Receptor 5-HT
Los receptores 5-HT, también conocidos como receptores de serotonina, son un grupo de receptores acoplados a proteínas G (GPCR) que median los efectos de la serotonina, un neurotransmisor involucrado en la regulación del estado de ánimo, la ansiedad, el sueño, el apetito y otros procesos fisiológicos. Estos receptores se dividen en varios subtipos, cada uno con funciones y propiedades farmacológicas distintas. Los moduladores de los receptores 5-HT se estudian ampliamente por su papel en el tratamiento de la depresión, los trastornos de ansiedad y otras afecciones neuropsiquiátricas. En CymitQuimica, ofrecemos una gama de moduladores de receptores 5-HT de alta calidad para apoyar su investigación en neurofarmacología, trastornos del estado de ánimo y señalización GPCR.
Se han encontrado 988 productos de "Receptor 5-HT"
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LY266097 hydrochloride
CAS:<p>LY266097 hydrochloride is a 5-HT2 antagonist with pKi of 7.7/9.8/7.6 for 5-HT2A/B/C, used in depression research.</p>Fórmula:C21H24Cl2N2O2Pureza:98.58%Forma y color:SolidPeso molecular:407.33Teniloxazine
CAS:Teniloxazine is an orally available antidepressant compound with anti-hypoxic properties.Fórmula:C16H19NO2SPureza:99.29%Forma y color:SolidPeso molecular:289.39Goxalapladib
CAS:Goxalapladib（GSK 677116） is a small molecule compound that can be used to treat cardiovascular risks associated with atherosclerosis.Fórmula:C40H39F5N4O3Pureza:99.64% - 99.93%Forma y color:SolidPeso molecular:718.75Tedatioxetine
CAS:Tedatioxetine (Lu AA24530) is a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) with antidepressant properties.Fórmula:C18H21NSPureza:99.76% - >99.99%Forma y color:SolidPeso molecular:283.43GR 46611
CAS:GR 46611 is a selective 5-HT1B and 5-HT1D receptor agonist and can be used in studies about the treatment of epilepsy.Fórmula:C23H27N3O2Pureza:99.75%Forma y color:SolidPeso molecular:377.48Cianopramine
CAS:Cianopramine (Ro 112465) is a selective 5-hydroxytryptamine uptake inhibitor and a tricyclic antidepressant used in the study of neurological disorders.Fórmula:C20H23N3Pureza:99.92% - 99.92%Forma y color:SolidPeso molecular:305.42BL-1020 Mesylate
CAS:BL-1020 Mesylate (CYP-1020 Mesylate) is a GABA A receptor agonist and D2 antagonist used in studies of neurodegeneration.Fórmula:C28H45ClN4O11S4Pureza:>99.99%Forma y color:SolidPeso molecular:777.39Faxeladol
CAS:Faxeladol: adrenergic, serotonin inhibitor & opioid agonist for neurological studies.Fórmula:C15H23NOPureza:98.77% - 99.67%Forma y color:SolidPeso molecular:233.35Felcisetrag
CAS:<p>Felcisetrag (TD-8954), an oral 5-HT4 agonist with GI prokinetic effects, has a high affinity (pKi 9.4) for h5-HT4(c) receptors.</p>Fórmula:C25H37N5O3Pureza:99.99%Forma y color:SolidPeso molecular:455.598-OH-Dpat
CAS:<p>8-OH-Dpat (8-Hydroxy-DPAT) is a serotonin 1A-receptor agonist that is used experimentally to test the effects of serotonin.</p>Fórmula:C16H25NOPureza:98%Forma y color:SolidPeso molecular:247.38SB 699551 dihydrochloride
CAS:SB 699551 dihydrochloride is a 5-ht5a receptor antagonist.Fórmula:C34H47Cl2N3OPureza:99.83%Forma y color:SolidPeso molecular:584.66Viloxazine
CAS:<p>Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity</p>Fórmula:C13H19NO3Pureza:99.67%Forma y color:SolidPeso molecular:237.29CP 96021
CAS:<p>"CP 96021 is an antagonist of 5-HT1/2 receptors, with anti-inflammatory and anti-ulcer effects for treating GI tract and asthma."</p>Fórmula:C29H21FN4OSPureza:97.81% - 99.62%Forma y color:SoildPeso molecular:492.57(Z)-Thiothixene
CAS:<p>(Z)-Thiothixene (Thiothixene) is an antagonist of serotonergic receptor.</p>Fórmula:C23H29N3O2S2Pureza:99.21%Forma y color:Yellow To Yellow With A Tan Cast PowderPeso molecular:443.63Cilansetron
CAS:Cilansetron is an effective and selective 5-HT3 receptor antagonist that can be used for related diseases caused by colitis.Fórmula:C20H21N3OPureza:99.82% - 99.98%Forma y color:SolidPeso molecular:319.4E6801
CAS:<p>E6801: selective 5-HT6 agonist for research in dementia, Parkinson's, depression, obesity, epilepsy, anxiety, etc.</p>Fórmula:C17H18ClN5O2S2Pureza:96.32% - 99.53%Forma y color:SolidPeso molecular:423.94MM 77 dihydrochloride
CAS:<p>MM 77 dihydrochloride is an effecitve 5-HT1A receptor postsynaptic antagonist with anxiolytic-like activity.</p>Fórmula:C19H29Cl2N3O3Pureza:99.91%Forma y color:SolidPeso molecular:418.36SB-215505
CAS:SB215505: potent 5-HT2B/2C blocker, enhances rat wakefulness/motor activity. (pKi: 5-HT2B - 8.3, 5-HT2C - 7.66, 5-HT2A - 6.77).Fórmula:C19H16ClN3OPureza:98.33%Forma y color:SolidPeso molecular:337.85-HT2 antagonist 1
CAS:<p>5-HT2 antagonist 1 is a potent 5-HT2 receptor antagonist, has weak α1 adrenoceptor blocking activity.</p>Fórmula:C22H29FN4O2Pureza:99.76%Forma y color:SolidPeso molecular:400.49Landipirdine
CAS:<p>Landipirdine (RO-5025181) is a selective 5-HT6R antagonist for the study of central nervous system disorders such as dementia.</p>Fórmula:C18H19FN2O3SPureza:97.61% - 99.37%Forma y color:SolidPeso molecular:362.42Adoprazine
CAS:<p>Adoprazine (SLV313) is a potential atypical antipsychotic bearing potent D2 receptor antagonist and 5-HT1A receptor agonist properties.</p>Fórmula:C24H24FN3O2Pureza:99.83%Forma y color:SolidPeso molecular:405.46SB228357
