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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

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  • TMPH

    CAS:
    <p>TMPH is an inhibitor of nAChR and inhibits nAChRs lacking α5, α6, or β3 subunits. TMPH can be used in studies about nAChR dysfunction or neurological disorders.</p>
    Fórmula:C16H31NO2
    Pureza:99.78%
    Forma y color:Soild
    Peso molecular:269.42
  • Neuronal Signaling Compound Library


    <p>A unique collection of xnum compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;</p>
    Forma y color:Odour Solid
  • ACG548B

    CAS:
    <p>ACG548B inhibits AChE/BChE with IC50s of 1.78/0.496 μM; favors AChE over BChE/ChoK.</p>
    Fórmula:C38H34Br2Cl2N4
    Forma y color:Solid
    Peso molecular:777.43
  • β-Amyloid (10-20)

    CAS:
    <p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>
    Fórmula:C71H99N17O16
    Pureza:98%
    Forma y color:Lyophilized Powder
    Peso molecular:1446.65
  • R 50595

    CAS:
    <p>R 50595 is a selective non-competitive cisapride antagonist.</p>
    Fórmula:C30H35Cl2F2N3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:594.52
  • Otaplimastat HCl

    CAS:
    <p>Otaplimastat HCl is an MMP inhibitor reducing NMDA-mediated excitotoxicity and oxidative stress, restoring TIMP levels, and protecting vascular permeability.</p>
    Fórmula:C28H35ClN6O5
    Pureza:100%
    Peso molecular:571.07
  • XL01126


    <p>XL01126 degrades LRRK2 (DC50: 14 nM G2019S, 32 nM WT), crosses the blood-brain barrier, aiding Parkinson's studies.</p>
    Fórmula:C50H64ClFN10O6S2
    Forma y color:Solid
    Peso molecular:1019.69
  • NNC 11-1607

    CAS:
    <p>NNC 11-1607 is a functionally selective agonist of M(1)/M(4) mAChR.</p>
    Fórmula:C30H32N6O2S2
    Forma y color:Solid
    Peso molecular:572.74
  • Aceclidine (hydrochloride)

    CAS:
    <p>agonist of muscarinic receptors</p>
    Fórmula:C9H16ClNO2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:205.68
  • Sodium Channel Targeted Library


    <p>A unique collection of xnum sodium channel blockers and agonists for high throughput and high content screening;</p>
    Forma y color:Odour Solid
  • Coumarinic acid

    CAS:
    <p>Coumarinic acid serves as a brain-penetrating inhibitor of AChE (acetylcholinesterase) and β-amyloid, with applications in anti-Alzheimer's drug research [1].</p>
    Fórmula:C9H8O3
    Forma y color:Solid
    Peso molecular:164.16
  • Maesopsin


    <p>Maesopsin is a useful organic compound for research related to life sciences and the catalog number is T124581.</p>
    Fórmula:C15H12O6
    Forma y color:Solid
    Peso molecular:288.255
  • Aminoacetone hydrochloride

    CAS:
    <p>Aminoacetone hydrochloride (1-Aminoacetone Hydrochloride) is an oxidative agent that induces loss of ferritin ferrireductase activity and iron uptake.</p>
    Fórmula:C3H8ClNO
    Pureza:99.76%
    Forma y color:Solid
    Peso molecular:109.56
  • Amyloid β-Protein (1-24)

    CAS:
    <p>Amyloid β-Protein (1-24) is a peptide identified through peptide screening. This tool predominantly employs immunoassays to gather and analyze active peptides. Peptide screening is utilized in studies involving protein interactions, functional analysis, and epitope screening, particularly relevant in the research and development of active molecules.</p>
    Fórmula:C130H183N35O40
    Peso molecular:2876.05
  • PSEN1-IN-2


    <p>PSEN1-IN-2 (Compound 13K) is a potent inhibitor of both PSEN1-APH1A and PSEN1-APH1B complexes, exhibiting IC50 values of 6.9 nM and 2.4 nM, respectively.</p>
    Fórmula:C20H18ClFN2O3S
    Forma y color:Solid
    Peso molecular:420.88
  • 5-Hydroxymethyl tolterodine formate

    CAS:
    <p>5-Hydroxymethyl tolterodine (formate) (PNU-200577 (formic)) is an active metabolite of the muscarinic acetylcholine receptor antagonists Tolterodine and Fesoterodine. It is synthesized by the cytochrome P450 (CYP) isoenzyme CYP2D6 and plasma esterases.</p>
    Fórmula:C23H33NO4
    Forma y color:Solid
    Peso molecular:387.51
  • Biphenyl-3′,3,4,4′-tetrol

    CAS:
    <p>Biphenyl-3′,3,4,4′-tetrol (BPT) is a potent inhibitor of Aβ40 aggregation and can be utilized in research related to neurodegenerative diseases such as Alzheimer's.</p>
    Fórmula:C12H10O4
    Forma y color:Solid
    Peso molecular:218.21
  • Bis-(-)-8-demethylmaritidine


    <p>Bis-(-)-8-demethylmaritidine, a natural alkaloid, serves as a potent inhibitor of acetylcholinesterase (AChE) and is utilized in Alzheimer's disease research [1</p>
    Forma y color:Odour Solid
  • β-Amyloid (35-25)

    CAS:
    <p>β-Amyloid (35-25) is the reverse sequence of β-Amyloid (25-35).</p>
    Fórmula:C45H81N13O14S
    Peso molecular:1060.27
  • Orexin A (human, rat, mouse) (TFA)


    <p>Endogenous orexin receptor agonist with Ki of 20 nM (OX1) and 38 nM (OX2), promotes feeding, may regulate sleep-wake cycle.</p>
    Fórmula:C154H244N47F3O46S4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3675.12
  • β-Amyloid (10-35), amide

    CAS:
    <p>β-Amyloid (10-35), amide, is a chemical compound consisting of 26 amino acids, specifically residues 10-35 of the Aβ peptide.</p>
    Fórmula:C133H205N35O36S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2902.33
  • (+)-OSU 6162

    CAS:
    <p>(+)-OSU 6162 (Piperidine, 3-[3-(methylsulfonyl)phenyl]-1-propyl-, (3R)-) is an agonist of 5-HT Receptor with anti-Alzheimer and antidepressant activities.</p>
    Fórmula:C15H23NO2S
    Pureza:98.19%
    Forma y color:Soild
    Peso molecular:281.41
  • BChE-IN-16


    <p>BChE-IN-16 (compound 87) is a potent inhibitor of human butyrylcholinesterase (hBChE) exhibiting an inhibition concentration half-maximum (IC50) of 3.8 nM.</p>
    Fórmula:C28H32FNO2
    Forma y color:Solid
    Peso molecular:433.56
  • β-Amyloid (11-22)

    CAS:
    <p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>
    Fórmula:C70H102N18O18
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1483.67
  • Hamaline

    CAS:
    <p>Hamaline (9-(4-chlorobenzyl)-6-methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole) is a substrate-selective cyclooxygenase-2 (COX-2) inhibitor.</p>
    Fórmula:C20H19ClN2O
    Pureza:99.88%
    Forma y color:Soild
    Peso molecular:338.83
  • MGS0274

