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Neurociencia

Neurociencia

Los inhibidores en neurociencia son compuestos diseñados para modular la actividad de proteínas, enzimas o receptores específicos dentro del sistema nervioso. Estos inhibidores son cruciales para estudiar los mecanismos moleculares subyacentes a la función neuronal, la transmisión sináptica y las enfermedades neurodegenerativas. Al dirigirse a los receptores de neurotransmisores, canales iónicos y vías de señalización, los inhibidores en neurociencia ayudan en la exploración de la función cerebral y en el desarrollo de estrategias terapéuticas para trastornos neurológicos como el Alzheimer, Parkinson y la epilepsia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de neurociencia de alta calidad para apoyar su investigación en neurobiología, neurofarmacología y ciencias cognitivas.

Subcategorías de "Neurociencia"

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Se han encontrado 5398 productos de "Neurociencia"

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  • Logo de CymitQuimica
    Targetmol
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    AChE-IN-8

    <p>AChE-IN-8 (Compound 19), potent acetylcholinesterase blocker; IC50 = 1.95 μM; potential Alzheimer's treatment.</p>
    Fórmula:C20H22N4O2S
    Forma y color:Solid
    Peso molecular:382.48

    Ref: TM-T61648

  • PF470
    Targetmol
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    PF470

    CAS:
    <p>PF470 (PF-06297470) is a negative allosteric modulator of the metabotropic glutamate receptor 5 (mGluR5), which demonstrated significant therapeutic effects in Parkinson's disease models. However, its clinical development was halted due to potential issues identified in toxicological studies.</p>
    Fórmula:C18H16N6O
    Forma y color:Solid
    Peso molecular:332.36

    Ref: TM-T200534

  • RTIOXA-43
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    RTIOXA-43

    CAS:
    <p>RTIOXA-43 is an OX2R/OX1R (orexin receptor) dual agonist that increases wakefulnesand is commonly used in studies related to narcolepsy and neural signaling.</p>
    Fórmula:C37H37N5O5S
    Pureza:99.17%
    Forma y color:Solid
    Peso molecular:663.79

    Ref: TM-T87345

  • Notch inhibitor 1
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    Notch inhibitor 1

    CAS:
    <p>Notch inhibitor 1 blocks Notch 1/3 (IC50: 7.8/8.5 nM) and aids cancer research.</p>
    Fórmula:C26H25F7N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:574.49

    Ref: TM-T16341

  • Logo de CymitQuimica
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    Monoamine Oxidase B inhibitor 2

    <p>MAO-B inhibitor 2: potent, reversible, oral, selective (IC50=1.33 nM), BBB-penetrant, with anti-oxidant and anti-inflammatory effects for Parkinson's study.</p>
    Fórmula:C19H19FO3
    Forma y color:Solid
    Peso molecular:314.35

    Ref: TM-T60806

  • Logo de CymitQuimica
    Targetmol
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    LRRK2-IN-6

    <p>LRRK2-IN-6 is an oral, selective LRRK2 inhibitor crossing the blood-brain barrier, targeting GS (IC50: 4.6μM) and WT LRRK2 (IC50: 49μM).</p>
    Fórmula:C23H24F2N4O2S
    Forma y color:Solid
    Peso molecular:458.52

    Ref: TM-T62871

  • (E)-CHBO4
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    (E)-CHBO4

    CAS:
    <p>(E)-CHBO4 is an MAO-B inhibitor with an IC50 value of 0.023 μM, making it a potential candidate for research into Parkinson's disease treatment.</p>
    Fórmula:C15H10BrFO
    Forma y color:Solid
    Peso molecular:305.142

    Ref: TM-T204977

  • Logo de CymitQuimica
    Targetmol
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    K203

    <p>K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.</p>
    Fórmula:C16H18Br2N4O2
    Forma y color:Solid
    Peso molecular:458.15

    Ref: TM-T62857

  • Glutaminyl Cyclase Inhibitor 3
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    Glutaminyl Cyclase Inhibitor 3

    CAS:
    <p>Designed anti-Alzheimer’s compound; potent Glutaminyl Cyclase inhibitor; IC50 at 4.5 nM; reduces brain Aβ; improves cognition.</p>
    Fórmula:C24H32N6O2S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:468.61