CAS:<p>SB228357 is a potent and selective antagonist of the 5-HT receptor with pKis of 6.9, 8.0, and 9.0 for 5-HT2A, 5-HT2B, and 5-HT2C, respectively.</p>Fórmula:C22H17F4N3O2Pureza:99.82%Forma y color:SolidPeso molecular:431.38Ticalopride
CAS:Ticalopride: 5-HT3 agonist for digestive, orofacial, ENT disorders, and bulimia, GERD, IBS research.Fórmula:C14H20ClN3O3Pureza:99.51%Forma y color:SolidPeso molecular:313.785HT6-ligand-1
CAS:<p>5HT6-ligand-1 is an orally active ligand of 5-HT6 receptor (Ki = 1.43 nM).</p>Fórmula:C20H22BrN3O2SPureza:99.24% - 99.93%Forma y color:SolidPeso molecular:448.38RS 42358-197
CAS:<p>RS 42358-197 (RS 25259-007) is a competitive 5-HT3 receptor antagonist.</p>Fórmula:C19H23ClN2OPureza:99.70%Forma y color:SolidPeso molecular:330.85SPD-473 citrate
CAS:<p>SPD-473 citrate is an inhibitior of serotonin/dopamine/norepinephrine reuptake.</p>Fórmula:C23H31Cl2NO8SPureza:99.37%Forma y color:SolidPeso molecular:552.47Itasetron
CAS:<p>Itasetron, a 5-HT3 antagonist, prevents memory loss in rats and has antiemetic effects in cancer treatments.</p>Fórmula:C16H20N4O2Pureza:98.58% - 99.33%Forma y color:SolidPeso molecular:300.36Roxindole
CAS:Roxindole: dopamine agonist, serotonin reuptake inhibitor, 5-HT1A agonist, developed for schizophrenia.Fórmula:C23H26N2OPureza:98.03% - 98.93%Forma y color:SolidPeso molecular:346.47Aplindore Fumarate
CAS:Aplindore Fumarate (DAB-452), a selective dopamine D2/D3 partial agonist, is used in Parkinson's and schizophrenia research.Fórmula:C22H22N2O7Pureza:99.66%Forma y color:SolidPeso molecular:426.42Nexopamil
CAS:<p>Nexopamil (LU-49938) is a dual calcium channel and 5-HT2A receptor antagonist that inhibits cell contraction and growth.</p>Fórmula:C24H40N2O3Pureza:97.87% - >99.99%Forma y color:SolidPeso molecular:404.59ATC 0175 hydrochloride
CAS:<p>ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective.</p>Fórmula:C23H26ClF2N5OPureza:99.98%Forma y color:SolidPeso molecular:461.93Perphenazine dihydrochloride
CAS:Perphenazine dihydrochloride: Oral dopamine, histamine-1 antagonist; targets D2, D3, 5-HT2A, Alpha-1A; may treat psychiatric disorders, cancer.Fórmula:C21H28Cl3N3OSPureza:99.67%Forma y color:SolidPeso molecular:476.89Liafensine
CAS:Liafensine(BMS-820836): Selective inhibitor for serotonin, norepinephrine, dopamine reuptake; targets major depression, CNS disorders.Fórmula:C24H22N4Pureza:99.91%Forma y color:SolidPeso molecular:366.46Piromelatine
CAS:Piromelatine is an agonist of melatonin MT1/MT2 receptors, 5-HT1A and 5-HT1D, and an antagonist of 5-HT2B.Piromelatine has antinociceptive activity withFórmula:C17H16N2O4Pureza:99.83%Forma y color:SolidPeso molecular:312.32Masupirdine free base
CAS:Masupirdine free base (SUVN-502 free base) is a 5-HT6 receptor antagonist that can be used to study neurological disorders like Alzheimer's disease.Fórmula:C21H24BrN3O3SPureza:98.36% - 99.65%Forma y color:SolidPeso molecular:478.4RS 67333 hydrochloride
CAS:RS 67333 hydrochloride is a selective 5-HT4R partial agonist (pKi=8.7) with neuroprotective properties for Alzheimer's research.Fórmula:C19H30Cl2N2O2Pureza:98.78%Forma y color:SolidPeso molecular:389.36Litoxetine
CAS:Litoxetine: a selective 5-HT inhibitor & 5-HT3 antagonist, used as an antidepressant with antiemetic effects, Ki=85 nM.Fórmula:C16H19NOPureza:99.68%Forma y color:SolidPeso molecular:241.33Lensiprazine
CAS:Lensiprazine (SLV314) is a potent dopamine D(2) receptor antagonist that acts as a serotonin reuptake inhibitor , and can be used to study bipolar disorder andFórmula:C24H27FN4O2Pureza:97.86%Forma y color:SolidPeso molecular:422.5H-9 dihydrochloride
CAS:<p>H-9 dihydrochloride: Strong PKA inhibitor, curbs 5-HT response and EGF signaling, affects pharyngeal function.</p>Fórmula:C11H15Cl2N3O2SPureza:97.3%Forma y color:SolidPeso molecular:324.235-HT6/7 antagonist 1
CAS:<p>5-HT6/7 antagonist 1 is a dual 5-HT6/7/2A and D2 receptor antagonist for the study of dementia and Alzheimer's disease.</p>Fórmula:C22H20FN3O3Pureza:98.78% - 99.26%Forma y color:SolidPeso molecular:393.41BMY-14802 hydrochloride
CAS:BMY-14802 hydrochloride (BMS 181100 hydrochloride) is a selective antagonist of σ receptor (IC50 = 112 nM) with antipsychotic effects.Fórmula:C18H23ClF2N4OPureza:99.97%Forma y color:SolidPeso molecular:384.85Tiospirone
CAS:Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and a dopamine blocker used in the study of neurological disorders such as schizophrenia.Fórmula:C24H32N4O2SPureza:99.74%Forma y color:SolidPeso molecular:440.65-HT1A modulator 1
CAS:<p>5-HT1A modulator 1 displays very high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).</p>Fórmula:C21H25N3O2SPureza:99.68%Forma y color:SolidPeso molecular:383.51Pimethixene maleate
CAS:<p>Pimethixene maleate (Pimetixene maleate) is a 5-HT2B receptor antagonist with sedative activity that can be used to study dry cough in children.</p>Fórmula:C23H23NO4SPureza:99.55%Forma y color:SolidPeso molecular:409.5Ecopipam
CAS:<p>Ecopipam: orally active, selective dopamine D1/D5 antagonist (Ki: 1.2 nM/2.0 nM). 40x more selective over D2/D4/5-HT/α2a. For schizophrenia, obesity research.</p>Fórmula:C19H20ClNOPureza:99.68%Forma y color:SolidPeso molecular:313.82Anpirtoline hydrochloride
CAS:<p>Anpirtoline hydrochloride (D-16949 hydrochloride) is a 5-HT1B receptor agonist and 5-HT3 receptor antagonist used in the study of dyskinesia.</p>Fórmula:C10H14Cl2N2SPureza:>99.99% - >99.99%Forma y color:SolidPeso molecular:265.20Lecozotan HCl
