Lipoxigenasa
Las lipoxigenasas son una familia de enzimas que catalizan la oxigenación de ácidos grasos poliinsaturados, llevando a la producción de mediadores lipídicos bioactivos como los leucotrienos y las lipoxinas. Estos mediadores desempeñan roles cruciales en la inflamación, las respuestas inmunitarias y el cáncer. Los inhibidores de la lipoxigenasa se utilizan para estudiar su papel en enfermedades inflamatorias, asma y cáncer. En CymitQuimica, ofrecemos una variedad de inhibidores de lipoxigenasa para apoyar su investigación en inflamación, oncología y metabolismo de los lípidos.
Se han encontrado 124 productos de "Lipoxigenasa"
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Lonapalene
CAS:<p>Lonapalene is a topically effective inhibitor of 5-lipoxygenase.</p>Fórmula:C16H15ClO6Pureza:98.67% - 99.33%Forma y color:SolidPeso molecular:338.74S-2474
CAS:<p>S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities, and inhibits cell death.</p>Fórmula:C20H31NO3SPureza:99.03%Forma y color:SolidPeso molecular:365.535-LOX-IN-1
CAS:<p>5-LOX-IN-1 is a 5-Lipoxygenase (5-LOX) inhibitor (IC50: 2.3 μM).5-LOX-IN-1 can be used for cancer research.</p>Fórmula:C20H18N2O2SPureza:97.45%Forma y color:SolidPeso molecular:350.43h15-LOX-2 inhibitor 1
CAS:<p>Compound 105 (h15-LOX-2 inhibitor 1) is a potent inhibitor of human epithelial 15-lipoxygenase-2 (h15-LOX-2), exhibiting an IC50 of 0.34 μM [1].</p>Fórmula:C17H13F3N2SPureza:98%Forma y color:SolidPeso molecular:334.365,6-dehydro Arachidonic Acid
CAS:<p>5,6-dehydro Arachidonic acid, an arachidonic acid analog with a 5,6 acetylene, inhibits 5-LO; Ki=15 μM in RBL cells, IC50=10 μM in guinea pig leukocytes.</p>Fórmula:C20H30O2Forma y color:SolidPeso molecular:302.45A 78773
CAS:<p>A 78773: potent reversible 5-lipoxygenase inhibitor; active in cells/tissues; targets inflammation, asthma, IBD.</p>Fórmula:C15H13FN2O4Forma y color:SolidPeso molecular:304.27L 670630
CAS:<p>L 670630 is a potent and orally active 5-lipoxygenase inhibitor.</p>Fórmula:C25H26O3Pureza:98%Forma y color:SolidPeso molecular:374.47AA 863
CAS:<p>AA 863 is a 5-lipoxygenase inhibitor, it inhibits the proliferation of human glioma cell lines in dose-dependent.</p>Fórmula:C21H26O5Pureza:98%Forma y color:SolidPeso molecular:358.43A 79175
CAS:<p>A 79175 is a 5-lipoxygenase inhibitor that increases bone formation.</p>Fórmula:C15H13FN2O4Pureza:98%Forma y color:SolidPeso molecular:304.27CMI-392
CAS:<p>CMI-392 is a dual 5-lipoxygenase inhibitor and platelet-activating factor (PAF) receptor antagonist (IC50s: 100 and 10 nM).</p>Fórmula:C31H37ClN2O8SPureza:98%Forma y color:SolidPeso molecular:633.15MLS000545091
CAS:<p>MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.</p>Fórmula:C14H15ClN2OPureza:99.84%Forma y color:SolidPeso molecular:262.73Benoxaprofen
CAS:<p>Benoxaprofen (NSC-299582) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C16H12ClNO3Pureza:98.87%Forma y color:SolidPeso molecular:301.725-Lipoxygenase-In-1
CAS:<p>5-Lipoxygenase-In-1 (compound example 4.10) is a 5-Lipoxygenase inhibitor.</p>Fórmula:C23H28N4O2SForma y color:SolidPeso molecular:424.5617(S)-HpDHA
CAS:<p>17(S)-HpDHA, primarily produced by the 15-Lipoxygenase (LOX) isoenzymes h15-LOX-1 and h15-LOX-2 from docosahexaenoic acid (DHA), is a key regulator in epoxide synthesis through allosteric modulation. Additionally, it effectively inhibits platelet aggregation, demonstrating an EC50 of approximately 1 μM [1].</p>Fórmula:C22H32O4Forma y color:SolidPeso molecular:360.49CCT365623
CAS:<p>CCT365623: oral Lysyl Oxidase inhibitor, potent, selective, good pharmacokinetics, anti-metastatic.</p>Fórmula:C18H17NO4S3Pureza:97.299% - 99.49%Forma y color:SolidPeso molecular:407.53PXS-6302 hydrochloride
CAS:<p>PXS-6302 hydrochloride is a potent irreversible lysine oxidase (LOX) inhibitor, inhibiting Bovine LOX, rh LOXL1, rh LOXL2, rh LOXL3, and rh LOXL4 with IC50 of 3</p>Fórmula:C10H11ClF3NO2SPureza:99.89%Forma y color:SoildPeso molecular:301.71Setileuton
CAS:<p>Setileuton (MK0633) is a specific 5-LOX inhibitor and can be used in research on asthma and atherosclerosis.</p>Fórmula:C22H17F4N3O4Pureza:98.85% - 99.35%Forma y color:SolidPeso molecular:463.38h15-LOX-2 inhibitor 3
CAS:<p>Compound 13, identified as h15-LOX-2 inhibitor 3, exhibits inhibitory activity against h15-LOX, with IC50 and Ki values of 25 μM and 15.1 μM, respectively.</p>Fórmula:C22H13N5O3Forma y color:SolidPeso molecular:395.37AZD 4407
CAS:<p>AZD 4407 is a potent inhibitor of 5-lipoxygenase.</p>Fórmula:C19H21NO3S2Pureza:98%Forma y color:SolidPeso molecular:375.5ALOX15-IN-1
<p>ALOX15-IN-1 (8b) inhibits rabbit/human ALOX15; IC50: 0.04 μM for LA, 2.06 μM for AA.</p>Fórmula:C24H31N3O5SForma y color:SolidPeso molecular:473.59
