Ácido graso sintasa
La sintasa de ácidos grasos (FAS) es un complejo multi-enzimático responsable de la síntesis de ácidos grasos de cadena larga. La sobreexpresión de FAS está asociada con varios trastornos metabólicos, incluyendo la obesidad, la diabetes y el cáncer. Inhibir FAS puede reducir la biosíntesis de lípidos e inducir apoptosis en células cancerosas, lo que la convierte en un objetivo prometedor para la terapia contra el cáncer y la investigación de enfermedades metabólicas. En CymitQuimica, ofrecemos una variedad de inhibidores de FAS para apoyar su investigación en oncología, metabolismo y desarrollo terapéutico.
Se han encontrado 40 productos para "Ácido graso sintasa".
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Fatostatin hydrobromide
CAS:Fatostatin hydrobromide (Fatostatin A HBr), an inhibitor of sterol regulatory element binding protein (SREBP), impairs the activation of SREBP-1 and SREBP-2.Fórmula:C18H19BrN2SPureza:98.62% - 99.91%Forma y color:SolidPeso molecular:375.326Ref: TM-T6832
5mg48,00€1mL*10mM (DMSO)50,00€10mg70,00€25mg112,00€50mg182,00€100mg309,00€200mg447,00€500mg747,00€TVB-3664
CAS:TVB-3664 is an orally active, selective, highly bioavailable fatty acid synthase inhibitor (FASN).Cost-effective and quality-assured.Fórmula:C25H23F3N4O2Pureza:99.17% - 99.64%Forma y color:SolidPeso molecular:468.47Ref: TM-T17181
1mg114,00€5mg268,00€1mL*10mM (DMSO)268,00€10mg432,00€25mg708,00€50mg1.044,00€100mg1.423,00€Fas C-Terminal Tripeptide Acetate
Fas C-Terminal Tripeptide Acetate shows inhibitory activity of Fas/FAP-1 binding.Fórmula:C18H33N3O8Pureza:97.85%Forma y color:White SolidPeso molecular:419.47FGH10019
CAS:FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM).Fórmula:C18H19N3O2S2Pureza:98.93%Forma y color:SolidPeso molecular:373.49Ref: TM-T7798
1mg70,00€5mg152,00€1mL*10mM (DMSO)156,00€10mg212,00€25mg355,00€50mg505,00€100mg685,00€200mg888,00€Ac-CoA Synthase Inhibitor1
CAS:Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2).Fórmula:C20H18N4O2S2Pureza:99.26% - 99.84%Forma y color:SolidPeso molecular:410.51Fatostatin
CAS:Fatostatin inhibits SREBP-1/2 by binding to SCAP, blocking their ER-Golgi transport.Fórmula:C18H18N2SPureza:99.77% - 99.92%Forma y color:White SolidPeso molecular:294.414Ref: TM-T9266
2mg34,00€5mg48,00€1mL*10mM (DMSO)50,00€10mg70,00€25mg112,00€50mg182,00€100mg309,00€200mg465,00€Betulin ditosylate
CAS:Betulinditosylate is a derivative of Betulin, which functions as an SREBP inhibitor.Fórmula:C44H62O6S2Forma y color:SolidPeso molecular:751.09HS80
CAS:HS-80, a Fasnall enantiomer, selectively inhibits FASN, blocking lipid synthesis (IC50: 7.13 μM).Fórmula:C19H22N4SPureza:98%Forma y color:SolidPeso molecular:338.47HS79
CAS:HS-79, a Fasnall enantiomer, selectively inhibits FASN with an IC50 of 1.57 μM, blocking tritiated acetate lipid incorporation.Fórmula:C19H22N4SPureza:98%Forma y color:SolidPeso molecular:338.47FASN-IN-4
CAS:FAS-IN-1 is a potent inhibitor of Fatty acid synthase (FAS) wtih IC50 of 10 nM.Fórmula:C26H27N3O4SPureza:98%Forma y color:SolidPeso molecular:477.58FASN-IN-5
CAS:FASN-IN-5 is a FASN inhibitor, useful for studying cancer and metabolic diseases.Fórmula:C29H26N4O2Pureza:99.88%Forma y color:SolidPeso molecular:462.54Malic enzyme inhibitor ME1
CAS:Malic enzyme inhibitor ME1 (ME1) is a specific inhibitor of Malic enzyme (IC50 = 0.15 μM). Malic enzyme inhibitor ME1 reduces cell viability/metabolic activity.Fórmula:C20H21N3O3Pureza:99.91%Forma y color:SolidPeso molecular:351.4Ref: TM-T11940
1mg70,00€1mL*10mM (DMSO)148,00€5mg178,00€10mg326,00€25mg555,00€50mg790,00€100mg1.063,00€500mg2.152,00€CTL-06
CTL-06, a Fatty Acid Synthase (FASN) inhibitor with an IC50 of 3 μM, induces apoptosis, while CTL-12 impedes cell cycle progression in the Sub-G1/S phase andFórmula:C21H21ClN4O4Forma y color:SolidPeso molecular:428.87SREBP/SCAP-IN-2
CAS:SREBP/SCAP-IN-2 (compound 13) acts as a selective inhibitor of SREBP/SCAP [1].Fórmula:C27H37ClF2N4OForma y color:SolidPeso molecular:507.06FASN-IN-1
CAS:FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzymeFórmula:C18H25N3O3S2Pureza:99.92% - >99.99%Forma y color:White SolidPeso molecular:395.541,3-Dipalmitoyl-2-Docosahexaenoyl Glycerol
CAS:1,3-Dipalmitoyl-2-docosahexaenoyl glycerol, a triacylglycerol, features palmitic acid at the sn-1 and sn-3 positions and docosahexaenoic acid at the sn-2 position. Its dietary administration (30 g/kg) has been shown to decrease hepatic triglyceride and cholesterol levels in mice.Fórmula:C57H98O6Forma y color:SolidPeso molecular:879.38FAS-IN-1 Tosylate
FAS-IN-1 Tosylate is an effective fatty acid synthase inhibitor;Has an IC50 of 10 nM.Fórmula:C33H35N3O7S2Pureza:98%Forma y color:SolidPeso molecular:649.78SREBP/SCAP-IN-1
CAS:SREBP/SCAP-IN-1 (compound 10b) serves as a selective inhibitor of SREBP/SCAP [1].Fórmula:C28H40F2N4OForma y color:SolidPeso molecular:486.64ONL-1204
CAS:ONL-1204 is a small molecule, CD95 antigen inhibitor (Fas inhibitor) being developed by ONL Therapeutics for the treatment of retinal detachment.Fórmula:C71H100N18O16Forma y color:SolidPeso molecular:1461.66PFM046
CAS:PFM046 is an antagonist of the liver X receptor (LXR), effectively inhibiting the activation of LXRα and LXRβ, with IC50 values of 2.04 μM and 1.58 μM respectively. It reduces the expression of SCD1 and FASN while increasing ABCA1 expression, and demonstrates antitumor activity in mouse models.Fórmula:C29H42O2Forma y color:SolidPeso molecular:422.643
