Deshidrogenasa
Las deshidrogenasas son enzimas involucradas en las reacciones de oxidación-reducción de las vías metabólicas, desempeñando un papel central en la producción de energía y la respiración celular. Estas enzimas son cruciales para procesos como el ciclo del ácido cítrico, la glucólisis y la oxidación de ácidos grasos. Los inhibidores de deshidrogenasas son herramientas importantes en el estudio de enfermedades metabólicas, cáncer y estrés oxidativo. En CymitQuimica, ofrecemos una selección completa de inhibidores de deshidrogenasas para apoyar su investigación en metabolismo, biología del cáncer y bioquímica.
Se han encontrado 269 productos de "Deshidrogenasa"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
PDHK-IN-5
<p>PDHK-IN-5, potent PDHK2 (0.006 μM IC50) & PDHK4 (0.0329 μM IC50) inhibitor, may be explored for cancer and diabetes treatment.</p>Fórmula:C30H31N5O2Forma y color:SolidPeso molecular:493.6Etamicastat
CAS:<p>Etamicastat can be used in the research of cardiovascular diseases.</p>Fórmula:C14H15F2N3OSPureza:98%Forma y color:SolidPeso molecular:311.35BI-4916
CAS:<p>BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.</p>Fórmula:C23H24Cl2N2O6SPureza:98.55%Forma y color:SolidPeso molecular:527.42PDHK-IN-3
<p>PDHK-IN-3 (compound 7) is a potent inhibitor of pyruvate dehydrogenase kinase(PDHK) with IC50s of 0.21 and 1.54 μM for PDHK2 and PDHK4, respectively [1].</p>Fórmula:C17H16N2O2Forma y color:SolidPeso molecular:280.32DSM705 hydrochloride
<p>DSM705 hydrochloride: potent antimalarial, pyrrole-based DHODH inhibitor effective against Plasmodium, non-toxic to mammalian DHODH.</p>Fórmula:C19H20ClF3N6OForma y color:SolidPeso molecular:440.857-Hydroxy-4-phenylcoumarin
CAS:<p>7-Hydroxy-4-phenylcoumarin is a dual inhibitor of ALDH-2 and MAO, with IC50 values of 1.5 µM and 0.5 µM, respectively.</p>Fórmula:C15H10O3Forma y color:SolidPeso molecular:238.238BRD7539
CAS:<p>BRD7539B: PfDHODH inhibitor, IC50 0.033μM; selective vs HsDHODH, IC50 >50μM.</p>Fórmula:C23H22FN3O2Pureza:98%Forma y color:SolidPeso molecular:391.44FXR/HSD17B13 modulator 1
CAS:<p>FXR/HSD17B13 modulator 1 (compound 6) is an effective modulator of FXR/HSD17B13, playing a significant role in studies related to metabolic dysfunction-associated steatohepatitis (MASH).</p>Fórmula:C26H19Cl2NO4Forma y color:SolidPeso molecular:480.339RORγt/DHODH-IN-3
<p>RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 has</p>Fórmula:C24H26ClF6N3O3SForma y color:SolidPeso molecular:585.99MDH1/2-IN-1
CAS:<p>MDH1/2-IN-1 is an MDH1/2 inhibitor with IC50 values of 1.07 nM and 1.06 nM, respectively. It suppresses mitochondrial respiration and the HIF-1α pathway. MDH1/2-IN-1 exhibits significant antitumor potential and offers new avenues for developing drugs targeting cancer metabolism.</p>Fórmula:C25H33NO4Forma y color:SolidPeso molecular:411.534LDHA-IN-5
CAS:<p>LDHA-IN-5 is a novel and potent inhibitor targeting both glycolate oxidase (GO) and lactate dehydrogenase A (LDHA), designed for the treatment of primary</p>Fórmula:C27H22FN7O6S3Forma y color:SolidPeso molecular:655.7Indoluidin E
<p>Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.</p>Fórmula:C28H30N4O2Forma y color:SolidPeso molecular:454.56RORγt/DHODH-IN-1
CAS:<p>RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significant</p>Fórmula:C24H26ClF6N3O3SForma y color:SolidPeso molecular:585.99CP-642931
CAS:<p>CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.</p>Fórmula:C17H25N7OPureza:99.67% - >99.99%Forma y color:SolidPeso molecular:343.43Etamicastat hydrochloride
CAS:<p>Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.</p>Fórmula:C14H16ClF2N3OSPureza:98.54%Forma y color:SolidPeso molecular:347.81PS10
CAS:<p>PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of the pyruvate dehydrogenase complex.</p>Fórmula:C14H13NO6SPureza:99.01%Forma y color:SolidPeso molecular:323.32GNE-140 racemate
CAS:<p>GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.</p>Fórmula:C25H23ClN2O3S2Forma y color:SolidPeso molecular:499.04(S)-GNE-140
CAS:<p>(S)-GNE-140 is the less active enantiomer of GNE-140.</p>Fórmula:C25H23ClN2O3S2Forma y color:SolidPeso molecular:499.0511β-HSD1-IN-8
CAS:<p>11β-HSD1-IN-8 is a useful organic compound for research related to life sciences. The catalog number is T65743 and the CAS number is 386704-15-0.</p>Fórmula:C10H8F3NO3Forma y color:SolidPeso molecular:247.173
