Beta amiloide
Beta amyloid inhibitors are compounds that specifically target and inhibit the formation or aggregation of beta-amyloid peptides, which are critically involved in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is one of the key pathological features of Alzheimer's, contributing to neuronal dysfunction, synaptic loss, and cognitive decline. By preventing the aggregation of beta-amyloid, these inhibitors are being actively researched as potential therapeutic agents aimed at slowing down or even halting the progression of Alzheimer's disease. At CymitQuimica, we offer a variety of high-quality beta-amyloid inhibitors to support your research in neurodegenerative disorders, protein aggregation, and the development of Alzheimer's therapies.
Se han encontrado 228 productos de "Beta amiloide"
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β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFórmula:C56H76N16O22Pureza:98%Forma y color:SolidPeso molecular:1325.3β-Amyloid (1-16) acetate
β-Amyloid (1-16) acetate, Fragment of β-Amyloid, N-terminal amino group coordinates metal ions (Cu/Zn), used for Alzheimer's disease research.Fórmula:C84H119N27O28·xC2H4O2Pureza:99.55%Forma y color:SolidPeso molecular:1955.04 (free base)G923-0271
CAS:G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.Fórmula:C28H23FN4OForma y color:SolidPeso molecular:450.51Dalidnetug
CAS:Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.Forma y color:LiquidAZD4694
CAS:Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.Fórmula:C14H11FN2O2Forma y color:SolidPeso molecular:258.25Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Fórmula:C6H10CuN6S2Pureza:99.21%Forma y color:SolidPeso molecular:293.86Ref: TM-T40792
1mg37,00€5mg77,00€10mg119,00€25mg263,00€50mg447,00€100mg749,00€200mg1.017,00€1mL*10mM (DMSO)82,00€TH-237A
CAS:TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.Fórmula:C18H17F2NO3Pureza:98%Forma y color:SolidPeso molecular:333.335(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Fórmula:C27H27FN2O4Pureza:98.27%Forma y color:SolidPeso molecular:462.51Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Fórmula:C9H8ClF6NO3S2Forma y color:SolidPeso molecular:391.74Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Fórmula:C19H27N3O4Pureza:97.1% - 99.9%Forma y color:SolidPeso molecular:361.44Simufilam hydrochloride
CAS:Simufilam is an oral, low-toxicity FLNA activator for Alzheimer's research, fixing FLNA structure and reducing pathology.Fórmula:C15H22ClN3OForma y color:SolidPeso molecular:295.81Amyloid β-Protein 10-20 acetate
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research ofFórmula:C73H103N17O18Pureza:97.23%Forma y color:SolidPeso molecular:1506.65TAE-1
CAS:TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
Fórmula:C39H51I3N6O9Pureza:94.58%Forma y color:SolidPeso molecular:1128.57JLK6
CAS:JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signallingFórmula:C10H8ClNO3Pureza:96.50%Forma y color:SolidPeso molecular:225.63Ref: TM-T21890
1mg84,00€5mg152,00€10mg212,00€25mg354,00€50mg504,00€100mg685,00€200mg888,00€1mL*10mM (DMSO)160,00€PBD-150
CAS:PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)Fórmula:C15H20N4O2SPureza:99.68%Forma y color:SolidPeso molecular:320.41PE859
CAS:PE859 is a potent inhibitor of both tau and Aβ aggregation.Fórmula:C28H24N4O2Pureza:98.8% - 99.09%Forma y color:SolidPeso molecular:448.52MK-0752
CAS:MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).
