Inhibidores de ciclooxigenasa (COX)
Cyclooxygenase (COX) inhibitors are a class of compounds that inhibit the activity of COX enzymes, which play a critical role in the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. In the field of neuroscience, COX inhibitors are extensively studied for their potential to alleviate neuroinflammation, a key factor in the progression of various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By blocking COX activity, these inhibitors may help reduce inflammation in the brain, thereby protecting neurons from damage and slowing disease progression. At CymitQuimica, we offer a wide range of high-quality COX inhibitors to support your research in neuroinflammation, pain management, and the study of neurodegenerative disorders.
Se han encontrado 562 productos de "Inhibidores de ciclooxigenasa (COX)"
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FPL 62064
CAS:<p>FPL 62064 is a potent dual inhibitor of 5-lipoxygenase (5-LOX) and COX (IC50 of 3.5 μM and 3.1 μM for RBL-1 cytosolic 5-lipoxygenase and prostaglandin</p>Fórmula:C16H15N3OPureza:98.79%Forma y color:SolidPeso molecular:265.31CAFESTOL
CAS:<p>Cafestol, an ERK inhibitor, suppresses PGE2 and COX-2 by blocking NF-kB in LPS-stimulated RAW264.7 cells.</p>Fórmula:C20H28O3Pureza:97.06% - 99.08%Forma y color:SolidPeso molecular:316.43NS-398
CAS:<p>NS-398 (N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide) is a COX-2 inhibitor wih anti-inflammatory activity.</p>Fórmula:C13H18N2O5SPureza:99% - >99.99%Forma y color:SolidPeso molecular:314.36TFAP
CAS:<p>TFAP (N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide) is a selective cyclooxygenase-1 (COX-1) inhibitor</p>Fórmula:C13H10F3N3OPureza:99.87%Forma y color:SolidPeso molecular:281.23Revaprazan hydrochloride
CAS:<p>Revaprazan hydrochloride (YH1885) is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity.</p>Fórmula:C22H24ClFN4Pureza:99.62% - 99.91%Forma y color:SolidPeso molecular:398.9Byakangelicol
CAS:<p>Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.</p>Fórmula:C17H16O6Pureza:98.78% - 99.55%Forma y color:SolidPeso molecular:316.31Pectolinarigenin
CAS:<p>Pectolinarigenin has hepatoprotective and anti-inflammatory properties, acting through SOD and inhibiting eicosanoids.</p>Fórmula:C17H14O6Pureza:98.67% - 99.88%Forma y color:SolidPeso molecular:314.29Compound Lup-20(29)-en-3-yl acetate
<p>Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.</p>Fórmula:C32H52O2Pureza:98%Forma y color:SolidPeso molecular:468.75N-tert-butyl-α-Phenylnitrone
CAS:<p>N-tert-butyl-α-Phenylnitrone ((Z)-N-benzylidene-2-Methylpropan-2-aMine oxide) inhibits COX2 catalytic activity.</p>Fórmula:C11H15NOPureza:99.46% - 99.84%Forma y color:SolidPeso molecular:177.24CAY10404
CAS:<p>CAY10404: potent COX-1/2 inhibitor; blocks PKB/Akt, MAPK pathways; triggers NSC-LC apoptosis; analgesic, anti-inflammatory, anti-cancer.</p>Fórmula:C17H12F3NO3SPureza:99.02%Forma y color:SolidPeso molecular:367.34Tinoridine hydrochloride
CAS:<p>Tinoridine HCl is an NSAID that inhibits lipid peroxides and renin release, unlike indomethacin and corticosteroids.</p>Fórmula:C17H21ClN2O2SPureza:97.49%Forma y color:SolidPeso molecular:352.88Isofraxidin
CAS:<p>Isofraxidin combats leukemia, ALI, and inflammation by modulating ROS, COX-2, PGE2, TNF-α, and p38/ERK1/2 pathways.</p>Fórmula:C11H10O5Pureza:99.51% - ≥95%Forma y color:SolidPeso molecular:222.19Tolmetin
CAS:<p>Tolmetin (Tolectin) NSAID; acts as a cyclooxygenase inhibitor; classified as an anti-inflammatory.</p>Fórmula:C15H15NO3Pureza:99.74% - >99.99%Forma y color:Off-White Crystalline PowerPeso molecular:257.28[10]-Shogaol
CAS:<p>[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.</p>Fórmula:C21H32O3Pureza:97.64% - 98.65%Forma y color:SolidPeso molecular:332.48α-Spinasterol
