Beta amiloide

Amyloid beta-peptide(25-35) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide. Which has shown neurotoxic …

Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic …

Deferoxamine is an iron-chelating agent that binds free iron in a stable complex. It also …

ALZ-801 is an orally available, valine-conjugated prodrug of tramiprosate. ALZ-801 is an advanced and markedly …

Hematoxylin is a dye obtained from the heartwood of logwood (Haematoxylon campechianum Linn., Leguminosae) used …

Rutin, a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic …

Hoechst 34580, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.

Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective …

7-(4-Hydroxyphenyl)-1-phenyl-4-hepten-3-one as a beneficial compound to ameliorate the deleterious effects of Aβ on dendrite integrity …

Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect …

Amyloid β Peptide (42-1)(human) acetate is the inactive form of Amyloid β Peptide (1-42). Amyloid …

(+)-Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity …

4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).

Anatabine shows anti-inflammatory activity in vitro and in vivo, which is mediated in part via …

amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P …

Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-κB and …

δ-secretase inhibitor 11 is an inhibitor of δ-secretase and can be used as a lead …

CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM). CGP52411 blocks …

Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the …

Hoechst 34580 tetrahydrochloride, a cell-permeable fluorescent dye, is used for staining DNA and nuclei.

Putraflavone possesses a good antioxidant activity via its DPPH free radical scavenging.

Isorosmanol possesses antioxidant, neuroprotective and neurotrophic effects, it might be useful in ageing disorders such …

Latrepirdine is an orally active, and neuroactive antagonist of multiple drug targets, including histamine receptors, …

Ezeprogind disulfate is a neurotrophic inducer. Ezeprogind disulfate targets all causes of neurodegeneration including Abeta …

GRGDSPK acetate shows inhibitory activity against integrin-fibronectin binding and can be used in research on …

V-9-M cholecystokinin non-peptide is a precursor compound of cholecystokinin (CCK). Cholecystokinin (CCK) is a brain-intestinal …

Mirabijalone D is a non-competitive inhibitor based on the Dixon plot.It inhibits Aβ1-42 production by …

Davunetide acetate is derived from activity-dependent neuroprotective protein existing in the mammalian CNS. Davunetide acetate …

Schisandrone has strong activities of anti-oxidation, effectively scavenges hydroxyl radical and superoxide anion, and has …

Compound 5936-0108 may has modulationg effect on β-Amyloid (patent WO 2007/134449).

RAGE antagonist peptide acetate is an advanced antagonist of glycation end products (RAGE). RAGE antagonist …

Semagacestat (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch …

Ginsenoside Rg3 possess an ability to inhibit the lung metastasis of tumor cells via inhibition …

TABERSONINE HYDROCHLORIDE is a natural product extracted from the bean of Voacanga africana, is a …

FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain …

8-Deoxygartanin is a butyrylcholinesterase (BChE) selective inhibitor, it exhibits significant inhibition of self-induced α2-amyloid (Aα2) …

Hoechst 34580 xHCl is a cell-permeable fluorescent dye, is used for staining DNA and nuclei.

Dihydroergocristine mesylate(DHEC mesylate) is the methanesulfonic acid salt of dihydroergocristine. It has been used as …

Qingyangshengenin B is a C-21 steroidal glycoside isolated from Qingyangshen. Qingyangshengenin B protects against Aβ …

Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interaction

Ginsenosides are a class of steroid glycosides, and triterpene saponins found exclusively in the plant …

Azeliragon is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as …

beta-Amyrin has antiviral, hepatoprotective, antinociceptive, anti-inflammatory

TRx 0237 (LMTX) mesylate is a second-generation tau protein aggregation inhibitor for the treatment of …

1. Schisantherin B shows good effect in lowering the serum glutamic-pyruvic transaminase level of the …

ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.

Amyloid β-Peptide (1-42) human is a 42-amino acid peptide which plays a key role in …

Amyloid β-Protein (10-20) acetate is a fragment of Amyloid-β peptide, maybe used in the research …

Edonerpic maleate is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).

LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts …

Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β …

Pinostrobin, a potent flavonoid inducer, exerts a neuroprotective effect against Aα2(25-35)-induced neurotoxicity in PC12 cells, …

EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the …

DAPT is a novel γ-secretase inhibitor which reduces the Aβ production (IC50: 20 nM in …

Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK …

TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and …

LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: …

CHF5074, a γ-secretase modulator, reduces Aβ42/40 secretion (IC50: 3.6/18.4 μM).

Ginsenoside Rg2 is one of the major active components of ginseng, act as an NF-κB …

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and …

LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).

MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).

MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.