Fórmula:C21H21ClF2O4SPureza:98% - 99.55%Forma y color:SolidPeso molecular:442.9RO4929097
CAS:RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).Fórmula:C22H20F5N3O3Pureza:98.5% - 99.51%Forma y color:SolidPeso molecular:469.4CRANAD 2
CAS:CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.Fórmula:C23H25BF2N2O2Pureza:99.44%Forma y color:Dark Blue To Black PowderPeso molecular:410.27Anle138b
CAS:Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's diseaseFórmula:C16H11BrN2O2Pureza:98.88% - 99.82%Forma y color:SolidPeso molecular:343.171,1'-Methylenedi-2-naphthol
CAS:1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).Fórmula:C21H16O2Pureza:98.91%Forma y color:Light Pink To Light Brown Crystalline PowderPeso molecular:300.35Aftin-4
CAS:Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.Fórmula:C20H28N6OPureza:98.51%Forma y color:SolidPeso molecular:368.48Edonerpic maleate
CAS:Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).Fórmula:C20H25NO6SPureza:98.24%Forma y color:SolidPeso molecular:407.48Frentizole
CAS:Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interactionFórmula:C15H13N3O2SPureza:99.82%Forma y color:SolidPeso molecular:299.35Azeliragon HCl
CAS:Azeliragon: potent oral RAGE inhibitor, blocks Alzheimer's-linked amyloid brain entry.Fórmula:C32H40Cl3N3O2Forma y color:SolidPeso molecular:605.04β-amyloid 1-11 acetate(190436-05-6 free base)
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Fórmula:C58H80N16O24Pureza:>99.99%Forma y color:SolidPeso molecular:1385.37EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Fórmula:C18H18ClMnN2O4Pureza:98.39%Forma y color:SolidPeso molecular:416.74β-Amyloid (31-35)
CAS:β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.Fórmula:C25H47N5O6SPureza:>99.99%Forma y color:SolidPeso molecular:545.74ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Fórmula:C12H12N2OPureza:99.52% - 99.86%Forma y color:SolidPeso molecular:200.24Ref: TM-T7490
1mg34,00€5mg74,00€10mg113,00€25mg222,00€50mg358,00€100mg530,00€500mg1.153,00€1mL*10mM (DMSO)82,00€β-Amyloid 15-21 acetate
β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Fórmula:C45H69N9O11Pureza:99.62%Forma y color:SolidPeso molecular:912.1Dihydroergocristine mesylate
CAS:DHEC mesylate is a vasodilator and α-adrenergic antagonist used for vascular dementia and as a geroprotector.Fórmula:C36H45N5O8SPureza:98.9% - 99.79%Forma y color:SolidPeso molecular:707.84RAGE antagonist peptide acetate
RAGE antagonist peptide acetate blocks RAGE-ligands like HMGB-1, has anti-tumor, and anti-inflammatory effects.Fórmula:C59H105N13O19SPureza:97.17%Forma y color:SolidPeso molecular:1332.61Miridesap
CAS:Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.Fórmula:C16H24N2O6Pureza:≥95%Forma y color:SolidPeso molecular:340.37Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Fórmula:C8H10NO6PPureza:97.52%Forma y color:SolidPeso molecular:247.14PiB
CAS:PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.
Fórmula:C14H12N2OSPureza:97.02%Forma y color:SolidPeso molecular:256.32Cromoglicic acid
CAS:Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
Fórmula:C23H16O11Pureza:99.55% - >99.99%Forma y color:Colorless Crystals From Ethanol + Ether Physical Description Solid (Ntp 1992)Peso molecular:468.37Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Fórmula:C6H7NO2SPureza:99.42% - 99.99%Forma y color:White Crystalline PowderPeso molecular:157.19Semax acetate(80714-61-0 free base)
CAS:Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.Fórmula:C39H55N9O12SPureza:99.46%Forma y color:SolidPeso molecular:873.98LPYFD-NH2 acetate
LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).Fórmula:C35H48N6O10Pureza:96.51%Forma y color:SolidPeso molecular:712.79Ref: TM-T22932L
1mg66,00€5mg130,00€10mg187,00€25mg309,00€50mg439,00€100mg590,00€200mg793,00€1mL*10mM (DMSO)188,00€Colivelin
CAS:Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).Fórmula:C119H206N32O35Pureza:96.56%Forma y color:SolidPeso molecular:2645.14-Hydroxyindole
CAS:4-Hydroxyindole: aromatic, antioxidant, used in cancer treatment and preventing neurodegenerative diseases.Fórmula:C8H7NOPureza:97.05% - 98.13%Forma y color:Off-White Cyrstalline SolidPeso molecular:133.15Solanezumab
