IC50 of …

P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.

GGTI-2418 inhibits GGTase I and FTase activities with IC50s of 9.5 nM and 53 μM, …

GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).