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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5400 productos de "Neurociencia"

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  • Tribendimidine

    CAS:
    <p>Tribendimidine: broad-spectrum oral anthelmintic, nAChR agonist, effective against A. lumbricoides and N. americanus.</p>
    Fórmula:C28H32N6
    Pureza:≥98%
    Forma y color:Solid
    Peso molecular:452.59
  • Adoprazine

    CAS:
    <p>Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.</p>
    Fórmula:C24H24FN3O2
    Pureza:99.83%
    Forma y color:Solid
    Peso molecular:405.46
  • SCH-900271

    CAS:
    <p>SCH-900271 treats dyslipidemia by targeting nicotinic acid receptors, addressing hyperlipidaemia.</p>
    Fórmula:C14H16N2O4
    Pureza:98.82% - 99.93%
    Forma y color:Solid
    Peso molecular:276.29
  • Masupirdine free base

    CAS:
    <p>Masupirdine free base (SUVN-502 free base) is a 5-HT6 receptor antagonist that can be used to study neurological disorders like Alzheimer's disease.</p>
    Fórmula:C21H24BrN3O3S
    Pureza:98.36% - 99.65%
    Forma y color:Solid
    Peso molecular:478.4
  • Faxeladol

    CAS:
    <p>Faxeladol: adrenergic, serotonin inhibitor &amp; opioid agonist for neurological studies.</p>
    Fórmula:C15H23NO
    Pureza:98.09% - 98.77%
    Forma y color:Solid
    Peso molecular:233.35
  • CPCCOEt

    CAS:
    <p>CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b</p>
    Fórmula:C13H13NO4
    Pureza:99.91%
    Forma y color:Solid
    Peso molecular:247.25
  • Tedatioxetine

    CAS:
    <p>Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.</p>
    Fórmula:C18H21NS
    Pureza:99.76% - >99.99%
    Forma y color:Solid
    Peso molecular:283.43
  • Golexanolone

    CAS:
    <p>Golexanolone can be used to study neurological diseases.</p>
    Fórmula:C21H31NO2
    Pureza:99.90% - 99.99%
    Forma y color:Solid
    Peso molecular:329.48
  • Femoxetine hydrochloride

    CAS:
    <p>Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.</p>
    Fórmula:C20H26ClNO2
    Pureza:99.63%
    Forma y color:Solid
    Peso molecular:347.88
  • Tiospirone

    CAS:
    <p>Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and a dopamine blocker used in the study of neurological disorders such as schizophrenia.</p>
    Fórmula:C24H32N4O2S
    Pureza:99.74%
    Forma y color:Solid
    Peso molecular:440.6
  • NNC 05-711

    CAS:
    <p>NNC 05-711 (NO-711 hydrochloride) is a potent and selective inhibitor of GAT-1 (GABA transporter 1), exerting anticonvulsant and analgesic effects.</p>
    Fórmula:C21H23ClN2O3
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:386.87
  • Adenylyl cyclase-IN-1

    CAS:
    <p>Adenylyl cyclase-IN-1 is a potential adenylyl cyclase inhibitor for ocular hypotonia research [1].</p>
    Fórmula:C9H8N2S3
    Forma y color:Solid
    Peso molecular:240.37
  • VU0029251

    CAS:
    <p>VU0029251 serves as a partial antagonist of mGluR5, exhibiting a binding affinity with a K i of 1.07 μM.</p>
    Fórmula:C10H11N3S2
    Forma y color:Solid
    Peso molecular:237.34
  • AChE-IN-31

    CAS:
    <p>AChE-IN-31 (compound 1), a non-competitive acetylcholinesterase (AChE) inhibitor, exhibits potential for Alzheimer's disease research [1].</p>
    Fórmula:C27H44Na2O9S2
    Forma y color:Solid
    Peso molecular:622.74
  • Muscarine tosylate

    CAS:
    <p>Muscarine ((+)-Muscarine) tosylate, a prototype mAChR agonist, serves as a parasympathetic nervous system stimulant and is recognized for its toxic properties [1] [2].</p>
    Fórmula:C16H27NO5S
    Forma y color:Solid
    Peso molecular:345.45
  • Physostigmine hemisulfate

    CAS:
    <p>cholinesterase inhibitor</p>
    Fórmula:C15H21N302H204S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:324.39
  • UNC9994 hydrochloride

    CAS:
    <p>UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.</p>
    Fórmula:C21H23Cl3N2OS
    Forma y color:Solid
    Peso molecular:457.84
  • NAD 299 hydrochloride