CAS:Solanezumab (LY 2062430) is a monoclonal antibody that binds preferentially to soluble amyloid and promotes its clearance from the brain.Pureza:96.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 96.3% (SDS-PAGE); 97.5% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.07 kDaγ-Secretase modulator 13
CAS:γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.Fórmula:C22H23FN6SPureza:99.79%Forma y color:SolidPeso molecular:422.52Dezamizumab
CAS:Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Pureza:95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.82 kDaHomotaurine-d6
CAS:Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.Fórmula:C3D6H3NO3SForma y color:SolidPeso molecular:145.214-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Fórmula:C14H11BrN2SPureza:98%Forma y color:SolidPeso molecular:319.22Nicardipine pyridine metabolite II
CAS:Nicardipine pyridine metabolite II is a biaoctive chemical.Fórmula:C26H27N3O6Forma y color:SolidPeso molecular:477.514-(6-Bromo-2-benzothiazolyl)benzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.Fórmula:C13H9BrN2SPureza:98%Forma y color:SolidPeso molecular:305.19Aftin-5
CAS:Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Fórmula:C19H26N6OForma y color:SolidPeso molecular:354.45Eprodisate
CAS:Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Fórmula:C3H8O6S2Forma y color:SolidPeso molecular:204.22LC kinetic stabilizer-2
CAS:LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.Fórmula:C28H31N3O3Forma y color:SolidPeso molecular:457.56THK-523
CAS:THK-523 selectively binds to tau in Alzheimer's, potent in vitro/vivo. 18F-THK523 excels in tau imaging.Fórmula:C17H15FN2OForma y color:SolidPeso molecular:282.31Neuroinflammatory-IN-2
CAS:Neuroinflammatory-IN-2: anti-neuroinflammatory, inhibits MAO-B (IC50: 10.30µM), 96.33% Aβ1-42 aggregation reduction, neuroprotective in PC-12 cells.Fórmula:C25H27FN2O3Forma y color:SolidPeso molecular:422.49KMS88009
CAS:KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.Fórmula:C19H19NO2Forma y color:SolidPeso molecular:293.36ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Fórmula:C20H14F5N3O2SForma y color:SolidPeso molecular:455.4TC-E 5006
CAS:γ-secretase modulatorFórmula:C29H29F4NO2Pureza:98%Forma y color:SolidPeso molecular:499.54OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Fórmula:C32H46N4O2Forma y color:SolidPeso molecular:518.73YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFórmula:C26H16Br2ClN3Forma y color:SolidPeso molecular:565.69BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Fórmula:C14H12N2SForma y color:SolidPeso molecular:240.32K 01-162
CAS:K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.Fórmula:C15H14BrNForma y color:SolidPeso molecular:288.18Chrysamine G
CAS:Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.Fórmula:C26H16N4Na2O6Forma y color:SolidPeso molecular:526.416Glutaminyl Cyclase Inhibitor 2
CAS:Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).Fórmula:C19H20FN3Pureza:98%Forma y color:SolidPeso molecular:309.38BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Fórmula:C28H20F4N6O3Forma y color:SolidPeso molecular:564.49TML-6
CAS:TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.Fórmula:C30H37NO7Pureza:99.71%Forma y color:SolidPeso molecular:523.62Ref: TM-T37148
1mg94,00€5mg222,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.674,00€1mL*10mM (DMSO)256,00€SV5
CAS:SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.Fórmula:C21H30N2O4S2Forma y color:SolidPeso molecular:438.6Antioxidant agent-2
CAS:Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.Fórmula:C23H26N2O7Forma y color:SolidPeso molecular:442.46BACE1/2-IN-1
CAS:BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.Fórmula:C21H31N5OSForma y color:SolidPeso molecular:401.57JNJ-40418677
CAS:JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.Fórmula:C26H22F6O2Pureza:98%Forma y color:SolidPeso molecular:480.44q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Fórmula:C21H14O6S4Forma y color:SolidPeso molecular:490.59SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Fórmula:C18H18N4O2Pureza:98%Forma y color:SolidPeso molecular:322.36Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFórmula:C22H30N6OForma y color:SolidPeso molecular:394.51AY1511