CAS:<p>Lecozotan HCl is a selective 5-HT antagonist boosting glutamate and acetylcholine release without causing 5-HT(1A) tolerance.</p>Fórmula:C28H30ClN5O3Pureza:99.04%Forma y color:SolidPeso molecular:520.02Cyamemazine
CAS:Cyamemazine is an antipsychotic compound with sedative and anxiolytic activity.Cyamemazine is a 5-HT3, 5-HT2A, and 5-HT2C receptor antagonist.Fórmula:C19H21N3SPureza:97.01%Forma y color:SolidPeso molecular:323.46Ricasetron
CAS:Ricasetron (Brl 46470) is a 5-HT3 receptor antagonist with pro-axonal lysing properties and is used in the study of anxiety disorders and anxiety disorders.Fórmula:C19H27N3OPureza:99.52%Forma y color:SolidPeso molecular:313.44Femoxetine hydrochloride
CAS:<p>Femoxetine hydrochloride is a selective 5-hydroxytryptamine reuptake inhibitor used in the study of migraine, depression and eating disorders.</p>Fórmula:C20H26ClNO2Pureza:99.63%Forma y color:SolidPeso molecular:347.88Rilapine
CAS:<p>Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can be used to study neurological disorders.</p>Fórmula:C22H20ClN3Pureza:97.76% - 99.20%Forma y color:SolidPeso molecular:361.87Sarizotan HCl
CAS:Sarizotan HCl (EMD 128130 HCl) is a 5-HT1A receptor and dopamine receptor agonist and an hERG channel inhibitor used in Parkinson;s disease research.Fórmula:C22H22ClFN2OPureza:96%Forma y color:SolidPeso molecular:384.87DA-6886
CAS:<p>DA-6886 is a 5-HT4 agonist, relaxes rat oesophagus, with 1000x selectivity over hERG channels, pIC50: 4.3.</p>Fórmula:C19H28Cl2N6O2Pureza:99.28% - 99.91%Forma y color:SolidPeso molecular:443.37PNU-282987 free base
CAS:<p>PNU-282987 is an α7 nAChR agonist (EC50=154 nM) and a 5-HT3 antagonist (IC50=4541 nM) for nervous system research.</p>Fórmula:C14H17ClN2OPureza:99.64%Forma y color:SolidPeso molecular:264.75LY-2624803
CAS:LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep.Fórmula:C22H25N3O3Pureza:99.78% - 99.97%Forma y color:SolidPeso molecular:379.455-HT2 agonist-1
CAS:<p>Compound 24, a 5-HT2 agonist-1, selectively activates 5-HT2A, 5-HT2B, and 5-HT2C receptors with IC50 values of 10 nM, 8.3 nM, and 1.6 nM, respectively.</p>Fórmula:C19H23ClN2O2Pureza:98%Forma y color:SolidPeso molecular:346.85Befiradol
CAS:Befiradol (NLX-112) is an agonist of 5-HT1A receptor.Fórmula:C20H22ClF2N3OForma y color:SolidPeso molecular:393.86Dothiepin
CAS:<p>Dothiepin (Dosulepin; Dothep), an antidepressant with sedative/anxiolytic properties, preferentially inhibits noradrenaline over serotonin uptake, enhancing</p>Fórmula:C19H21NSPureza:98%Forma y color:SolidPeso molecular:295.44(S)-Renzapride
<p>(S)-Renzapride (BRL 24924), 5-HT4 agonist (Ki 115 nM), 5HT2b/5HT3 antagonist, for C-IBS study.</p>Fórmula:C16H22ClN3O2Forma y color:SolidPeso molecular:323.82Gentisein
CAS:<p>Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7</p>Fórmula:C13H8O5Pureza:96.89%Forma y color:SolidPeso molecular:244.2Flesinoxan
CAS:Flesinoxan is a hypotensive agent and is an effective, high affinity, and selective 5-hydroxytryptamine1A receptor agonist (EC50: 24 nM).Fórmula:C22H26FN3O4Forma y color:SolidPeso molecular:415.465-HT2A antagonist 1
CAS:<p>5-HT2A antagonist 1, from US5728835A & JP 1007727, may treat gastrointestinal and circulatory issues.</p>Fórmula:C26H28N4O2Pureza:98%Forma y color:SolidPeso molecular:428.53LY108742
CAS:LY108742 is an antagonist of 5-HT2.Fórmula:C21H28N2O3Pureza:98%Forma y color:SolidPeso molecular:356.46MIN-117
CAS:MIN-117, a SSRI/5-HT receptor antagonist, is potentially used for the treatment of depression.Fórmula:C25H26Cl3N3O4Pureza:98%Forma y color:SolidPeso molecular:538.854-Chloro-L-phenylalanine
CAS:<p>4-Chloro-L-phenalanine (L-PCPA) is an inhibitor of 5-HT biosynthesis and a non-specific antagonist of tryptophan hydroxylases (TPH1 and TPH2).</p>Fórmula:C9H10ClNO2Pureza:99.76% - 99.96%Forma y color:SolidPeso molecular:199.63LY 53857
CAS:LY 53857 is a potent and selective antagonist of 5-HT2 serotonin receptor.Fórmula:C27H36N2O7Forma y color:SolidPeso molecular:500.5925-HT2 agonist-1 free base
CAS:<p>Compound 24 (5-HT2 agonist-1 free base) is a potent agonist for 5-HT2A, 5-HT2B, and 5-HT2C receptors, exhibiting IC50 values of 10 nM, 8.3 nM, and 1.6 nM,</p>Fórmula:C19H22N2O2Pureza:98%Forma y color:SolidPeso molecular:310.39SB 649915
CAS:SB 649915 is a serotonin reuptake inhibitor and 5-HT1A and 5-HT1B receptor antagonist.Fórmula:C26H29N3O3Forma y color:SolidPeso molecular:431.53GR-127935
CAS:GR-127935 is a potent and selective 5-HT1B/1D receptor antagonist.Fórmula:C29H31N5O3Forma y color:SolidPeso molecular:497.59NAS181
CAS:rat 5-HT1B receptor antagonistFórmula:C21H34N2O10S2Pureza:98%Forma y color:SolidPeso molecular:538.63Facinicline hydrochloride
CAS:Facinicline hydrochloride (RG3487) is both a novel nicotinic alpha-7 receptor (alpha7nAChR) partial agonist (Ki = 6 nM) and an antagonist of 5-HT3(Ki = 1.2 nM).Fórmula:C15H19ClN4OPureza:98.70%Forma y color:SolidPeso molecular:306.79Nemonapride
CAS:Nemonapride is a dopamine D2-like receptor antagonist.Fórmula:C21H26ClN3O2Pureza:98%Forma y color:SolidPeso molecular:387.9Indeloxazine hydrochloride
CAS:Indeloxazine HCl: Serotonin releaser, NE reuptake inhibitor, NMDA antagonist; antidepressant that boosts acetylcholine in rats.Fórmula:C14H18ClNO2Pureza:98%Forma y color:SolidPeso molecular:267.75GYKI-46903 HCl
