Neurociencia
Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.
Subcategorías de "Neurociencia"
- Receptor 5-HT(940 productos)
- ACK(1 productos)
- AChR(574 productos)
- ATP Citrato Liasa(16 productos)
- Receptor adrenérgico(2.942 productos)
- BACE(36 productos)
- Beta amiloide(204 productos)
- CAMK(68 productos)
- Inhibidores de ciclooxigenasa (COX)(562 productos)
- Receptor de dopamina(407 productos)
- Receptor GABA(336 productos)
- Gamma-secretasa(59 productos)
- GluR(255 productos)
- GlyT(24 productos)
- Receptor de histamina(358 productos)
- LRRK2(33 productos)
- Receptor de melatonina(24 productos)
- NMDAR(28 productos)
- Receptor de OX(40 productos)
- Receptor de opioides(296 productos)
Mostrar 12 subcategorías más
Se han encontrado 5400 productos de "Neurociencia"
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Rislenemdaz
CAS:<p>Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).</p>Fórmula:C19H23FN4O2Pureza:98.18%Forma y color:SolidPeso molecular:358.41BuChE-IN-TM-10
CAS:<p>TM-10: Potent BuChE inhibitor, IC50 8.9 nM, disaggregates Aβ, antioxidant, BBB penetrant, may treat Alzheimer's.</p>Fórmula:C32H38N2O3Pureza:99.54%Forma y color:SolidPeso molecular:498.66Atabecestat
CAS:<p>Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.</p>Fórmula:C18H14FN5OSPureza:99.21% - 99.77%Forma y color:SolidPeso molecular:367.4JNJ-42253432
CAS:<p>JNJ-42253432 is an oral active P2X7 antagonist capable of penetrating the central nervous system with a pKi value of 9.1 for rat and 7.9 for human P2X7 channels</p>Fórmula:C28H38N4OPureza:99.98%Forma y color:SolidPeso molecular:446.63Osemozotan HCl
CAS:<p>Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.</p>Fórmula:C19H22ClNO5Pureza:98.87% - 99.63%Forma y color:SolidPeso molecular:379.84Didesmethyl cariprazine
CAS:<p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>Fórmula:C19H28Cl2N4OPureza:99.52%Forma y color:SolidPeso molecular:399.36SB 216641 hydrochloride
CAS:<p>SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.</p>Fórmula:C28H31ClN4O4Pureza:98.06% - 99.23%Forma y color:SolidPeso molecular:523.02Philanthotoxin 74 dihydrochloride
CAS:<p>Philanthotoxin 74 dihydrochloride is an antagonist of AMPAR with IC50s of 263 and 296 nM for GluR3 and GluR1.</p>Fórmula:C24H44Cl2N4O3Pureza:99.75%Forma y color:SolidPeso molecular:507.54AMPA receptor modulator-1
CAS:<p>AMPA receptor modulator-1 can be activated by glutamate, thereby modulating ion channels.</p>Fórmula:C16H11ClF3NO2Pureza:99.93%Forma y color:SolidPeso molecular:341.71Dalzanemdor
CAS:<p>Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive</p>Fórmula:C27H43F3O2Pureza:98.2% - >99.99%Forma y color:SolidPeso molecular:456.62VU6004909
CAS:<p>VU6004909 is an mGlu5 receptor orthosteric modulator that reverses MK801-induced increased cortical activity and cognitive dysfunction.</p>Fórmula:C21H15FN2O4Pureza:96.68% - 98.44%Forma y color:SolidPeso molecular:378.35AMPA receptor antagonist-3
CAS:<p>AMPA receptor antagonist-3 is an AMPA receptor antagonist.</p>Fórmula:C20H19N5O2SPureza:99.79%Forma y color:SolidPeso molecular:393.46R-(+)-EU-1180-453
CAS:<p>R-(+)-EU-1180-453 is a novel GluN2C/D selective NMDAR-positive modulator for the study of neurological disorders.</p>Fórmula:C22H21FN2O3Pureza:99.63%Forma y color:SolidPeso molecular:380.41TZ3O
CAS:<p>TZ3O is an anticholinergic compound with neuroprotective activity.TZ3O ameliorates memory impairment in Scopolamine-induced Alzheimer's type model in rats.</p>Fórmula:C18H13NO4SPureza:99.84%Forma y color:SolidPeso molecular:339.37γ-Secretase-IN-1