    CAS:
    <p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>
    Fórmula:C21H32FNO7
    Forma y color:Solid
    Peso molecular:429.485
  • CALP2

    CAS:
    <p>CALP2 is a CaM antagonist blocking EF-hand/Ca2+ site; inhibits CaM phosphodiesterase, raises Ca2+, and activates alveolar macrophages.</p>
    Fórmula:C68H104N14O13S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1357.72
  • β-Secretase Inhibitor II

    CAS:
    <p>β-Secretase Inhibitor II is a tripeptide aldehyde compound that acts as an inhibitor of β-Secretase.</p>
    Fórmula:C25H39N3O5
    Forma y color:Solid
    Peso molecular:461.59
  • β-Amyloid (1-40)

    CAS:
    <p>Amyloid β1-40 is one of the fragments generated after cleavage of the amyloid peptide precursor protein by β and γ secretases.</p>
    Fórmula:C194H295N53O58S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:4329.82
  • L-AP3

    CAS:
    <p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>
    Fórmula:C3H8NO5P
    Forma y color:White Hygroscopic Solid
    Peso molecular:169.073
  • AChE-IN-60


    <p>AChE-IN-60 (compound 6k) is a potent inhibitor of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), with IC50 values of 27 nM and 43 nM, respectively. It also inhibits monoamine oxidase MAO-A and MAO-B, with IC50 values of 353 nM and 716 nM, respectively.</p>
    Fórmula:C24H29N3O4S3
    Peso molecular:519.13202
  • AChE-IN-45


    <p>AChE-IN-45 (Compound 14) is an acetylcholinesterase (AChE) inhibitor exhibiting an IC50 value of 11.57±0.45 nM, and it demonstrates both antioxidant and</p>
    Forma y color:Odour Solid
  • rac-Desethyl Oxybutynin (hydrochloride)

    CAS:
    <p>rac-Desethyl oxybutynin, active oxybutynin metabolite, binds to mAChRs; K_i values 3.12-16 nM; lowers rat micturition pressure.</p>
    Fórmula:C20H28ClNO3
    Forma y color:Solid
    Peso molecular:365.89
  • VVZ-149


    <p>VVZ-149 is an antagonist of both serotonin receptor 2A (5HT2A) and glycine transporter type 2 (GlyT2), with potential anti-nociceptive activity.</p>
    Forma y color:Solid
  • Tariquidar methanesulfonate hydrate

    CAS:
    <p>m-PEG8-Ms is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC compounds.</p>
    Fórmula:C40H58N4O18S2
    Pureza:98.13%
    Forma y color:Solid
    Peso molecular:947.04
  • Rapastinel acetate

    CAS:
    <p>Rapastinel acetate is a modulator of N-methyl-D-aspartate (NMDA) receptor and a partial agonist of glycine site long-lasting antidepressant effects.</p>
    Fórmula:C20H35N5O8
    Pureza:99.6%
    Forma y color:Soild
    Peso molecular:473.52
  • Amyloid β Peptide (42-1)(human) acetate


    <p>Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42).</p>
    Pureza:95.20%
    Forma y color:Soild
  • 5H-Pyrido[4,3-b]indole

    CAS:
    <p>5H-Pyrido[4,3-b]indole is a potential AchE/ChE inhibitor with potential antiviral activity for the study of neurodegenerative diseases.</p>
    Fórmula:C11H8N2
    Pureza:99.6%
    Forma y color:Solid
    Peso molecular:168.2
  • GluN2B receptor modulator-1

    CAS:
    <p>GluN2B receptor modulator-1 is a selective negative allosteric modulator of NMDA receptor GluN2B subunits (IC50 31 nM), valuable for neuropharmacology studies.</p>
    Fórmula:C17H15F3N4O2S
    Pureza:99.56%
    Forma y color:Solid
    Peso molecular:396.39
  • Davunetide acetate


    <p>Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS.</p>
    Fórmula:C38H64N10O14
    Pureza:99.52% - 99.78%
    Forma y color:Solid
    Peso molecular:884.97
  • Echimidine N-oxide

    CAS:
    <p>Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.</p>
    Fórmula:C20H31NO8
    Forma y color:Solid
    Peso molecular:413.467
  • nAChR agonist 2

    CAS:
    <p>Compound 8, identified as a selective alpha4beta2 (α4β2) neuronal acetylcholine receptor (nAChR) agonist, demonstrates a dissociation constant (Kd) of 26 nM,</p>
    Fórmula:C11H16N2
    Forma y color:Solid
    Peso molecular:176.263
  • JH-XII-03-02

    CAS:
    <p>JH-XII-03-02 is a potent and selective leucine-rich repeat kinase 2 (LRRK2) proteolysis targeting chimera (PROTAC) degrader, utilized in Parkinson's Disease (PD</p>
    Fórmula:C43H51N9O10
    Pureza:98%
    Forma y color:Solid
    Peso molecular:853.92
  • Calmodulin Binding Peptide 1

    CAS:
    <p>Calmodulin Binding Peptide 1, a high-affinity MLCK-derived inhibitor, blocks IP3-induced Ca2+ release.</p>
    Fórmula:C231H373N69O70S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:5301.1
  • Calcium Channel Compound Library


    <p>A unique collection of 140 calcium channel blockers and agonists for high throughput and high content screening;</p>
    Forma y color:Odour Solid
  • TIP 39, Tuberoinfundibular Neuropeptide

    CAS:
    <p>TIP39 is a synthetic neuropeptide agonist for human and rat PTH2 receptors from the hypothalamus.</p>
    Fórmula:C202H325N61O54S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:4504.2
  • Tiquizium

    CAS:
    <p>Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease.</p>
    Fórmula:C19H24NS2
    Pureza:99.82%
    Forma y color:Solid
    Peso molecular:330.53
  • Calmodulin-Dependent Protein Kinase II (281-309)

    CAS:
    <p>Calmodulin-Dependent Protein Kinase II (281-309) is a synthetic peptide that can be phosphorylated at Thr286 by PKC and inhibits CaM kinase II (IC50 = 80 nM).</p>
    Fórmula:C146H254N46O39S3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3374.06
  • TC-2559 difumarate

    CAS:
    <p>TC-2559 difumarate: Oral α4β2 nAChR partial agonist, CNS-selective, EC50 0.18 μM, prefers α4β2 over α2β4/α4β4/α3β4, antinociceptive.</p>
    Fórmula:C20H26N2O9
    Forma y color:Solid
    Peso molecular:438.43
  • OXA(17-33)

    CAS:
    <p>Potent and selective peptide orexin OX1 receptor agonist (EC50 values are 8.29 and 187 nM for OX1 and OX2 receptors respectively). Truncated form of orexin A.</p>
    Fórmula:C79H125N23O22
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1749
  • SC-53116

    CAS:
    <p>SC-53116 HCl can increase the production of serotonin in central nervous system tissues and is a psychoactive agent.</p>
    Fórmula:C16H22ClN3O2
    Forma y color:Solid
    Peso molecular:323.82
  • AChE/BChE-IN-11

    CAS:
    <p>AChE/BChE-IN-11, natural from artichoke leaves, inhibits AChE and BChE (IC50: 70/71 μM) for Alzheimer's research.</p>
    Fórmula:C21H22O12
    Forma y color:Solid
    Peso molecular:466.39
  • β-Secretase Inhibitor I