CAS:GYKI-46903 is a noncompetitive 5-HT3 receptor antagonist.Fórmula:C17H21ClFNO2Forma y color:SolidPeso molecular:325.81FPPQ
CAS:FPPQ blocks 5-HT3 and 5-HT6 receptors (Ki: 0.9 & 3 nM) and may improve psychosis and cognition.Fórmula:C21H19FN4O2SForma y color:SolidPeso molecular:410.46Wf-516
CAS:<p>Wf-516 is a 5-HT reuptake inhibitor (Kis: 5 nM and 40 nM for 5-HT1A receptor and 5-HT2A receptor in humans, respectively), and with potent antidepressant</p>Fórmula:C25H25Cl2N3O4Pureza:98%Forma y color:SolidPeso molecular:502.39Robalzotan
CAS:Robalzotan is a selective 5-HT1A receptor antagonist.Fórmula:C18H23FN2O2Pureza:98%Forma y color:SolidPeso molecular:318.39Velusetrag
CAS:Velusetrag(TD-5108), a potent 5-HT4 agonist, is in development for gastroparesis, constipation, and IBS.Fórmula:C25H36N4O5SForma y color:SolidPeso molecular:504.64Mesembrine
CAS:Mesembrine is an alkaloid, a 5-HT transporter inhibitor (K i 1.4 nM), and inhibits PDE4B (IC50 7.8 μM).Fórmula:C17H23NO3Forma y color:SolidPeso molecular:289.37PZ-1190
CAS:<p>PZ-1190, a multitarget ligand for serotonin and dopamine receptors, exhibits potential antipsychotic activity in rodents [1].</p>Fórmula:C27H30N4O2S2Pureza:98%Forma y color:SolidPeso molecular:506.685-HT2C agonist-3
CAS:<p>5-HT2C agonist-3 ((+)-19), a selective 5-HT2C agonist (EC 50: 24 nM, Ki: 78 nM), exhibits antipsychotic-like activity by blocking amphetamine-induced</p>Fórmula:C19H23ClFNO2Pureza:98%Forma y color:SolidPeso molecular:351.84YM348
CAS:YM348 is an effective and orally active 5-HT2C receptor agonist. YM348 also shows a high affinity for the cloned human 5-HT2C receptor (Ki: 0.89 nM).Fórmula:C14H17N3OPureza:98%Forma y color:SolidPeso molecular:243.3(±)-Fabesetron hydrochloride
CAS:<p>FK1052 hydrochloride is a potent 5-HT3 and 5-HT4 receptor dual antagonist.</p>Fórmula:C18H20ClN3OPureza:98%Forma y color:SolidPeso molecular:329.82Capeserod HCl
CAS:<p>Capeserod HCl, a 5-hydroxytriptamine 4 (5-HT4) receptor agonist, is used potentially for the treatment of Alzheimer's disease.</p>Fórmula:C23H26Cl2N4O4Pureza:98%Forma y color:SolidPeso molecular:493.38Butriptyline
CAS:Butriptyline (Butriptylene), a tricyclic antidepressant, is effective when administered orally [1].Fórmula:C21H27NForma y color:SolidPeso molecular:293.45UNC9994
CAS:UNC9994 is a β-arrestin-biased dopamine D₂ receptor agonist (β-arrestin EC50 = 50 nM; Emax = 97%) with robust in vivo antipsychotic drug-like activities.Fórmula:C21H22Cl2N2OSForma y color:SolidPeso molecular:421.38SB 258719
CAS:SB 258719 is a selective antagonist of 5-HT7 receptor with pKi of 7.5.Fórmula:C18H30N2O2SPureza:99.73%Forma y color:SolidPeso molecular:338.515-HT2A receptor agonist-3
CAS:<p>5-HT2A receptor agonist-3 represents the highest selectivity for the human 5-HT2A receptor currently identified, exhibiting a K i of 2.5 nM.</p>Fórmula:C21H26BrNO3Pureza:98%Forma y color:SolidPeso molecular:420.34MDL-74156
CAS:MDL-74156 is an active metabolite of dolasetron and a 5-hydroxy-tryptamine3 (5-HT3) antagonist.Fórmula:C19H22N2O3Forma y color:SolidPeso molecular:326.392-Methyl-5-HT
CAS:<p>2-Methyl-5-HT (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.</p>Fórmula:C11H14N2OPureza:97.18%Forma y color:SolidPeso molecular:190.24FK-1052
CAS:FK-1052 is a serotonin 3 & 4 dual receptor antagonist.Fórmula:C18H19N3OForma y color:SolidPeso molecular:293.361-Carboxycyclohexaneacetic Acid
CAS:1-Carboxycyclohexaneacetic acid may be present as a potential impurity in commercial gabapentin, an antiepileptic drug. Furthermore, it serves as a precursor for synthesizing antagonists targeting the serotonin (5-HT) receptor subtype 5-HT2A.Fórmula:C9H14O4Forma y color:SolidPeso molecular:186.207UNC9994 hydrochloride
CAS:UNC9994 hydrochloride is a selective β-arrestin-biased D2R agonist, Ki of 79 nM, that stimulates β-arrestin and modulates cAMP.Fórmula:C21H23Cl3N2OSForma y color:SolidPeso molecular:457.84DU-125530
CAS:DU-125530 is a 5-HT1A receptor antagonist.Fórmula:C23H26ClN3O5SForma y color:SolidPeso molecular:491.99Cyanopindolol fumarate
CAS:<p>Cyanopindolol fumarate is a 5-HT receptor antagonist [1].</p>Fórmula:C16H21N3O2C4H4O4Forma y color:SolidPeso molecular:345.4Abaperidone
CAS:<p>Abaperidone is an atypical antipsychotic, antagonizes 5-HT2A (IC50=6.2 nM) and D2 receptors (IC50=17 nM), reduces hsp70 mRNA in rat brains.</p>Fórmula:C25H25FN2O5Pureza:98.22%Forma y color:SolidPeso molecular:452.47R-96544
CAS:<p>R-96544 is an orally active antagonist of the 5-HT2A receptor that has demonstrated the ability to inhibit platelet aggregation in vitro [1].</p>Fórmula:C22H30ClNO3Forma y color:SolidPeso molecular:391.93Brilaroxazine
CAS:<p>Brilaroxazine (RP5063): multimodal dopamine/5-HT modulator, partial agonist at D2/D3/D4, 5-HT1A/2A, and antagonist at 5-HT2B/7.</p>Fórmula:C22H25Cl2N3O3Pureza:99.36%Forma y color:SolidPeso molecular:450.365-HT3-In-1
CAS:5-HT3-In-1 (compound example 8) exhabits with 5-HT3 inhibition activity.Fórmula:C16H21ClN4O3Pureza:98%Forma y color:SolidPeso molecular:352.825-HT2C agonist-3 free base
CAS:<p>5-HT2C agonist-3 ((+)-19) free base, a selective 5-HT2C agonist (EC50: 24 nM, Ki: 78 nM), exhibits antipsychotic drug-like activity and inhibits Amphetamine-</p>Fórmula:C19H22FNO2Pureza:98%Forma y color:SolidPeso molecular:315.38GR 125487 sulfamate
CAS:GR 125487 sulfamate is a 5-HT4 receptor antagonist.Fórmula:C19H29FN4O8S2Pureza:98%Forma y color:SolidPeso molecular:524.58SDZ-216525
