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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5398 productos de "Neurociencia"

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  • SNRI-IN-1
    Targetmol
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    SNRI-IN-1

    CAS:
    <p>SNRI-IN-1 (Compound 7a) acts as a dual inhibitor of serotonin and noradrenaline monoamine reuptake, with a P-glycoprotein Efflux Ratio of 20 [1].</p>
    Fórmula:C16H20Cl2N2O2
    Forma y color:Solid
    Peso molecular:343.25

    Ref: TM-T87412

  • ChEs/MAOs-IN-2
    Targetmol
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    ChEs/MAOs-IN-2

    CAS:
    <p>ChEs/MAOs-IN-2 (compound a11) serves as an inhibitor for both cholinesterases and monoamine oxidases, exhibiting IC 50 values of 0.10 µM for MAO-A, 0.20 µM for MAO-B, 0.30 µM for AChE, and 0.40 µM for BChE. This compound shows promise for Alzheimer's disease research [1].</p>
    Fórmula:C15H12N2O3S
    Forma y color:Solid
    Peso molecular:300.33

    Ref: TM-T86047

  • Logo de CymitQuimica
    Targetmol
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    5-HT1A antagonist 1

    <p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>
    Fórmula:C23H29ClN6O2
    Forma y color:Solid
    Peso molecular:456.97

    Ref: TM-T62843

  • PTCA
    Targetmol
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    PTCA

    CAS:
    <p>PTCA is a potent ligand for Ca2+/calmodulin-dependent protein kinase II α (CaMKIIα), with a pKi value of 7.2.</p>
    Fórmula:C10H5Cl2NO2S
    Forma y color:Solid
    Peso molecular:274.123

    Ref: TM-T204835

  • R-96544 hydrochloride
    Targetmol
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    R-96544 hydrochloride

    CAS:
    <p>5-HT2 receptor antagonist</p>
    Fórmula:C22H29NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:355.47

    Ref: TM-T23219

  • HW161023
    Targetmol
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    HW161023

    CAS:
    <p>HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.</p>
    Fórmula:C20H24F2N4O
    Forma y color:Solid
    Peso molecular:374.428

    Ref: TM-T206896

  • Alixorexton
    Targetmol
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    Alixorexton

    CAS:
    <p>Alixorexton is an agonist of the orexin-2 receptor (orexin-2 receptor) and is utilized in obesity research.</p>
    Fórmula:C21H30N2O5S
    Forma y color:Solid
    Peso molecular:422.538

    Ref: TM-T205053

  • AChE-IN-84
    Targetmol
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    AChE-IN-84

    CAS:
    <p>AChE-IN-84 (compound 21) is an inhibitor of AChE.</p>
    Fórmula:C6H15Br2N
    Forma y color:Solid
    Peso molecular:260.998

    Ref: TM-T205413

  • 5-IAI hydrochloride
    Targetmol
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    5-IAI hydrochloride

    CAS:
    <p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>
    Fórmula:C9H11ClIN
    Forma y color:Solid
    Peso molecular:295.548

    Ref: TM-T204949

  • Moxetomidate
    Targetmol
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    Moxetomidate

    CAS:
    <p>Moxetomidate is a GABAA receptor (GABAA receptor) agonist with hypnotic properties.</p>
    Fórmula:C15H18N2O3
    Forma y color:Solid
    Peso molecular:274.315

    Ref: TM-T205308

  • BGT1-IN-1
    Targetmol
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    BGT1-IN-1

    CAS:
    <p>BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.</p>
    Fórmula:C6H9NO2
    Forma y color:Solid
    Peso molecular:127.14

    Ref: TM-T200935

  • Nedemelteon
    Targetmol
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    Nedemelteon

    CAS:
    <p>Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).</p>
    Fórmula:C15H18N2O2
    Forma y color:Solid
    Peso molecular:258.32

    Ref: TM-T201036

  • Remlifanserin
    Targetmol
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    Remlifanserin

    CAS:
    <p>Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).</p>
    Fórmula:C24H29F2N3O2
    Forma y color:Solid
    Peso molecular:429.50

    Ref: TM-T201055

  • Relicpixant
    Targetmol
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    Relicpixant

    CAS:
    <p>Relicpixant is a potent purine receptor (P2X) antagonist.</p>
    Fórmula:C20H19ClF2N4O5S
    Forma y color:Solid
    Peso molecular:500.9

    Ref: TM-T200883

  • Rodatristat ethyl
    Targetmol
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    Rodatristat ethyl

    CAS:
    <p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels &amp; lowering PAH at low doses.</p>
    Fórmula:C29H31ClF3N5O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:590.04

    Ref: TM-T16779

  • PXS-4787 hydrochloride
    Targetmol
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    PXS-4787 hydrochloride

    CAS:
    <p>PXS-4787 hydrochloride is a specific and potent pan-lysyl oxidase inhibitor that effectively eliminates the activity of lysyl oxidase. It exhibits varying IC50 values against different forms of the enzyme, including 2 μM (Bovine LOX), 3.2 μM (rh LOXL1), 0.6 μM (rh LOXL2), 1.4 μM (rh LOXL3), and 0.2 μM (rh LOXL4). In addition, PXS-4787 hydrochloride reduces the deposition and cross-linking of collagen I secreted by human fibroblasts.</p>
    Fórmula:C10H13ClFNO2S
    Forma y color:Solid
    Peso molecular:265.73

    Ref: TM-T201314

  • BACE1-IN-5
    Targetmol
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    BACE1-IN-5

    CAS:
    <p>BACE1-IN-5 inhibits BACE1 (IC50: 9.1 nM) &amp; Aβ production (IC50: 0.82 nM), enhances hERG inhibition &amp; P-gp efflux.</p>
    Fórmula:C18H16F5N5O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:461.41

    Ref: TM-T10453

  • Logo de CymitQuimica
    Targetmol
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    LP 12 hydrochloride hydrate

    <p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>
    Fórmula:C32H39N3O·HCl·xH2O
    Forma y color:Solid

    Ref: TM-T64269

  • MAO-B-IN-42
    Targetmol
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    MAO-B-IN-42

    CAS:
    <p>MAO-B-IN-42 (Compound 4f) is a selective and reversible monoamine oxidase-B (MAO-B) inhibitor, with an IC50 value of 0.184 μM. By blocking the oxidative deamination of monoamines catalyzed by MAO-B, it helps maintain neurotransmitter levels. MAO-B-IN-42 shows potential for research into Parkinson's disease.</p>
    Fórmula:C19H12FNO2
    Forma y color:Solid
    Peso molecular:305.302

    Ref: TM-T206712

  • ASP-2205
    Targetmol
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    ASP-2205

    CAS:
    <p>ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.</p>
    Fórmula:C19H28N2O
    Forma y color:Solid
    Peso molecular:300.44

    Ref: TM-T201450