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Beta amiloide

Beta amiloide

Beta amyloid inhibitors are compounds that specifically target and inhibit the formation or aggregation of beta-amyloid peptides, which are critically involved in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is one of the key pathological features of Alzheimer's, contributing to neuronal dysfunction, synaptic loss, and cognitive decline. By preventing the aggregation of beta-amyloid, these inhibitors are being actively researched as potential therapeutic agents aimed at slowing down or even halting the progression of Alzheimer's disease. At CymitQuimica, we offer a variety of high-quality beta-amyloid inhibitors to support your research in neurodegenerative disorders, protein aggregation, and the development of Alzheimer's therapies.

Se han encontrado 204 productos de "Beta amiloide"

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  • (D-Asp1)-Amyloid β-Protein (1-42)

    CAS:
    <p>(D-Asp1)-Amyloid β-Protein (1-42), a peptide fragment of amyloid β-protein (Aβ), serves as the primary constituent of vascular and parenchymal amyloid deposits</p>
    Fórmula:C203H311N55O60S
    Forma y color:Solid
    Peso molecular:4514.04
  • Biotin-β-Amyloid (1-42), human TFA


    <p>Biotin-β-Amyloid (1-42), human TFA, also known as Biotin-Amyloid β-Peptide (1-42) (human) TFA, is a biotin-labeled 42-amino acid peptide implicated in the</p>
    Fórmula:C215H326F3N57O64S2
    Forma y color:Solid
    Peso molecular:4854.36
  • AChE/Aβ-IN-6


    <p>BACE1-IN-15 (compound 4j) serves as an effective inhibitor of BACE1 (β-secretase), efficiently mitigating the copper-induced toxicity of Aβ, with an EC50 value of 0.68 μM.</p>
    Forma y color:Odour Solid
  • (Met(O2)35)-Amyloid β-Protein (1-42)


    <p>(Met(O2)35)-Amyloid β-Protein (1-42) is a peptide [1] .</p>
    Fórmula:C203H311N55O62S
    Forma y color:Solid
    Peso molecular:4546.04
  • (Glu20)-Amyloid β-Protein (1-42)

    CAS:
    <p>(Glu20)-Amyloid β-Protein (1-42) represents a variant of amyloid β-protein (Aβ) that fibrillizes more slowly.</p>
    Fórmula:C199H309N55O62S
    Forma y color:Solid
    Peso molecular:4495.98
  • DDC 2′,3′-O-disulfate


    <p>DDC 2′,3′-O-disulfate (compound 4) inhibits the fibrillization and oligomerization of Aβ42, showing promise for Alzheimer's disease (AD) research [1].</p>
    Fórmula:C17H16O11S2
    Forma y color:Solid
    Peso molecular:460.43
  • β-Amyloid (22-40)

    CAS:
    <p>This synthetic peptide consists of amino acids 22 to 40 of beta amyloid protein.</p>
    Fórmula:C78H135N21O26S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1815.1
  • Amyloid β-Protein (3-42)

    CAS:
    <p>Amyloid β-Protein (3-42), the precursor of Pyr peptide, serves as the foundation of the amyloid template block in Alzheimer's disease when modified to</p>
    Forma y color:Solid
  • β-Amyloid (13-27)

    CAS:
    <p>β-Amyloid (13-27) is a peptide consisting of amino acid of 13 to 27 of beta amyloid protein.</p>
    Fórmula:C84H126N24O24
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1856.05
  • C18 L-erythro Ceramide (d18:1/18:0)

    CAS:
    <p>C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.</p>
    Fórmula:C36H71NO3
    Forma y color:Solid
    Peso molecular:565.95
  • Aβ-IN-8


    <p>Aβ-IN-8, also known as compound 7e, is a potent inhibitor of Aβ aggregation [1].</p>
    Fórmula:C22H16F3N3O3S
    Forma y color:Solid
    Peso molecular:459.44
  • β-Amyloid (11-22)

    CAS:
    <p>β-Amyloid (11-22) is a peptide fragment of β-Amyloid.Beta-amyloid peptide (Abeta), the major constituent of amyloid plaques in the brains of Alzheimer’s</p>
    Fórmula:C70H102N18O18
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1483.67
  • 7-Deoxy-trans-dihydronarciclasine

    CAS:
    <p>7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-</p>
    Fórmula:C14H15NO6
    Forma y color:Solid
    Peso molecular:293.27
  • p-HTAA

    CAS:
    <p>Pentamer Hydrogen Thiophene Acetic Acid (p-HTAA) is a compound that specifically targets and labels amyloid-beta (Aβ) deposits in the brains of living mice [1].</p>
    Fórmula:C24H16O4S5
    Forma y color:Solid
    Peso molecular:528.71
  • mcK6A1