CAS:SDZ-216525, a 5-HT1A receptor antagonist, inhibits the tracheal contractions induced both by NKA (10 nM-3 microM) and 5-HT (10 nM-10 microM) (n=4-10).Fórmula:C25H28N4O5SForma y color:SolidPeso molecular:496.58CP-122288
CAS:<p>CP-122288: potent, selective 5-HT1B/D/F agonist; inhibits plasma protein extravasation, neurogenic inflammation.</p>Fórmula:C16H23N3O2SPureza:98%Forma y color:SolidPeso molecular:321.44GR 127935 hydrochloride
CAS:5-HT1B/1D receptor antagonistFórmula:C29H32ClN5O3Pureza:98%Forma y color:SolidPeso molecular:534.05(S)-Bexicaserin
CAS:<p>(S)-Bexcaserin (compound 2) serves as a 5-HT2C receptor agonist, presenting research possibilities in obesity and psychiatric disorders [1].</p>Fórmula:C15H19F2N3OPureza:98%Forma y color:SolidPeso molecular:295.335-HT3 antagonist 1
CAS:5-HT3 antagonist 1 is a potent and selective antagonist of 5-HT3 receptor.Fórmula:C22H27N5OPureza:98%Forma y color:SolidPeso molecular:377.48LY320954
CAS:<p>LY320954 is an antagonist of 5-HT2A receptor.</p>Fórmula:C21H26N4O3Pureza:98%Forma y color:SolidPeso molecular:382.46LY-426965
CAS:<p>LY-426965 is a selective, potent, orally bioavailable 5-HT1A antagonist.</p>Fórmula:C28H38N2O2Forma y color:SolidPeso molecular:434.615-HT2A&5-HT2C agonist-1
CAS:<p>5-HT2A&5-HT2C agonist-1 (Example 2) is a dual-acting agent targeting the 5-HT2A and 5-HT2C receptors with respective IC50 values of 196 nM and 0.9 nM.</p>Fórmula:C14H20N2OPureza:98%Forma y color:SolidPeso molecular:232.32NAD 299 hydrochloride
CAS:Selective, high affinity 5-HT1A receptor antagonistFórmula:C18H24ClFN2O2Pureza:98%Forma y color:SolidPeso molecular:354.85Osemozotan Free Base
CAS:Osemozotan Free Base is a 5-HT(1A) receptor agonist.Fórmula:C19H21NO5Forma y color:SolidPeso molecular:343.37NAS-181
CAS:NAS-181 is a potent and selective rat 5-hydroxytryptamine 1B (r5-HT1B) antagonist (Ki: 47 nM).NAS-181 enhances the accumulation of 5-HTP in rat brain regions.Fórmula:C20H30N2O7SForma y color:SolidPeso molecular:442.53Frovatriptan
CAS:Frovatriptan, potent 5-HT 1B/D agonist, shows high cerebroselectivity and efficacy for migraine with aura.Fórmula:C14H17N3OForma y color:SolidPeso molecular:243.3L-772,405
CAS:L-772,405 is a highly selective agonists of h5-HT(1D) receptor.Fórmula:C26H31FN6OPureza:98%Forma y color:SolidPeso molecular:462.56PNU109291
CAS:PNU109291, a potent and selective agonist of the 5-HT1D receptor, effectively mitigates dural plasma extravasation induced by trigeminal ganglion stimulation.Fórmula:C24H31N3O3Pureza:98%Forma y color:SolidPeso molecular:409.52Gepirone
CAS:Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs.Fórmula:C19H29N5O2Pureza:99.35% - 99.89%Forma y color:SolidPeso molecular:359.47Osemozotan HCl
CAS:Osemozotan is a 5-HT1A receptor agonist potentially for the treatment of generalized anxiety disorder.Fórmula:C19H22ClNO5Pureza:98.87% - 99.63%Forma y color:SolidPeso molecular:379.84Didesmethyl cariprazine
CAS:<p>Didesmethyl cariprazine, Cariprazine's active metabolite, treats schizophrenia/bipolar with D3/D2 affinity; half-life 1-3 weeks.</p>Fórmula:C19H28Cl2N4OPureza:99.52%Forma y color:SolidPeso molecular:399.36WAY-607695
CAS:<p>WAY-607695 is a potential 5-HT1A receptor agonist.</p>Fórmula:C13H12FNO2Pureza:99.82%Forma y color:SolidPeso molecular:233.24SB 216641 hydrochloride
CAS:SB 216641 hydrochloride (SB-216641A) is a 5-HT1B/D receptor antagonist with anxiolytic properties.Fórmula:C28H31ClN4O4Pureza:98.06% - 99.23%Forma y color:SolidPeso molecular:523.02SB-616234-A
CAS:SB-616234-A is a selective and orally bioavailable antagonist of 5-HT1B receptor, with anxiolytic and antidepressant activity.Fórmula:C32H36ClN5O3Pureza:99.72%Forma y color:SolidPeso molecular:574.11Lumateperone
CAS:<p>Lumateperone (ITI 722) is a 5HT2A receptor antagonist and a dopamine receptor phosphoprotein modulator (DPPM).</p>Fórmula:C24H28FN3OPureza:99.68% - 99.91%Forma y color:SolidPeso molecular:393.5Revexepride
CAS:Revexepride, a 5-HT4 agonist, may boost CYP3A4, used for treating GERD.Fórmula:C21H32ClN3O4Pureza:98%Forma y color:SolidPeso molecular:425.95Elzasonan hydrochloride
CAS:<p>Elzasonan hydrochloride is a serotonin 1B and serotonin 1D receptor antagonist. It is utilized in the study of depression.</p>Fórmula:C22H24Cl3N3OSForma y color:SolidPeso molecular:484.87Tipindole
CAS:Tipindole is a serotonin antagonist utilized in research related to depression.Fórmula:C16H20N2O2SForma y color:SolidPeso molecular:304.41Etoperidone
CAS:Etoperidone is an antidepressant that acts as an orally active reuptake inhibitor for serotonin (serotonin) and noradrenaline (nor-adrenaline). It demonstrates specific binding affinities (Kd) for several receptors: 36 nM at the 5-HT2 receptor, 38 nM at the α1-adrenergic receptor (α1-adrenergic receptor), 85 nM at the 5-HT1A receptor, and 570 nM at the α2-adrenergic receptor (α2-adrenergic receptor).Fórmula:C19H28ClN5OForma y color:SolidPeso molecular:377.91ASP-2205
CAS:<p>ASP-2205, a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM), enhances the urethral closure reflex mediated by the genital nerve, thereby preventing urinary incontinence.</p>Fórmula:C19H28N2OForma y color:SolidPeso molecular:300.44YM-31636 free base