CAS:AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].Fórmula:C17H14O6Forma y color:SolidPeso molecular:314.29γ-Secretase modulator 12
CAS:γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM.Fórmula:C25H23N3O2Forma y color:SolidPeso molecular:397.47CGP52411
CAS:CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM).Fórmula:C20H15N3O2Pureza:99.78%Forma y color:SolidPeso molecular:329.35Caprospinol
CAS:Caprospinol inhibits β-Amyloid (Aβ) protein neurotoxicity.Fórmula:C33H52O4Pureza:98%Forma y color:SolidPeso molecular:512.76RU-505
CAS:RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.Fórmula:C28H32FN5OPureza:98%Forma y color:SolidPeso molecular:473.58AZ4800
CAS:AZD4800 is a gamma secretase modulators.Fórmula:C24H29N5O3Forma y color:SolidPeso molecular:435.52Astrophloxine
CAS:Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue andFórmula:C27H33IN2Pureza:99.89%Forma y color:SolidPeso molecular:512.47RS-0466
CAS:RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.Fórmula:C17H17N5O2Pureza:98%Forma y color:SolidPeso molecular:323.35Aβ Fibrillization modulator 1
CAS:Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.Fórmula:C17H12N4O3SSeForma y color:SolidPeso molecular:431.33BChE-IN-8
CAS:BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.Fórmula:C18H12BrN7O2Forma y color:SolidPeso molecular:438.24MK-3328
CAS:MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.Fórmula:C14H9FN4OPureza:99.77% - >99.99%Forma y color:SolidPeso molecular:268.25Ref: TM-T16094
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Fórmula:C25H48N6O8S2Pureza:99.72%Forma y color:SolidPeso molecular:624.81Aβ-IN-1
CAS:Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Fórmula:C35H49NPureza:99.1%Forma y color:SoildPeso molecular:483.77Glutaminyl Cyclase Inhibitor 1
CAS:Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.Fórmula:C21H24FN3O2Pureza:99.81%Forma y color:SolidPeso molecular:369.43Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFórmula:C28H27NO3Pureza:99.21%Forma y color:SolidPeso molecular:425.52Ref: TM-T29856
1mg54,00€5mg114,00€10mg178,00€25mg409,00€50mg620,00€100mg982,00€200mg1.314,00€1mL*10mM (DMSO)126,00€PPI-1019
CAS:PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).Fórmula:C36H54N6O5Pureza:95.16% - 98.16%Forma y color:SolidPeso molecular:650.85BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Fórmula:C22H23FN6Pureza:99.63%Forma y color:SolidPeso molecular:390.46amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFórmula:C30H44N2O14Pureza:99.76%Forma y color:SolidPeso molecular:656.68MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
Fórmula:C18H24N2O2Pureza:99.93%Forma y color:SolidPeso molecular:300.4Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Fórmula:C26H27NO6Pureza:98.99%Forma y color:SolidPeso molecular:449.5Ref: TM-T31773
1mg73,00€2mg98,00€5mg165,00€10mg295,00€25mg532,00€50mg800,00€100mg954,00€200mg1.288,00€BMS 433796
CAS:BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.Fórmula:C21H20F2N4O4Pureza:99.17%Forma y color:SolidPeso molecular:430.4NNC 26-9100
CAS:Somatostatin sst4 receptor agonistFórmula:C22H25BrCl2N6SPureza:98%Forma y color:SolidPeso molecular:556.35Aβ/tau aggregation-IN-3
CAS:Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functionalFórmula:C23H22N4O3Forma y color:SolidPeso molecular:402.45QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Fórmula:C29H25N4NaO3S2Forma y color:SolidPeso molecular:564.65RAGE/SERT-IN-1
CAS:RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM andFórmula:C38H41ClN4OSForma y color:SolidPeso molecular:637.28Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Fórmula:C21H17F3N2O3Forma y color:SolidPeso molecular:402.37QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Fórmula:C19H13NO3Forma y color:SolidPeso molecular:303.31ELND007
CAS:ELND007 is a Gamma secretase inhibitor.Fórmula:C19H14F4N4O2SForma y color:SolidPeso molecular:438.4PQM130
CAS:PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.Fórmula:C23H27NO4Pureza:98.73%Forma y color:SolidPeso molecular:381.46
