Beta amiloide
Beta amyloid inhibitors are compounds that specifically target and inhibit the formation or aggregation of beta-amyloid peptides, which are critically involved in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is one of the key pathological features of Alzheimer's, contributing to neuronal dysfunction, synaptic loss, and cognitive decline. By preventing the aggregation of beta-amyloid, these inhibitors are being actively researched as potential therapeutic agents aimed at slowing down or even halting the progression of Alzheimer's disease. At CymitQuimica, we offer a variety of high-quality beta-amyloid inhibitors to support your research in neurodegenerative disorders, protein aggregation, and the development of Alzheimer's therapies.
Se han encontrado 228 productos de "Beta amiloide"
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β-Amyloid (1-11)
CAS:Anionic interaction of Beta-amyloid (1-11) with Factor XII is suspected to cause massive activation of the C4 (complement 4) system in the cerebrospinal fluidFórmula:C56H76N16O22Pureza:98%Forma y color:SolidPeso molecular:1325.3β-Amyloid (1-16) acetate
β-Amyloid (1-16) acetate, Fragment of β-Amyloid, N-terminal amino group coordinates metal ions (Cu/Zn), used for Alzheimer's disease research.Fórmula:C84H119N27O28·xC2H4O2Pureza:99.55%Forma y color:SolidPeso molecular:1955.04 (free base)G923-0271
CAS:G923-0271 is a TDP-43 inhibitor that improves disease phenotypes in TDP-43 nematode models and reduces the overexpression of human TDP-43, ALS FTD.Fórmula:C28H23FN4OForma y color:SolidPeso molecular:450.51Dalidnetug
CAS:Dalidnetug is a humanized monoclonal antibody that targets human β-amyloid precursor protein (APP). By specifically binding to APP, Dalidnetug reduces the production of β-amyloid (Aβ), thereby demonstrating activity in clearing β-amyloid. This compound holds potential for research in Alzheimer's disease.Forma y color:LiquidAZD4694
CAS:Flutafuranol (AZD4694/NAV4694) binds beta-amyloid, potential PET tracer for Alzheimer's. Non-F18 version supplied.Fórmula:C14H11FN2O2Forma y color:SolidPeso molecular:258.25Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Fórmula:C6H10CuN6S2Pureza:99.21%Forma y color:SolidPeso molecular:293.86Ref: TM-T40792
1mg37,00€5mg77,00€10mg119,00€25mg263,00€50mg447,00€100mg749,00€200mg1.017,00€1mL*10mM (DMSO)82,00€TH-237A
CAS:TH-237A is a novel neuroprotective agent exhibiting favorable permeation across the blood-brain barrier.Fórmula:C18H17F2NO3Pureza:98%Forma y color:SolidPeso molecular:333.335(Rac)-Z-Phe-Phe-FMK
CAS:(Rac)-Z-Phe-Phe-FMK (Cathepsin L-IN-2) is a cathepsin L inhibitor that inhibits the tendency of β-amyloid to induce apoptotic changes .Fórmula:C27H27FN2O4Pureza:98.27%Forma y color:SolidPeso molecular:462.51Begacestat
CAS:Begacestat (GSI-953) is a potent and selective gamma-secretase inhibitor that inhibits Amyloid-beta, inhibits cleavage of APP,,Alzheimer's disease.Fórmula:C9H8ClF6NO3S2Forma y color:SolidPeso molecular:391.74Semagacestat
CAS:Semagacestat (LY450139) (LY450139) is a γ-secretase blocker for Aβ42/Aβ40/Aβ38 (IC50: 10.9/12.1/12.0 nM) and also inhibits Notch signaling (IC50: 14.1 nM).Fórmula:C19H27N3O4Pureza:97.1% - 99.9%Forma y color:SolidPeso molecular:361.44Simufilam hydrochloride
CAS:Simufilam is an oral, low-toxicity FLNA activator for Alzheimer's research, fixing FLNA structure and reducing pathology.Fórmula:C15H22ClN3OForma y color:SolidPeso molecular:295.81Amyloid β-Protein 10-20 acetate
Amyloid β-Protein 10-20 acetate (Amyloid β-Protein 10-20 acetate (152286-31-2 free base)) is a fragment of Amyloid-β peptide, maybe used in the research ofFórmula:C73H103N17O18Pureza:97.23%Forma y color:SolidPeso molecular:1506.65TAE-1
CAS:TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.
Fórmula:C39H51I3N6O9Pureza:94.58%Forma y color:SolidPeso molecular:1128.57JLK6
CAS:JLK6 was a gamma-secretase inhibitor that does not interfere with Notch signallingFórmula:C10H8ClNO3Pureza:96.50%Forma y color:SolidPeso molecular:225.63Ref: TM-T21890
1mg84,00€5mg152,00€10mg212,00€25mg354,00€50mg504,00€100mg685,00€200mg888,00€1mL*10mM (DMSO)160,00€PBD-150
CAS:PBD-150 is an inhibitor of human glutaminyl cyclase (hQC) Y115E-Y117E variant( ki : 490 nM)Fórmula:C15H20N4O2SPureza:99.68%Forma y color:SolidPeso molecular:320.41PE859
CAS:PE859 is a potent inhibitor of both tau and Aβ aggregation.Fórmula:C28H24N4O2Pureza:98.8% - 99.09%Forma y color:SolidPeso molecular:448.52MK-0752
CAS:MK-0752, a γ-secretase inhibitor, reduces Aβ40 production(IC50=5 nM).
