Beta amiloide
Beta amyloid inhibitors are compounds that specifically target and inhibit the formation or aggregation of beta-amyloid peptides, which are critically involved in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is one of the key pathological features of Alzheimer's, contributing to neuronal dysfunction, synaptic loss, and cognitive decline. By preventing the aggregation of beta-amyloid, these inhibitors are being actively researched as potential therapeutic agents aimed at slowing down or even halting the progression of Alzheimer's disease. At CymitQuimica, we offer a variety of high-quality beta-amyloid inhibitors to support your research in neurodegenerative disorders, protein aggregation, and the development of Alzheimer's therapies.
Se han encontrado 228 productos de "Beta amiloide"
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LC kinetic stabilizer-2
CAS:LC Kinetic Stabilizer-2 is a powerful stabilizer for amyloidogenic immunoglobulin light chains (LC), demonstrating significant efficacy with an EC50 of 24 nM.Fórmula:C28H31N3O3Forma y color:SolidPeso molecular:457.56THK-523
CAS:THK-523 selectively binds to tau in Alzheimer's, potent in vitro/vivo. 18F-THK523 excels in tau imaging.Fórmula:C17H15FN2OForma y color:SolidPeso molecular:282.31Neuroinflammatory-IN-2
CAS:Neuroinflammatory-IN-2: anti-neuroinflammatory, inhibits MAO-B (IC50: 10.30µM), 96.33% Aβ1-42 aggregation reduction, neuroprotective in PC-12 cells.Fórmula:C25H27FN2O3Forma y color:SolidPeso molecular:422.49KMS88009
CAS:KMS88009 is an amyloid-β aggregation inhibitor that acts by ameliorating neurodegenerative disorder.Fórmula:C19H19NO2Forma y color:SolidPeso molecular:293.36ELND006
CAS:ELND006, an oral Alzheimer's drug, has improved bioavailability as a nanosuspension, and food doesn't affect it.Fórmula:C20H14F5N3O2SForma y color:SolidPeso molecular:455.4TC-E 5006
CAS:γ-secretase modulatorFórmula:C29H29F4NO2Pureza:98%Forma y color:SolidPeso molecular:499.54OAB-14
CAS:OAB-14, a Bexarotene derivative, enhances β-amyloid clearance and cognitive function in APP/PS1 mice, improving Alzheimer's symptoms.Fórmula:C32H46N4O2Forma y color:SolidPeso molecular:518.73YIAD-0205
CAS:YIAD-0205, an orally administered inhibitor of Aβ(1-42) aggregation, has exhibited in vivo efficacy in a 5XFAD transgenic mouse model that harbors five familialFórmula:C26H16Br2ClN3Forma y color:SolidPeso molecular:565.69BTA-1
CAS:BTA-1 is an uncharged derivative of thioflavin-T that has high affinity for Aβ fibrils and shows very good brain entry and clearance [1].Fórmula:C14H12N2SForma y color:SolidPeso molecular:240.32K 01-162
CAS:K 01-162 binds and destabilizes AβO (β-amyloid), with an EC50 of 80 nM.Fórmula:C15H14BrNForma y color:SolidPeso molecular:288.18Chrysamine G
CAS:Chrysamine G, Congo red analog, blocks Aβ toxicity, probes Alzheimer's amyloid.Fórmula:C26H16N4Na2O6Forma y color:SolidPeso molecular:526.416Glutaminyl Cyclase Inhibitor 2
CAS:Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor (IC50: 1.23 μM).Fórmula:C19H20FN3Pureza:98%Forma y color:SolidPeso molecular:309.38BuChE-IN-2
CAS:BuChE-IN-2 inhibits BuChE (IC50: 1.28 μM), NO (0.67 μM), Aβ, ROS, chelates Cu2+, penetrates BBB, used in Alzheimer's research.Fórmula:C28H20F4N6O3Forma y color:SolidPeso molecular:564.49TML-6
CAS:TML-6, an oral derivative of curcumin, may help in Alzheimer's research by targeting amyloid production and various molecular pathways.Fórmula:C30H37NO7Pureza:99.71%Forma y color:SolidPeso molecular:523.62Ref: TM-T37148
1mg94,00€5mg222,00€10mg356,00€25mg708,00€50mg1.063,00€100mg1.674,00€1mL*10mM (DMSO)256,00€SV5
CAS:SV5: potent anti-Alzheimer's, protects SHSY-5Y from Aβ1-42 death, stable with optimal pharmacology in plasma, antioxidant, neuroprotective.Fórmula:C21H30N2O4S2Forma y color:SolidPeso molecular:438.6Antioxidant agent-2
