Ácido graso sintasa
La sintasa de ácidos grasos (FAS) es un complejo multi-enzimático responsable de la síntesis de ácidos grasos de cadena larga. La sobreexpresión de FAS está asociada con varios trastornos metabólicos, incluyendo la obesidad, la diabetes y el cáncer. Inhibir FAS puede reducir la biosíntesis de lípidos e inducir apoptosis en células cancerosas, lo que la convierte en un objetivo prometedor para la terapia contra el cáncer y la investigación de enfermedades metabólicas. En CymitQuimica, ofrecemos una variedad de inhibidores de FAS para apoyar su investigación en oncología, metabolismo y desarrollo terapéutico.
Se han encontrado 32 productos de "Ácido graso sintasa"
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Fas C-Terminal Tripeptide Acetate
<p>Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.</p>Fórmula:C18H33N3O8Pureza:99.12%Forma y color:SolidPeso molecular:419.47HS79
CAS:<p>HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.</p>Fórmula:C19H22N4SPureza:98%Forma y color:SolidPeso molecular:338.47HS80
CAS:<p>HS-80, a Fasnall enantiomer, selectively inhibits FASN, blocking lipid synthesis (IC50: 7.13 μM).</p>Fórmula:C19H22N4SPureza:98%Forma y color:SolidPeso molecular:338.47FASN-IN-5
CAS:<p>FASN-IN-5 is a FASN inhibitor, useful for studying cancer and metabolic diseases.</p>Fórmula:C29H26N4O2Pureza:99.88%Forma y color:SolidPeso molecular:462.54FASN-IN-4
CAS:<p>FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.</p>Fórmula:C26H27N3O4SPureza:98%Forma y color:SolidPeso molecular:477.58C75
CAS:<p>C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).</p>Fórmula:C14H22O4Pureza:98.84% - >99.99%Forma y color:SolidPeso molecular:254.32Malic enzyme inhibitor ME1
CAS:<p>Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.</p>Fórmula:C20H21N3O3Pureza:99.84%Forma y color:SolidPeso molecular:351.4FASN-IN-1
CAS:<p>FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme</p>Fórmula:C18H25N3O3S2Pureza:99.92% - >99.99%Forma y color:SolidPeso molecular:395.54SREBP/SCAP-IN-2
CAS:<p>SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].</p>Fórmula:C27H37ClF2N4OForma y color:SolidPeso molecular:507.06SREBP/SCAP-IN-1
CAS:<p>SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].</p>Fórmula:C28H40F2N4OForma y color:SolidPeso molecular:486.64FAS-IN-1 Tosylate
<p>FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.</p>Fórmula:C33H35N3O7S2Pureza:98%Forma y color:SolidPeso molecular:649.78PFM046
CAS:<p>PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.</p>Fórmula:C29H42O2Forma y color:SolidPeso molecular:422.643
