Inhibidores de ciclooxigenasa (COX)
Cyclooxygenase (COX) inhibitors are a class of compounds that inhibit the activity of COX enzymes, which play a critical role in the biosynthesis of prostaglandins—lipid compounds that mediate inflammation, pain, and fever. In the field of neuroscience, COX inhibitors are extensively studied for their potential to alleviate neuroinflammation, a key factor in the progression of various neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. By blocking COX activity, these inhibitors may help reduce inflammation in the brain, thereby protecting neurons from damage and slowing disease progression. At CymitQuimica, we offer a wide range of high-quality COX inhibitors to support your research in neuroinflammation, pain management, and the study of neurodegenerative disorders.
Se han encontrado 562 productos de "Inhibidores de ciclooxigenasa (COX)"
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(-)-Epicatechin
CAS:<p>(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization</p>Fórmula:C15H14O6Pureza:98.55% - 98.80%Forma y color:SolidPeso molecular:290.27Licofelone
CAS:<p>Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis.</p>Fórmula:C23H22ClNO2Pureza:99.25%Forma y color:Yellowish SolidPeso molecular:379.88SC-236
CAS:<p>SC-236 (Sc 236) is an orally active and selective inhibitor of COX-2 (IC50 of 0.005 μM and 17.8 μM for COX-2 and COX-1, respectively).</p>Fórmula:C16H11ClF3N3O2SPureza:99.74%Forma y color:SolidPeso molecular:401.79Chebulagic acid
CAS:<p>Chebulagic acid, isolated from the Terminalia chebula Retz, is a COX-LOX dual inhibitor.</p>Fórmula:C41H30O27Pureza:97.82% - 99.8%Forma y color:SolidPeso molecular:954.66(-)-Epicatechin gallate
CAS:<p>(-)-Epicatechin gallate, a catechin isomer and strong antioxidant, affects membrane proteins and alters gA channel function in bilayers.</p>Fórmula:C22H18O10Pureza:99.16% - 99.93%Forma y color:SolidPeso molecular:442.37Flurbiprofen Axetil
CAS:<p>Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.</p>Fórmula:C19H19FO4Pureza:97.58% - 98%Forma y color:SolidPeso molecular:330.35Phenidone
CAS:<p>Phenidone inhibits COX/LOX, reducing rat autoimmune paralysis and lowering blood pressure in hypertensive rats.</p>Fórmula:C9H10N2OPureza:97.24%Forma y color:White Solid Solid CrystallinePeso molecular:162.19Ataquimas
CAS:<p>Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.</p>Fórmula:C11H13N3OPureza:99.96%Forma y color:SolidPeso molecular:203.24Neochlorogenic acid
CAS:<p>Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions.</p>Fórmula:C16H18O9Pureza:99.12% - 99.54%Forma y color:White PowderPeso molecular:354.31Ibuprofen Lysine
CAS:<p>Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.</p>Fórmula:C19H32N2O4Pureza:99.26%Forma y color:CoaPeso molecular:352.473-TERT-BUTYL-4-HYDROXYANISOLE
CAS:<p>3-tert-Butyl-p-hydroxyanisole is an antioxidant which is produced via water chlorination.</p>Fórmula:C11H16O2Pureza:99.65%Forma y color:White Solid WaxyPeso molecular:180.24Diclofenac Epolamine
CAS:<p>Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.</p>Fórmula:C20H24Cl2N2O3Pureza:99.56%Forma y color:SolidPeso molecular:411.32SC-560
CAS:<p>SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors.</p>Fórmula:C17H12ClF3N2OPureza:99.97%Forma y color:SolidPeso molecular:352.74Prim-O-glucosylcimifugin
CAS:<p>Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC stimulated by TNF-alpha, increase the proportion of G0/G1 phase.</p>Fórmula:C22H28O11Pureza:98.57% - 99.92%Forma y color:SolidPeso molecular:468.45RHC 80267
CAS:<p>RHC 80267 (U-57908) is a selective inhibitor of DAGL (IC50 : 4 μM in canine platelets)</p>Fórmula:C20H34N4O4Pureza:99.54%Forma y color:White SolidPeso molecular:394.51ETHYL CAFFEATE