    CAS:
    <p>β-Secretase Inhibitor I is a highly potent inhibitor of the β-secretase enzyme.</p>
    Fórmula:C18H18F3N5O2S
    Forma y color:Solid
    Peso molecular:425.43
  • N-Ethyl-N-(3-pyridylmethyl)amine

    CAS:
    <p>N-Ethyl-N-(3-pyridylmethyl)amine has affinity for nAChR (Ki = 0.97 µM) and can be used in related research in the field of life sciences.</p>
    Fórmula:C8H12N2
    Pureza:99.65%
    Forma y color:Solid
    Peso molecular:136.19
  • Dehydro Aripiprazole (hydrochloride)

    CAS:
    <p>Dehydro aripiprazole, an active atypical antipsychotic metabolite of aripiprazole, is formed by CYP3A4 and CYP2D6.</p>
    Fórmula:C23H26Cl3N3O2
    Forma y color:Solid
    Peso molecular:482.83
  • C175-0062

    CAS:
    <p>C175-0062, a monoamine oxidase B (MAO-B) inhibitor, is applicable in research focused on neurodegenerative disorders such as Parkinson's disease (PD), Alzheimer's disease (AD), and amyotrophic lateral sclerosis (ALS) [1].</p>
    Fórmula:C21H18N2O5
    Forma y color:Solid
    Peso molecular:378.38
  • Stacofylline

    CAS:
    <p>Stacofylline is a xanthine derivative that is used to treat migraine headaches.</p>
    Fórmula:C20H33N7O3
    Pureza:99.54% - >99.99%
    Forma y color:Solid
    Peso molecular:419.52
  • nAChR modulator-1

    CAS:
    <p>nAChR modulator-1, a insecticide, is a insect nAChR orthosteric modulator [1] .</p>
    Fórmula:C12H8ClN3O2
    Forma y color:Solid
    Peso molecular:261.66
  • Neuroprotective Compound Library


    <p>A unique collection of xnum bioactive small molecules with neuroprotective relevance for high throughput screening (HTS) and high content screening (HCS);</p>
    Forma y color:Odour Solid
  • 5-AMAM-2-CP

    CAS:
    <p>5-AMAM-2-CP, a significant metabolite of Acetamiprid, serves as a global insecticide within the neonicotinoid class and acts as an nAChR agonist [1] [2].</p>
    Fórmula:C9H11ClN2O
    Forma y color:Solid
    Peso molecular:198.65
  • Histamine & Melatonin Receptor-Targeted Compound Library


    <p>A unique collection of xnum compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS</p>
    Forma y color:Odour Solid
  • Anisatin


    <p>Anisatin is a useful organic compound for research related to life sciences and the catalog number is T124719.</p>
    Fórmula:C15H20O8
    Forma y color:Solid
    Peso molecular:328.317
  • 2-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione

    CAS:
    <p>2-(2-(1-Benzylpiperidin-4-yl)ethyl)isoindoline-1,3-dione exhibits acetylcholinesterase inhibitory activity with an IC50 of 0.08 µM.</p>
    Fórmula:C22H24N2O2
    Pureza:99.41%
    Peso molecular:348.44
  • hAChE-IN-5


    <p>hAChE-IN-5 (compound 49) is a dual inhibitor of human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBuChE), exhibiting inhibitory potency with</p>
    Pureza:98%
    Forma y color:Odour Solid
  • Nipecotic acid

    CAS:
    <p>Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.</p>
    Fórmula:C6H11NO2
    Forma y color:Off-White To Pale Yellow-Beige Powder
    Peso molecular:129.16
  • AChE-IN-35


    <p>AChE-IN-35 (compound 5g) serves as an acetylcholinesterase inhibitor, exhibiting an inhibitory concentration 50 (IC50) value of 5.88 μM [1].</p>
    Fórmula:C20H16N8O5
    Forma y color:Solid
    Peso molecular:448.39
  • (Iso)-Landipirdine

    CAS:
    <p>(Iso)-Landipirdine((Iso)-RO5025181) is a selective and potent 5-HT6R antagonist.</p>
    Fórmula:C18H19FN2O3S
    Pureza:98.50%
    Forma y color:Soild
    Peso molecular:362.42
  • Perlapine

    CAS:
    <p>Perlapine is an effective and selective HM3DQ DREADD agonist (EC50 = 2.8 nM).</p>
    Fórmula:C19H21N3
    Forma y color:Solid
    Peso molecular:291.39
  • Flufiprole

    CAS:
    <p>Flufiprole is used as a phenylpyrazole pesticide. It has enantioselective metabolism in human and rat liver microsomes.</p>
    Fórmula:C16H10Cl2F6N4OS
    Forma y color:Solid
    Peso molecular:491.24
  • β-Secretase inhibitor-STA

    CAS:
    <p>BACE-IN-1 is amyloid precursor protein beta-secretase inhibitor</p>
    Fórmula:C73H118N16O27
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1651.81
  • AChE/BuChE/MAO-B-IN-2


    <p>AChE/BuChE/MAO-B-IN-2 (compound 4b) is a potent inhibitor of AChE, BuChE, and hu MAO-B, with respective IC50 values of 5.3 μM, 12.4 μM, and 1.9±0.08 μM,</p>
    Fórmula:C19H18FNO3
    Forma y color:Solid
    Peso molecular:327.35
  • AChE-IN-42


    <p>Compound AChE-IN-42, also known as Compound 28, is an acetylcholinesterase (AChE) inhibitor with an inhibition constant (K i) of 0.44 μM [1].</p>
    Forma y color:Odour Solid
  • P-gb-IN-1

    CAS:
    <p>P-gb-IN-1 is a potent P-glycoprotein (P-gp) inhibitor that exhibits reverse activity by inhibiting P-gp outflow.</p>
    Fórmula:C30H28N2O6
    Pureza:99.58%
    Forma y color:Soild
    Peso molecular:512.55
  • PD25


    <p>PD25, an inhibitor of both AChE and BuChE, demonstrates inhibitory constants of hAChE IC50: 1.58 μM, eeAChE IC50: 1.63 μM, and eqBuChE IC50: 2.39 μM.</p>
    Fórmula:C25H24N2O4
    Forma y color:Solid
    Peso molecular:416.47
  • AChE/BChE-IN-13


    <p>AChE/BChE-IN-13 (compound 5j) serves as a potent dual inhibitor of both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), exhibiting half-maximal</p>
    Fórmula:C21H18N8O7
    Forma y color:Solid
    Peso molecular:494.42
  • G923-0271

    CAS:
    <p>G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.</p>
    Fórmula:C28H23FN4O
    Forma y color:Solid
    Peso molecular:450.51
  • Osmanthuside B

    CAS:
    <p>Osmanthuside B, isolated from Pseuderanthemum carruthersii (Seem.) Guill.</p>
    Fórmula:C29H36O13
    Forma y color:Solid
    Peso molecular:592.59
  • BACE1-IN-15


    <p>BACE1-IN-15 (Compound 72) is a selective β-secretase 1 (BACE-1) inhibitor with oral bioavailability and blood-brain barrier permeability, exhibiting an IC50 value of 121.65 nM, and an IC50 of 480.92 nM for BACE-2. BACE1-IN-15 is applicable for research in the field of Alzheimer's disease.</p>
    Forma y color:Odour Solid
  • 5-AAM-2-CP

