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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5400 productos de "Neurociencia"

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  • Logo de CymitQuimica
    Targetmol
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    AChE-IN-8

    <p>AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.</p>
    Fórmula:C20H22N4O2S
    Forma y color:Solid
    Peso molecular:382.48

    Ref: TM-T61648

  • Cyproflanilide
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    Cyproflanilide

    CAS:
    <p>Cyproflanilide is a GABAR antagonist that exhibits high activity against a variety of pests, including those from the Lepidoptera, Coleoptera, and Thysanoptera orders.</p>
    Fórmula:C28H17BrF12N2O2
    Forma y color:Solid
    Peso molecular:721.33

    Ref: TM-T201028

  • Nedemelteon
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    Nedemelteon

    CAS:
    <p>Nedemelteon is an agonist of the melatonin receptor (melatonin receptor).</p>
    Fórmula:C15H18N2O2
    Forma y color:Solid
    Peso molecular:258.32

    Ref: TM-T201036

  • BGT1-IN-1
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    BGT1-IN-1

    CAS:
    <p>BGT1-IN-1 (compound 9) is an effective inhibitor of BGT1, demonstrating IC50 values of 13.9 µM for hBGT1 and 58.3 µM for GAT3. It exhibits no cytotoxic effects and possesses neuroprotective activity.</p>
    Fórmula:C6H9NO2
    Forma y color:Solid
    Peso molecular:127.14

    Ref: TM-T200935

  • DL-Thyroxine
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    DL-Thyroxine

    CAS:
    <p>DL-Thyroxine is a thyroid hormone that acts as a monoamine oxidase (monoamine oxidase) inhibitor.</p>
    Fórmula:C15H11I4NO4
    Forma y color:Solid
    Peso molecular:776.87

    Ref: TM-T204436

  • LY3020371 hydrochloride
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    LY3020371 hydrochloride

    CAS:
    <p>LY3020371 HCl: potent mGlu2/3 antagonist, antidepressant-like; Ki: 5.3/2.5 nM, IC50: 16.2 nM for cAMP inhibition.</p>
    Fórmula:C15H16ClF2NO5S
    Forma y color:Solid
    Peso molecular:395.81

    Ref: TM-T11911

  • Desmethylflunitrazepam
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    Desmethylflunitrazepam

    CAS:
    <p>Desmethylflunitrazepam (Norflunitrazepam) is a benzodiazepine derivative and an active metabolite of Flunitrazepam.</p>
    Fórmula:C15H10FN3O3
    Forma y color:Solid
    Peso molecular:299.26

    Ref: TM-T201723

  • SZ1676
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    SZ1676

    CAS:
    <p>SZ1676 is a derivative of SZ1677, which is an agent of neuromuscular blocking.</p>
    Fórmula:C37H59BrN2O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:707.78

    Ref: TM-T13908

  • Logo de CymitQuimica
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    CaMKK2-IN-1

    CAS:
    <p>CaMKK2-IN-1 is a selective and potent inhibitor of CaMKK2, exhibiting an IC50 of 7 nM.</p>
    Fórmula:C22H22N2O3
    Peso molecular:362.42

    Ref: TM-T208827

  • Logo de CymitQuimica
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    AChE-IN-47

    CAS:
    <p>AChE-IN-47 (compound g17) is an acetylcholinesterase (AChE) inhibitor with an IC50 of 0.24 μM. It prevents the self-aggregation of β-amyloid peptides and exhibits neuroprotective properties by effectively reducing the accumulation of intracellular reactive oxygen species (ROS).</p>
    Fórmula:C20H17F3N4O4S
    Peso molecular:466.43

    Ref: TM-T208738

  • Tipindole
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    Tipindole

    CAS:
    <p>Tipindole is a serotonin antagonist utilized in research related to depression.</p>
    Fórmula:C16H20N2O2S
    Forma y color:Solid
    Peso molecular:304.41

    Ref: TM-T201819

  • DL-AP5 lithium
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    DL-AP5 lithium