CAS:<p>YM-31636 (free base) is an orally active, potent, and selective agonist of the 5-HT3 receptor with a pKi value of 9.67. This compound induces contraction in isolated guinea pig distal colon and provokes tachycardia in isolated guinea pig right atrium, demonstrating a relative intrinsic activity of about 0.23. YM-31636 (free base) holds potential for research in constipation management.</p>Fórmula:C14H11N3SForma y color:SolidPeso molecular:253.32R-96544 hydrochloride
CAS:5-HT2 receptor antagonistFórmula:C22H29NO3Pureza:98%Forma y color:SolidPeso molecular:355.47Tiprenolol hydrochloride
CAS:Tiprenolol hydrochloride is a β-adrenoceptor (β-adrenoceptor) antagonist. This compound is effective in eliminating ventricular arrhythmias in dogs caused by intravenous administration of adrenaline, following inhalation of halothane.Fórmula:C13H22ClNO2SForma y color:SolidPeso molecular:291.84AAZ-A 154 benzoate
CAS:<p>AAZ-A 154 benzoate is a selective, competitive, and non-hallucinogenic 5-HT2AR antagonist. This compound facilitates neuronal growth in rodents and produces lasting beneficial behavioral effects.</p>Fórmula:C21H26N2O3Forma y color:SolidPeso molecular:354.445-HT2A/5-HT2C inverse agonist 1
CAS:<p>5-HT2A/5-HT2C inverse agonist 1 serves as a dual and potent inverse agonist for the 5-HT2A and 5-HT2C receptors, with hERG inhibition properties that mitigate cardiovascular risks. Demonstrating significant antipsychotic efficacy in the MK-801-induced mouse model, this compound holds potential for psychosis research.</p>Fórmula:C24H35N5O2Forma y color:SolidPeso molecular:425.57Terguride
CAS:Terguride: treats hyperprolactinemia, blocks 5-HT2A/B, activates dopamine receptors, studied for PAH.Fórmula:C20H28N4OForma y color:SolidPeso molecular:340.46Remlifanserin
CAS:Remlifanserin is a potent inverse agonist of the serotonin receptor (5-HT2A).Fórmula:C24H29F2N3O2Forma y color:SolidPeso molecular:429.505-HT6/5-HT2AR antagonist-1
Potent 5-HT6/5-HT2A receptors dual antagonist with K i of 11 nM & 39 nM.Fórmula:C21H26N6SForma y color:SolidPeso molecular:394.54VA012
CAS:<p>VA012 (compound 11) acts as a positive allosteric modulator (PAM) of the serotonin 5-HT2C receptor. It has been shown to reduce food intake and prevent weight gain during subchronic administration without causing central nervous system-related discomfort. VA012 is applicable in obesity research.</p>Fórmula:C21H19N3Forma y color:SolidPeso molecular:313.40F 14679
CAS:<p>F 14679 is a potent 5-HT1A agonist (pKi=10.23) with a maximum Ca2t response similar to 5-HT.</p>Fórmula:C21H25ClF2N4OPureza:99.09%Forma y color:SolidPeso molecular:422.9Sulamserod hydrochloride
CAS:<p>Sulamserod hydrochloride is a 5-HT4 receptor antagonist. It is utilized in research related to gastrointestinal disorders.</p>Fórmula:C19H29Cl2N3O5SForma y color:SolidPeso molecular:482.42AAZ-A 154
CAS:<p>AAZ-A 154 is a selective, competitive, and non-hallucinogenic antagonist of the 5-HT2AR. It promotes neuronal growth in rodents and results in lasting beneficial behavioral effects.</p>Fórmula:C14H20N2OForma y color:SolidPeso molecular:232.32(S)-Praziquantel
CAS:(S)-Praziquantel is the inactive isomer of R-praziquantel.Fórmula:C19H24N2O2Forma y color:SolidPeso molecular:312.406AAZ-A 154 hydrobromide
CAS:AAZ-A 154 hydrobromide is a selective, competitive, non-hallucinogenic 5-HT2AR antagonist. It promotes neuronal growth in rodents and yields enduring beneficial behavioral effects.Fórmula:C14H21BrN2OForma y color:SolidPeso molecular:313.23Rodatristat
CAS:<p>Rodatristat is an effective tryptophan hydroxylase 1 and TPH2 inhibitor (IC50s: 33 nM and 7 nM, respectively).</p>Fórmula:C27H27ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:561.98(-)-5-HT2C agonist-3
CAS:<p>Compound (−)-19, also known as (-)-5-HT2C agonist-3, is a selective 5-HT2C agonist exhibiting a preference for Gq signaling. It demonstrates efficiency with EC50 values for 5-HT2 receptor subtypes as follows: 5-HT2C at 103 nM, 5-HT2B at 570 nM, and 5-HT2A at 72 nM. This compound is utilized in research on antipsychotics.</p>Fórmula:C19H23ClFNO2Forma y color:SolidPeso molecular:351.84LP 12 hydrochloride hydrate
LP 12 hydrochloride hydrate: potent, selective 5-HT7 agonist (Ki: 0.13 nM); less affinity for D2, 5-HT1A/2A receptors.Fórmula:C32H39N3O·HCl·xH2OForma y color:SolidLB-102
CAS:LB-102 is an orally active inhibitor of dopamine D2, D3, and serotonin 5-HT7 receptors, utilized in the study of schizophrenia and other psychiatric disorders.Fórmula:C18H29N3O4SForma y color:SolidPeso molecular:383.51AAZ-A 154 hydrochloride
CAS:<p>AAZ-A 154 hydrochloride is a selective, competitive, non-hallucinogenic antagonist of 5-HT2AR. It promotes neuronal growth in rodents and results in enduring beneficial behavioral effects.</p>Fórmula:C14H21ClN2OForma y color:SolidPeso molecular:268.78DSP-1053 benzenesulfonate
CAS:DSP-1053: Benzylpiperidine-based, potent SERT inhibitor (Ki=1.02nM), partial 5-HT1A receptor agonist (Ki=5.05nM), antidepressant.Fórmula:C32H38BrNO7SForma y color:SolidPeso molecular:660.62LY 215840
CAS:5-HT2/5-HT7 receptor antagonistFórmula:C24H33N3O2Pureza:98%Forma y color:SolidPeso molecular:395.54U92016A hydrochloride
CAS:U92016A hydrochloride: potent, orally active 5-HT1A agonist, metabolically stable, high intrinsic activity, Ki=0.2 nM.Fórmula:C19H26ClN3Forma y color:SolidPeso molecular:331.89Ro4368554
CAS:<p>Ro4368554 is a selective 5-HT6 antagonist capable of crossing the blood-brain barrier. It can reverse memory deficits caused by scopolamine and tryptophan depletion. Ro4368554 is applicable for research related to memory impairments.</p>Fórmula:C19H21N3O2SForma y color:SolidPeso molecular:355.454AChE-IN-5