    CAS:
    <p>5-AAM-2-CP is one of the major metabolites of Acetamiprid. Acetamiprid, a nAChR agonist, is a neonicotinoid insecticide used worldwide.</p>
    Fórmula:C8H9ClN2O
    Pureza:99.58%
    Forma y color:Solid
    Peso molecular:184.62
  • Eletriptan

    CAS:
    <p>Eletriptan, second-generation triptans used to treat migraines, is used as an abortion drug.</p>
    Fórmula:C22H26N2O2S
    Forma y color:Solid
    Peso molecular:382.52
  • Cytidine 5′-diphosphoethanolamine

    CAS:
    <p>Cytidine 5′-diphosphoethanolamine, a key intermediate in phosphatidylethanolamine synthesis, also serves as a stimulant of Ach synthesis [1].</p>
    Fórmula:C11H20N4O11P2
    Forma y color:Solid
    Peso molecular:446.24
  • BuChE-IN-8


    <p>BuChE-IN-8 (compound 19c), a butyrylcholinesterase (BuChE) inhibitor, exhibits an IC50 value of 559 nM and concurrently inhibits human β-secretase (BACE1) and</p>
    Fórmula:C28H33ClN4O2S
    Forma y color:Solid
    Peso molecular:525.11
  • RAGE antagonist peptide

    CAS:
    <p>RAGE antagonist blocks S100P/A4, HMGB-1; hinders glioma growth, metastasis; reduces PDAC cell growth, NF-κB activity; counters TDI effects in mice.</p>
    Fórmula:C57H101N13O17S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1272.56
  • Peptide 401

    CAS:
    <p>Peptide 401: AMP from bee/wasp venom, triggers histamine release, reduces paw swelling.</p>
    Fórmula:C110H192N40O24S4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2587.22
  • COX-2-IN-49


    <p>COX-2-IN-49 (compound 6c) is a potent inhibitor of cyclooxygenase-2 (COX-2), displaying an IC50 value of 2.671 µM. This compound exhibits anti-proliferative properties and holds potential for use in cancer research.</p>
    Forma y color:Odour Solid
  • (R,R)-Palonosetron Hydrochloride

    CAS:
    <p>(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron</p>
    Fórmula:C19H25ClN2O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:332.87
  • CDD0102 HCl

    CAS:
    <p>CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.</p>
    Fórmula:C8H13ClN4O
    Pureza:99.7%
    Forma y color:Soild
    Peso molecular:216.67
  • trans-Cevimeline hydrochloride

    CAS:
    <p>AF 102A hydrochloride is a biochemical.</p>
    Fórmula:C10H18ClNOS
    Forma y color:Solid
    Peso molecular:235.77
  • FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium)


    <p>FITC-β-Ala-Amyloid β-Protein (1-42) (ammonium) is a FITC-labeled amyloid beta monomer, Alzheimer’s research, drug screening, and biomolecular studies.</p>
    Fórmula:C227H330N58O66S2
    Forma y color:Solid
    Peso molecular:4991.53
  • mGluR3 modulator-1

    CAS:
    <p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>
    Fórmula:C16H21N3O
    Pureza:98.99%
    Forma y color:Solid
    Peso molecular:271.36
  • KRP-199 sodium


    <p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>
    Fórmula:C22H12F3N5Na2O7
    Pureza:97.27%
    Forma y color:Soild
    Peso molecular:561.33
  • (Rac)-Sclerone

    CAS:
    <p>(Rac)-Sclerone, a natural product isolated from the green husk of Carya illinoinensis, exhibits significant AChE inhibition activity with an IC50 value of 192.</p>
    Fórmula:C10H10O3
    Forma y color:Solid
    Peso molecular:178.18
  • β-Amyloid (4-10)

    CAS:
    <p>Antibodies corresponding to beta-amyloid (4-10) are effective in vivo inhibitors of cytotoxicity, amyloid plaque formation and special memory disturbances in</p>
    Fórmula:C39H52N12O12
    Pureza:98%
    Forma y color:Solid
    Peso molecular:880.9
  • 5-HT6R antagonist 6


    <p>5-HT6R antagonist 6 (Compound PP15) exhibits high affinity and selectivity for the 5-HT6R receptor, with a Ki of 42 nM. It demonstrates weak antiproliferative activity on tumor cells and low toxicity toward normal cells. 5-HT6R antagonist 6 is applicable in tumor research.</p>
    Fórmula:C24H26N4O2S
    Forma y color:Solid
    Peso molecular:434.55
  • Mosapride citrate dihydrate

    CAS:
    <p>Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.</p>
    Fórmula:C27H35ClFN3O11
    Pureza:98%
    Forma y color:Solid
    Peso molecular:632.04
  • BMY-14802

    CAS:
    <p>BMY-14802 (alpha-(4-fluorophenyl)-4-(5-fluoro-2-pyrimidinyl)-1-piperazine butanol) is a selective and orally active sigma-1 antagonist with an IC50 of 112 nM.</p>
    Fórmula:C18H22F2N4O
    Pureza:99.84%
    Forma y color:Soild
    Peso molecular:348.39
  • TAT-CN21 (scrambled)


    <p>TAT-CN21(scrambled) is a control peptide lacking specific targeting activity and serves as a negative control for TatCN21. TatCN21 is an effective and selective inhibitory peptide for calcium/calmodulin-dependent protein kinase II (CaMKII).</p>
    Forma y color:Odour Solid
  • β-Amyloid (1-38), mouse, rat

    CAS:
    <p>β-Amyloid (1-38), derived from mice and rats, is a chemical compound comprising 38 amino acids, specifically residues 1-38 of the Aβ peptide.</p>
    Forma y color:Solid
  • MAO-IN-6


    <p>MAO-IN-6 (Compound 3f) is a reversible MAO-B inhibitor that can cross the blood-brain barrier, with an IC50 value of 0.09 μM. It also shows inhibitory activity against AChE and BChE, with IC50 values of 4.48 μM and 17.03 μM, respectively. MAO-IN-6 exhibits low cytotoxicity and is applicable in Alzheimer's disease research.</p>
    Fórmula:C22H14F3NO2
    Forma y color:Solid
    Peso molecular:381.35
  • BChE-IN-10

    CAS:
    <p>BChE-IN-10, a strong mixed BChE inhibitor (IC50=6.4 μM), comes from Bletilla striata for AD research.</p>
    Fórmula:C23H20O5
    Forma y color:Solid
    Peso molecular:376.4
  • Exosome Compound Library


    <p>76 exosome-related compounds that can be used for high-throughput and high-content screening.</p>
    Forma y color:Odour Solid
  • 2-Hydroxyalbrassitriol

    CAS:
    <p>2-Hydroxyalbrassitriol (Compound 6) is an AChE inhibitor with an IC 50 of 35.97 μM [1] .</p>
    Fórmula:C15H26O4
    Forma y color:Solid
    Peso molecular:270.36
  • (Rac)-Norcisapride