CAS:<p>Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) suppressed the differentiation of naive CD4+ T cells into Th1 in vitro.</p>Fórmula:C11H12O4Pureza:97.79%Forma y color:SolidPeso molecular:208.21Ufenamate
CAS:<p>Ufenamate (Flufenamic acid butyl ester) is an anthranilic acid-based anti-inflammatory drug developed for skin diseases</p>Fórmula:C18H18F3NO2Pureza:99.89%Forma y color:SolidPeso molecular:337.34Veratric acid
CAS:<p>Veratric acid (3,4-Dimethoxybenzoic acid) is a simple benzoic acid derived from plants and fruits with anti-oxidant, anti-inflammation and blood pressure-</p>Fórmula:C9H10O4Pureza:99.44%Forma y color:SolidPeso molecular:182.17Indomethacin farnesil
CAS:<p>Indomethacin farnesil (Infree) is a prodrug of indomethacin. It acts as a nonsteroidal anti-inflammatory drug (NSAID) and disease-modifying anti-rheumatic drug.</p>Fórmula:C34H40ClNO4Pureza:97.29%Forma y color:SolidPeso molecular:562.14N-trans-Feruloyltyramine
CAS:<p>NTF is hepatoprotective, antioxidant, inhibits COX, prevents platelet aggregation, and reduces melanin by downregulating tyrosinase.</p>Fórmula:C18H19NO4Pureza:99.56% - >99.99%Forma y color:SolidPeso molecular:313.35Phenethyl ferulate
CAS:<p>Phenethyl ferulate is a chemopreventive against colon cancer, enhancing apoptosis in tumors and inhibiting COX/5-LOX (IC50: 4.35/5.75 μM).</p>Fórmula:C18H18O4Pureza:99.88% - 99.91%Forma y color:SolidPeso molecular:298.33(S)-Flurbiprofen
CAS:<p>Esflurbiprofen is an inhibitor of COX-1 and COX-2.</p>Fórmula:C15H13FO2Pureza:99.99%Forma y color:White To Yellowish Crystalline PowderPeso molecular:244.26Dehydrodiisoeugenol
CAS:<p>Dehydrodiisoeugenol suppresses COX-2 expression and NF-κB activity, reducing inflammation in LPS-stimulated murine macrophages.</p>Fórmula:C20H22O4Pureza:99.97%Forma y color:SolidPeso molecular:326.39Ketorolac
CAS:<p>Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.</p>Fórmula:C15H13NO3Pureza:99.68%Forma y color:White Crystalline Or White PowderPeso molecular:255.27Xanthohumol
CAS:<p>Xanthohumol, also known as 2', 4, 4'-trihydroxy-6'-methoxy-3'-prenylchalcone or desmethylxanthohumol, is a member of the class of compounds known as 3-</p>Fórmula:C21H22O5Pureza:98.19% - 99.67%Forma y color:Orange PowderPeso molecular:354.4Loxoprofen sodium (dihydrate)
CAS:<p>Loxoprofen sodium dihydrate: Non-steroidal anti-inflammatory with analgesic, antipyretic, antitumor effects; COX-1/COX-2 inhibitor. IC50: 6.5/13.5 μM.</p>Fórmula:C15H21NaO5Forma y color:SolidPeso molecular:304.318Tenidap
CAS:<p>Tenidap (CP-66248) is a selective COX-1 and SLC26A3 inhibitor with anti-inflammatory, analgesic, and anti-rheumatic activities.</p>Fórmula:C14H9ClN2O3SPureza:98.56% - 99.42%Forma y color:SolidPeso molecular:320.75NF-κB/MAPK-IN-1
CAS:<p>NF-κB/MAPK-IN-1 is an NF-κB and MAPK pathway inhibitor. NF-κB/MAPK-IN-1 is used to prevent rheumatoid arthritis (RA).</p>Fórmula:C27H27NO7Pureza:97.03%Forma y color:SolidPeso molecular:477.51Bromfenac sodium hydrate
CAS:<p>Bromfenac sodium hydrate (Bromfenac monosodium salt sesquihydrate) is the sodium salt form of bromfenac, a NSAID with analgesic and anti-inflammatory effects.</p>Fórmula:C15H12BrNO3H2O·NaPureza:91.85% - 99.65%Forma y color:SolidPeso molecular:383.17Oxyphenbutazone
CAS:<p>Oxyphenbutazone: Non-selective COX inhibitor, anti-inflammatory, kills dormant Mycobacterium tuberculosis.</p>Fórmula:C19H20N2O3Pureza:99.41% - 99.88%Forma y color:White To Yellowish White Crystalline Powder SolidPeso molecular:324.37Meloxicam
CAS:<p>Meloxicam (Metacam) is a Nonsteroidal Anti-inflammatory Drug.</p>Fórmula:C14H13N3O4S2Pureza:97.09% - 99.60%Forma y color:Light Yellow SolidPeso molecular:351.40Fenoprofen