    CAS:
    <p>DL-AP5 (2-APV) lithium is a competitive antagonist of the NMDA (N-Methyl-D-aspartate) receptor. It exhibits notable analgesic activity and specifically blocks channels in the rabbit retina.</p>
    Fórmula:C5H11LiNO5P
    Forma y color:Solid
    Peso molecular:203.06

    Ref: TM-T201724

  • Logo de CymitQuimica
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    GABAA receptor agonist 1

    <p>Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.</p>
    Fórmula:C20H30O3
    Forma y color:Solid
    Peso molecular:318.45

    Ref: TM-T60842

  • Amyloid-β-IN-2
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    Amyloid-β-IN-2

    CAS:
    <p>Amyloid-β-IN-2 (Compound EX.112) is a selective inhibitor of γ-secretase. In H4 cells, it demonstrates inhibitory activity on Aβ42 secretion, with an EC50 value of 226 nM. Amyloid-β-IN-2 holds potential for research in Alzheimer's disease (AD) and diseases associated with Aβ deposition.</p>
    Fórmula:C22H21F2N3O2
    Forma y color:Solid
    Peso molecular:397.42

    Ref: TM-T207418

  • 2002-G12
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    2002-G12

    CAS:
    <p>2002-G12 (compound 5a) is an Aβ42 inhibitor that can reduce Aβ42 toxicity by 76%. It is applicable in Alzheimer's research.</p>
    Fórmula:C20H16N6
    Forma y color:Solid
    Peso molecular:340.381

    Ref: TM-T204830

  • γ-secretase modulator 6
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    γ-secretase modulator 6

    CAS:
    <p>Gamma-secretase modulator 6 (Example 50) is a gamma-secretase modulator. It inhibits Aβ42 secretion in HEK cell lines stably expressing APP (Aβ amyloid precursor protein) with a pIC50 of 8.1. This compound is applicable in Alzheimer's disease research.</p>
    Fórmula:C25H26N6O2
    Forma y color:Solid
    Peso molecular:442.513

    Ref: TM-T206107

  • Logo de CymitQuimica
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    AAK1-IN-3 TFA

    <p>AAK1-IN-3 TFA, an AAK1 inhibitor with IC50 of 11 nM, crosses the blood-brain barrier, is a quinoline analogue, and may aid neuropathic pain research.</p>
    Fórmula:C24H22F6N4O4
    Forma y color:Solid
    Peso molecular:544.45

    Ref: TM-T63834

  • AChE/Aβ-IN-5
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    AChE/Aβ-IN-5

    CAS:
    <p>Compound AV-2, also known as AChE/Aβ-IN-5, is a bifunctional inhibitor that acts on AChE and auto-induced Aβ (Amyloid-β) aggregation. This compound has demonstrated significant efficacy in mitigating cognitive impairment in mice induced by scopolamine and Aβ [1].</p>
    Fórmula:C25H24N4
    Forma y color:Solid
    Peso molecular:380.48

    Ref: TM-T85551

  • AChE-IN-63
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    AChE-IN-63

    CAS:
    <p>AChE-IN-63 (Compound 5AD) serves as a selective inhibitor of hAChE, exhibiting an IC 50 value of 0.103 μM. Moreover, it inhibits hBChE and hBACE-1 with IC 50 values of 10 μM and 1.342 μM, respectively. AChE-IN-63 is effective in inhibiting Aβ aggregation and preventing the formation and deposition of Aβ1-42. It can effectively penetrate the blood-brain barrier and is orally bioavailable. This compound is primarily utilized in research related to Alzheimer's disease [1].</p>
    Fórmula:C18H19N5O
    Forma y color:Solid
    Peso molecular:321.38

    Ref: TM-T85555

  • NB-360
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    NB-360

    CAS:
    <p>NB-360: potent, brain-penetrant BACE1/2 inhibitor; IC50s: 5-6 nM; high selectivity vs pepsin, cathepsin E/D.</p>
    Fórmula:C21H19F4N5O2
    Pureza:99.72%
    Forma y color:Solid
    Peso molecular:449.4

    Ref: TM-T12188