Receptor 5-HT
Los receptores 5-HT, también conocidos como receptores de serotonina, son un grupo de receptores acoplados a proteínas G (GPCR) que median los efectos de la serotonina, un neurotransmisor involucrado en la regulación del estado de ánimo, la ansiedad, el sueño, el apetito y otros procesos fisiológicos. Estos receptores se dividen en varios subtipos, cada uno con funciones y propiedades farmacológicas distintas. Los moduladores de los receptores 5-HT se estudian ampliamente por su papel en el tratamiento de la depresión, los trastornos de ansiedad y otras afecciones neuropsiquiátricas. En CymitQuimica, ofrecemos una gama de moduladores de receptores 5-HT de alta calidad para apoyar su investigación en neurofarmacología, trastornos del estado de ánimo y señalización GPCR.
Se han encontrado 940 productos de "Receptor 5-HT"
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WAY 163909
CAS:<p>WAY 163909 is an effective and selective agonist of the 5-HT(2C) receptor (Ki: 10.5±1.1 nM).</p>Fórmula:C14H18N2Pureza:98%Forma y color:SolidPeso molecular:214.31S 16924
CAS:<p>S 16924 is a 5-HT 1A agonist with potential anxiolytic effects and may be useful in the study of neurologic disorders.</p>Fórmula:C22H24FNO4Pureza:99.35% - 99.6%Forma y color:SolidPeso molecular:385.43UCSF648
CAS:<p>UCSF648 (Compound 5A6-48) weakly activates MTNR1A and ADRA2A. UCSF648 is a chemical probe for the serotonin receptor 5-HT 5A [1].</p>Fórmula:C15H19ClN2O2SForma y color:SolidPeso molecular:326.84SB 258719 hydrochloride
CAS:<p>Selective 5-HT7 receptor antagonist</p>Fórmula:C18H31ClN2O2SPureza:98%Forma y color:SolidPeso molecular:374.97NPS ALX Compound 4a dihydrochloride
CAS:<p>NPS ALX Compound 4a dihydrochloride is a potent and selective antagonist of 5-HT6 receptor (IC50 of 7.2 nM)</p>Fórmula:C25H27Cl2N3O2SPureza:98%Forma y color:SolidPeso molecular:504.47Lintopride
CAS:<p>Lintopride is an antagonist of 5HT4. It has moderate 5HT3 antagonist properties.</p>Fórmula:C14H19ClN4O2Pureza:98%Forma y color:SolidPeso molecular:310.78Naronapride
CAS:<p>Naronapride (ATI-7505) is a potent agonist of the prokinetic 5-HT4receptor and can be used to study gastrointestinal disorders.</p>Fórmula:C27H41ClN4O5Forma y color:SolidPeso molecular:537.09(R)-DOI hydrochloride
CAS:<p>(R)-DOI hydrochloride is the salt form of 2,5-Dimethoxy-4-iodoamphetamine (DOI), a potent 5-HT2A and 5-HT2C receptor agonist, orally active and hallucinogenic.</p>Fórmula:C11H17ClINO2Pureza:99.88% - >99.99%Forma y color:SolidPeso molecular:357.62Bopindolol (malonate)
CAS:<p>Bopindolol is a non-selective β-adrenergic receptor antagonist.</p>Fórmula:C26H32N2O7Forma y color:SolidPeso molecular:484.549OPC-14523 free base
CAS:<p>OPC-14523, a 5-HT1A receptor agonist, is used potentially for the treatment of depression and neuropathic pain.</p>Fórmula:C23H28ClN3O2Pureza:98%Forma y color:SolidPeso molecular:413.94S 14506 hydrochloride
CAS:<p>S 14506 hydrochloride is a 5-HT1A receptor full agonist.</p>Fórmula:C24H27ClFN3O2Pureza:99.92%Forma y color:SolidPeso molecular:443.94AP-521 (Free base)
CAS:<p>AP-521, a 5-HT1A receptor antagonist, is used potentially for the treatment of anxiety.</p>Fórmula:C20H18N2O3SForma y color:SolidPeso molecular:366.43S 32212 hydrochloride
CAS:<p>S 32212 hydrochloride is a high-affinity inverse agonist at the 5-HT2C receptor and an antagonist at the α2-adrenergic receptor, which is antidepressant .</p>Fórmula:C25H29ClN4O2Pureza:97.11% - 99.57%Forma y color:SolidPeso molecular:452.985-HT2A receptor agonist-2
