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Inhibidores de ciclooxigenasa (COX)

Inhibidores de ciclooxigenasa (COX)

Cyclooxygenase (COX) inhibitors are a class of compounds that inhibit the activity of COX enzymes, which play a critical role in the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. In the field of neuroscience, COX inhibitors are extensively studied for their potential to alleviate neuroinflammation, a key factor in the progression of various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By blocking COX activity, these inhibitors may help reduce inflammation in the brain, thereby protecting neurons from damage and slowing disease progression. At CymitQuimica, we offer a wide range of high-quality COX inhibitors to support your research in neuroinflammation, pain management, and the study of neurodegenerative disorders.

Se han encontrado 562 productos de "Inhibidores de ciclooxigenasa (COX)"

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  • K-80001

    CAS:
    <p>K-80001 is a selective RXRα ligand and a COX-1/2 inhibitor, exhibiting IC50 values of 82.9μM for RXRα, 3.4μM for COX-1, and 1.2μM for COX-2, respectively [1].</p>
    Fórmula:C20H17FO2
    Forma y color:Solid
    Peso molecular:308.35
  • Anti-inflammatory agent 8

    CAS:
    <p>Anti-inflammatory agent 8 targets COX-2 over COX-1, IC50 of 0.09 nM, orally bioavailable.</p>
    Fórmula:C18H15N5OS2
    Forma y color:Solid
    Peso molecular:381.47
  • Apricoxib

    CAS:
    <p>Apricoxib: oral NSAID with antiangiogenic, antineoplastic properties; inhibits COX-2, may reduce tumor growth and angiogenesis.</p>
    Fórmula:C19H20N2O3S
    Forma y color:Solid
    Peso molecular:356.44
  • COX-2/sEH-IN-1

    CAS:
    <p>COX-2/sEH-IN-1, oral dual inhibitor: COX-2 (IC50=1.24 μM), sEH (IC50=0.40 μM); boosts anti-inflammatory action, cuts heart risk.</p>
    Fórmula:C23H18F3N5O3S
    Forma y color:Solid
    Peso molecular:501.48
  • Naproxen glucuronide

    CAS:
    <p>Naproxen glucuronide: NSAID, propionic class, eases pain, fever, inflammation. Nonselective COX blocker.</p>
    Fórmula:C20H22O9
    Forma y color:Solid
    Peso molecular:406.38
  • AL-8417

    CAS:
    <p>AL-8417 is an enzyme inhibitor with antioxidant, anti-inflammatory, and cytostatic properties; prevents vitrectomy-induced lens alterations.</p>
    Fórmula:C29H34O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:462.58
  • PD 127443

    CAS:
    <p>PD 127443 is a Leukotriene B4 antagonist, it is also a dual inhibitor of cyclooxygenase and 5-lipoxygenase.</p>
    Fórmula:C20H28N2O
    Forma y color:Solid
    Peso molecular:312.45
  • COX-2-IN-32

    CAS:
    <p>COX-2-IN-32 (Compound 2f) is a dual inhibitor of iNOS and COX-2, known to downregulate NF-κB expression.</p>
    Fórmula:C25H24O6
    Pureza:98%
    Forma y color:Solid
    Peso molecular:420.45
  • Thiazolinobutazone

    CAS:
    <p>Thiazolinobutazone is the 2-amino-2-thiazoline salt of phenylbutazone.</p>
    Fórmula:C22H26N4O2S
    Forma y color:Solid
    Peso molecular:410.53
  • ASP-6537

    CAS:
    <p>ASP-6537 is a selective and reversible inhibitor of cyclooxygenase-1.</p>
    Fórmula:C17H17N3O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:311.34
  • COX/5-LOX-IN-1

    CAS:
    <p>Compound 6b is a potent dual inhibitor of COX/5-LOX with IC50s: 1.07μM (COX-1), 0.55μM (COX-2), 0.28μM (5-LOX) for inflammation research.</p>
    Fórmula:C18H30O3
    Forma y color:Solid
    Peso molecular:294.43
  • Pifoxime

    CAS:
    <p>Pifoxime: a NSAID with COX-1/2 inhibition, used in anti-inflammatory treatment and neuropsychiatric studies.</p>
    Fórmula:C15H20N2O3
    Forma y color:Solid
    Peso molecular:276.33
  • COX-2-IN-16

    CAS:
    <p>COX-2-IN-16: potent, selective oral COX-2 blocker, IC50=102 μM, reduces NO, anti-inflammatory.</p>
    Fórmula:C19H12BrN3O2
    Forma y color:Solid
    Peso molecular:394.22
  • COX-2/5-LOX-IN-3

    CAS:
    <p>COX-2/5-LOX-IN-3 inhibits COX-2/5-LOX with IC50s: COX-1 45.73μM, COX-2 5.45μM, 5-LOX 4.33μM; promising for inflammation research.</p>
    Fórmula:C17H16ClN3O2S
    Forma y color:Solid
    Peso molecular:361.85
  • ATB-337

    CAS:
    <p>S-Diclofenac, an NSAID with H2S-releasing moiety, protects gastric mucosa while inhibiting prostaglandins.</p>
    Fórmula:C23H15Cl2NO2S3
    Forma y color:Solid
    Peso molecular:504.47
  • Flosulide

    CAS:
    <p>Flosulide is an effective selective COX-2 inhibitor for the treatment of inflammatory diseases.</p>
    Fórmula:C16H13F2NO4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:353.34
  • AHR-6293

    CAS:
    <p>AHR-6293 is used to distinguishing the effect of anti-platelet aggregating drug properties and the effect of anti-inflammatory properties.</p>
    Fórmula:C15H12ClNO3
    Forma y color:Solid
    Peso molecular:289.71
  • NCX 466

    CAS:
    <p>cyclooxygenase (COX)-inhibiting nitric oxide (NO) donor</p>
    Fórmula:C20H24N2O9
    Pureza:98%
    Forma y color:Solid
    Peso molecular:436.41
  • Etoricoxib HCl

    CAS:
    <p>Etoricoxib HCl is a synthetic NSAID that inhibits COX-2, blocking prostaglandin production.</p>
    Fórmula:C18H16Cl2N2O2S
    Forma y color:Solid
    Peso molecular:395.30
  • Lobeglitazone Sulfate

    CAS:
    <p>Lobeglitazone Sulfate (CKD-501) is an anti-inflammatory thiazolidinedione that prevents NLRP3 inflammasome activation and is used in T2DM research.</p>
    Fórmula:C24H26N4O9S2
    Pureza:98.69%
    Forma y color:Solid
    Peso molecular:578.61