CAS:Antioxidant agent-2 (3c), BBB-permeable, selectively chelates metals; shows neuroprotection, fights liver damage in Alzheimer's research.Fórmula:C23H26N2O7Forma y color:SolidPeso molecular:442.46BACE1/2-IN-1
CAS:BACE1/2-IN-1 inhibits BACE1/2 with IC50s of 0.01μM/0.0053μM, has better permeability and lower Pgp efflux but reduced metabolic stability.Fórmula:C21H31N5OSForma y color:SolidPeso molecular:401.57JNJ-40418677
CAS:JNJ-40418677 is a γ-secretase modulator that selectively blocks γ-site cleavage of the APP without affecting the processing of Notch.Fórmula:C26H22F6O2Pureza:98%Forma y color:SolidPeso molecular:480.44q-FTAA
CAS:q-FTAA targets Aβ1-42 fibrils (330-630 nM) and ADPBC (300-500 nM), useful in Alzheimer's disease research.Fórmula:C21H14O6S4Forma y color:SolidPeso molecular:490.59SEN-1269
CAS:SEN-1269 prevents amyloid-β aggregation, shields neurons, and improves memory by hindering Aβ(1-42)-induced issues.Fórmula:C18H18N4O2Pureza:98%Forma y color:SolidPeso molecular:322.36Glutaminyl Cyclase Inhibitor 5
Glutaminyl Cyclase Inhibitor 5 is a potent, selective inhibitor of human glutaminyl cyclase (hQC), demonstrating an inhibition concentration half-max (IC 50) ofFórmula:C22H30N6OForma y color:SolidPeso molecular:394.51AY1511
CAS:AY1511 is a low cytotoxic inhibitor of amyloid β (Aβ) aggregation [1].Fórmula:C17H14O6Forma y color:SolidPeso molecular:314.29γ-Secretase modulator 12
CAS:γ-Secretase modulator 12 (Compound 1a) is a selective compound that effectively reduces amyloid-β42 (Aβ42) levels with an IC50 of 0.39 μM.Fórmula:C25H23N3O2Forma y color:SolidPeso molecular:397.47CGP52411
CAS:CGP52411 is an orally active, and ATP-competitive inhibitor of EGFR (IC50: 0.3 μM).Fórmula:C20H15N3O2Pureza:99.78%Forma y color:SolidPeso molecular:329.35Caprospinol
CAS:Caprospinol inhibits β-Amyloid (Aβ) protein neurotoxicity.Fórmula:C33H52O4Pureza:98%Forma y color:SolidPeso molecular:512.76RU-505
CAS:RU-505 is an interaction inhibitor of Aβ-fibrinogen that acts by rescuing altered thrombosis and cognitive decline in Alzheimer's disease mice.Fórmula:C28H32FN5OPureza:98%Forma y color:SolidPeso molecular:473.58AZ4800
CAS:AZD4800 is a gamma secretase modulators.Fórmula:C24H29N5O3Forma y color:SolidPeso molecular:435.52Astrophloxine
CAS:Astrophloxine is a fluorescent imaging probe that targets antiparallel dimers.Astrophloxine can be used to detect aggregated Aβ in brain tissue andFórmula:C27H33IN2Pureza:99.89%Forma y color:SolidPeso molecular:512.47RS-0466
CAS:RS-0466 is an β-amyloid-induced cytotoxicity inhibitor.Fórmula:C17H17N5O2Pureza:98%Forma y color:SolidPeso molecular:323.35Aβ Fibrillization modulator 1
CAS:Aβ Fibrillization Modulator 1 stabilizes amyloid-beta (Aβ) monomers, preventing their aggregation into fibrils.Fórmula:C17H12N4O3SSeForma y color:SolidPeso molecular:431.33BChE-IN-8
CAS:BChE-IN-8, compound 20, is a potent oral BChE inhibitor effective on eqBChE and hBChE, crosses blood-brain barrier, and may help in Alzheimer's research.Fórmula:C18H12BrN7O2Forma y color:SolidPeso molecular:438.24MK-3328
CAS:MK-3328, a potential Alzheimer's drug, binds β-Amyloid with strong affinity (IC50:10.5 nM) and may serve as a PET ligand to gauge plaque load.Fórmula:C14H9FN4OPureza:99.77% - >99.99%Forma y color:SolidPeso molecular:268.25Ref: TM-T16094
1mg315,00€5mg745,00€10mg1.018,00€25mg1.431,00€50mg1.783,00€100mg2.250,00€500mg4.410,00€Ezeprogind disulfate
CAS:Ezeprogind disulfate: neurotrophic inducer targeting neurodegeneration causes like Abeta, tau; for neurological disorder research.Fórmula:C25H48N6O8S2Pureza:99.72%Forma y color:SolidPeso molecular:624.81Aβ-IN-1
