Beta amiloide
Beta amyloid inhibitors are compounds that specifically target and inhibit the formation or aggregation of beta-amyloid peptides, which are critically involved in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is one of the key pathological features of Alzheimer's, contributing to neuronal dysfunction, synaptic loss, and cognitive decline. By preventing the aggregation of beta-amyloid, these inhibitors are being actively researched as potential therapeutic agents aimed at slowing down or even halting the progression of Alzheimer's disease. At CymitQuimica, we offer a variety of high-quality beta-amyloid inhibitors to support your research in neurodegenerative disorders, protein aggregation, and the development of Alzheimer's therapies.
Se han encontrado 228 productos de "Beta amiloide"
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β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFórmula:C56H76N16O22Pureza:98%Forma y color:SolidPeso molecular:1325.3β-Amyloid (1-16) acetate
β-Amyloid (1-16) acetate, Fragment of β-Amyloid, N-terminal amino group coordinates metal ions (Cu/Zn), used for Alzheimer's disease research.Fórmula:C84H119N27O28·xC2H4O2Pureza:99.55%Forma y color:SolidPeso molecular:1955.04 (free base)G923-0271
CAS:G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.Fórmula:C28H23FN4OForma y color:SolidPeso molecular:450.51Dalidnetug
CAS:Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.Forma y color:LiquidAZD4694
CAS:Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.Fórmula:C14H11FN2O2Forma y color:SolidPeso molecular:258.25Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Fórmula:C6H10CuN6S2Pureza:99.21%Forma y color:SolidPeso molecular:293.86Ref: TM-T40792
1mg37,00€5mg77,00€10mg119,00€25mg263,00€50mg447,00€100mg749,00€200mg1.017,00€1mL*10mM (DMSO)82,00€TH-237A
CAS:TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.Fórmula:C18H17F2NO3Pureza:98%Forma y color:SolidPeso molecular:333.335(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Fórmula:C27H27FN2O4Pureza:98.27%Forma y color:SolidPeso molecular:462.51Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Fórmula:C9H8ClF6NO3S2Forma y color:SolidPeso molecular:391.74Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Fórmula:C19H27N3O4Pureza:97.1% - 99.9%Forma y color:SolidPeso molecular:361.44Simufilam hydrochloride
CAS:Simufilam is an oral, low-toxicity FLNA activator for Alzheimer's research, fixing FLNA structure and reducing pathology.Fórmula:C15H22ClN3OForma y color:SolidPeso molecular:295.81Amyloid β-Protein 10-20 acetate
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research ofFórmula:C73H103N17O18Pureza:97.23%Forma y color:SolidPeso molecular:1506.65TAE-1
CAS:TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
Fórmula:C39H51I3N6O9Pureza:94.58%Forma y color:SolidPeso molecular:1128.57JLK6
CAS:JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signallingFórmula:C10H8ClNO3Pureza:96.50%Forma y color:SolidPeso molecular:225.63Ref: TM-T21890
1mg84,00€5mg152,00€10mg212,00€25mg354,00€50mg504,00€100mg685,00€200mg888,00€1mL*10mM (DMSO)160,00€PBD-150
CAS:PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)Fórmula:C15H20N4O2SPureza:99.68%Forma y color:SolidPeso molecular:320.41PE859
CAS:PE859 is a potent inhibitor of both tau and Aβ aggregation.Fórmula:C28H24N4O2Pureza:98.8% - 99.09%Forma y color:SolidPeso molecular:448.52MK-0752
CAS:MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).
Fórmula:C21H21ClF2O4SPureza:98% - 99.55%Forma y color:SolidPeso molecular:442.9RO4929097
CAS:RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).Fórmula:C22H20F5N3O3Pureza:98.5% - 99.51%Forma y color:SolidPeso molecular:469.4CRANAD 2
CAS:CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.Fórmula:C23H25BF2N2O2Pureza:99.44%Forma y color:Dark Blue To Black PowderPeso molecular:410.27Anle138b
CAS:Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's diseaseFórmula:C16H11BrN2O2Pureza:98.88% - 99.82%Forma y color:SolidPeso molecular:343.17
