Deshidrogenasa
Las deshidrogenasas son enzimas involucradas en las reacciones de oxidación-reducción de las vías metabólicas, desempeñando un papel central en la producción de energía y la respiración celular. Estas enzimas son cruciales para procesos como el ciclo del ácido cítrico, la glucólisis y la oxidación de ácidos grasos. Los inhibidores de deshidrogenasas son herramientas importantes en el estudio de enfermedades metabólicas, cáncer y estrés oxidativo. En CymitQuimica, ofrecemos una selección completa de inhibidores de deshidrogenasas para apoyar su investigación en metabolismo, biología del cáncer y bioquímica.
Se han encontrado 270 productos de "Deshidrogenasa"
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15-PGDH-IN-2
CAS:<p>15-PGDH-IN-2 (Compound 2) is an inhibitor of 15-PGDH with an IC50 value of 0.274 nM. This compound is useful for research into hair loss, bone formation, gastric ulcer healing, and dermal wound healing [1].</p>Fórmula:C16H13NO3S2Forma y color:SolidPeso molecular:331.41GSK321
CAS:<p>GSK321 is an IDH1 inhibitor that prevents cytoplasmic glutamine reductive carboxylation.GSK321 is used in the study of leukemia.</p>Fórmula:C28H28FN5O3Pureza:99.73%Forma y color:SolidPeso molecular:501.55YG1702
CAS:<p>YG1702, a potent inhibitor specific to ALDH18A1, suppresses the proliferation of MYCN-amplified neuroblastoma (NB) and reduces MYCN expression.</p>Fórmula:C23H30N2O7SForma y color:SolidPeso molecular:478.56AZD 4017
CAS:<p>AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).</p>Fórmula:C22H33N3O3SPureza:99.61%Forma y color:SolidPeso molecular:419.58PF-915275
CAS:<p>PF-915275 inhibits 11βHSD1 in humans (Ki=2.3 nM, EC50=15 nM) and affects cortisone-cortisol conversion in hepatocytes.</p>Fórmula:C18H14N4O2SPureza:99.58% - 99.61%Forma y color:SolidPeso molecular:350.3915-PGDH-IN-1
CAS:<p>15-PGDH-IN-1: potent oral 15-PGDH inhibitor, IC50=3nM, useful for tissue repair research.</p>Fórmula:C24H22N4O2Forma y color:SolidPeso molecular:398.46IDH889
CAS:<p>IDH889: Brain-penetrant, mutant-specific IDH1 inhibitor; selective for IDH1 R132* mutations. IC50: 0.02μM (R132H), 0.072μM (R132C), 1.38μM (wild-type).</p>Fórmula:C23H25FN6O2Pureza:≥98%Forma y color:SolidPeso molecular:436.48hDHODH-IN-1
CAS:<p>hDHODH-IN-1 is an inhibitor of human dihydroorotate dehydrogenase (hDHODH) with an anti-inflammatory effect.</p>Fórmula:C17H14N2O2Pureza:99.97%Forma y color:SolidPeso molecular:278.31HSD17B13-IN-2
CAS:<p>HSD17B13-IN-2 (compound 1) serves as a potent inhibitor of hydroxysteroid 17ß-dehydrogenase 13 (HSD17B13) with demonstrable activity in cellular experiments [1</p>Fórmula:C21H23F2NO4Forma y color:SolidPeso molecular:391.41DHODH-IN-22
CAS:<p>DHODH-IN-22: potent, selective DHODH inhibitor, orally active, IC50: 0.3 nM, for AML research.</p>Fórmula:C21H21ClF4N6O5Forma y color:SolidPeso molecular:548.88CHK-336
CAS:<p>CHK-336 (Example 1), an orally active LDHA inhibitor (IC50 <1 nM), suppresses lactate production in mouse hepatocytes and is applicable in hyperoxaluria</p>Fórmula:C24H20F2N4O4S2Forma y color:SolidPeso molecular:530.57Anticancer agent 122
CAS:<p>Anticancer agent 122, a potent inhibitor of human lactate dehydrogenase A (h LDHA), exhibits significant anticancer activities, rendering it suitable for use in</p>Fórmula:C18H15ClN2O2SForma y color:SolidPeso molecular:358.84Tetrahydro-11-dehydrocorticosterone
CAS:<p>Tetrahydro-11-dehydrocorticosterone is an inhibitor of 11β-hydroxysteroid dehydrogenase [1].</p>Fórmula:C21H32O4Forma y color:SolidPeso molecular:348.48α-Pyridoin
CAS:<p>α-Pyridoin (α-pyridoin) is an enediol (enediol) compound that acts as a unique antioxidant.</p>Fórmula:C12H12N2O2Forma y color:SolidPeso molecular:216.24MK-0736
CAS:<p>MK-0736 is a potent and selective 11β-HSD-1 inhibitor.</p>Fórmula:C23H30F3N3O2SForma y color:SolidPeso molecular:469.56DHODH-IN-14
CAS:<p>DHODH-IN-14 is an analog of hydroxyfuran pyrimidine A771726.</p>Fórmula:C15H7F4N3O3Pureza:99.81%Forma y color:SolidPeso molecular:353.23IDH1 Inhibitor 2
CAS:<p>IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).</p>Fórmula:C26H22N4OPureza:98%Forma y color:SolidPeso molecular:406.48BI-3231
CAS:<p>BI-3231 is a hydroxysteroid 17ß-dehydrogenase 13 HSD17B13 inhibitor that inhibits hHSD17B13 .BI-3231 can be used to study cirrhosis.</p>Fórmula:C16H14F2N4O3SPureza:98.2%Forma y color:SolidPeso molecular:380.37CB29
CAS:<p>CB29 is a specific inhibitor of aldehyde dehydrogenase 3A1 (ALDH3A1).</p>Fórmula:C15H15N3O5SPureza:99.36%Forma y color:SolidPeso molecular:349.36ALDH2 modulator 1
CAS:<p>ALDH2 modulator 1 is a potent and orally active modulator of acetaldehyde dehydrogenase-2 (ALDH2), which reduces blood alcohol levels in mice.</p>Fórmula:C18H18ClFN2O3Pureza:99.68%Forma y color:SoildPeso molecular:364.8