    <p>mcK6A1 serves as an inhibitor of amyloid-β (Aβ) aggregation, selectively binding to the 16KLVFFA21 fragment of Aβ42, leading to the formation of an extended β-sheet structure and preventing the formation of Aβ42 oligomers. This compound is valuable for research into Alzheimer's disease and other amyloid-related disorders.</p>
    Fórmula:C71H99N17O16
    Forma y color:Solid
    Peso molecular:1446.65
  • β-Amyloid (1-16)

    CAS:
    <p>β-Amyloid (1-16) is an amyloidogenic protein fragment with a sequence derived from β-amyloid.</p>
    Fórmula:C84H119N27O28
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1955.04
  • β-Amyloid (33-40)

    CAS:
    <p>β-Amyloid (33-40) is a peptide comprising amino acids 33 to 40 of the beta-amyloid protein.</p>
    Fórmula:C32H58N8O9S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:730.92
  • AC 253

    CAS:
    <p>Amylin (AMY3) receptor antagonist; blocks cAMP, Ca2+, PKA, MAPK, Akt, and cFOS activity; prevents Aβ-induced neuronal death. Cyclic AC 253 variant exists.</p>
    Fórmula:C122H196N40O39
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2847.11
  • Acetyl-Tau Peptide (273-284) amide

    CAS:
    <p>Acetyl-Tau Peptide (273-284) amide inhibits Ac-Aβ(25–35)-NH2 aggregation and models Aβ/Tau interaction.</p>
    Fórmula:C64H116N18O17
    Forma y color:Solid
    Peso molecular:1409.72
  • β-Amyloid (1-9)

    CAS:
    <p>This is an N-terminal fragment of beta amyloid.</p>
    Fórmula:C42H60N14O17
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1033.01
  • Chemerin-9 (149-157) TFA


    <p>Chemerin-9 (149-157) TFA is a peptide located at positions 149-157 of chemerin-9, acting as a ChemR23/CMKLR1 agonist.</p>
    Fórmula:C56H67F3N10O15
    Pureza:99.77%
    Forma y color:Solid
    Peso molecular:1177.18
  • CHF-5022

    CAS:
    <p>CHF-5022 is a nonsteroidal anti-inflammatory drug that selectively inhibits the production of beta-amyloid protein (1-42) (ABETA42).</p>
    Fórmula:C17H12F4O2
    Forma y color:Solid
    Peso molecular:324.27
  • β-Amyloid Protein Precursor 770 (135-155)

    CAS:
    <p>Beta-Amyloid Protein Precursor 770 (135-155)Aβ Protein Precursor 770 (135-155)</p>
    Fórmula:C116H172N35O31S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2617.96
  • 2,3-Dehydrosilybin A

    CAS:
    <p>2,3-Dehydrosilybin A is a useful organic compound for research related to life sciences and the catalog number is T125202.</p>
    Fórmula:C25H20O10
    Forma y color:Solid
    Peso molecular:480.425
  • GSK-3β inhibitor 27


    <p>GSK-3β inhibitor27 (Compound 1c) is a reversible, competitive inhibitor of GSK-3β with an IC50 value of 2.2 μM. It inhibits tau hyperphosphorylation and reduces Aβ protein aggregation, demonstrating metal chelation and neuroprotective potential. GSK-3β inhibitor27 is promising for research into neurodegenerative diseases, such as Alzheimer's disease.</p>
    Fórmula:C16H17ClN4O2
    Forma y color:Solid
    Peso molecular:332.79
  • Anti-Amyloid β Antibody (scFv59)


    <p>Anti-Amyloid Beta Antibody (scFv59) is a human-derived antibody produced in CHO cells that targets Amyloid-β. For isotype control, please refer to Human IgG1 kappa, Isotype Control.</p>
    Forma y color:Odour Liquid
  • 5-FAM-β-Amyloid (1-28)


    <p>5-FAM-β-Amyloid (1-28) is a fluorescently-labeled peptide corresponding to the first 28 amino acids of the β-Amyloid protein.</p>
    Fórmula:C166H219N41O52
    Forma y color:Solid
    Peso molecular:3620.76
  • β-Amyloid (1-17)

    CAS:
    <p>This synthetic peptide consists of amino acids 1 to 17 of beta amyloid protein. This peptide can be employed in beta amyloid solubility studies.</p>
    Fórmula:C90H130N28O29
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2068.2
  • Methoxy-X04

    CAS:
    <p>Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ).</p>
    Fórmula:C23H20O3
    Pureza:98.96%
    Forma y color:Solid
    Peso molecular:344.4
  • 1H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester

    CAS:
    <p>Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。</p>
    Fórmula:C26H34N2O7
    Pureza:99.44%
    Forma y color:Soild
    Peso molecular:486.56
  • β-Amyloid (12-28)