AChE-IN-5: oral, crosses blood-brain barrier, targets AChE/5-HT1A/SERT, potent with 2.29 nM IC50.Fórmula:C38H45N5OForma y color:SolidPeso molecular:587.85-IAI hydrochloride
CAS:<p>5-IAI hydrochloride is a psychoactive analog of para-iodoamphetamine. 5-IAI hydrochloride significantly reduces serotonin uptake sites and hippocampal serotonin levels in rats.</p>Fórmula:C9H11ClINForma y color:SolidPeso molecular:295.548Befiradol hydrochloride
CAS:<p>Befiradol HCl (NLX-112) is a selective 5-HT1A receptor agonist with anxiolytic effects and prevents ATXN3 aggregation.</p>Fórmula:C20H23Cl2F2N3OPureza:99.1%Forma y color:SolidPeso molecular:430.325-HT7R antagonist 3
CAS:Compound 6.4, also known as 5-HT7R antagonist 3, is a selective antagonist of the 5-HT7R with a Ki of 8 nM. It exhibits significantly less affinity towards D2R, 5-HT1AR, and 5-HT2AR with Ki values of 511 nM, 8930 nM, and 5786 nM, respectively. In mice, 5-HT7R antagonist 3 demonstrates anti-depressant and anti-anxiety activities.Fórmula:C30H33FN4O3Forma y color:SolidPeso molecular:516.61SB 258741 hydrochloride
SB 258741 hydrochloride is a potent antagonist of the 5-HT 7 receptor, designed specifically for studying schizophrenia [1].Fórmula:C19H31ClN2O2SForma y color:SolidPeso molecular:386.98Beloxepin
CAS:Beloxepin is an oral dual selective inhibitor of serotonin and norepinephrine uptake.Fórmula:C19H21NO2Pureza:98%Forma y color:SolidPeso molecular:295.3825B-NBOH hydrochloride
CAS:<p>25B-NBOH hydrochloride is a phenethylamine that exhibits high affinity for serotonin (5-HT) receptors 5-HT2A and 5-HT2C, with pKi values of 8.3 and 9.4, respectively.</p>Fórmula:C17H21BrClNO3Forma y color:SolidPeso molecular:402.711D3/5-HT receptor modulator-1
CAS:<p>D3/5-HT receptor modulator-1 (compound 5i) is a selective antagonist of the dopamine D3 and 5-HT2A receptors, and a partial agonist at the 5-HT1A receptor. It exhibits Ki values of 4.5 nM, 11.9 nM, and 15.3 nM for the dopamine D3, 5-HT2A, and 5-HT1A receptors respectively. The compound shows lower affinity for the dopamine D2 receptor, 5-HT2C receptor, and hERG channel. D3/5-HT receptor modulator-1 possesses atypical antipsychotic properties.</p>Fórmula:C24H29N3O2Forma y color:SolidPeso molecular:391.506CB2R/5-HT1AR agonist 1
CAS:<p>Compound 2o, also known as CB2R/5-HT1AR agonist 1, serves as a partial orally active agonist for the CB2 receptor (EC50 = 479.6 nM) and a full agonist for the 5-HT1A receptor (EC50 = 2.7 μM). This compound demonstrates both anti-anxiety and anti-depressive effects and has favorable pharmacokinetic properties [1].</p>Fórmula:C24H33NO3Forma y color:SolidPeso molecular:383.52SB 243213 hydrochloride
CAS:SB 243213 hydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8).ItFórmula:C22H20ClF3N4O2Pureza:98%Forma y color:SolidPeso molecular:464.87SB 243213 dihydrochloride
CAS:SB 243213 dihydrochloride is an orally active, selective and high-affinity antagonist of 5-hydroxytryptamine (5-HT)2C receptor(pKi of 9.37 and a pKb of 9.8 forFórmula:C22H21Cl2F3N4O2Pureza:98%Forma y color:SolidPeso molecular:501.335-HT6R/MAO-B modulator 1
5-HT6R/MAO-B modulator 1 blocks 5-HT6R and permanently inhibits MAO-B, protects glial cells, and reverses memory loss.Fórmula:C33H38N4O3SForma y color:SolidPeso molecular:570.748 Hydroxy PIPAT oxalate
CAS:8 Hydroxy PIPAT oxalate is a selective 5-HT1A receptor agonist that enhances the spontaneous release of histamine by promoting the degranulation of mast cells in guinea pig and human intestinal preparations. By activating the serotonin signaling pathway, this compound demonstrates potential in regulating gastrointestinal functions and offers insight into the management and suppression of functional gastrointestinal disorders such as irritable bowel syndrome. Its effects in increasing histamine release could play a crucial role in gastrointestinal regulation.Fórmula:C18H24INO5Forma y color:SolidPeso molecular:461.29LK-732
CAS:LK-732 is a thrombin inhibitor with antithrombotic activity. It exhibits dose-dependent inhibition in models of hypercoagulability, with an IC50 value of 1.3 mg/kg. LK-732 is used in cardiovascular and cerebrovascular research.Fórmula:C25H29N5O3SForma y color:SolidPeso molecular:479.59PDE4B/7A-IN-1
CAS:5-HT1A antagonist; Ki=8nM, Kb=0.04nM. PDE4B IC50=80.4μM; PDE7A IC50=151.3μM. Good biofilm penetration, stable, anticognitive, antidepressant.Fórmula:C25H35N3O3Forma y color:SolidPeso molecular:425.56SEP-363856 mesylate
CAS:<p>SEP-363856 (SEP-856) mesylate is an orally active compound that acts as an agonist for both TAAR1 and 5-HT1A receptors. This compound exhibits antipsychotic activity in the central nervous system and has potential for the study of schizophrenia.</p>Fórmula:C10H17NO4S2Forma y color:SolidPeso molecular:279.38THRX-194556
CAS:<p>THRX-194556 is an agonist of the 5-HT4 receptor. It is applicable in the study of gastrointestinal functional disorders and Alzheimer's disease.</p>Fórmula:C28H41N5O5SForma y color:SolidPeso molecular:559.721SB 224289
CAS:SB 224289: selective 5-HT1B antagonist, pKi 8.2, 60x selectivity, effective orally.Fórmula:C32H32N4O3Pureza:98%Forma y color:SolidPeso molecular:520.62AM9405
