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FASN-IN-3 is an inhibitor of fatty acid synthase (FASN).

trans-C75 is an enantiomer of C75. C75 is an inhibitor of fatty-acid synthase (FASN).

Trimetazidine dihydrochloride can improve myocardial glucose utilization by inhibiting fatty acid metabolism. Trimetazidine is the …

L(-)-Carnitine is an amino acid derivative. L(-)-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering …

Orlistat is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a …

(-)-Hydroxycitric acid (HCA) can inhibit fat synthesis and reduces food intake, the primary mechanism of …

FASN-IN-2 is a Fatty Acid Synthase (FASN) inhibitor(IC50 of 0.052 μM and an EC50 of …

Pyrazinamide, an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic …

Fasnall HCl is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall …

Isoscoparin is derived from Gentiana algida Pall with antioxidant and anti-adipogenic activities. Isoscoparin can be …

Pinostrobin chalcone is a potent inhibitor of triglyceride accumulation, it can inhibit adipogenesis in 3T3-L1 …

IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM).

Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced …

C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: …

1β-Hydroxy-2-oxopomolic acid inhibits adipocyte differentiation through downregulation of various adipocytokines by blocking PPARγ and C/EBPα …

Dihydrocurcumin is the main metabolite of curcumin, which can reduce fat accumulation and oxidative stress …

UCM05 (G28UCM) is a potent fatty acid synthase ( FASN ) inhibitor that shows activity …

Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the …

FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.

Albaspidin-AP, -PP, -PB inhibit Fatty acid synthase (FAS) with IC50 values ranging from 23.1+/-1.4 to …

Betulin (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the …

A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).

Pedunculoside is extracted from Ilex rotunda Thunb.

TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable …

VY-3-135 is a metastasis inhibitor and an acetyl-​CoA synthetase 2 (ACSS2) modulator.

Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been …

FASN-IN-1 is a fatty acid synthase (FASN) inhibitor.

Lycorine inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter …

TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective …

Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and …

trans-Chalcone is an aromatic ketone that forms the central core for a variety of important …

Fatostatin ia an inhibitor of sterol regulatory element binding protein (SREBP). It impairs the activation …

Rimiducid is a lipid-permeable tacrolimus analogue, homodimerizing an analogue of human protein fkbp12 and binding …

FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and …

Fasnall is a selective FASN inhibitor that acts through its co-factor binding sites. Fasnall shows …

FGH-10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).

1. Pseudoprotodioscin has moderate cytotoxicity.

Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.

1. Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, …

ACSS2 inhibitor is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).

Praeruptorin D is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly …

BI99179 is a potent and selective type I fatty acid synthase (FAS) inhibitor with an …