    Ref: TM-T11422

  • Logo de CymitQuimica
    Targetmol
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    Dual AChE-MAO B-IN-1

    <p>Dual AChE-MAO B-IN-1: orally active CNS-permeable, safe, stable neuroprotective agent; AChE IC50=550 nM, MAO-B IC50=8.2 nM.</p>
    Fórmula:C23H25F2NO4
    Forma y color:Solid
    Peso molecular:417.45

    Ref: TM-T62172

  • YNT-3708
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    YNT-3708

    CAS:
    <p>YNT-3708 is an orexin receptor (OXR) agonist, exhibiting EC50 values of 14.6 nM for OX1R and 277 nM for OX2R.</p>
    Fórmula:C35H36N4O6S
    Forma y color:Solid
    Peso molecular:640.749

    Ref: TM-T206764

  • Fletazepam
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    Fletazepam

    CAS:
    <p>Fletazepam, a benzodiazepine derivative, exhibits sedative, anti-anxiety, and muscle-relaxant properties. It is utilized in neurological research.</p>
    Fórmula:C17H13ClF4N2
    Forma y color:Solid
    Peso molecular:356.74

    Ref: TM-T201147

  • SEP-363856 mesylate
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    SEP-363856 mesylate

    CAS:
    <p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>
    Fórmula:C10H17NO4S2
    Forma y color:Solid
    Peso molecular:279.38

    Ref: TM-T201258

  • ChEs/MAOs-IN-2
    Targetmol
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    ChEs/MAOs-IN-2

    CAS:
    <p>ChEs/MAOs-IN-2 (compound a11) serves as an inhibitor for both cholinesterases and monoamine oxidases, exhibiting IC 50 values of 0.10 µM for MAO-A, 0.20 µM for MAO-B, 0.30 µM for AChE, and 0.40 µM for BChE. This compound shows promise for Alzheimer's disease research [1].</p>
    Fórmula:C15H12N2O3S
    Forma y color:Solid
    Peso molecular:300.33

    Ref: TM-T86047

  • SNRI-IN-1
    Targetmol
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    SNRI-IN-1

    CAS:
    <p>SNRI-IN-1 (Compound 7a) acts as a dual inhibitor of serotonin and noradrenaline monoamine reuptake, with a P-glycoprotein Efflux Ratio of 20 [1].</p>
    Fórmula:C16H20Cl2N2O2
    Forma y color:Solid
    Peso molecular:343.25

    Ref: TM-T87412

  • Befiradol hydrochloride
    Targetmol
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    Befiradol hydrochloride

    CAS:
    <p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>
    Fórmula:C20H23Cl2F2N3O
    Pureza:99.1%
    Forma y color:Solid
    Peso molecular:430.32

    Ref: TM-T62385

  • LY 215840
    Targetmol
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    LY 215840

    CAS:
    <p>5-HT2/5-HT7 receptor antagonist</p>
    Fórmula:C24H33N3O2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:395.54

    Ref: TM-T22940

  • MAO-A inhibitor 1
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    MAO-A inhibitor 1

    CAS:
    <p>MAO-A Inhibitor 1 (compound VIII) acts as a MAO-A inhibitor and exhibits an IC50 value of 100 μM [1].</p>
    Fórmula:C14H12O4
    Forma y color:Solid
    Peso molecular:244.24

    Ref: TM-T86857

  • PF-06751979
    Targetmol
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    PF-06751979

    CAS:
    <p>PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).</p>
    Fórmula:C18H19F2N5O3S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:455.5

    Ref: TM-T12429

  • HW161023
    Targetmol
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    HW161023

    CAS:
    <p>HW161023 (compound) is an orally active inhibitor of AP2 associated protein kinase 1 (AAK1), exhibiting IC50 values of 5.4 nM for AAK1 and 11.9 μM for hERG. HW161023 can suppress pain response in a rat model of chronic sciatic nerve compression injury.</p>
    Fórmula:C20H24F2N4O
    Forma y color:Solid
    Peso molecular:374.428

    Ref: TM-T206896