CAS:<p>γ-Secretase-IN-1 is a γ-secretase inhibitor that displays partial antiproliferative activity against T-47D cells.</p>Fórmula:C27H24F2N4O3Pureza:99.56%Forma y color:SolidPeso molecular:490.5Gossypolone
CAS:<p>Gossypolone is is a proposed major metabolite of gossypol. Gossypolone reduces Notch/Wnt signaling and induces apoptosis.</p>Fórmula:C30H26O10Pureza:96.66%Forma y color:SolidPeso molecular:546.52CGP 78608 hydrochloride
CAS:<p>CGP 78608 hydrochloride: NMDA receptor antagonist (IC50=6 nM), anticonvulsant, enhances GluN1/GluN3A currents (EC50=26.3 nM).</p>Fórmula:C11H14BrClN3O5PPureza:99.85%Forma y color:SolidPeso molecular:414.58Tematropium
CAS:<p>Tematropium (CDDD3602) possesses anticholinergic effects and can be used in neurological studies.</p>Fórmula:C21H31NO8SPureza:99.89%Forma y color:SolidPeso molecular:457.54WAY-607695
CAS:<p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>Fórmula:C13H12FNO2Pureza:99.82%Forma y color:SolidPeso molecular:233.24SB-616234-A
CAS:<p>SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.</p>Fórmula:C32H36ClN5O3Pureza:99.72%Forma y color:SolidPeso molecular:574.11PXS-5153A
CAS:<p>PXS-5153A rapidly inhibits lysyl oxidase 2/3 enzymes, blocks activity in 15 mins, and reduces fibrosis.</p>Fórmula:C20H25Cl2FN4O2SPureza:99.58%Forma y color:SolidPeso molecular:475.41BMS-986176
CAS:<p>AAK1-IN-1 is a highly selective and potent inhibitor of adaptor associated kinase 1 (AAK1, IC50 = 2 nM).</p>Fórmula:C19H23F4N3OPureza:98.58% - 98.7%Forma y color:SolidPeso molecular:385.4Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Fórmula:C24H28FN3OPureza:99.68% - 99.91%Forma y color:SolidPeso molecular:393.5MDR-1339
CAS:<p>MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.</p>Fórmula:C20H22O4Pureza:98.57%Forma y color:SolidPeso molecular:326.39PXS-5120A
CAS:<p>PXS-5120A is an irreversible fluoroallylamine Lysyl Oxidase-like 2/3 (LOXL2/3) inhibitor with anti-fibrotic activity.</p>Fórmula:C22H25ClFN3O4SPureza:97.02%Forma y color:SolidPeso molecular:481.97CVN636
CAS:<p>CVN636, a potent and selective allosteric agonist for the mGluR7 receptor, exhibits oral activity and CNS permeability [1], with an EC50 of 7 nM for human</p>Fórmula:C19H20FNO4SForma y color:SolidPeso molecular:377.43Mesulergine hydrochloride
CAS:<p>5-HT2A and 2C receptor antagonist</p>Fórmula:C18H27ClN4O2SPureza:98%Forma y color:SolidPeso molecular:398.95AChE/BuChE-IN-3
CAS:<p>AChE/BuChE-IN-3 inhibits AChE (IC50: 0.65 μM), BuChE (IC50: 5.77 μM), crosses BBB, and hinders Aβ1-42 aggregation for Alzheimer's research.</p>Fórmula:C30H30F3N3O6Forma y color:SolidPeso molecular:585.57HDAC6-IN-9
CAS:<p>HDAC6-IN-9 is a γ-secretase modulator that can significantly reduce the level of Aβ42 in mouse brain and can be used to study neurological diseases.</p>Fórmula:C19H16N2O3Pureza:98.84%Forma y color:SolidPeso molecular:320.34Revexepride
CAS:<p>Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.</p>Fórmula:C21H32ClN3O4Pureza:98%Forma y color:SolidPeso molecular:425.95Rodatristat ethyl
CAS:<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Fórmula:C29H31ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:590.04AChE-IN-11
<p>AChE-IN-11 aids Alzheimer's research, has neuroprotection/antioxidant properties (ORAC=2.5), and acts on AChE, MAO-B, BACE1 with IC50 values of 7.9-9.9 μM.</p>Fórmula:C18H28N2O4Forma y color:SolidPeso molecular:336.43AChE-IN-83
CAS:<p>AChE-IN-83 (compound f1) is an AChE inhibitor that suppresses nematode growth and acetylcholinesterase activity in rice seeds while being safe for the seeds. It specifically targets Aphelenchoides besseyi, with an LC50 of 19.0 μg/mL over 48 hours. AChE-IN-83 impedes nematode populations and behaviors in rice seeds, damages the nematode cuticle, and induces reactive oxygen species, lipofuscin, and lipid generation within the nematodes.</p>Fórmula:C10H7ClN2O2SForma y color:SolidPeso molecular:254.6935-HT1A modulator 4