CAS:<p>Potent 5-HT2A receptor agonist-2 targets 5-HT2A/B/C with EC50 1.7, 0.58, 0.50 nM.</p>Fórmula:C20H21ClN2O3Forma y color:SolidPeso molecular:372.85Alniditan
CAS:<p>Alniditan is a receptors agonist of 5-HT1B/1D in HEK 293 cells (IC50: 1.7 and 1.3 nM). For 5-HT1B/1D receptors, the pKi values are 8.96 and 9.40, respectively.</p>Fórmula:C17H26N4OPureza:98%Forma y color:SolidPeso molecular:302.41PF-184298
CAS:<p>PF-184298 is a serotonin and norepinephrine monoamine reuptake inhibitor (SNRI) that inhibits dopamine reuptake.</p>Fórmula:C15H20Cl2N2OPureza:98.67%Forma y color:SolidPeso molecular:315.24PNU-96391
CAS:<p>PNU-96391 (OSU-6162) is an antagonist of dopamine D2 and a partial agonist of 5-HT2A. PNU-96391 can be used in research on the treatment of chronic diseases.</p>Fórmula:C15H23NO2SPureza:99.53%Forma y color:SolidPeso molecular:281.41Org-12962 hydrochloride
CAS:<p>Org-12962 hydrochloride is a 5-HT2C receptor agonist.</p>Fórmula:C10H12Cl2F3N3Pureza:98%Forma y color:SolidPeso molecular:302.12RS 39604
CAS:<p>potent and selective 5-HT4 antagonist</p>Fórmula:C26H37Cl2N3O6SPureza:98%Forma y color:SolidPeso molecular:590.56Org-12962
CAS:<p>Org-12962: 5-HT2C agonist (pEC50: 7.01), anti-panic in rats, affects 5-HT2A/B (pEC50: 6.38/6.28).</p>Fórmula:C10H11ClF3N3Pureza:98.34%Forma y color:SolidPeso molecular:265.66Zatosetron maleate
CAS:<p>Zatosetron maleate（LY 277359 maleate） is a potent and selective serotonin 5HT3 receptor antagonist for the study of acute migraine.</p>Fórmula:C23H29ClN2O6Pureza:98.07%Forma y color:SolidPeso molecular:464.94Tertatolol
CAS:<p>Tertatolol is an effective antagonist of beta-adrenoceptor and 5-HT receptors.</p>Fórmula:C16H25NO2SPureza:98%Forma y color:SolidPeso molecular:295.44LY 344864 S-enantiomer
CAS:<p>LY 344864 S-enantiomer, the S-enantiomer of LY344864, serves as a 5-HT1F receptor agonist.</p>Fórmula:C21H22FN3OPureza:98%Forma y color:SolidPeso molecular:351.42PRX-08066 Maleic acid
CAS:<p>PRX-08066 Maleic acid is the salt form of PRX-08066.PRX-08066 is a 5-HT receptor 2B antagonist that induces selective vasodilation of the pulmonary artery.</p>Fórmula:C23H21ClFN5O4SPureza:97.59%Forma y color:SolidPeso molecular:517.96Bopindolol fumarate
CAS:<p>Bopindolol fumarate: non-selective β1/β2-adrenoceptor blocker, partial agonist, low β3 affinity, treats hypertension.</p>Fórmula:C27H32N2O7Forma y color:SolidPeso molecular:496.56DR4485 hydrochloride
CAS:<p>5-HT7 antagonist</p>Fórmula:C26H29Cl3N2OPureza:98%Forma y color:SolidPeso molecular:491.885-HT3 antagonist 3
CAS:<p>5-HT3 antagonist 3 (Compound 15b) is a high-affinity 5-HT3 receptor antagonist. It binds to 5-HT3 receptors in rat brain cortical membranes (Ki: 0.25 nM).</p>Fórmula:C20H21N3OPureza:99.9%Forma y color:SolidPeso molecular:319.4Piclozotan
CAS:<p>Piclozotan (anhydrous), a 5-HT1A receptor agonist, demonstrated significant neuroprotective activity in a transient middle cerebral artery occlusion (t-MCAO)</p>Fórmula:C23H24ClN3O2Pureza:98.59%Forma y color:SolidPeso molecular:409.91Lesopitron dihydrochloride
CAS:<p>Lesopitron dihydrochloride with IC50 of 125 nM in rat hippocampal membranes, is a full and selective 5-HT1A receptor agonist.</p>Fórmula:C15H23Cl3N6Pureza:98%Forma y color:SolidPeso molecular:393.74SLV-310
CAS:<p>SLV-310 is a D2 receptor antagonist and 5-HT reuptake receptor inhibitor for the study of neurological disorders such as bipolar disorder and schizophrenia.</p>Fórmula:C25H24FN3O2Pureza:99.39%Forma y color:SolidPeso molecular:417.48S 14063
CAS:<p>S 14063 is a potent 5-HT1A receptor antagonist devoid of beta-adrenoceptor blocking properties.</p>Fórmula:C22H29Cl2N3O2SForma y color:SolidPeso molecular:470.45FG-5893