    CAS:
    <p>Norcisapride, a 5-HT3 and 5-HT4 agonist, treats GI, orofacial, and ENT disorders.</p>
    Fórmula:C14H20ClN3O3
    Pureza:99.32%
    Forma y color:Soild
    Peso molecular:313.78
  • AChE-IN-87


    <p>AChE-IN-87 is an AChE inhibitor with an IC50 of 0.05 μM and a Ki of 16.93 nM. It exhibits no cytotoxicity toward 3T3 cells and is suitable for Alzheimer's disease (AD) research.</p>
    Fórmula:C32H39N3O12S2
    Forma y color:Solid
    Peso molecular:721.19752
  • Orexin B, rat, mouse

    CAS:
    <p>Orexin B, rat, mouse is an endogenous agonist at Orexin receptor with Kis of 420 and 36 nM for OX1 and OX2, respectively.</p>
    Fórmula:C126H215N45O34S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2936.45
  • Anticonvulsant agent 9


    <p>Anticonvulsant agent 9 (compound 4f) is an activator of the α1β2γ2GABA_A receptor, with an EC50 value of 1.24 μM. It inhibits the inactivation of Nav1.2 channels and exhibits significant anticonvulsant activity.</p>
    Fórmula:C22H24N4O2
    Forma y color:Solid
    Peso molecular:376.45
  • MIDD0301

    CAS:
    <p>MIDD0301 is a potent positive allosteric α5β3γ selective GABAA receptor (GABAAR) ligand with EC50 of 17 nM.</p>
    Fórmula:C19H13BrFN3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:414.23
  • AChE/BChE-IN-26


    <p>AChE/BChE-IN-26 (Compound 20aa) is a cholinesterase inhibitor with IC50 values of 0.75 μM for eeAChE and 4.11 μM for eqBChE. This compound possesses antioxidant properties and is applicable in research related to diseases such as Alzheimer's.</p>
    Forma y color:Odour Solid
  • 5-HT1AR/5-HT6R ligand-1


    <p>5-HT1AR/5-HT6R ligand-1 (Compound PP13) functions as a ligand for the 5-HT receptor, demonstrating high affinity for 5-HT1AR, 5-HT6R, and 5-HT7R with Ki values of 19, 69, and 198 nM, respectively. In HEK293 cells, it inhibits cAMP production with EC50 values of 1535, 488, and 53 nM for these receptors. Additionally, 5-HT1AR/5-HT6R ligand-1 exhibits antiproliferative effects on several cancer cell lines, including 1321N1, U87MG, MCF7, and AsPC-1, with IC50 values of 9.6, 13.6, 19.3, and 14.6 μM, respectively. The compound also shows antagonistic activity towards the dopamine receptor D2R, with a Ki of 1903 nM.</p>
    Fórmula:C25H29ClN4O2S
    Forma y color:Solid
    Peso molecular:485.04
  • Dipentylone hydrochloride

    CAS:
    <p>Dipentylone hydrochloride (Bk-dmbdp HCl) is a psychoactive synthetic cathinone and sympathomimetic stimulant. Its inhibitory activity towards the dopamine transporter (IC50=0.233µM) is tenfold higher than that towards NET and SERT, inhibiting dopamine uptake and stimulating locomotor activity in mice.</p>
    Fórmula:C14H20ClNO3
    Pureza:99.94%
    Forma y color:Solid
    Peso molecular:285.77
  • BuChE-IN-13


    <p>BuChE-IN-13 (compound 3) is a BuChE inhibitor that exhibits anti-Alzheimers activity. It is utilized in the research of neurodegenerative diseases.</p>
    Forma y color:Odour Solid
  • Pomaglumetad methionil anhydrous

    CAS:
    <p>LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.</p>
    Fórmula:C12H18N2O7S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:366.41
  • mcK6A1


    <p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>
    Fórmula:C71H99N17O16
    Forma y color:Solid
    Peso molecular:1446.65
  • Pozanicline hydrochloride


    <p>Pozanicline hydrochloride is an oral α4β2 nAChR agonist with a 16.7 nM Ki, insignificantly binding to α7 nAChR.</p>
    Fórmula:C11H17ClN2O
    Pureza:97.13% - 99.81%
    Forma y color:Solid
    Peso molecular:228.72
  • JNJ-67569762

    CAS:
    <p>JNJ-67569762 is a selective BACE1 inhibitor targeting the S3 pocket ( IC 50 = 2.7 nM).</p>
    Fórmula:C22H22F4N4O5S
    Forma y color:Solid
    Peso molecular:530.49
  • (rel)-Asperparaline A

    CAS:
    <p>Aspergillimide, from A. japonicus, inhibits silkworm neuron nAChRs (IC50s: 20.2/39.6 nM), not affecting chicken nAChRs, and paralyzes silkworm larvae.</p>
    Fórmula:C20H29N3O3
    Forma y color:Solid
    Peso molecular:359.47
  • Biotin-β-Amyloid (1-42), human TFA


    <p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>
    Fórmula:C215H326F3N57O64S2
    Forma y color:Solid
    Peso molecular:4854.36
  • AChE/Aβ-IN-6


    <p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>
    Forma y color:Odour Solid
  • AChE-IN-29


    <p>AChE-IN-29, a 3-OH pyrrolidine derivative, acts as a cholinesterase (ChE) inhibitor with potent activity against human acetylcholinesterase (hAChE), electric</p>
    Fórmula:C18H19BrN2O2
    Forma y color:Solid
    Peso molecular:375.26
  • (Rac)-5-Hydroxymethyl Tolterodine hydrochloride

    CAS:
    <p>(Rac)-5-Hydroxymethyl Tolterodine HCl, or (Rac)-Desfesoterodine HCl, is a potent mAChR blocker researched for overactive bladder.</p>
    Fórmula:C22H32ClNO2
    Forma y color:Solid
    Peso molecular:377.95
  • ZL-1101


    <p>ZL-1101 is a human monoclonal antibody (mAb) targeting TNFRSF4/OX40/CD134.</p>
    Forma y color:Odour Liquid
  • BChE-IN-21


    <p>BChE-IN-21, a potent inhibitor of butyrylcholinesterase (BChE), exhibits an inhibition constant (IC50) of 0.14 ± 0.02 μM, indicating promise for research in</p>
    Forma y color:Odour Solid
  • Notch 1 TFA


    <p>Notch 1 TFA encodes a member of the NOTCH family of proteins.</p>
    Fórmula:C64H98N15F3O25S3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1614.81
  • Tampramine

    CAS:
    <p>Tampramine: a TCA and selective norepinephrine inhibitor, with low affinity for other receptors, potential treatment for FST depression.</p>
    Fórmula:C23H24N4
    Pureza:99.87%
    Forma y color:Solid
    Peso molecular:356.46
  • Xanthohumol I


    <p>Xanthohumol I is a natural product that can be used as a reference standard.</p>
    Fórmula:C21H22O6
    Forma y color:Solid
    Peso molecular:370.401
  • AChE-IN-40


    <p>AChE-IN-40 (Compound 5C), with an inhibitory concentration 50 (IC50) of 120 nM, is an acetylcholinesterase (AChE) inhibitor suitable for Alzheimer's disease</p>
    Fórmula:C23H27NO4
    Forma y color:Solid
    Peso molecular:381.46
  • bPiDDB

