Deshidrogenasa
Las deshidrogenasas son enzimas involucradas en las reacciones de oxidación-reducción de las vías metabólicas, desempeñando un papel central en la producción de energía y la respiración celular. Estas enzimas son cruciales para procesos como el ciclo del ácido cítrico, la glucólisis y la oxidación de ácidos grasos. Los inhibidores de deshidrogenasas son herramientas importantes en el estudio de enfermedades metabólicas, cáncer y estrés oxidativo. En CymitQuimica, ofrecemos una selección completa de inhibidores de deshidrogenasas para apoyar su investigación en metabolismo, biología del cáncer y bioquímica.
Se han encontrado 270 productos de "Deshidrogenasa"
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MDH1/2-IN-1
CAS:<p>MDH1/2-IN-1 is an MDH1/2 inhibitor with IC50 values of 1.07 nM and 1.06 nM, respectively. It suppresses mitochondrial respiration and the HIF-1α pathway. MDH1/2-IN-1 exhibits significant antitumor potential and offers new avenues for developing drugs targeting cancer metabolism.</p>Fórmula:C25H33NO4Forma y color:SolidPeso molecular:411.534FXR/HSD17B13 modulator 1
CAS:<p>FXR/HSD17B13 modulator 1 (compound 6) is an effective modulator of FXR/HSD17B13, playing a significant role in studies related to metabolic dysfunction-associated steatohepatitis (MASH).</p>Fórmula:C26H19Cl2NO4Forma y color:SolidPeso molecular:480.339RORγt/DHODH-IN-1
CAS:<p>RORγt/DHODH-IN-1 (compound (R)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.083 μM) and DHODH (IC50: 0.172 μM), which exhibits significant</p>Fórmula:C24H26ClF6N3O3SForma y color:SolidPeso molecular:585.99Indoluidin E
<p>Indoluidin E selectively inhibits DHODH and has an inhibitory effect on cancer cell growth.</p>Fórmula:C28H30N4O2Forma y color:SolidPeso molecular:454.56PDHK-IN-4
<p>PDHK-IN-4 inhibits PDHK2 (IC50: 0.0051 μM) & PDHK4 (IC50: 0.0122 μM), with potential for cancer research.</p>Fórmula:C24H25N5O3Forma y color:SolidPeso molecular:431.49hDHODH-IN-10
<p>hDHODH-IN-10: selective oral inhibitor of hDHODH (IC50: 10.9 nM); blocks cancer cell growth, aids cancer research.</p>Fórmula:C21H15ClF4N2O4Forma y color:SolidPeso molecular:470.8AXKO-0046
<p>AXKO-0046 is an indole derivative and small-molecule LDHB selective inhibitor.</p>Fórmula:C25H33N3Forma y color:SolidPeso molecular:375.5511β-HSD2-IN-2
CAS:<p>11β-HSD2-IN-2 (compound 3) is a selective 17β-HSD2 (17β-hydroxysteroid dehydrogenase type 2) inhibitor with an IC50 of 300 nM, studying osteoporosis.</p>Fórmula:C22H21NO2Pureza:99.61%Forma y color:SolidPeso molecular:331.41GSK864
CAS:<p>GSK864 is an inhibitor of isocitrate dehydrogenase 1 (IDH1) mutant. GSK864 inhibits IDH1 mutants R132C, R132H, and R132G (IC50: 8.8, 15.2, and 16.6 nM).</p>Fórmula:C30H31FN6O4Pureza:97.07%Forma y color:SolidPeso molecular:558.67-Hydroxy-4-phenylcoumarin
CAS:<p>7-Hydroxy-4-phenylcoumarin is a dual inhibitor of ALDH-2 and MAO, with IC50 values of 1.5 µM and 0.5 µM, respectively.</p>Fórmula:C15H10O3Forma y color:SolidPeso molecular:238.238BI-4916
CAS:<p>BI-4916 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor that inhibits SSP and reduces cancer cell migration.</p>Fórmula:C23H24Cl2N2O6SPureza:98.55%Forma y color:SolidPeso molecular:527.42RORγt/DHODH-IN-3
<p>RORγt/DHODH-IN-3 (compound (S)-14d) is a potent, orally active dual inhibitor of RORγt (IC50: 0.098 μM) and DHODH (IC50: 0.432 μM).RORγt/DHODH-IN-1 has</p>Fórmula:C24H26ClF6N3O3SForma y color:SolidPeso molecular:585.99PHGDH-IN-2
<p>PHGDH-IN-2: potent PHGDH inhibitor, IC50=5.2μM; hinders PHGDH cancer cell growth & serine synthesis in MDA-MB-468.</p>Fórmula:C22H20N4O3SForma y color:SolidPeso molecular:420.48T-3764518
CAS:<p>T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).</p>Fórmula:C20H17F6N5O2Pureza:98%Forma y color:SolidPeso molecular:473.37Etamicastat hydrochloride
CAS:<p>Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a peripherally selective dopamine beta-hydroxylase inhibitor that reduces hypertension.</p>Fórmula:C14H16ClF2N3OSPureza:98.54%Forma y color:SolidPeso molecular:347.81CP-642931
CAS:<p>CP-642931 (Sorbitol dehydrogenase-IN-1) is a sorbitol dehydrogenase inhibitor used in the study of diabetes mellitus and cardiovascular disease.</p>Fórmula:C17H25N7OPureza:99.67% - >99.99%Forma y color:SolidPeso molecular:343.43PS10
CAS:PS10 is a broad-spectrum PDK inhibitor that inhibits PDK2 and significantly increases the activity of the pyruvate dehydrogenase complex.Fórmula:C14H13NO6SPureza:99.01%Forma y color:SolidPeso molecular:323.32GNE-140 racemate
CAS:<p>GNE-140 is a potent inhibitor of lactate dehydrogenase A (LDHA). GNE-140 is a racemate mixture of (R)-GNE-140 and (S)-GNE-140.</p>Fórmula:C25H23ClN2O3S2Forma y color:SolidPeso molecular:499.04(S)-GNE-140
CAS:<p>(S)-GNE-140 is the less active enantiomer of GNE-140.</p>Fórmula:C25H23ClN2O3S2Forma y color:SolidPeso molecular:499.0511β-HSD1-IN-8
CAS:<p>11β-HSD1-IN-8 is a useful organic compound for research related to life sciences. The catalog number is T65743 and the CAS number is 386704-15-0.</p>Fórmula:C10H8F3NO3Forma y color:SolidPeso molecular:247.173