CAS:<p>5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.</p>Fórmula:C9H14N4Forma y color:SolidPeso molecular:178.234MMB-4
CAS:<p>MMB-4 is an oxime that can reactivate cholinesterases (cholinesterases) which have been inactivated due to exposure to organophosphates such as Sarin or Soman.</p>Fórmula:C13H14Br2N4O2Forma y color:SolidPeso molecular:418.084MAO-B-IN-40
CAS:<p>MAO-B-IN-40 (3a) is an inhibitor of MAOB, exhibiting an IC50 value of 0.493 μM against hMAOB, and demonstrates significant neuroprotective and antioxidant effects. MAO-B-IN-40 (3a) is applicable in Parkinson's disease research.</p>Fórmula:C17H15N3O3Forma y color:SolidPeso molecular:309.319THRX-194556
CAS:<p>THRX-194556 is an agonist of the 5-HT4 receptor. It is applicable in the study of gastrointestinal functional disorders and Alzheimer's disease.</p>Fórmula:C28H41N5O5SForma y color:SolidPeso molecular:559.721GABAA receptor agonist 1
<p>Compound 3e, a potent GABAA agonist, targets GABA sites and has potential anti-depressive effects in mice.</p>Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.45FCOB02
CAS:<p>FCOB02 is a monoamine oxidase B (MAO-B) ligand. It can be labeled as [18F]FCOB02, serving as a 4-methylcoumarin-like targeting probe. [18F]FCOB02 demonstrates high affinity for MAO-B, with an IC50 of 10.68 nM. It is utilized for specific imaging and quantitative analysis of MAO-B in vivo.</p>Fórmula:C16H12FNO3Forma y color:SolidPeso molecular:285.27hAChE/Aβ1-42-IN-1
CAS:<p>Compound 16 (hAChE/Aβ1-42-IN-1) is a potent inhibitor targeting both hAChE and Aβ1-42 aggregation, demonstrating considerable safety in hepG2 cell lines and</p>Fórmula:C20H24N6OForma y color:SolidPeso molecular:364.44Aβ-IN-2
<p>Aβ-IN-2 is a peptide inhibitor of Aβ1-42.</p>Fórmula:C37H51NOForma y color:SolidPeso molecular:525.81LP 12 hydrochloride hydrate
<p>LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.</p>Fórmula:C32H39N3O·HCl·xH2OForma y color:SolidAChE-IN-24
<p>AChE-IN-24: Strong AChE blocker, crosses blood-brain barrier, IC50=0.053 μM, useful for AD research.</p>Fórmula:C22H30N2O4S2Forma y color:SolidPeso molecular:450.61LRRK2-IN-4
CAS:<p>LRRK2-IN-4: Potent, selective LRRK2 inhibitor, oral, BBB-penetrating, IC50=2.6 nM, potential for Parkinson's.</p>Fórmula:C25H29ClF2N6O2Forma y color:SolidPeso molecular:518.99cSPM
<p>cSPM (Cyclic spermine) is an Aβ42 inhibitor. cSPM inhibits the aggregation of three different peptides, Aβ42, tryptophan and insulin, and reduces cytotoxicity.</p>Fórmula:C27H57N7Forma y color:SolidPeso molecular:479.79(+)-Sparteine sulfate pentahydrate
<p>(+)-sparteine (sulfate pentahydrate) is a ganglion blocker that competitively blocks nicotinic acetylcholine receptors in neurons.</p>Fórmula:C15H38N2O9SForma y color:SolidPeso molecular:422.54Befiradol hydrochloride
CAS:<p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>Fórmula:C20H23Cl2F2N3OPureza:99.1%Forma y color:SolidPeso molecular:430.32K203
<p>K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.</p>Fórmula:C16H18Br2N4O2Forma y color:SolidPeso molecular:458.15Monoamine Oxidase B inhibitor 2
<p>MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.</p>Fórmula:C19H19FO3Forma y color:SolidPeso molecular:314.35nAChR antagonist 1
CAS:<p>Compound B15, a potent α7 nAChR antagonist, IC50 = 3.3 μM, promising for research on schizophrenia, Alzheimer's, and inflammation.</p>Fórmula:C19H22N4O2Forma y color:SolidPeso molecular:338.4