Fórmula:C21H21ClF2O4SPureza:98% - 99.55%Forma y color:SolidPeso molecular:442.9RO4929097
CAS:RO4929097 (RG-4733), a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).Fórmula:C22H20F5N3O3Pureza:98.5% - 99.51%Forma y color:SolidPeso molecular:469.4CRANAD 2
CAS:CRANAD-2, a near-infrared probe, detects amyloid-beta in vivo, increasing fluorescence 70x and shifting blue 90 nm upon binding.Fórmula:C23H25BF2N2O2Pureza:99.44%Forma y color:Dark Blue To Black PowderPeso molecular:410.27Anle138b
CAS:Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's diseaseFórmula:C16H11BrN2O2Pureza:98.88% - 99.82%Forma y color:SolidPeso molecular:343.171,1'-Methylenedi-2-naphthol
CAS:1,1'-Methylenedi-2-naphthol target CYP2C19 - cytochrome P450 family 2 subfamily C member 19 (human).Fórmula:C21H16O2Pureza:98.91%Forma y color:Light Pink To Light Brown Crystalline PowderPeso molecular:300.35Aftin-4
CAS:Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.Fórmula:C20H28N6OPureza:98.51%Forma y color:SolidPeso molecular:368.48Edonerpic maleate
CAS:Edonerpic maleate (T-817 maleate) is a neurotrophic agent which can inhibit amyloid-β peptides (Aβ).Fórmula:C20H25NO6SPureza:98.24%Forma y color:SolidPeso molecular:407.48Frentizole
CAS:Frentizole, an immunosuppressive agent, is an inhibitor of the Aβ-ABAD interactionFórmula:C15H13N3O2SPureza:99.82%Forma y color:SolidPeso molecular:299.35Azeliragon HCl
CAS:Azeliragon: potent oral RAGE inhibitor, blocks Alzheimer's-linked amyloid brain entry.Fórmula:C32H40Cl3N3O2Forma y color:SolidPeso molecular:605.04β-amyloid 1-11 acetate(190436-05-6 free base)
β-amyloid 1-11 acetate is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Fórmula:C58H80N16O24Pureza:>99.99%Forma y color:SolidPeso molecular:1385.37EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Fórmula:C18H18ClMnN2O4Pureza:98.39%Forma y color:SolidPeso molecular:416.74β-Amyloid (31-35)
CAS:β-Amyloid (31-35) (β-Amyloid 31-35) is the shortest sequence of native Amyloid-β peptide.Fórmula:C25H47N5O6SPureza:>99.99%Forma y color:SolidPeso molecular:545.74ARN2966
CAS:ARN2966 is an inhibitor of amyloid precursor protein (APP)and amyloid-β (Aβ) secretion.Fórmula:C12H12N2OPureza:99.52% - 99.86%Forma y color:SolidPeso molecular:200.24Ref: TM-T7490
1mg34,00€5mg74,00€10mg113,00€25mg222,00€50mg358,00€100mg530,00€500mg1.153,00€1mL*10mM (DMSO)82,00€β-Amyloid 15-21 acetate
β-Amyloid 15-21 acetate (Beta-Amyloid (15-21) acetate) is a fragment of Amyloid-β peptide, maybe used in the research of neurological disease.Fórmula:C45H69N9O11Pureza:99.62%Forma y color:SolidPeso molecular:912.1Dihydroergocristine mesylate
CAS:DHEC mesylate is a vasodilator and α-adrenergic antagonist used for vascular dementia and as a geroprotector.Fórmula:C36H45N5O8SPureza:98.9% - 99.79%Forma y color:SolidPeso molecular:707.84RAGE antagonist peptide acetate
RAGE antagonist peptide acetate blocks RAGE-ligands like HMGB-1, has anti-tumor, and anti-inflammatory effects.Fórmula:C59H105N13O19SPureza:97.17%Forma y color:SolidPeso molecular:1332.61Miridesap
CAS:Miridesap (GSK2315698) rapidly depletes SAP in blood, cerebrospinal fluid, and amyloid deposits via liver clearance.Fórmula:C16H24N2O6Pureza:≥95%Forma y color:SolidPeso molecular:340.37Pyridoxal 5'-phosphate hydrate
CAS:Pyridoxal 5'-phosphate hydrate (PLP)(1:x), the active form of vitamin B6, is a cofactor for many different enzymes involved in transamination reactions,Fórmula:C8H10NO6PPureza:97.52%Forma y color:SolidPeso molecular:247.14PiB
CAS:PiB (Pittsburgh Compound-B) is a standard for analysis of 11C-PiB. 11C-PiB is a β-amyloid PET imaging tracer for Alzheimer's disease diagnosis.