CAS:<p>Fenoprofen (LILLY-5385) is a non-steroidal anti-inflammatory compound and a modifier enhancer of the melanocortin receptor, increasing ERK1/2 activation.</p>Fórmula:C15H14O3Pureza:98.4%Forma y color:SolidPeso molecular:242.27(S)-(+)-Ibuprofen
CAS:<p>(S)-(+)-Ibuprofen (Dexibuprofen) , is a non-steroidal anti-inflammatory drug (NSAID), inhibiting cyclooxygenase (COX).</p>Fórmula:C13H18O2Pureza:99.51% - 99.86%Forma y color:Colourless Crystalline SolidPeso molecular:206.28Paradol
CAS:<p>Paradol, a spicy compound in ginger, offers anti-cancer, anti-inflammatory, antioxidant, and neuroprotective benefits.</p>Fórmula:C17H26O3Pureza:98.4% - 98.98%Forma y color:SolidPeso molecular:278.39Fontolizumab
CAS:<p>Fontolizumab (HuZAF) is a humanised IgG1 monoclonal anti-IFN-gamma (IFN-γ) antibody for the study of Crohn's disease.</p>Pureza:95%Forma y color:LiquidPeso molecular:150 (kDa)Aspirin DL-lysine
CAS:<p>Aspirin DL-lysine: a water-soluble, injectable NSAID that may also hinder cancer growth.</p>Fórmula:C15H22N2O6Forma y color:Crystalline SolidPeso molecular:326.35Cadonilimab
CAS:<p>Cadonilimab (AK104) is a tetravalent PD-1/CTLA-4 bispecific humanised antibody that activates T cells by enhancing IL-2 and IFN-γ secretion.</p>Pureza:95% - 95%Forma y color:LiquidImidazole Salicylate
CAS:<p>Imidazole Salicylate, a non-steroidal anti-inflammatory drug, has limited inhibitory effects on prostaglandin synthesis.</p>Fórmula:C10H10N2O3Pureza:98%Forma y color:SolidPeso molecular:206.2Indometacin Farnesil
CAS:Fórmula:C34H40ClNO4Pureza:>98.0%(HPLC)Forma y color:Light yellow to Yellow to Orange clear liquidPeso molecular:562.15Ketorolac-d5
CAS:<p>Ketorolac-d5 is a deuterated compound of ketorolac for isotope tracing. Ketorolac is a non-steroidal anti-inflammatory agent and inhibitor of COX-1 and COX-2.</p>Fórmula:C15H8D5NO3Pureza:98.99%Forma y color:SolidPeso molecular:260.3Nepafenac-d5
CAS:<p>Nepafenac D5 is the deuterium labeled Nepafenac, which is a selective inhibitor of COX-2 .</p>Fórmula:C15H14N2O2Pureza:98%Forma y color:SolidPeso molecular:259.31AHR-10037
CAS:<p>AHR-10037, a NSAID, offers pain relief, fever reduction, safety, and low stomach risk, acting as a prodrug for COX inhibitors.</p>Fórmula:C15H13ClN2O2Pureza:98%Forma y color:SolidPeso molecular:288.73Amfenac
CAS:<p>Amfenac promotes apoptosis in ARPE-19 cell culture.</p>Fórmula:C15H13NO3Forma y color:SolidPeso molecular:255.27Pelubiprofen
CAS:<p>Pelubiprofen is a non-steroidal anti-inflammatory agent and a COX-2 inhibitor, which effectively reduces PGE(2) production by inhibiting COX activity.</p>Fórmula:C16H18O3Pureza:99.69%Forma y color:SolidPeso molecular:258.31COX-2-IN-2
CAS:<p>COX-2-IN-2 selectively inhibits COX2 (IC50: 0.24 μM); COX-2-IN-1 offers anti-inflammatory and pain relief.</p>Fórmula:C17H12FN3O2SPureza:97.62%Forma y color:SolidPeso molecular:341.36COX-2-IN-26
CAS:<p>COX-2-IN-26: Oral, selective COX-2 inhibitor, low IC50s; anti-inflammatory with GI safety.</p>Fórmula:C23H21N7OS3Forma y color:SolidPeso molecular:507.65Loxoprofenol-SRS tromethamine
CAS:<p>Loxoprofenol-SRS tromethamine (HR1405-01), a metabolite of Loxoprofen, is a safe IV NSAID with strong anti-inflammatory and pain relief properties.</p>Fórmula:C19H31NO6Forma y color:SolidPeso molecular:369.45COX-2-IN-24
CAS:<p>COX-2-IN-24 is an orally active COX-2 inhibitor (IC50: 0.17 μM) with anti-inflammatory and hypo-ulcerogenic effects.</p>Fórmula:C24H24BrN5O3S2Forma y color:SolidPeso molecular:574.51COX-2-IN-18
CAS:<p>COX-2-IN-18 is a potent COX-2 inhibitor similar to Celecoxib, showing promise in cancer research. IC50=0.775μM.</p>Fórmula:C18H19N3O3S2Forma y color:SolidPeso molecular:389.49COX-2-IN-14
CAS:<p>COX-2-IN-14 (2a) is a potent, selective COX-2 inhibitor with high affinity and notable anti-inflammatory effects in mice.</p>Fórmula:C18H18N4O6Forma y color:SolidPeso molecular:386.364