    CAS:
    <p>bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.</p>
    Fórmula:C24H38Br2N2
    Pureza:98.72%
    Forma y color:Solid
    Peso molecular:514.38
  • Tropicamide

    CAS:
    <p>Tropicamide (Ro 1-7683), a synthetic atropine-like muscarinic antagonist, dilates pupils and paralyzes eye muscles for diagnostic use.</p>
    Fórmula:C17H20N2O2
    Pureza:99.78% - 99.94%
    Forma y color:White Powder
    Peso molecular:284.35
  • β-Amyloid (22-40)

    CAS:
    <p>This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.</p>
    Fórmula:C78H135N21O26S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1815.1
  • Orexin B, rat, mouse TFA


    <p>Orexin B, rat/mouse TFA, activates OX1-R &amp; OX2-R receptors, influencing food intake, energy, and sleep regulation.</p>
    Fórmula:C128H216F3N45O36S
    Forma y color:Solid
    Peso molecular:3050.42
  • (±)-LY367385

    CAS:
    <p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>
    Fórmula:C10H11NO4
    Forma y color:Solid
    Peso molecular:209.201
  • 2'-O-Succinyl-cAMP

    CAS:
    <p>2'-O-Monosuccinyladenosine-3',5'-cyclic monophosphate is an immunogenic derivative of cAMP that has been used to generate anti-cAMP antisera and antibodies.1,2</p>
    Fórmula:C14H16N5O9P
    Forma y color:Solid
    Peso molecular:429.282
  • (Gln22)-Amyloid β-Protein (1-42)

    CAS:
    <p>(Gln22)-Amyloid β-Protein (1-42), a Dutch mutation (E22Q) variant of β-Amyloid (1-42), demonstrates increased fibrillogenic and pathogenic characteristics [1].</p>
    Fórmula:C203H312N56O59S
    Forma y color:Solid
    Peso molecular:4513.05
  • MPPG

    CAS:
    <p>MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).</p>
    Fórmula:C9H12NO5P
    Forma y color:Solid
    Peso molecular:245.171
  • BuChE-IN-16


    <p>BuChE-IN-16 (Compound 6a) is an orally active, blood-brain barrier-permeable, and selective BuChE inhibitor with an IC50 of 0.33 μM. It exhibits anti-inflammatory and neuroprotective effects, improves cognitive function in Alzheimer's disease (AD) zebrafish models, and alleviates scopolamine-induced memory impairment in mice. BuChE-IN-16 is applicable for Alzheimer's disease research.</p>
    Fórmula:C16H22N2O3
    Forma y color:Solid
    Peso molecular:290.36
  • Tiflucarbine

    CAS:
    <p>Tiflucarbine is a potential non-selective 5-HT agonist with antidepressant activity.Tiflucarbine dose-dependently increased the specific activity of soluble</p>
    Fórmula:C16H17FN2S
    Pureza:>99.99%
    Forma y color:Solid
    Peso molecular:288.38
  • α5-GABAA receptor modulator 1


    <p>α5-GABAA receptor modulator 1 (Compound A-4) is a selective silent allosteric modulator (SAM) targeting the α5 subunit of GABAA receptors, useful for research into central nervous system (CNS) disorders.</p>
    Fórmula:C21H20FN3O4
    Forma y color:Solid
    Peso molecular:397.4
  • hAChE-IN-4


    <p>Compd 5d (hAChE-IN-4) is a potent hAChE inhibitor that readily crosses the blood-brain barrier, exhibiting an IC50 of 0.25 μM, and is utilized in the study of</p>
    Fórmula:C30H23Cl3N2O3
    Forma y color:Solid
    Peso molecular:565.87
  • NMDAR antagonist 2


    <p>NMDAR antagonist 2 (compound 3I) is a blood-brain barrier permeable antagonist of NMDA receptors, exhibiting IC50 values of 4.42 μM and 214.75 μM at membrane potentials of -60 mV and 40 mV, respectively, for hGluN1/hGluN2A. This compound has been shown to mitigate hippocampal damage.</p>
    Fórmula:C17H20ClNO
    Forma y color:Solid
    Peso molecular:289.8
  • SAHM1

    CAS:
    <p>Notch pathway inhibitor - stabilized hydrocarbon-stapled alpha helical peptide. Targets the protein-protein interface and prevents Notch complex assembly.</p>
    Fórmula:C94H162N36O23S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2196.58
  • Anticonvulsant agent 8


    <p>Anticonvulsant agent 8 (compound D4) is a chemical used in treating epilepsy by inhibiting GABAA currents. In mouse models, its ED50 values are 2.23 mg/kg for the maximal electroshock (MES) test and 24.60 mg/kg for the pentylenetetrazol (PTZ) test.</p>
    Fórmula:C15H11N5O
    Forma y color:Solid
    Peso molecular:277.28
  • Rasagiline 13C3 mesylate racemic

    CAS:
    <p>Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.</p>
    Fórmula:C13H17NO3S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:270.32
  • TB-11

    CAS:
    <p>TB-11 is an inhibitor of Cathepsin D with IC50 values of 0.126 nM (Cathepsin D), 1.92 nM (Cathepsin E), and 48.8 nM (BACE1). It is primarily utilized in oncological research.</p>
    Fórmula:C52H78N8O12
    Forma y color:Solid
    Peso molecular:1007.22
  • Galanin (1-15) (porcine, rat)

    CAS:
    <p>N-terminal galanin fragment used to mediate central cardiovascular effects</p>
    Fórmula:C72H105N19O20
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1556.72
  • PD07


    <p>PD07 is an orally active acetylcholinesterase (AChE) inhibitor, exhibiting an IC50 of 0.29 μM against human AChE, and demonstrates inhibition of cholinesterases</p>
    Fórmula:C23H21ClN2O4
    Forma y color:Solid
    Peso molecular:424.88
  • hAChE/hBuChE/GSK-3β-IN-1


    <p>hAChE/hBuChE/GSK-3β-IN-1 (Compound 6c) is a multi-target compound designed for Alzheimer's treatment capable of crossing the blood-brain barrier. It inhibits hAChE with an IC50 of 28.88 nM, hBuChE with an IC50 of 131.90 nM, and GSK-3β with an IC50 of 51.42 nM. Additionally, it acts as an inhibitor of tau protein and Aβ protein aggregation.</p>
    Fórmula:C19H15NO4
    Forma y color:Solid
    Peso molecular:321.327
  • CVN417


    <p>CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion.</p>
    Forma y color:Odour Solid
  • Navicixizumab

    CAS:
    <p>Navicixizumab, a bispecific VEGF/DLL4 inhibitor, pairs with Paclitaxel in ovarian and other cancer research.</p>
    Forma y color:Liquid
  • Isobutyryl-L-carnitine

    CAS:
    <p>Isobutyryl-L-carnitine is a member of the class of compounds known as acylcarnitines. Isobutyryl-L-carnitine is a product of the acyl-CoA dehydrogenases.</p>
    Fórmula:C11H21NO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:231.29
  • Rivanicline 2HCl


    <p>Rivanicline 2HCl is a selective neuronal nicotinic receptor inhibitor with a high affinity for the α4β2 subtype.</p>
    Fórmula:C10H16Cl2N2
    Pureza:99.4%
    Forma y color:Soild
    Peso molecular:235.15
  • CZC-54252 hydrochloride

