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Lipoxigenasa

Lipoxigenasa

Las lipoxigenasas son una familia de enzimas que catalizan la oxigenación de ácidos grasos poliinsaturados, llevando a la producción de mediadores lipídicos bioactivos como los leucotrienos y las lipoxinas. Estos mediadores desempeñan roles cruciales en la inflamación, las respuestas inmunitarias y el cáncer. Los inhibidores de la lipoxigenasa se utilizan para estudiar su papel en enfermedades inflamatorias, asma y cáncer. En CymitQuimica, ofrecemos una variedad de inhibidores de lipoxigenasa para apoyar su investigación en inflamación, oncología y metabolismo de los lípidos.

Se han encontrado 124 productos de "Lipoxigenasa"

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  • YS-121

    CAS:
    <p>YS121 inhibits mPGES-1 (IC50=3.4μM) &amp; 5-LOX (IC50=6.5μM), and lowers PGE2 in A549 cells (EC50=12μM).</p>
    Fórmula:C20H26ClN3O2S
    Forma y color:Solid
    Peso molecular:407.96
  • LP117

    CAS:
    <p>LP117 is a novel and effective inhibitor of 5-Lipoxygenase (5-LO) product synthesis (IC50: 1.1 μM).</p>
    Fórmula:C21H23ClN4O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:430.95
  • Fenleuton

    CAS:
    <p>Fenleuton is a 5-lipoxygenase inhibitor.</p>
    Fórmula:C17H15FN2O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:314.31
  • L 656224

    CAS:
    L 656224 is a 5-LO inhibitor.
    Fórmula:C20H21ClO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:344.83
  • RG 6866

    CAS:
    RG 6866 is a inhibitor of 5-lipoxygenase.
    Fórmula:C16H17NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:271.31
  • EP6

    CAS:
    <p>EP6 blocks 5-LO, key in the AA cascade, reducing leukotrienes to curb inflammation and allergies.</p>
    Fórmula:C24H30N4O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:390.52
  • HZ52

    CAS:
    <p>HZ52: Potent reversible 5-LO inhibitor; IC50 0.7 μM; blocks LTs in human leukocytes.</p>
    Fórmula:C24H26ClN3O2S
    Forma y color:Solid
    Peso molecular:456
  • Cgp 8065

    CAS:
    <p>Cgp 8065 is a filaricidal compound, a dithiocarbamate-derivative of amoscanate.</p>
    Fórmula:C16H15N3O4S2
    Forma y color:Solid
    Peso molecular:377.44
  • ICI 211965

    CAS:
    <p>ICI 211965 is a selective and orally potent of 5-Lipoxygenase (5-LPO).</p>
    Fórmula:C24H23NO2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:389.51
  • Lipoxygenin

    CAS:
    <p>Lipoxygenin: IC50 of 5 μM inhibits 5-LO, hedgehog, TGF-β, activin A, BMP, Wnt signaling, and boosts cardiac marker TnnT in iPSCs.</p>
    Fórmula:C24H22N2O4
    Forma y color:Solid
    Peso molecular:402.44
  • LY 269415

    CAS:
    <p>LY 269415 is an anti-inflammatory agent with antioxidant properties in vitro and could be beneficial as therapeutic agents in inflammatory arthritis.</p>
    Fórmula:C19H28N2O2S
    Forma y color:Solid
    Peso molecular:348.5
  • Fluindione

    CAS:
    <p>Fluindione is a hematologic drug.</p>
    Fórmula:C15H9FO2
    Forma y color:Solid
    Peso molecular:240.23
  • AHR-5333

    CAS:
    <p>AHR-5333 an antiallergy agent.</p>
    Fórmula:C30H33F2NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:509.58
  • BI-L 357

    CAS:
    <p>BI-L 357, a prodrug of BL-L 226, is a selective, orally active inhibitor of 5-lipoxygenase.</p>
    Fórmula:C18H18O4S
    Forma y color:Solid
    Peso molecular:330.4
  • LY 221068

    CAS:
    <p>LY 221068 is a potent antioxidant with anti-inflammatory activity.</p>
    Fórmula:C20H30N2O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:362.53
  • PF-4191834

    CAS:
    PF-4191834: Non-iron, non-redox 5-LOX inhibitor, IC50 = 229 nM, 300x selective over 12/15-LOX, inactive on COX enzymes.
    Fórmula:C22H23N3O2S
    Pureza:99.83% - 99.98%
    Forma y color:Solid
    Peso molecular:393.5
  • 2-TEDC

    CAS:
    <p>2-TEDC: Potent LOX inhibitor, blocks 5-LOX, 12-LOX, 15-LOX (IC50: 0.09, 0.013, 0.5 μM); aids atherosclerosis research.</p>
    Fórmula:C16H13NO4S
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:315.34
  • Butibufen

    CAS:
    Butibufen (FF-106) is a non-steroidal anti-inflammatory compound and LOX inhibitor with analgesic and antipyretic activity for the study of rheumatic diseases.
    Fórmula:C14H20O2
    Pureza:98.11% - 98.91%
    Forma y color:Solid
    Peso molecular:220.31
  • S-2474

    CAS:
    <p>S-2474, an inhibitor of COX-2 and 5-lipoxygenase, has anti-inflammatory and neuroprotective activities, and inhibits cell death.</p>
    Fórmula:C20H31NO3S
    Pureza:99.03%
    Forma y color:Solid
    Peso molecular:365.53
  • Utreloxastat

    CAS:
    <p>Utreloxastat (PTC857) is a novel 15-lipoxygenase inhibitor that can be used to study amyotrophic lateral sclerosis<br>.</p>
    Fórmula:C18H28O2
    Pureza:99.95%
    Forma y color:Solid
    Peso molecular:276.41