<p>AM9405: peripheral CB1/5-HT3 agonist, suppresses gut motility, relieves GI disorder symptoms in mice.</p>Fórmula:C24H33BrN2O2Pureza:98%Forma y color:SolidPeso molecular:461.445-HT1A modulator 4
CAS:<p>5-HT1A modulator 4 (Compound 1) is a ligand for the 5-HT receptor, with Ki values of 2.18 μM for 5-HT1A and 19.7 μM for 5-HT2A.</p>Fórmula:C9H14N4Forma y color:SolidPeso molecular:178.234Rodatristat ethyl
CAS:<p>Rodatristat ethyl is an oral TPH1 inhibitor reducing 5-HT levels & lowering PAH at low doses.</p>Fórmula:C29H31ClF3N5O3Pureza:98%Forma y color:SolidPeso molecular:590.04AAZ-A 154 mesylate
CAS:<p>AAZ-A 154 mesylate mesylate is a selective, competitive, and non-hallucinogenic antagonist of 5-HT2AR. It enhances neuronal growth in rodents and produces enduring beneficial behavioral effects.</p>Fórmula:C15H24N2O4SForma y color:SolidPeso molecular:328.43Mesulergine hydrochloride
CAS:5-HT2A and 2C receptor antagonistFórmula:C18H27ClN4O2SPureza:98%Forma y color:SolidPeso molecular:398.955-HT1A antagonist 1
<p>Compound 6f is a potent, selective 5-HT1A receptor blocker (Ki: 35 nM), useful in CNS disorder research.</p>Fórmula:C23H29ClN6O2Forma y color:SolidPeso molecular:456.97Flucopride
CAS:Flucopride (Compound 4a) acts as an acetylcholinesterase inhibitor (AChE) with an IC50 value of 24 nM and serves as a partial agonist for the human 5-HT4 receptor (5-HT4R) with a Ki of 9.6 nM for (h)5-HT4R. It promotes non-amyloidogenic processing of APP in COS-7 cells transiently expressing (h)5-HT4R with an EC50 of 23.0 nM. Flucopride is also likely to exhibit significant gastrointestinal tract (GIT) penetration and blood-brain barrier (BBB) permeability, as determined in PAMPA experiments.Fórmula:C22H33FN2O2Forma y color:SolidPeso molecular:376.51R-137696
CAS:R-137696 is an orally active 5-HT1A receptor agonist that facilitates the relaxation of the proximal stomach. It is utilized in research related to functional dyspepsia.Fórmula:C17H23N3O2Forma y color:SolidPeso molecular:301.38AGH-107
CAS:AGH-107 is a highly selective 5-HT7 receptor agonist that can cross the blood-brain barrier, featuring a Ki value of 6 nM and an EC50 value of 19 nM. Demonstrating high selectivity for central nervous system targets, AGH-107 also exhibits high metabolic stability and low toxicity in HEK-293 and HepG2 cell cultures.Fórmula:C13H12IN3Forma y color:SolidPeso molecular:337.16Serotonin maleate
CAS:<p>Serotonin hydrogen maleate serves as a monoaminergic neurotransmitter and an endogenous 5-HT receptor agonist within the central nervous system (CNS). It also functions as an inhibitor of catechol O-methyltransferase (COMT), exhibiting a Ki value of 44 μM.</p>Fórmula:C14H16N2O5Forma y color:SolidPeso molecular:292.287SB-224289 hydrochloride
CAS:<p>SB-224289 hydrochloride (SB-224289A) is a selective antagonist of 5-HT1B receptor, with anxiolytic effect.</p>Fórmula:C32H33ClN4O3Pureza:97.82% - 98.99%Forma y color:SolidPeso molecular:557.08Arotinolol
CAS:Arotinolol is a nonselective α/β-adrenergic receptor blocker and a vasodilating β-blocker. Arotinolol also shows potency for inhibiting the binding of the radioligand [125I-ICYP] to [5HT1B-serotonergic] receptor sites. It is an antihypertensive agent.Fórmula:C15H21N3O2S3Forma y color:White SolidPeso molecular:371.54SB-399885 hydrochloride
CAS:SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.Fórmula:C18H22Cl3N3O4SPureza:98%Forma y color:SolidPeso molecular:482.817-Desmethyl-agomelatine
CAS:7-Desmethyl-agomelatine, a metabolite of Agomelatine, exhibits lower activity than Agomelatine, which functions as a melatonergic (MT1 and MT2) agonist and 5-HT2C antagonist.Fórmula:C14H15NO2Forma y color:SolidPeso molecular:229.27Pumosetrag Hydrochloride
CAS:Pumosetrag Hydrochloride is an orally available 5-HT3 partial agonist. It is developed for the treatment of irritable bowel syndrome and gastroesophageal reflux disease.Fórmula:C15H18ClN3O2SPureza:98%Forma y color:SolidPeso molecular:339.84Sarizotan
CAS:Sarizotan (EMD 128130) is an orally active compound that acts as an agonist for serotonin 5-HT 1A receptors and dopamine receptors, with IC50 values of 6.5 nM for rat 5-HT 1A, 0.1 nM for human 5-HT 1A, 15.1 nM for rat D 2, 17 nM for human D 2, 6.8 nM for human D 3, and 2.4 nM for human D 4.2.Fórmula:C22H21FN2OForma y color:SolidPeso molecular:348.421Desmethyl cariprazine
CAS:<p>Desmethyl cariprazine is a Cariprazine active metabolite. Cariprazine, an antipsychotic drug candidate, shows a high affinity for the D3 (Ki: 0.085 nM) and D2 (Ki: 0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (2.6 nM).</p>Fórmula:C20H30Cl2N4OPureza:98%Forma y color:SolidPeso molecular:413.38BRL 15572
CAS:BRL 15572 is a useful organic compound for research related to life sciences. The catalog number is T64501 and the CAS number is 734517-40-9.Fórmula:C25H27ClN2OForma y color:SolidPeso molecular:406.952-Methyl-5-HT hydrochloride
CAS:2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine) is a potent and selective 5-HT3 receptor agonist with anti-depressive-like effects.Fórmula:C11H15ClN2OPureza:98%Forma y color:SolidPeso molecular:226.7Flumexadol
CAS:Flumexadol is a selective 5-HT2C receptor agonist with an affinity (Ki) of 25 nM for the (+)-enantiomer and exhibits 40-fold selectivity over the 5-HT2A receptor. It is an orally active, non-narcotic analgesic.Fórmula:C11H12F3NOPureza:98%Forma y color:SolidPeso molecular:231.21
