Transferasa
Las transferasas son una gran clase de enzimas que catalizan la transferencia de grupos funcionales, como grupos metilo, glicosilo y fosfato, de una molécula a otra. Los inhibidores de transferasas se utilizan para estudiar una amplia gama de procesos biológicos, incluyendo la transducción de señales, el metabolismo y la expresión génica. Estos inhibidores son herramientas esenciales en áreas de investigación como el cáncer, las enfermedades metabólicas y la epigenética, donde está implicada la disfunción de la actividad de las transferasas. En CymitQuimica, ofrecemos una selección integral de inhibidores de transferasas para apoyar su investigación en enzimología, señalización celular y mecanismos de enfermedad.
Se han encontrado 37 productos para "Transferasa".
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Nitecapone
CAS:Nitecapone is a reversible inhibitor of S-COMT (IC50 values of 300 nM in rat liver)Fórmula:C12H11NO6Pureza:98.39%Forma y color:SolidPeso molecular:265.223-O-Methyltolcapone
CAS:3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone which is a potent COMT inhibitor.Fórmula:C15H13NO5Pureza:98%Forma y color:SolidPeso molecular:287.27PDMP hydrochloride
CAS:PDMP, a glucosylceramide synthase inhibitor with 4 stereoisomers, acts at 0.8μM; D-threo enantiomer also blocks lactosylceramide synthesis.Fórmula:C23H39ClN2O3Forma y color:SolidPeso molecular:427.03P-3FAX-Neu5Ac
CAS:P-3FAX-Neu5Ac is a sialic acid analog and a sialyltransferase inhibitor.Fórmula:C22H30FNO14Pureza:97.08%Forma y color:White SolidPeso molecular:551.47Lucerastat
CAS:Lucerastat（NBDGJ） is an orally available inhibitor of GCS for Fabry disease by reducing harmful substrates.. GCS is a key enzyme in sphingolipid synthesiss.Fórmula:C10H21NO4Pureza:98%Forma y color:White SolidPeso molecular:219.28Prenyl-IN-1
CAS:Prenyl-IN-1 inhibits prenylation selectively, counters oxidative stress in Parkinson's.Fórmula:C28H24ClN5O2Pureza:>99.99%Forma y color:SolidPeso molecular:497.98α-2,3-sialyltransferase-IN-1
CAS:α-2,3-sialyltransferase-IN-1 is a noncompetitive inhibitor of α-2,3-sialyltransferase(IC50 of 6 μM).Fórmula:C28H45NO6Pureza:98% - 98%Forma y color:Transparent LiquidPeso molecular:491.66Lith-O-Asp
CAS:Lith-O-Asp is a sialyltransferase inhibitor; Ki=1.3 μM; reduces sialylation; inhibits cancer cell invasion; metastasis research.Fórmula:C28H45NO6Forma y color:White SolidPeso molecular:491.66Ibiglustat (L-Malic acid)
CAS:Ibiglustat (L-Malic acid) (Ibiglustat L-Malic acid) is a selective, brain-penetrant, and allosteric inhibitor of glucosylceramide synthase.Fórmula:C24H30FN3O7SPureza:99.54%Forma y color:SolidPeso molecular:523.57Ref: TM-T11599
1mg37,00€2mg50,00€5mg96,00€1mL*10mM (DMSO)100,00€10mg128,00€25mg208,00€50mg310,00€100mg444,00€200mg618,00€Miglustat hydrochloride
CAS:Miglustat hydrochloride (N-Butyldeoxynojirimycin hydrochloride) is an inhibitor of glucosylceramide synthase and can be used for studies about Type I GaucherFórmula:C10H22ClNO4Pureza:99.85%Forma y color:SolidPeso molecular:255.74Ref: TM-TQ0155
1mg38,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg245,00€50mg385,00€100mg557,00€200mg790,00€FGTI-2734
CAS:FGTI-2734, a dual FT/GGT-1 inhibitor (IC50: 250/520 nM), blocks KRAS membrane binding and curbs KRAS-driven pancreatic cancer.Fórmula:C26H31FN6O2SPureza:99.69%Forma y color:SolidPeso molecular:510.63Ref: TM-T11282
1mg49,00€5mg113,00€1mL*10mM (DMSO)129,00€10mg178,00€25mg371,00€50mg557,00€100mg792,00€OSMI-1
CAS:OSMI-1: cell-permeable OGT inhibitor, blocks O-GlcNAcylation (IC50: 2.7 μM), no effect on other cell glycans.Fórmula:C28H25N3O6S2Pureza:96.79% - 99.66%Forma y color:White SolidPeso molecular:563.64Glucosylceramide synthase-IN-4
CAS:Glucosylceramide Synthase-IN-4 (compound 12) serves as a potent inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 of 6.8 nM. It demonstrates superior pharmacokinetic properties and robust stability in human hepatocytes. Additionally, this compound is noted for its effective CNS penetration and acceptable PXR selectivity [1].Fórmula:C22H18F5N3O3Forma y color:SolidPeso molecular:467.39PF-07202954
CAS:PF-07202954 is a DGAT2 inhibitor with a long half-life. reduce the triglyceride content in the liver of rats fed with a Western diet, NASH.Fórmula:C22H23FN6O3Pureza:98.99%Forma y color:Yellow SolidPeso molecular:438.45ICMT-IN-55
CAS:ICMT-IN-55 (compound 31) acts as an ICMT inhibitor, exhibiting an IC50 value of 90 nM [1].Fórmula:C22H26F3NO2Forma y color:SolidPeso molecular:393.44BMS-214662 mesylate
CAS:BMS-214662 mesylate is a potent and selective farnesyl transferase inhibitor with an IC50 of 1.35 nM. It exhibits antitumor activity and is applicable in cancer research.Fórmula:C26H27N5O5S3Forma y color:SolidPeso molecular:585.718Darlifarnib
CAS:Darlifarnib (Compound (S)-058) is an inhibitor of farnesyl transferase and geranylgeranyltransferase, with IC50 values of ≤ 10 nM and > 1000 nM, respectively. It exhibits high metabolic stability in human and mouse liver microsomes, with a half-life of over 100 minutes.Fórmula:C29H20N6OForma y color:SolidPeso molecular:468.509