    CAS:
    <p>Amyloid β-peptide fragment; minimum section required to bind to brain proteins.</p>
    Fórmula:C89H135N25O25
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1955.18
  • AZD4694 Precursor

    CAS:
    <p>AZD4694 Precursor used for synthesizing [18F]AZD4694, a high-affinity amyloid-β imaging agent.</p>
    Fórmula:C22H25N3O7
    Forma y color:Solid
    Peso molecular:443.45
  • Biotinoyl tripeptide-1

    CAS:
    <p>Biotinoyl tripeptide-1 can produce hair follicles by promoting scalp micro-circulation and reduce follicle atrophy and aging.</p>
    Fórmula:C24H38N8O6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:566.67
  • β-Amyloid (18-28)

    CAS:
    <p>Intracerebroventricular administration of synthetic peptides Beta-amyloid (12-20), (12-28), and (18-28) causes amnesia in mice.</p>
    Fórmula:C55H81N13O18
    Pureza:98%
    Forma y color:Solid
    Peso molecular:1212.31
  • β-Amyloid (10-20)

    CAS:
    <p>Amyloid β-Protein (10-20) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Amyloid β protein fragment containing the α-</p>
    Fórmula:C71H99N17O16
    Pureza:98%
    Forma y color:Lyophilized Powder
    Peso molecular:1446.65
  • Sabirnetug

    CAS:
    <p>Sabirnetug is a humanized IgG2κ monoclonal antibody that specifically targets the amyloid-β (A4) precursor protein.</p>
    Forma y color:Liquid
  • β-Amyloid (1-20)

    CAS:
    <p>This synthetic peptide consists of amino acids 1 to 20 of beta amyloid protein.</p>
    Fórmula:C113H157N31O32
    Pureza:98%
    Forma y color:Solid
    Peso molecular:2461.7
  • Davunetide

    CAS:
    <p>Davunetide: neuroprotective 8-amino acid peptide, improves daily function in schizophrenia, boosts memory in mild cognitive impairment.</p>
    Fórmula:C36H60N10O12
    Pureza:98%
    Forma y color:Solid
    Peso molecular:824.92
  • SEN177

    CAS:
    <p>SEN177 shows the potential in the research of Huntington's disease that is a potent inhibitor of glutaminyl cyclase (QPCT) with an IC 50 of 0.013μM for glutaminyl-peptide cyclotransferase-like (QPCTL). The Ki value of SEN177 for human glutaminyl cyclase (hQC) is 20 nM. SEN177 significantly reduces the early stages of mutant HTT oligomerisation and reduces the percentage of neurons with Q80 aggregates [1].</p>
    Fórmula:C18H19FN6
    Forma y color:Solid
    Peso molecular:338.38
  • TH-237A

    CAS:
    <p>TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.</p>
    Fórmula:C18H17F2NO3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:333.335
  • AZD4694

    CAS:
    <p>Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.</p>
    Fórmula:C14H11FN2O2
    Forma y color:Solid
    Peso molecular:258.25
  • (Rac)-Z-Phe-Phe-FMK

    CAS:
    <p>(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .</p>
    Fórmula:C27H27FN2O4
    Pureza:98.27%
    Forma y color:Solid
    Peso molecular:462.51
  • Cu(II)GTSM

    CAS:
    <p>Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.</p>
    Fórmula:C6H10CuN6S2
    Pureza:99.21%
    Forma y color:Solid
    Peso molecular:293.86
  • Begacestat

    CAS:
    <p>Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.</p>
    Fórmula:C9H8ClF6NO3S2
    Forma y color:Solid
    Peso molecular:391.74
  • Pyridoxal 5'-phosphate hydrate

    CAS:
    <p>Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,</p>
    Fórmula:C8H10NO6P
    Pureza:97.52%
    Forma y color:Solid
    Peso molecular:247.14
  • 1,1'-Methylenedi-2-naphthol

    CAS:
    <p>1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).</p>
    Fórmula:C21H16O2
    Pureza:98.91%
    Forma y color:Light Pink To Light Brown Crystalline Powder
    Peso molecular:300.35
  • Miridesap

    CAS:
    <p>Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.</p>
    Fórmula:C16H24N2O6
    Pureza:≥95%
    Forma y color:Solid
    Peso molecular:340.37
  • PiB

    CAS:
    <p>PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.</p>
    Fórmula:C14H12N2OS
    Pureza:97.02%
    Forma y color:Solid
    Peso molecular:256.32
  • CRANAD 2

    CAS:
    <p>CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.</p>
    Fórmula:C23H25BF2N2O2
    Pureza:99.44%
    Forma y color:Dark Blue To Black Powder
    Peso molecular:410.27
  • Anle138b

    CAS:
    <p>Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease</p>
    Fórmula:C16H11BrN2O2
    Pureza:98.88% - 99.82%
    Forma y color:Solid
    Peso molecular:343.17