Fórmula:C14H12N2OSPureza:97.02%Forma y color:SolidPeso molecular:256.32Cromoglicic acid
CAS:Cromoglicic acid prevents the release of inflammatory chemicals such as histamine from mast cells.
Fórmula:C23H16O11Pureza:99.55% - >99.99%Forma y color:Colorless Crystals From Ethanol + Ether Physical Description Solid (Ntp 1992)Peso molecular:468.37Benzenesulfonamide
CAS:Benzenesulfonamide (Benzosulfonamide) ia an inhibitor of carbonic anhydrases.Fórmula:C6H7NO2SPureza:99.42% - 99.99%Forma y color:White Crystalline PowderPeso molecular:157.19Semax acetate(80714-61-0 free base)
CAS:Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.Fórmula:C39H55N9O12SPureza:99.46%Forma y color:SolidPeso molecular:873.98LPYFD-NH2 acetate
LPYFD-NH2 acetate shows some inhibitory effect on the aggregation of Abeta(1-42).Fórmula:C35H48N6O10Pureza:96.51%Forma y color:SolidPeso molecular:712.79Ref: TM-T22932L
1mg66,00€5mg130,00€10mg187,00€25mg309,00€50mg439,00€100mg590,00€200mg793,00€1mL*10mM (DMSO)188,00€Colivelin
CAS:Colivelin is a neuroprotective peptide and activator of STAT3. Colivelin is a hybrid peptide synthesized to enhance the neuroprotective effects of humanin (HN).Fórmula:C119H206N32O35Pureza:96.56%Forma y color:SolidPeso molecular:2645.14-Hydroxyindole
CAS:4-Hydroxyindole: aromatic, antioxidant, used in cancer treatment and preventing neurodegenerative diseases.Fórmula:C8H7NOPureza:97.05% - 98.13%Forma y color:Off-White Cyrstalline SolidPeso molecular:133.15Solanezumab
CAS:Solanezumab (LY 2062430) is a monoclonal antibody that binds preferentially to soluble amyloid and promotes its clearance from the brain.Pureza:96.3% (SDS-PAGE); 97.5% (SEC-HPLC) - 96.3% (SDS-PAGE); 97.5% (SEC-HPLC)Forma y color:LiquidPeso molecular:144.07 kDaγ-Secretase modulator 13
CAS:γ-Secretase modulator 13 is a γ-secretase modulator (GSMs) that can be used to study Alzheimer's disease and tumors.Fórmula:C22H23FN6SPureza:99.79%Forma y color:SolidPeso molecular:422.52Dezamizumab
CAS:Dezamizumab is a humanized antibody targeting the serum amyloid P component (SAP) to clear amyloid fibrils via macrophage phagocytosis, for research in systemic amyloid diseases.Pureza:95% - 98.2% (SDS-PAGE); 98.7% (SEC-HPLC)Forma y color:LiquidPeso molecular:145.82 kDaHomotaurine-d6
CAS:Homotaurine-d6 is a deuterated compound of Homotaurine. Homotaurine has a CAS number of 3687-18-1. Because of its similarity in structure to the neurotransmitter gamma-aminobutyric acid (GABA), it has GABAergic effects and may be useful as an anticonvulsant. Homotaurine has also been investigated as a potential treatment for Alzheimer's disease. It binds to soluble amyloid beta and inhibits the formation of neurotoxic aggregates that lead to amyloid plaque deposition in the brain. However, clinical trials failed to show improvement compared to placebo.Fórmula:C3D6H3NO3SForma y color:SolidPeso molecular:145.214-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent that binds to Amyloid-β (1-40) (KD: 1.7 nM).Fórmula:C14H11BrN2SPureza:98%Forma y color:SolidPeso molecular:319.22Nicardipine pyridine metabolite II
CAS:Nicardipine pyridine metabolite II is a biaoctive chemical.Fórmula:C26H27N3O6Forma y color:SolidPeso molecular:477.514-(6-Bromo-2-benzothiazolyl)benzenamine
CAS:4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET tracer and can be used in the diagnosis of neurological diseases.Fórmula:C13H9BrN2SPureza:98%Forma y color:SolidPeso molecular:305.19Aftin-5
CAS:Aftin-5 is an inducer of amyloid beta protein 42 (Aβ42). It functions by modifying the ultrastructure of mitochondria, leading to an upregulation of Aβ42 and a downregulation of Aβ38 through a β-secretase and γ-secretase-dependent mechanism. Aftin-5 exhibits mild cytotoxicity in SH-SY5Y, HT22, N2a, and N2a-AβPP695 cells, with IC50 values of 180, 194, 178, and 150 μM, respectively.Fórmula:C19H26N6OForma y color:SolidPeso molecular:354.45Eprodisate
CAS:Eprodisate disrupts protein-glycosaminoglycan binding, halting amyloid fibril formation, potentially delaying AA amyloidosis progression.Fórmula:C3H8O6S2Forma y color:SolidPeso molecular:204.22