CAS:<p>FG-5893 is a 5-HT1A agonist and 5-HT2 antagonist with potential anxiolytic activity.</p>Fórmula:C27H29F2N3O2Pureza:98%Forma y color:SolidPeso molecular:465.53(R)-Viloxazine Hydrochloride
CAS:<p>(R)-Viloxazine Hydrochloride, the R-isomer of Viloxazine.</p>Fórmula:C13H20ClNO3Pureza:99.88% - 99.94%Forma y color:SolidPeso molecular:273.76PRX933 hydrochloride
CAS:<p>PRX933 hydrochloride (GW876167 hydrochloride) is an agonist of 5-HT2C receptor and can be used in studies about hypertension acute treatment.</p>Fórmula:C16H22ClN5O2Pureza:99.51% - 99.89%Forma y color:SolidPeso molecular:351.84(R)-(+)-8-Hydroxy-DPAT hydrobromide
CAS:<p>5-HT1A serotonin receptor agonist</p>Fórmula:C16H26BrNOPureza:98%Forma y color:SolidPeso molecular:328.29Trimipramine
CAS:<p>Trimipramine is an antidepressant with an anxiety-reducing sedative component to its action.</p>Fórmula:C20H26N2Pureza:98%Forma y color:SolidPeso molecular:294.43ZM 169369
CAS:<p>ICI 169369, a 5-HT2/5-HT1C antagonist, can evoke endothelium-dependent relaxation in rabbit aorta.</p>Fórmula:C19H20N2SForma y color:SolidPeso molecular:308.44CGS-12066 maleate salt
CAS:<p>CGS-12066 maleate salt is an agonist of 5-HT1B serotonin receptor.</p>Fórmula:C21H21F3N4O4Forma y color:SolidPeso molecular:450.41OPC-14523 hydrochloride
CAS:<p>OPC-14523 hydrochloride, an oral sigma/5-HT1A agonist, shows potent antidepressant activity with strong receptor affinity.</p>Fórmula:C23H29Cl2N3O2Pureza:99.60%Forma y color:SolidPeso molecular:450.4ATC0065
CAS:<p>ATC0065 is a melanin-concentrating hormone receptor 1 antagonist with oral activity.</p>Fórmula:C25H29BrF3N5OForma y color:SolidPeso molecular:552.43Oxetorone fumarate
CAS:<p>Oxetorone fumarate is a non-selective, orally active antagonist of serotonin and 5-HT receptors,used for migraine treatment.</p>Fórmula:C25H25NO6Pureza:99.809%Forma y color:SolidPeso molecular:435.48UCSF686
CAS:<p>UCSF686, a UCSF678 analog, lacks 5-HT5A potency but keeps affinity for 5-HT1A, 5-HT2B, 5-HT7, and serves as a control.</p>Fórmula:C14H19N3O2SForma y color:SolidPeso molecular:293.38NRA-0160
CAS:<p>NRA-0160 is a selective antagonist of dopamine D4 receptor(Ki of 0.48 nM)</p>Fórmula:C24H23F2N3OSPureza:98%Forma y color:SolidPeso molecular:439.52Iprindole
CAS:<p>Iprindole, a tricyclic indole antidepressant, is a dual weak inhibitor of noradrenaline and 5-HT uptake [1].</p>Fórmula:C19H28N2Pureza:99.54%Forma y color:SolidPeso molecular:284.44GTS-21
CAS:<p>GTS-21 (DMXB-A) is an α7 nAChR agonist. GTS-21 suppresses inflammation associated with rheumatoid arthritis by inhibiting RA Th1 cell differentiation.</p>Fórmula:C19H20N2O2Pureza:98%Forma y color:SolidPeso molecular:308.37LY320135
CAS:<p>CB1 receptor antagonist/inverse agonist</p>Fórmula:C24H17NO4Pureza:98%Forma y color:SolidPeso molecular:383.4S-14671
CAS:<p>S-14671: 5-HT1A agonist (pKi 9.3), potent in vivo; 5-HT2A/2C antagonist (pKi 7.8).</p>Fórmula:C22H25N3O2SForma y color:SolidPeso molecular:395.52Nexopamil racemate
CAS:<p>Nexopamil racemate（(Rac)-Nexopamil） is a racemate of Nexopamil. The Nexopamil racemate has potential anti-asthmatic and anti-ulcer activity.</p>Fórmula:C24H40N2O3Pureza:98.61%Forma y color:SolidPeso molecular:404.59LY 302148
CAS:<p>LY 302148 , a 5-HT1F receptor agonist, inhibits neurogenic dural inflammation in guinea pigs. It has potential for migraine therapeutics.</p>Fórmula:C19H23FN4Pureza:98%Forma y color:SolidPeso molecular:326.41Prucalopride hydrochloride
CAS:<p>Prucalopride hydrochloride is a selective agonist of the 5-HT4.</p>Fórmula:C18H27Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:404.33