CAS:Aβ-IN-1 is a novel, potent and orally active γ-secretase modulator (GSM).Fórmula:C35H49NPureza:99.1%Forma y color:SoildPeso molecular:483.77Glutaminyl Cyclase Inhibitor 1
CAS:Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor (IC50: 0.5 μM) that can be used to study neurological disorders.Fórmula:C21H24FN3O2Pureza:99.81%Forma y color:SolidPeso molecular:369.43Aleplasinin
CAS:Aleplasinin (PAZ 417) is a selective and orally active inhibitor of Plasminogen activator inhibitor-1(PAI-1) and a key negative regulator of the fibrinolyticFórmula:C28H27NO3Pureza:99.21%Forma y color:SolidPeso molecular:425.52Ref: TM-T29856
1mg54,00€5mg114,00€10mg178,00€25mg409,00€50mg620,00€100mg982,00€200mg1.314,00€1mL*10mM (DMSO)126,00€PPI-1019
CAS:PPI-1019 is an APP (β-amyloid A4) inhibitor for the treatment of neurological disorders and the study of Alzheimer's disease (AD).Fórmula:C36H54N6O5Pureza:95.16% - 98.16%Forma y color:SolidPeso molecular:650.85BI-1408
CAS:BI-1408 is a modulator potent of γ secretase (IC50: 0.04 μM for Aβ42).Fórmula:C22H23FN6Pureza:99.63%Forma y color:SolidPeso molecular:390.46amyloid P-IN-1
CAS:amyloid P-IN-1 can be used in studies about diseases with depletion of serum amyloid P components such as Alzheimer's disease, amyloidosis, osteoarthritis, andFórmula:C30H44N2O14Pureza:99.76%Forma y color:SolidPeso molecular:656.68MAO-B-IN-9
CAS:MAO-B-IN-9 is a monoamine oxidase B MAO-B inhibitor (IC50: 0.18 μM) that crosses the blood-brain barrier with potency, selectivity and time-dependence.
Fórmula:C18H24N2O2Pureza:99.93%Forma y color:SolidPeso molecular:300.4Fenlean
CAS:"Fenlean (FLZ) in phase I trial at Chinese Academy's Institute of Pharmacy for Parkinson's treatment."Fórmula:C26H27NO6Pureza:98.99%Forma y color:SolidPeso molecular:449.5Ref: TM-T31773
1mg73,00€2mg98,00€5mg165,00€10mg295,00€25mg532,00€50mg800,00€100mg954,00€200mg1.288,00€BMS 433796
CAS:BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.Fórmula:C21H20F2N4O4Pureza:99.17%Forma y color:SolidPeso molecular:430.4NNC 26-9100
CAS:Somatostatin sst4 receptor agonistFórmula:C22H25BrCl2N6SPureza:98%Forma y color:SolidPeso molecular:556.35Aβ/tau aggregation-IN-3
CAS:Aβ/tau aggregation-IN-3 is a potent inhibitor of amyloid protein aggregation, exhibiting an IC50 value of 0.85 µM in an Aβ-Thioflavin T (Aβ-ThT) functionalFórmula:C23H22N4O3Forma y color:SolidPeso molecular:402.45QM-FN-SO3
CAS:QM-FN-SO3 is a blood-brain barrier (BBB)-penetrable, near-infrared (NIR) probe with aggregation-induced emission (AIE) activity, specifically designed for the detection of Aβ plaques. It exhibits ultra-high signal-to-noise (S/N) ratio, binding affinity, and high-performance NIR emission, making it suitable for in vivo detection of Aβ plaques [1].Fórmula:C29H25N4NaO3S2Forma y color:SolidPeso molecular:564.65RAGE/SERT-IN-1
CAS:RAGE/SERT-IN-1 is a potent, orally active inhibitor of advanced glycation end products (RAGE) and serotonin transporter (SERT), with IC50 values of 8.26 μM andFórmula:C38H41ClN4OSForma y color:SolidPeso molecular:637.28Anti-amyloid agent-1
CAS:Anti-amyloid agent-1 is a potent compound that inhibits amyloid aggregation, offering a promising approach for research into the treatment of amyloidosis [1].Fórmula:C21H17F3N2O3Forma y color:SolidPeso molecular:402.37QR-0217
CAS:QR-0217 is a potent inhibitor of both Aβ1-40 and α-synuclein aggregation, exhibiting an IC50 of 7.5 µM for Aβ1-40.Fórmula:C19H13NO3Forma y color:SolidPeso molecular:303.31ELND007
CAS:ELND007 is a Gamma secretase inhibitor.Fórmula:C19H14F4N4O2SForma y color:SolidPeso molecular:438.4PQM130
CAS:PQM130 is a Feruloyl-Donepezil Hybrid compound against the neurotoxicity induced by Aβ1-42 oligomer (AβO) and shows anti-inflammatory activity.Fórmula:C23H27NO4Pureza:98.73%Forma y color:SolidPeso molecular:381.46