    CAS:
    <p>CZC-54252 hydrochloride: selective LRRK2 inhibitor; IC50 = 1.85/1.28 nM (wild-type/G2019S); neuroprotective; EC50 = 1 nM for G2019S injury.</p>
    Fórmula:C22H26Cl2N6O4S
    Pureza:98.21%
    Forma y color:Solid
    Peso molecular:541.45
  • GABA-A Receptor Ligand-1


    <p>GABA-A Receptor Ligand-1 (Compound 4) is a ligand for the GABA-A receptor with a pKi of 7.27. It alleviates mitochondrial dysfunction, promotes neurite outgrowth and neuronal regeneration, and demonstrates neuroprotective effects in a rat ischemic stroke model.</p>
    Fórmula:C20H20FN3O
    Forma y color:Solid
    Peso molecular:337.391
  • RA306


    <p>RA306 is an orally active CAMK2 inhibitor that effectively disrupts the PEAK1/CAMK2 signaling pathway. It demonstrates anti-tumor activity by inhibiting proliferation, migration, and invasion of breast cancer cells. Additionally, RA306 shows potential in cardiac disease research, as it improves dilated cardiomyopathy in mice.</p>
    Forma y color:Odour Solid
  • Sulamserod

    CAS:
    <p>Sulamserod (RS 100302) is a potent 5-HT4 receptor antagonist with antiarrhythmic activity for the study of atrial fibrillation and cardiovascular related</p>
    Fórmula:C19H28ClN3O5S
    Pureza:98.76%
    Forma y color:Solid
    Peso molecular:445.96
  • Alosetron

    CAS:
    <p>Alosetron, a 5-HT3 antagonist, is used for the management of severe diarrhea-predominant irritable bowel syndrome (IBS) in women only.</p>
    Fórmula:C17H18N4O
    Pureza:98%
    Forma y color:Crystalline Powder
    Peso molecular:294.36
  • Moxonidine hydrochloride

    CAS:
    <p>Moxonidine Hydrochloride: selective I1 imidazoline receptor agonist, stronger than α2-AR; lowers blood pressure; central action.</p>
    Fórmula:C9H13Cl2N5O
    Forma y color:Solid
    Peso molecular:278.14
  • ZZL-7

    CAS:
    <p>ZZL-7 is a rapid antidepressant targeting nNOS &amp; SERT in DRN, crosses blood-brain barrier, with MDD research potential.</p>
    Fórmula:C11H20N2O4
    Pureza:99.79%
    Forma y color:Soild
    Peso molecular:244.29
  • Aβ-IN-8


    <p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>
    Fórmula:C22H16F3N3O3S
    Forma y color:Solid
    Peso molecular:459.44
  • EB-42486

    CAS:
    <p>EB-42486 is an effective and highly selective inhibitor of G2019S-LRRK2 with an IC50 &lt; 0.2 nM.</p>
    Fórmula:C22H22N8O
    Pureza:99.53%
    Forma y color:Solid
    Peso molecular:414.46
  • PSEN1-IN-1


    <p>PSEN1-IN-1 (Compound (+)-13b) functions as an inhibitor of PSEN1, displaying potent inhibition of the PSEN1-APH1A and PSEN1-APH1B complexes with respective IC50</p>
    Fórmula:C20H19ClF3NO3S
    Forma y color:Solid
    Peso molecular:445.88
  • Nitrazolam

    CAS:
    <p>Nitrazolam is a benzodiazepine compound that may exhibit central nervous system depressant properties similar to traditional benzodiazepine drugs by acting on the GABA receptors (GABA receptor). These effects include sedation, hypnosis, anxiolytic, and anticonvulsant activities.</p>
    Fórmula:C17H13N5O2
    Forma y color:Solid
    Peso molecular:319.32
  • AMI-193

    CAS:
    <p>AMI-193 (Spiramide) is a selective 5-HT2 &amp; D2 receptor antagonist with antipsychotic properties.</p>
    Fórmula:C22H26FN3O2
    Pureza:99.65%
    Forma y color:Solid
    Peso molecular:383.46
  • Desfesoterodine

    CAS:
    <p>Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.</p>
    Fórmula:C22H31NO2
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:341.49
  • L-689560

    CAS:
    <p>L-689560, a radiolabeled ligand, studies NMDA receptors, is an antagonist at GluN1 glycine site.</p>
    Fórmula:C17H15Cl2N3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:380.23
  • Neocarzinostatin

    CAS:
    <p>Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic.</p>
    Pureza:98%
    Forma y color:Solid
    Peso molecular:N/A
  • Paynantheine

    CAS:
    <p>Paynantheine is an alkaloid with antinociceptive properties, found in Mitragyna speciosa. It also acts as an agonist at 5-HT1AR and 5-HT2BR receptors, inducing lower lip contraction and providing antinociception in rats.</p>
    Fórmula:C23H28N2O4
    Forma y color:Solid
    Peso molecular:396.48
  • 5-MeO-pyr-T

    CAS:
    <p>5-MeO-pyr-T (5-Methoxy pyrrolidinyltryptamine) acts as a 5-HT1AR agonist, exhibiting Ki values of 0.577 μM and 373 μM for 5-HT1AR and 5-HT2AR, respectively. It inhibits the reuptake of 5-HT and triggers its release. Additionally, 5-MeO-pyr-T can induce reduced motor activity.</p>
    Fórmula:C15H20N2O
    Forma y color:Solid
    Peso molecular:244.33
  • AChE/BChE-IN-15


    <p>AChE/BChE-IN-15 (Compound 6d) serves as an inhibitor for both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), presenting inhibition constants (</p>
    Fórmula:C29H30N6O3
    Forma y color:Solid
    Peso molecular:510.59
  • UCM 549

    CAS:
    <p>UCM 549 is a bioactive chemical.</p>
    Fórmula:C19H21NO2
    Forma y color:Solid
    Peso molecular:295.38
  • α-Conotoxin imi

    CAS:
    <p>alpha-Conotoxin imi is a nicotinic acetylcholine receptor ligand.</p>
    Fórmula:C52H78N20O15S4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1351.56
  • DSP-1053

    CAS:
    <p>Dsp-1053 is a powerful SERT (Ki=1.02 nM) inhibitor with partial 5-HT1A receptor (Ki=5.05 nM) agonizing activity.</p>
    Fórmula:C26H32BrNO4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:502.44
  • β-Amyloid (1-17)

    CAS:
    <p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>
    Fórmula:C90H130N28O29
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2068.2
  • Alosetron-d3

    CAS:
    <p>Alosetron D3 (GR 68755 D3) is a deuterium-labeled Alosetron. Alosetron is an antagonist of 5HT3-receptor.</p>
    Fórmula:C17H18N4O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:297.37
  • Duloxetine D3 hydrochloride

    CAS:
    <p>Duloxetine D3 HCl is a deuterium-labeled SNRI, treats depression/GAD, Ki 4.6 nM.</p>
    Fórmula:C18H20ClNOS
    Pureza:98%
    Forma y color:Solid
    Peso molecular:336.89
  • Acetyl-Tau Peptide (273-284) amide