    CAS:
    <p>Selective, high affinity 5-HT1A receptor antagonist</p>
    Fórmula:C18H24ClFN2O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:354.85
  • PTAC oxalate

    CAS:
    <p>muscarinic receptor ligand</p>
    Fórmula:C14H21N3O4S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:359.46
  • AAK1-IN-4

    CAS:
    <p>AAK1-IN-4 selectively inhibits AAK1 with IC50 of 4.6 nM; penetrates CNS, oral bioactive, potential for studying neuropathic pain.</p>
    Fórmula:C20H28N4O3
    Forma y color:Solid
    Peso molecular:372.46
  • β-Secretase Inhibitor IV

    CAS:
    <p>β-Secretase Inhibitor IV is a potent, cell-active inhibitor of BACE-1(IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively).</p>
    Fórmula:C31H38N4O5S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:578.72
  • AAK1-IN-5

    CAS:
    <p>AAK1-IN-5: Potent, selective AAK1 inhibitor; CNS-penetrant; oral; IC50: 1.2 nM; Ki: 0.05 nM; cell IC50: 0.5 nM. Useful in neuropathic pain research.</p>
    Fórmula:C19H23F4N3O
    Forma y color:Solid
    Peso molecular:385.4
  • DU-125530

    CAS:
    <p>DU-125530 is a 5-HT1A receptor antagonist.</p>
    Fórmula:C23H26ClN3O5S
    Forma y color:Solid
    Peso molecular:491.99
  • Yhhu-3792 hydrochloride

    CAS:
    <p>Yhhu-3792 hydrochloride is a compound that bolsters the self-renewal capacity of neural stem cells (NSCs), catalyzes the Notch signaling pathway, and upregulates expression of Hes3 and Hes5. It augments the NSC pool, stimulates endogenous neurogenesis in the mouse hippocampal dentate gyrus (DG), and enhances mice's spatial and episodic memory skills. This compound shows promise for researching learning and memory impairments linked to DG dysfunction [1].</p>
    Fórmula:C24H25ClN4O2
    Forma y color:Solid
    Peso molecular:436.93
  • Wf-516

    CAS:
    <p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>
    Fórmula:C25H25Cl2N3O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:502.39
  • Quinolactacin A1

    CAS:
    <p>Quinolactacin A1, a strong AChE inhibitor from Penicillium citrinum, aids Alzheimer's research.</p>
    Fórmula:C16H18N2O2
    Forma y color:Solid
    Peso molecular:270.33
  • 3-Bromocytisine

    CAS:
    <p>3-Bromocytisine ((-)-3-Bromocytisine) is an effective agonist of nAChR (IC50s: 0.28, 0.30 and 31.6 nM for hα4β4, hα4β2, and hα7).</p>
    Fórmula:C11H13BrN2O
    Pureza:99.974%
    Forma y color:Solid
    Peso molecular:269.14
  • PZ-II-029

    CAS:
    <p>PZ-II-029 is a modulator of α6β3γ2-selective GABAA channel.</p>
    Fórmula:C18H15N3O3
    Pureza:99.79%
    Forma y color:Solid
    Peso molecular:321.33
  • (1α,1'S,4β)-Lanabecestat

    CAS:
    <p>(1α,1'S,4β)-Lanabecestat is a Beta site APP Cleaving Enzymel (BACE1) inhibitor, and has IC50s of 2.2 nM (TR-FRET assay) and 0.28 nM (sAPPp release assay),</p>
    Fórmula:C26H28N4O
    Forma y color:Solid
    Peso molecular:412.53
  • ASS234

    CAS:
    <p>ASS234 is a multi-target propylamine used in the treatment of Alzheimer's disease.</p>
    Fórmula:C29H37N3O
    Forma y color:Solid
    Peso molecular:443.62
  • MTPG

    CAS:
    <p>Group II/group III metabotropic glutamate receptor antagonist</p>
    Fórmula:C10H11N5O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:233.23
  • U 89843A

    CAS:
    <p>U 89843A is a positive allosteric modulator of gamma-aminobutyric acid (GABA)A receptors.</p>
    Fórmula:C16H23N5
    Pureza:99.62%
    Forma y color:Solid
    Peso molecular:285.39
  • (+)-Bicuculline methiodide

    CAS:
    <p>(+)-Bicuculline methiodide is a GABAA receptor blocker that blocks epileptogens and may be used in the study of neurological disorders.</p>
    Fórmula:C21H20INO6
    Pureza:99.24%
    Forma y color:Solid
    Peso molecular:509.29
  • YM348