CAS:<p>α-Spinasterol is a transient receptor potential vanilloid 1 (TRPV1) antagonist, has anti-inflammatory, antidepressant, antioxidant and antinociceptive effects.</p>Fórmula:C29H48OPureza:97.03% - 99.58%Forma y color:SolidPeso molecular:412.69Mofezolac
CAS:<p>Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000</p>Fórmula:C19H17NO5Pureza:99.29%Forma y color:SolidPeso molecular:339.34Firocoxib
CAS:<p>Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cycooxygenase-2 (COX-2) (IC50 of 0.13 μM), with anti-inflammatory for use in dogs and horses.</p>Fórmula:C17H20O5SPureza:99.84%Forma y color:SolidPeso molecular:336.4Parecoxib
CAS:<p>Parecoxib (SC 69124) is an effective and selective COX-2 inhibitor.</p>Fórmula:C19H18N2O4SPureza:99.71% - 99.78%Forma y color:SolidPeso molecular:370.42Tazofelone
CAS:<p>Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.</p>Fórmula:C18H27NO2SPureza:99.89%Forma y color:SolidPeso molecular:321.48(E)-Ethyl p-methoxycinnamate
CAS:<p>1. (E)-Ethyl p-methoxycinnamate (EPMC) is an anticarcinogenic agent. 2. (E)-Ethyl p-methoxycinnamate (EPMC) is a glutathion S tranferase inhibitor.</p>Fórmula:C12H14O3Pureza:97.43%Forma y color:SolidPeso molecular:206.24RK33
CAS:<p>"RK33 is a DDX3 inhibitor causing G1 arrest, apoptosis, and radiation sensitization in DDX3-overexpressing cells."</p>Fórmula:C23H20N6O3Pureza:99.04% - 99.72%Forma y color:SolidPeso molecular:428.44Cis-5-Dodecenoic Acid
CAS:<p>Cis-5-Dodecenoic Acid is a monounsaturated fatty acid that has a C12 chain as a backbone and a cis double bond at the C5 position.</p>Fórmula:C12H22O2Pureza:98% - 99.37%Forma y color:SolidPeso molecular:198.3Madecassic acid
CAS:<p>Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.</p>Fórmula:C30H48O6Pureza:98.80% - 99.69%Forma y color:SolidPeso molecular:504.7Gnetol
CAS:<p>Gnetol inhibits butyrylcholinesterase (IC50: 1.3 μM), tyrosinase, melanin synthesis in B16 cells, and AA-induced platelet aggregation.</p>Fórmula:C14H12O4Pureza:98.55% - ≥95%Forma y color:SolidPeso molecular:244.24Columbin
CAS:<p>Columbin: anti-inflammatory, prevents colon cancer, inhibits PLA2 in RBC dose-dependently.</p>Fórmula:C20H22O6Pureza:99.34% - 99.74%Forma y color:SolidPeso molecular:358.39S-(+)-Marmesin
CAS:<p>S-(+)-Marmesin (marmesin) is a coumarin originally isolated from the mature bark of A. marmelos,exhibiting COX-2/5-LOX dual inhibitory activity.</p>Fórmula:C14H14O4Pureza:98.00% - ≥98%Forma y color:SolidPeso molecular:246.26Losartan Carboxaldehyde
CAS:<p>Losartan Carboxaldehyde is an endothelial cyclooxygenase (COX)-2 inhibitor.</p>Fórmula:C22H21ClN6OPureza:99.1%Forma y color:SolidPeso molecular:420.89Esculentoside A
CAS:<p>Esculentoside A dampens inflammation in ALI, modulates T cells, and could treat autoimmune diseases and BXSB mice by adjusting cytokines and renal cells.</p>Fórmula:C42H66O16Pureza:98% - 99.85%Forma y color:SolidPeso molecular:826.96Isoorientin
CAS:<p>Isoorientin (Homoorientin) has antioxidant activity.</p>Fórmula:C21H20O11Pureza:98.84% - 99.93%Forma y color:SolidPeso molecular:448.38Psoralidin
CAS:<p>Psoralidin inhibits Akt phosphorylation and phosphatidylinositol 3-kinase activation and transcriptionally.</p>Fórmula:C20H16O5Pureza:98% - 99.61%Forma y color:SolidPeso molecular:336.342,5-Di-tert-butylhydroquinone
CAS:<p>2,5-Di-tert-butylhydroquinone (BHQ) is an effective and selective endoplasmic reticulum Ca2+-ATPase inhibitor.</p>Fórmula:C14H22O2Pureza:97.11%Forma y color:PelletslargecrystalsPeso molecular:222.32(+)-Catechin Hydrate
CAS:<p>(+)-Catechin Hydrate is an antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological</p>Fórmula:C15H16O7Pureza:99.03% - 99.96%Forma y color:SolidPeso molecular:308.28Chlorotrianisene
CAS:<p>Chlorotrianisene, a synthetic SERM, is orally active, lipophilic, and has estrogenic and antiestrogenic effects.</p>Fórmula:C23H21ClO3Pureza:98.88% - 99.03%Forma y color:Crystals From Methanol Physical Description Small White Crystals Or White Powder Softens At 226°F Odorless (Ntp 1992)Peso molecular:380.86Avicularin
