
Inhibidores de ciclooxigenasa (COX)
Cyclooxygenase (COX) inhibitors are a class of compounds that inhibit the activity of COX enzymes, which play a critical role in the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. In the field of neuroscience, COX inhibitors are extensively studied for their potential to alleviate neuroinflammation, a key factor in the progression of various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By blocking COX activity, these inhibitors may help reduce inflammation in the brain, thereby protecting neurons from damage and slowing disease progression. At CymitQuimica, we offer a wide range of high-quality COX inhibitors to support your research in neuroinflammation, pain management, and the study of neurodegenerative disorders.
Se han encontrado 562 productos de "Inhibidores de ciclooxigenasa (COX)"
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K-80001
CAS:<p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>Fórmula:C20H17FO2Forma y color:SolidPeso molecular:308.35Anti-inflammatory agent 8
CAS:<p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>Fórmula:C18H15N5OS2Forma y color:SolidPeso molecular:381.47Apricoxib
CAS:<p>Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.</p>Fórmula:C19H20N2O3SForma y color:SolidPeso molecular:356.44COX-2/sEH-IN-1
CAS:<p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>Fórmula:C23H18F3N5O3SForma y color:SolidPeso molecular:501.48Naproxen glucuronide
CAS:<p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>Fórmula:C20H22O9Forma y color:SolidPeso molecular:406.38AL-8417
CAS:<p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>Fórmula:C29H34O5Pureza:98%Forma y color:SolidPeso molecular:462.58PD 127443
CAS:<p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>Fórmula:C20H28N2OForma y color:SolidPeso molecular:312.45COX-2-IN-32
CAS:<p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>Fórmula:C25H24O6Pureza:98%Forma y color:SolidPeso molecular:420.45Thiazolinobutazone
CAS:<p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>Fórmula:C22H26N4O2SForma y color:SolidPeso molecular:410.53ASP-6537
CAS:<p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>Fórmula:C17H17N3O3Pureza:98%Forma y color:SolidPeso molecular:311.34COX/5-LOX-IN-1
CAS:<p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>Fórmula:C18H30O3Forma y color:SolidPeso molecular:294.43Pifoxime
CAS:<p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>Fórmula:C15H20N2O3Forma y color:SolidPeso molecular:276.33COX-2-IN-16
CAS:<p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>Fórmula:C19H12BrN3O2Forma y color:SolidPeso molecular:394.22COX-2/5-LOX-IN-3
CAS:<p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>Fórmula:C17H16ClN3O2SForma y color:SolidPeso molecular:361.85ATB-337
CAS:<p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>Fórmula:C23H15Cl2NO2S3Forma y color:SolidPeso molecular:504.47Flosulide
CAS:<p>Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.</p>Fórmula:C16H13F2NO4SPureza:98%Forma y color:SolidPeso molecular:353.34AHR-6293
CAS:<p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>Fórmula:C15H12ClNO3Forma y color:SolidPeso molecular:289.71NCX 466
CAS:<p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>Fórmula:C20H24N2O9Pureza:98%Forma y color:SolidPeso molecular:436.41Etoricoxib HCl
CAS:<p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>Fórmula:C18H16Cl2N2O2SForma y color:SolidPeso molecular:395.30Lobeglitazone Sulfate
CAS:<p>Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.</p>Fórmula:C24H26N4O9S2Pureza:98.69%Forma y color:SolidPeso molecular:578.61