    CAS:
    <p>YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).</p>
    Fórmula:C14H17N3O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:243.3
  • CGP 64213

    CAS:
    <p>CGP 64213 is a GABAb receptor agonist.</p>
    Fórmula:C26H36IN2O7P
    Pureza:98%
    Forma y color:Solid
    Peso molecular:646.45
  • Flesinoxan

    CAS:
    <p>Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).</p>
    Fórmula:C22H26FN3O4
    Forma y color:Solid
    Peso molecular:415.46
  • Frovatriptan

    CAS:
    <p>Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.</p>
    Fórmula:C14H17N3O
    Forma y color:Solid
    Peso molecular:243.3
  • LY 53857

    CAS:
    <p>LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.</p>
    Fórmula:C27H36N2O7
    Forma y color:Solid
    Peso molecular:500.592
  • AChE-IN-44

    CAS:
    <p>AChE-IN-44 (Compound Tap4), an AChE inhibitor, is convertible into its thiazole salt form known as Tat2 [1].</p>
    Fórmula:C31H38ClN3OS2
    Forma y color:Solid
    Peso molecular:568.24
  • Afizagabar

    CAS:
    <p>Afizagabar, a first-in-class α5-GABAAR antagonist, IC50: 585 nM, Ki: 66 nM, may boost memory.</p>
    Fórmula:C19H12FN3O2S
    Forma y color:Solid
    Peso molecular:365.38
  • mGAT-IN-1

    CAS:
    <p>mGAT-IN-1 is a potent, non-selective GAT inhibitor that inhibits mGAT3 activity well (IC50: 2.5 μM, pIC50: 5.61).</p>
    Fórmula:C28H34ClN3O2S2
    Forma y color:Solid
    Peso molecular:544.17
  • cis-PDA

    CAS:
    <p>cis-PDA (cis PDA) is a general ionotropic receptor antagonist. cis-PDA acts by blocking NMDA, AMPA, and kainate-mediated responses.</p>
    Fórmula:C7H11NO4
    Pureza:98.71%
    Forma y color:White Solid
    Peso molecular:173.17
  • JNJ-46281222

    CAS:
    <p>JNJ-46281222: mGlu2-selective, potent PAM, Kd = 1.7 nM, pEC50 = 7.71.</p>
    Fórmula:C23H25F3N4
    Forma y color:Solid
    Peso molecular:414.47
  • AChE-IN-30

    CAS:
    <p>AChE-IN-30 is an acetylcholinesterase (AChE) inhibitor exhibiting neuroprotective effects with an inhibitory concentration (IC 50) of 4.4 μM.</p>
    Fórmula:C22H24N4O2
    Forma y color:Solid
    Peso molecular:376.45
  • AAK1-IN-2

    CAS:
    <p>AAK1-IN-2, a potent (IC50=5.8 nM) AAK1 inhibitor, selective &amp; brain-penetrant, is used for neuropathic pain studies.</p>
    Fórmula:C20H20N4
    Forma y color:Solid
    Peso molecular:316.4
  • 5-HT3 antagonist 1

    CAS:
    <p>5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.</p>
    Fórmula:C22H27N5O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:377.48
  • Pomaglumetad methionil hydrochloride

    CAS:
    <p>LY2140023 hydrochloride: oral methionine prodrug of LY404039, a selective mGlu2/3 agonist, studied for schizophrenia.</p>
    Fórmula:C12H19ClN2O7S2
    Pureza:98.57%
    Forma y color:Solid
    Peso molecular:402.87
  • Diproqualone

    CAS:
    <p>Diproqualone, analogous to methaqualone, exhibits sedative, anxiolytic, anti-inflammatory, and analgesic properties [1].</p>
    Fórmula:C12H14N2O3
    Forma y color:Solid
    Peso molecular:234.255
  • C3

    CAS:
    <p>C3 functions as a selective inhibitor of monoamine oxidase B (MAO-B; IC50= 0.021 µM), demonstrating preference over monoamine oxidase A (MAO-A; IC50= 26.8 µM). This compound, at dosages of 0.1, 1, and 3 mg/kg, effectively counters MPTP-induced reductions in dopamine levels within the mouse brain.</p>
    Fórmula:C18H19FN2O2
    Forma y color:Solid
    Peso molecular:314.35
  • Mesembrine

    CAS:
    <p>Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).</p>
    Fórmula:C17H23NO3
    Forma y color:Solid
    Peso molecular:289.37