    CAS:
    <p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>
    Fórmula:C64H116N18O17
    Forma y color:Solid
    Peso molecular:1409.72
  • Cloxacepride

    CAS:
    <p>cloxacepride is a CaM antagonist that is used to treat asthma disease.</p>
    Fórmula:C22H27Cl2N3O4
    Pureza:99.62%
    Forma y color:Solid
    Peso molecular:468.37
  • R-(+)-Cotinine

    CAS:
    <p>R-(+)-Cotinine, an inactive nicotine metabolite, boosts Ach-induced current in human α7 nAChRs.</p>
    Fórmula:C10H12N2O
    Forma y color:Solid
    Peso molecular:176.22
  • Atracurium

    CAS:
    <p>Atracurium (BW-33A) is a competitive AChR antagonist and non-depolarizing muscle relaxant that may cause bronchoconstriction.</p>
    Fórmula:C53H72N2O122
    Forma y color:Solid
    Peso molecular:929.14
  • BChE-IN-12

    CAS:
    <p>BChE-IN-12, non-competitive BChE inhibitor from Bletilla striata, IC50=2.3μM; potential Alzheimer’s research.</p>
    Fórmula:C31H30O5
    Forma y color:Solid
    Peso molecular:482.57
  • MGS0028

    CAS:
    <p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>
    Fórmula:C8H8FNO5
    Forma y color:Solid
    Peso molecular:217.15
  • AChE-IN-4


    <p>AChE-IN-4 is an acetylcholine esterase inhibitor (AChEI) with an IC50 value of 24.1 μM.</p>
    Fórmula:C32H25BrN6O4S
    Forma y color:Solid
    Peso molecular:669.55
  • BuChE-IN-21


    <p>BuChE-IN-21 (compound SXF3) is a potent and selective inhibitor of BuChE, demonstrating inhibitory effects on eqBuChE and hBuChE with IC50 values of 0.05 and 0.04 μM, respectively. Additionally, BuChE-IN-21 exhibits significant anti-inflammatory activity.</p>
    Fórmula:C16H23NO2
    Forma y color:Solid
    Peso molecular:261.17288
  • β-Amyloid (13-27)

    CAS:
    <p>β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.</p>
    Fórmula:C84H126N24O24
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1856.05
  • 5-HT2A receptor agonist-5

    CAS:
    <p>5-HT2A receptor agonist-5 (compound I-3) is a potent 5-HT2A agonist with a Ki value of 0.017 µM and exhibits antidepressant activity.</p>
    Fórmula:C23H29N3O
    Forma y color:Solid
    Peso molecular:363.5
  • β-Amyloid (1-43)(human) TFA


    <p>β-Amyloid (1-43)(human) TFA exhibits greater aggregation tendencies and heightened toxicity compared to its well-established counterpart, Aβ1-42.</p>
    Fórmula:C209H319F3N56O64S
    Forma y color:Solid
    Peso molecular:4729.21
  • M 8218

    CAS:
    <p>M 8218 is a bioactive chemical.</p>
    Fórmula:C20H29NO2
    Forma y color:Solid
    Peso molecular:315.45
  • 2-Methyl-1-indanone

    CAS:
    <p>2-Methyl-1-indanone is an acetylcholinesterase inhibitor and can be used for biochemical experiments and drug synthesis.</p>
    Fórmula:C10H10O
    Pureza:96.6%
    Forma y color:Solid
    Peso molecular:146.19
  • 4-Butyl-α-agarofuran

    CAS:
    <p>4-Butyl-alpha-agarofuran, a Gharu-wood derivative, is an anxiolytic, antidepressant, and aids neurological research.</p>
    Fórmula:C18H30O
    Forma y color:Solid
    Peso molecular:262.43
  • Sintamil

    CAS:
    <p>Sintamil is a useful organic compound for research related to life sciences. The catalog number is T71697 and the CAS number is 16398-39-3.</p>
    Fórmula:C18H20ClN3O4
    Forma y color:Solid
    Peso molecular:377.82
  • p-HTAA

    CAS:
    <p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>
    Fórmula:C24H16O4S5
    Forma y color:Solid
    Peso molecular:528.71
  • Cannabidiolic acid methyl ester

    CAS:
    <p>Cannabidiolic acid methyl ester (HU-580) is an orally active analogue of cannabidiolic acid. It enhances the activation of 5-HT1A receptors and increases the expression of c-Fos and NeuN in specific hypothalamic nuclei in rats. Cannabidiolic acid methyl ester exhibits anti-nausea, anxiolytic, and anti-nociceptive effects.</p>
    Fórmula:C23H32O4
    Forma y color:Solid
    Peso molecular:372.5
  • Deoxynojirimycin Tetrabenzyl Ether

    CAS:
    <p>Deoxynojirimycin tetrabenzyl ether aids in making 1-dNM, a strong α-glucosidase I &amp; II blocker.</p>
    Fórmula:C34H37NO4
    Forma y color:Solid
    Peso molecular:523.673
  • β-Amyloid (1-34)

    CAS:
    <p>This is a fragment of beta-amyloid peptide. It has amino acids 1 through 34.</p>
    Fórmula:C170H253N47O52
    Pureza:98%
    Forma y color:Solid
    Peso molecular:3787.2
  • N-Methylcyclohexaneethaneamine

    CAS:
    <p>N-Methylcyclohexaneethaneamine is a useful organic compound for research related to life sciences.</p>
    Fórmula:C9H19N
    Forma y color:Solid
    Peso molecular:141.2539
  • CUR-IPA


    <p>CUR-IPA is a cholinesterase inhibitor with IC50 values of 5.99 μM for eAChE (electric eel), 59.30 μM for hAChE (human), and 60.66 μM for hBChE (human). It has free radical scavenging and antioxidant activity and is useful for researching cognitive dysfunction.</p>
    Fórmula:C43H38N2O8
    Forma y color:Solid
    Peso molecular:710.77
  • FRM-024

    CAS:
    <p>FRM-024 is a powerful gamma secretase modulator with the ability to penetrate the central nervous system (CNS), designed specifically for the treatment of</p>
    Fórmula:C22H22ClN5O2
    Forma y color:Solid
    Peso molecular:423.9
  • Withasomniferolide B

    CAS:
    <p>Withasomniferolide B, a withanolide from Withania somnifera root, activates GABAA receptors.</p>
    Fórmula:C28H36O4
    Forma y color:Solid
    Peso molecular:436.58
  • BSB

    CAS:
    <p>BSB is a Congo red-derived fluorescent probe, an amyloid protein imaging agent, interacting with amyloid fibrils formed by Aβ (1-40) peptides in rodents.</p>
    Fórmula:C24H17BrO6
    Pureza:95.53%
    Forma y color:Solid
    Peso molecular:481.29
  • (Glu20)-Amyloid β-Protein (1-42)

    CAS:
    <p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>
    Fórmula:C199H309N55O62S
    Forma y color:Solid
    Peso molecular:4495.98
  • α-Conotoxin PIA

    CAS:
    <p>Selective antagonist of α6-containing nicotinic receptors that discriminates between the closely related α6 and α3 subunits (IC50 values are 0.95 and 74.2 nM</p>
    Fórmula:C79H125N27O25S4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1981.3