CAS:<p>Avicularin reduces inflammation via ERK pathway in RAW 264.7 cells and hinders lipid buildup in adipocytes by limiting glucose uptake and fatty acid synthesis.</p>Fórmula:C20H18O11Pureza:97.02% - 99.94%Forma y color:White PowderPeso molecular:434.35[8]-Shogaol
CAS:<p>[8]-Shogaol is a component of ginger and maintains anti-inflammatory activity as a cyclooxygenase-2 inhibitor.</p>Fórmula:C19H28O3Pureza:97.01%Forma y color:SolidPeso molecular:304.42Diclofenac Potassium
CAS:<p>Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.</p>Fórmula:C14H10Cl2KNO2Pureza:99.51%Forma y color:White To Yellowish Crystalline PowderPeso molecular:334.24Lumiracoxib
CAS:<p>Lumiracoxib (Prexige) is a novel, selective COX-2 inhibitor with IC50 and Ki of 0.14 μM and 0.06 μM, exhibits 515-fold selectivity over COX-1. Phase 4.</p>Fórmula:C15H13ClFNO2Pureza:96.64% - 99.77%Forma y color:Pale Yellow SolidPeso molecular:293.72(-)-Catechin gallate
CAS:<p>(-)-Catechin gallate inhibits 6PGD, IDH, Beta-secretase, and fights chloroquine-sensitive/resistant Plasmodium falciparum.</p>Fórmula:C22H18O10Pureza:97.74% - >99.99%Forma y color:SolidPeso molecular:442.37Adelmidrol
CAS:<p>Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.</p>Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Forma y color:SolidPeso molecular:274.367,3',4'-Tri-O-methylluteolin
CAS:<p>7,3',4'-Tri-O-methylluteolin is anti-inflammatory, antibacterial, antifungal, and has moderate antitrypanosomal effects (MIC 19.0 ug/ml).</p>Fórmula:C18H16O6Pureza:98.66% - 99.79%Forma y color:SolidPeso molecular:328.32sphondin
CAS:<p>Sphondin inhibits IL-1beta, reduces COX-2 and PGE(2) in A549 cells, and has anticonvulsant, anti-inflammatory, anti-proliferative properties.</p>Fórmula:C12H8O4Pureza:99.9% - ≥95%Forma y color:SolidPeso molecular:216.19Ginsenoside Rb3
CAS:<p>Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.</p>Fórmula:C53H90O22Pureza:98% - 99.98%Forma y color:SolidPeso molecular:1079.27SC-58125
CAS:<p>SC-58125 is a selective cyclooxygenase 2 (COX-2) inhibitor. SC-58125 exhibits antitumor activity, and also inhibits oedema at sites of inflammation.</p>Fórmula:C17H12F4N2O2SPureza:99.57%Forma y color:SolidPeso molecular:384.35Roburic acid
CAS:<p>Roburic acid and phenethyl-trans-ferulate inhibit COX-1 and COX-2.</p>Fórmula:C30H48O2Pureza:98.765% - 99.88%Forma y color:SolidPeso molecular:440.7Tinoridine
CAS:<p>Tinoridine is a quinoline derivative analog that acts by inhibiting the production of cyclooxygenase-2 (COX-2).</p>Fórmula:C17H20N2O2SPureza:99.08%Forma y color:SolidPeso molecular:316.42FK 3311
CAS:<p>FK 3311 (COX-2 Inhibitor V) is a cell permeable and orally available sulfonanilide that acts as a COX-2 inhibitor and non-steroidal anti-inflammatory drug (</p>Fórmula:C15H13F2NO4SPureza:97.98%Forma y color:SolidPeso molecular:341.33Propyphenazone
CAS:<p>Propyphenazone: an anti-inflammatory, analgesic, antipyretic pyrazolone; prodrug; COX-2 inhibitor.</p>Fórmula:C14H18N2OPureza:99.64%Forma y color:SolidPeso molecular:230.31Teriflunomide impurity 3
CAS:<p>Teriflunomide impurity 3 (4-Amino-N-(4-trifluoromethylphenyl)benzamide) is a selective COX-1 inhibitor(IC50 of 30 μM).</p>Fórmula:C14H11F3N2OPureza:99.62%Forma y color:SolidPeso molecular:280.25Otenaproxesul
CAS:<p>Otenaproxesul (ATB 346) is a novel hydrogen sulphide-releasing derivative of naproxen with markedly reduced toxicity.</p>Fórmula:C21H19NO3SPureza:98.76% - 99.13%Forma y color:SolidPeso molecular:365.45Fenoprofen Calcium
CAS:<p>Fenoprofen Calcium is a nonsteroidal, anti-inflammatory antiarthritic agent.</p>Fórmula:C30H26CaO6Pureza:99.24% - 99.66%Forma y color:SolidPeso molecular:522.6
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